Simon Rosenfeld

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Global consensus theorem and self-organized criticality: unifying principles for understanding self-organization, swarm intelligence and mechanisms of carcinogenesis
    Simon Rosenfeld
    NIH, National Cancer Institute, Rockville, Maryland, USA
    Gene Regul Syst Bio 7:23-39. 2013
  2. pmc Biomolecular self-defense and futility of high-specificity therapeutic targeting
    Simon Rosenfeld
    National Cancer Institute, EPN 3108, 6130 Executive Blvd, Rockville, Maryland 20892, USA
    Gene Regul Syst Bio 5:89-104. 2011
  3. pmc Critical self-organized self-sustained oscillations in large regulatory networks: towards understanding the gene expression initiation
    Simon Rosenfeld
    National Cancer Institute, EPN 3108, 6130 Executive Blvd, Rockville, Maryland 20892, USA
    Gene Regul Syst Bio 5:27-40. 2011
  4. pmc Do DNA microarrays tell the story of gene expression?
    Simon Rosenfeld
    National Cancer Institute, EPN 3108, 6130 Executive Blvd, Rockville, Maryland 20892
    Gene Regul Syst Bio 4:61-73. 2010
  5. pmc Mathematical descriptions of biochemical networks: stability, stochasticity, evolution
    Simon Rosenfeld
    National Cancer Institute, 6130 Executive Blvd, EPN, Rm 3108, Rockville, MD 20852, USA
    Prog Biophys Mol Biol 106:400-9. 2011
  6. pmc Characteristics of transcriptional activity in nonlinear dynamics of genetic regulatory networks
    Simon Rosenfeld
    National Cancer Institute, USA Email
    Gene Regul Syst Bio 3:159-79. 2009
  7. ncbi request reprint Stochastic cooperativity in non-linear dynamics of genetic regulatory networks
    Simon Rosenfeld
    National Cancer Institute, EPN 3108, 6130 Executive Blvd, Bethesda, MD 20892, USA
    Math Biosci 210:121-42. 2007
  8. ncbi request reprint Numerical deconvolution of cDNA microarray signal: simulation study
    Simon Rosenfeld
    Biometry Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, EPN 3136, 6130 Executive Boulevard, Rockville, MD 20892, USA
    Ann N Y Acad Sci 1020:110-23. 2004
  9. ncbi request reprint New developments in cancer-related computational statistics
    Simon Rosenfeld
    Biometry Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, EPN 3136, 6130 Executive Boulevard, Rockville MD 20892, USA
    Ann N Y Acad Sci 1020:22-31. 2004
  10. ncbi request reprint Overview of commonly used bioinformatics methods and their applications
    Izet M Kapetanovic
    Chemopreventive Agent Development Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7322, USA
    Ann N Y Acad Sci 1020:10-21. 2004

Detail Information

Publications14

  1. pmc Global consensus theorem and self-organized criticality: unifying principles for understanding self-organization, swarm intelligence and mechanisms of carcinogenesis
    Simon Rosenfeld
    NIH, National Cancer Institute, Rockville, Maryland, USA
    Gene Regul Syst Bio 7:23-39. 2013
    ....
  2. pmc Biomolecular self-defense and futility of high-specificity therapeutic targeting
    Simon Rosenfeld
    National Cancer Institute, EPN 3108, 6130 Executive Blvd, Rockville, Maryland 20892, USA
    Gene Regul Syst Bio 5:89-104. 2011
    ..It is hypothesized that swarm intelligence is the key to understanding the emergent property of chemoresistance...
  3. pmc Critical self-organized self-sustained oscillations in large regulatory networks: towards understanding the gene expression initiation
    Simon Rosenfeld
    National Cancer Institute, EPN 3108, 6130 Executive Blvd, Rockville, Maryland 20892, USA
    Gene Regul Syst Bio 5:27-40. 2011
    ..The model seems to be simple enough for staging an experiment for verification of its remarkable properties...
  4. pmc Do DNA microarrays tell the story of gene expression?
    Simon Rosenfeld
    National Cancer Institute, EPN 3108, 6130 Executive Blvd, Rockville, Maryland 20892
    Gene Regul Syst Bio 4:61-73. 2010
    ..As to clinical settings, where firm conclusive diagnoses, not the leads for further experimentation, are required, microarrays still have a long way to go until they become a reliable instrument in patient-related decision making...
  5. pmc Mathematical descriptions of biochemical networks: stability, stochasticity, evolution
    Simon Rosenfeld
    National Cancer Institute, 6130 Executive Blvd, EPN, Rm 3108, Rockville, MD 20852, USA
    Prog Biophys Mol Biol 106:400-9. 2011
    ..The focus of attention is placed on mathematical approaches to conceptual modeling of biomolecular networks with special emphasis on dynamic stability, stochasticity and evolution...
  6. pmc Characteristics of transcriptional activity in nonlinear dynamics of genetic regulatory networks
    Simon Rosenfeld
    National Cancer Institute, USA Email
    Gene Regul Syst Bio 3:159-79. 2009
    ..An overall conclusion of the work is that the measurements of mRNA abundances are not truly representative of the functionality of genes and structural fidelity of the genetic codes...
  7. ncbi request reprint Stochastic cooperativity in non-linear dynamics of genetic regulatory networks
    Simon Rosenfeld
    National Cancer Institute, EPN 3108, 6130 Executive Blvd, Bethesda, MD 20892, USA
    Math Biosci 210:121-42. 2007
    ....
  8. ncbi request reprint Numerical deconvolution of cDNA microarray signal: simulation study
    Simon Rosenfeld
    Biometry Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, EPN 3136, 6130 Executive Boulevard, Rockville, MD 20892, USA
    Ann N Y Acad Sci 1020:110-23. 2004
    ..We also employ extreme value considerations to derive plausible cutoff levels for hypothesis testing...
  9. ncbi request reprint New developments in cancer-related computational statistics
    Simon Rosenfeld
    Biometry Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, EPN 3136, 6130 Executive Boulevard, Rockville MD 20892, USA
    Ann N Y Acad Sci 1020:22-31. 2004
    ....
  10. ncbi request reprint Overview of commonly used bioinformatics methods and their applications
    Izet M Kapetanovic
    Chemopreventive Agent Development Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7322, USA
    Ann N Y Acad Sci 1020:10-21. 2004
    ..The goal of these efforts is to develop and identify bioinformatics methods with optimal sensitivity, specificity, and predictive capabilities...