Research Topics
| W J RoganSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Pollutants in breast milkW J Rogan
Office of Clinical Research, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA
Arch Pediatr Adolesc Med 150:981-90. 1996..To review data on the occurrence and toxicity of the commonly reported pesticides and industrial environmental pollutant chemicals in breast milk...- Evidence of effects of environmental chemicals on the endocrine system in childrenWalter J Rogan
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
Pediatrics 112:247-52. 2003..Although endocrine disruption in humans by pollutant chemicals remains largely undemonstrated, the underlying science is sound and the potential for such effects is real... - X-ray evidence of increased asbestos exposure in the US population from NHANES I and NHANES II, 1973-1978. National Health Examination SurveyW J Rogan
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Cancer Causes Control 11:441-9. 2000..At least one indicator of asbestos exposure, mesothelioma, has been increasing in the US for decades. We investigated the prevalence of another indicator, pleural thickening on x-ray, in a defined sample of the US population... - The effect of chelation therapy with succimer on neuropsychological development in children exposed to leadW J Rogan
National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
N Engl J Med 344:1421-6. 2001..It is not known whether treatment to reduce blood lead levels prevents or reduces such impairment... 
Some evidence of effects of environmental chemicals on the endocrine system in childrenWalter J Rogan
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
Int J Hyg Environ Health 210:659-67. 2007..Although endocrine disruption in humans by pollutant chemicals remains largely undemonstrated, the underlying science is sound and the potential for such effects is real...- Health risks and benefits of bis(4-chlorophenyl)-1,1,1-trichloroethane (DDT)Walter J Rogan
Epidemiology Branch, US National Institute of Environmental Health Sciences, P O Box 12233, Research Triangle Park, NC 27709, USA
Lancet 366:763-73. 2005..DDT might be useful in controlling malaria, but the evidence of its adverse effects on human health needs appropriate research on whether it achieves a favourable balance of risk versus benefit... - Isoflavones in urine, saliva, and blood of infants: data from a pilot study on the estrogenic activity of soy formulaYang Cao
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
J Expo Sci Environ Epidemiol 19:223-34. 2009..We plan further longitudinal studies focusing on physical and developmental findings reflecting the effects of estrogen exposure... - Isoflavones in soy infant formula: a review of evidence for endocrine and other activity in infantsAimin Chen
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
Annu Rev Nutr 24:33-54. 2004.... - Comparison of polychlorinated biphenyl levels across studies of human neurodevelopmentMatthew P Longnecker
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
Environ Health Perspect 111:65-70. 2003..S. studies or recent Dutch, German, and northern Québec studies. Our results will facilitate a direct comparison of the findings on PCBs and neurodevelopment when they are published for all 10 studies... - Maternal smoking during pregnancy in relation to child overweight: follow-up to age 8 yearsAimin Chen
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
Int J Epidemiol 35:121-30. 2006..The size of this relation, however, is unclear, as is the age at which it becomes detectable... - Postnatal cadmium exposure, neurodevelopment, and blood pressure in children at 2, 5, and 7 years of ageYang Cao
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA
Environ Health Perspect 117:1580-6. 2009..Adverse health effects of cadmium in adults are well documented, but little is known about the neuropsychological effects of cadmium in children, and no studies of cadmium and blood pressure in children have been conducted... - Birth weight, early weight gain and pubertal maturation: a longitudinal studyY Wang
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Pediatr Obes 7:101-9. 2012..To investigate the effect of birth weight and early weight gain on the timing of various measures of puberty in both girls and boys... - Nonmalarial infant deaths and DDT use for malaria controlAimin Chen
National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
Emerg Infect Dis 9:960-4. 2003..The estimated increases are of the same order of magnitude as the decreases from effective malaria control. Unintended consequences of DDT use need to be part of the discussion of modern vector control policy... - Dermatological findings in children exposed transplacentally to heat-degraded polychlorinated biphenyls in TaiwanB C Gladen
Statistics and Biomathematics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709
Br J Dermatol 122:799-808. 1990..The findings seen in transplacentally exposed children differ from those seen in people directly exposed, particularly in the latter group in higher prevalence of acne... - The human health effects of DDT (dichlorodiphenyltrichloroethane) and PCBS (polychlorinated biphenyls) and an overview of organochlorines in public healthM P Longnecker
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
Annu Rev Public Health 18:211-44. 1997..A recent risk assessment that considered animal data, however, gives a cancer risk estimate for background exposure to dioxin and dioxin-like compounds (e.g. some PCBs) with an upper bound in the range of 10(-4) per year... - Does background postnatal methyl mercury exposure in toddlers affect cognition and behavior?Yang Cao
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
Neurotoxicology 31:1-9. 2010..We conclude that at the present background postnatal MeHg exposure levels of US children, adverse effects on children's IQ and behavior are not detectable... - Are breast-fed infants more resilient? Feeding method and cortisol in infantsYang Cao
