Research Topics
Species | N E RosenthalSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Role of serotonin transporter promoter repeat length polymorphism (5-HTTLPR) in seasonality and seasonal affective disorderN E Rosenthal
National Institute of Mental Health, Clinical Psychobiology Branch, Bethesda, MD 20892 1390, USA
Mol Psychiatry 3:175-7. 1998..02). The 5-HTTLPR short allele contributes to the trait of seasonality and is a risk factor for SAD, providing further evidence for a relationship between genetic variation in the 5-HT transporter (5-HTT) and behavior...
Association between seasonal affective disorder and the 5-HT2A promoter polymorphism, -1438G/AM A Enoch
Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA
Mol Psychiatry 4:89-92. 1999..However, these results should be treated with caution until replicated because of the possibility of false-positive findings in case-control association studies...
Pleiotropy of the serotonin transporter gene for seasonality and neuroticismL Sher
Section on Biological Rhythms, National Institute of Mental Health, Bethesda, Maryland, USA
Psychiatr Genet 10:125-30. 2000..Sibling-pair analysis confirmed that the effects of the 5-HTTLPR are due to genetic pleiotropy rather than population stratification...
Seasonality and pituitary volumeP J Schwartz
Clinical Psychobiology Branch, National Institute of Mental Health, Bethesda, MD 20892 1390, USA
Psychiatry Res 74:151-7. 1997..0%) across seasons in women, whereas it decreased slightly (-4.3%) across seasons in men. The results suggest that neither winter depression nor the change of seasons is associated with a significant change in pituitary size...
Monorhinal odor identification and depression scores in patients with seasonal affective disorderT T Postolache
Section on Biological Rhythms NIMH, Bethesda, MD 20892 1390, USA
J Affect Disord 56:27-35. 1999....
Effects of tryptophan depletion vs catecholamine depletion in patients with seasonal affective disorder in remission with light therapyA Neumeister
National Institute of Mental Health, Clinical Psychobiology Branch, Bethesda, MD, USA
Arch Gen Psychiatry 55:524-30. 1998..Although hypotheses about the therapeutic mechanism of action of light therapy have focused on serotonergic mechanisms, the potential role, if any, of catecholaminergic pathways has not been fully explored...
Greater improvement in summer than with light treatment in winter in patients with seasonal affective disorderT T Postolache
Clinical Psychobiology Branch, NIMH, Bethesda, MD 20892, USA
Am J Psychiatry 155:1614-6. 1998..The authors sought to compare the degree of mood improvement after light treatment with mood improvement in the subsequent summer in patients with seasonal affective disorder...
Winter seasonal affective disorder: a follow-up study of the first 59 patients of the National Institute of Mental Health Seasonal Studies ProgramP J Schwartz
Clinical Psychobiology Branch, NIMH, Bethesda, MD 20892, USA
Am J Psychiatry 153:1028-36. 1996..The purpose of this study was to characterize the long-term course of patients with seasonal affective disorder...
The role of genetic factors in the etiology of seasonal affective disorder and seasonalityL Sher
Clinical Psychobiology Branch, National Institute of Mental Health, Bethesda, MD 20892 1390, USA
J Affect Disord 53:203-10. 1999..Future research may clarify the role of different genes in the development of SAD...
Serotonin 1A receptors, melatonin, and the proportional control thermostat in patients with winter depressionP J Schwartz
Clinical Psychobiology Branch, National Institute of Mental Health, Bethesda, MD 20892 1390, USA
Arch Gen Psychiatry 55:897-903. 1998....
Free thyroxine and thyroid-stimulating hormone levels in patients with seasonal affective disorder and matched controlsL Sher
Section on Biological Rhythms, National Institute of Mental Health, Bethesda, MD 20892 1390, USA
J Affect Disord 56:195-9. 1999..Future research will be needed to determine whether the difference in thyroid function between SAD patients and controls is an epiphenomenon or is related to the biological mechanisms that cause symptoms of SAD...
Early response to light therapy partially predicts long-term antidepressant effects in patients with seasonal affective disorderL Sher
Section on Biological Rhythms, National Institute of Mental Health, Bethesda, MD, USA
J Psychiatry Neurosci 26:336-8. 2001..To determine if the antidepressant effect of 1 hour of light therapy is predictive of the response after 1 and 2 weeks of treatment in patients with seasonal affective disorder (SAD)...
Seasonal variations in mood and behavior among Chinese medical studentsL Han
Clinical Psychobiology Branch, NIMH, Bethesda, MD 20892 1390, USA
Am J Psychiatry 157:133-5. 2000..The goal of this study was to estimate the frequency of seasonal variations in mood and behavior among Chinese medical students...
Case series: pediatric seasonal affective disorder. A follow-up reportJ N Giedd
National Institute of Mental Health, Child Psychiatry Branch, Bethesda, MD 20892, USA
J Am Acad Child Adolesc Psychiatry 37:218-20. 1998..Seasonal affective disorder can occur in children and adolescents, responds to light therapy, and should be considered in the differential diagnosis of pediatric affective symptoms or cyclic school performance...
Self-reported sensitivity to chemical exposures in five clinical populations and healthy controlsS S Nawab
Section on Biological Rhythms, National Institute of Mental Health, Bethesda, MD 20892 1390, USA
Psychiatry Res 95:67-74. 2000..A possible relationship between reported chemical sensitivity and hypothalamic-pituitary-adrenal (HPA)-axis functioning is discussed...
A circadian signal of change of season in patients with seasonal affective disorderT A Wehr
Section o Biological Rhythms, Mood and Anxiety Disorders Program, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892-1390, USA
Arch Gen Psychiatry 58:1108-14. 2001....
Plasma leptin in men and women with seasonal affective disorder and in healthy matched controlsG Cizza
Pediatric and Reproductive Endocrinology Branch, Clinical Psychobiology Branch, National Institute of Child Health and Human Development, NIMH NIH, Bethesda, MD 20892, USA
Horm Metab Res 37:45-8. 2005....
A naturally occurring amino acid substitution of the human serotonin 5-HT2A receptor influences amplitude and timing of intracellular calcium mobilizationN Ozaki
Clinical Psychobiology Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, U S A
J Neurochem 68:2186-93. 1997....
Band-specific electroencephalogram and brain cooling abnormalities during NREM sleep in patients with winter depressionP J Schwartz
Department of Psychiatry, VAMC, Dayton, Ohio 45428, USA
Biol Psychiatry 50:627-32. 2001..Their EEG profiles during NREM sleep resemble the EEG profiles of subjects who have been sleep deprived. Further studies of NREM sleep homeostasis in patients with SAD seem warranted...
