Stephanie Roessler

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Future of molecular profiling of human hepatocellular carcinoma
    Stephanie Roessler
    National Cancer Institute, Laboratory of Human Carcinogenesis, Center for Cancer Research, NIH, 37 Convent Drive, Bldg 37, Rm 3044A, Bethesda, MD 20892 4258, USA
    Future Oncol 3:429-39. 2007
  2. pmc Integrated metabolite and gene expression profiles identify lipid biomarkers associated with progression of hepatocellular carcinoma and patient outcomes
    Anuradha Budhu
    Liver Carcinogenesis Section, Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA
    Gastroenterology 144:1066-1075.e1. 2013
  3. pmc Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma
    Naoki Oishi
    National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Hepatology 56:1792-803. 2012
  4. pmc Integrative genomic identification of genes on 8p associated with hepatocellular carcinoma progression and patient survival
    Stephanie Roessler
    Laboratory of Human Carcinogenesis, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Gastroenterology 142:957-966.e12. 2012
  5. pmc A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients
    Stephanie Roessler
    Laboratory of Human Carcinogenesis, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Cancer Res 70:10202-12. 2010
  6. pmc Modulation of miR-29 expression by α-fetoprotein is linked to the hepatocellular carcinoma epigenome
    Sonya Parpart
    Laboratory of Human Carcinogenesis, National Cancer Institute, Bethesda, MD Tumor Biology Department, Georgetown University, Washington, DC
    Hepatology 60:872-83. 2014
  7. pmc iSubgraph: integrative genomics for subgroup discovery in hepatocellular carcinoma using graph mining and mixture models
    Bahadir Ozdemir
    Department of Computer Science, University of Maryland, College Park, Maryland, United States of America Liver Carcinogenesis Section, Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America
    PLoS ONE 8:e78624. 2013
  8. pmc Integrative genomic and transcriptomic characterization of matched primary and metastatic liver and colorectal carcinoma
    Stephanie Roessler
    1 Laboratory of Human Carcinogenesis, National Cancer Institute, NIH, Bethesda, MD, USA
    Int J Biol Sci 11:88-98. 2015
  9. pmc MicroRNA expression, survival, and response to interferon in liver cancer
    Junfang Ji
    Liver Carcinogenesis Section, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    N Engl J Med 361:1437-47. 2009

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Future of molecular profiling of human hepatocellular carcinoma
    Stephanie Roessler
    National Cancer Institute, Laboratory of Human Carcinogenesis, Center for Cancer Research, NIH, 37 Convent Drive, Bldg 37, Rm 3044A, Bethesda, MD 20892 4258, USA
    Future Oncol 3:429-39. 2007
    ..Such an approach will provide mechanistic insight into the pathogenesis of HCC, potentially leading to personalized medicine and the identification of new therapeutic targets...
  2. pmc Integrated metabolite and gene expression profiles identify lipid biomarkers associated with progression of hepatocellular carcinoma and patient outcomes
    Anuradha Budhu
    Liver Carcinogenesis Section, Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA
    Gastroenterology 144:1066-1075.e1. 2013
    ..We combined gene expression and metabolic profiling analyses to identify factors associated with outcomes of patients with hepatocellular carcinoma (HCC)...
  3. pmc Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma
    Naoki Oishi
    National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Hepatology 56:1792-803. 2012
    ..NCAM1, a known hepatic stem/progenitor cell marker, was experimentally demonstrated to be a direct target of miR-200c...
  4. pmc Integrative genomic identification of genes on 8p associated with hepatocellular carcinoma progression and patient survival
    Stephanie Roessler
    Laboratory of Human Carcinogenesis, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Gastroenterology 142:957-966.e12. 2012
    ..We used an integrative approach to identify HCC driver genes, defined as genes whose copy numbers associate with gene expression and cancer progression...
  5. pmc A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients
    Stephanie Roessler
    Laboratory of Human Carcinogenesis, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Cancer Res 70:10202-12. 2010
    ....
  6. pmc Modulation of miR-29 expression by α-fetoprotein is linked to the hepatocellular carcinoma epigenome
    Sonya Parpart
    Laboratory of Human Carcinogenesis, National Cancer Institute, Bethesda, MD Tumor Biology Department, Georgetown University, Washington, DC
    Hepatology 60:872-83. 2014
    ..AFP also inhibited transcription of the miR-29a/b-1 locus, and this effect is mediated through c-MYC binding to the transcript of miR-29a/b-1. Furthermore, AFP expression promotes tumor growth of AFP- HCC cells in nude mice...
  7. pmc iSubgraph: integrative genomics for subgroup discovery in hepatocellular carcinoma using graph mining and mixture models
    Bahadir Ozdemir
    Department of Computer Science, University of Maryland, College Park, Maryland, United States of America Liver Carcinogenesis Section, Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America
    PLoS ONE 8:e78624. 2013
    ..iSubgraph is available as MATLAB code at http://www.cs.umd.edu/~ozdemir/isubgraph/. ..
  8. pmc Integrative genomic and transcriptomic characterization of matched primary and metastatic liver and colorectal carcinoma
    Stephanie Roessler
    1 Laboratory of Human Carcinogenesis, National Cancer Institute, NIH, Bethesda, MD, USA
    Int J Biol Sci 11:88-98. 2015
    ..Thus, the metastatic propensity is inherent to the primary tumor and the lack of general metastasis genes necessitates the development of specific treatment modalities. ..
  9. pmc MicroRNA expression, survival, and response to interferon in liver cancer
    Junfang Ji
    Liver Carcinogenesis Section, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    N Engl J Med 361:1437-47. 2009
    ..Hepatocellular carcinoma is a common and aggressive cancer that occurs mainly in men. We examined microRNA expression patterns, survival, and response to interferon alfa in both men and women with the disease...