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
J Pediatr 154:452-4. 2009..The higher cortisol levels among breast-fed children may be involved in the analgesic effect of breastfeeding... - Lead exposure, IQ, and behavior in urban 5- to 7-year-olds: does lead affect behavior only by lowering IQ?Aimin Chen
Epidemiology Branch, National Institute on Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Pediatrics 119:e650-8. 2007..In addition, either peak blood lead concentration, usually at 2 years old, or the lower blood lead level measured at school age may be the most relevant. Few studies have all of this information... - Exposure to lead in children--how low is low enough?Walter J Rogan
National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA
N Engl J Med 348:1515-6. 2003 - DDT serum concentration and menstruation among young Chinese womenAimin Chen
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, USA
Environ Res 99:397-402. 2005..The study largely suggests no association between DDE and DDT concentrations and menstrual cycle characteristics in young Chinese women, though the weak-to-no correlation of DDE with menstrual cycle length merits further study... - Maternal IQ, child IQ, behavior, and achievement in urban 5-7 year oldsAimin Chen
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, North Carolina 27709, USA
Pediatr Res 59:471-7. 2006..Children with higher IQ have fewer behavior problems, irrespective of the mother's IQ. In the special setting of mothers with IQ <70, children with higher IQ are not at greater risk of behavior problems... - Goitrogenic anions, thyroid-stimulating hormone, and thyroid hormone in infantsYang Cao
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA
Environ Health Perspect 118:1332-7. 2010..U.S. women with higher background perchlorate exposure have higher thyroid-stimulating hormone (TSH) and lower thyroxine (T4). There are no studies with individual measures of thyroid function and these goitrogens available in infants... - IQ and blood lead from 2 to 7 years of age: are the effects in older children the residual of high blood lead concentrations in 2-year-olds?Aimin Chen
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health DHHS, Research Triangle Park, NC 27709, USA
Environ Health Perspect 113:597-601. 2005..The effect of concurrent blood level on IQ may therefore be greater than currently believed... - Do children with falling blood lead levels have improved cognition?Xianchen Liu
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
Pediatrics 110:787-91. 2002..Exposure to lead at levels encountered by urban children impairs cognitive development. An observational study suggested improvement in IQ when blood lead level fell, but the only randomized trial of chelation showed no benefit in IQ... - Breastfeeding and the risk of postneonatal death in the United StatesAimin Chen
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
Pediatrics 113:e435-9. 2004..Assuming causality, however, promoting breastfeeding has the potential to save or delay approximately 720 postneonatal deaths in the United States each year... - The effect of chelation on blood pressure in lead-exposed children: a randomized studyAimin Chen
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, U.S. Department of Health and Human Services, Research Triangle Park, NC 27709, USA
Environ Health Perspect 114:579-83. 2006..Overall, there is no association between blood lead and blood pressure in these children with moderately high lead exposure, nor does chelation with succimer change blood pressure... - A cohort study of behavioral problems and intelligence in children with high prenatal polychlorinated biphenyl exposureTe-Jen Lai
Department of Psychiatry, Chung Shan Medical University, Taichung, Taiwan
Arch Gen Psychiatry 59:1061-6. 2002..CONCLUSIONS: Prenatal exposure to these compounds produces long-lasting cognitive and behavioral damage, but there is some evidence of recovery... - Exposure assessment for endocrine disruptors: some considerations in the design of studiesCarol Rice
Environmental and Industrial Hygiene Division, University of Cincinnati, Cincinnati, Ohio 45267, USA
Environ Health Perspect 111:1683-90. 2003..A number of issues that must be considered in study design are summarized here... - Pilot studies of estrogen-related physical findings in infantsJudy C Bernbaum
Department of Pediatrics, Children s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Environ Health Perspect 116:416-20. 2008..We wanted to study whether soy formula prolonged the physiologic estrogenization of newborns, but available quantitative descriptions of the natural history of breast and genital development are inadequate for study design... - Duration of breast-feeding and PBBsWalter J Rogan
Environ Health Perspect 110:A503-4; author reply A504. 2002 - Assessment of lead exposure and associated risk factors in urban children in Silesia, PolandDorota Jarosinska
Institute of Occupational Medicine and Environmental Health, 13 Koscielna, 41 200 Sosnowiec, Poland
Environ Res 95:133-42. 2004..Variables found to affect BLL in the Silesian children should be used to propose criteria to improve identification of children at risk and to focus prevention activities more effectively... - Improving behavior of lead-exposed children: micronutrient supplementation, chelation, or preventionAimin Chen
J Pediatr 147:570-1. 2005 - Effect of chelation therapy on the neuropsychological and behavioral development of lead-exposed children after school entryKim N Dietrich
University of Cincinnati College of Medicine, Department of Environmental Health, Cincinnati, Ohio 45267 0056, USA
Pediatrics 114:19-26. 2004..96-2.12 micromol/L) at 12 to 33 months of age has neurodevelopmental benefits at age 7 years...