Research Topics
| Alfred L RocaSummaryAffiliation: National Cancer Institute Country: USA Publications
| Collaborators
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Detail Information
Publications
Initial sequence and comparative analysis of the cat genomeJoan U Pontius
Laboratory of Genomic Diversity, SAIC Frederick, Inc, NCI Frederick, Frederick, Maryland 21702, USA
Genome Res 17:1675-89. 2007..9-fold) coverage mammal genome sequence...
The mastodon mitochondrial genome: a mammoth accomplishmentAlfred L Roca
Department of Animal Sciences, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
Trends Genet 24:49-52. 2008..However, it also suggests that a complex evolutionary picture could ultimately emerge and points to similarities between the early evolution of the Elephantidae and that of the gorilla-human-chimpanzee clade...
Genomic inferences from Afrotheria and the evolution of elephantsAlfred L Roca
Laboratory of Genomic Diversity, Basic Research Program, SAIC Frederick and National Cancer Institute, Frederick, MD 21702, USA
Curr Opin Genet Dev 15:652-9. 2005..The elephant genome sequence might prove useful for comparative genomic studies of these advanced traits, which have appeared independently in only three mammalian orders: primates, cetaceans and proboscideans...
Mesozoic origin for West Indian insectivoresAlfred L Roca
Laboratory of Genomic Diversity, Basic Research Program, SAIC Frederick, National Cancer Institute, Frederick, Maryland 21702, USA
Nature 429:649-51. 2004..Efforts to prevent extinction of the two surviving solenodon species would conserve an entire lineage as old or older than many mammalian orders...
Insertional polymorphisms of endogenous feline leukemia virusesAlfred L Roca
Laboratory of Genomic Diversity, Basic Research Program, SAIC Frederick, Maryland, USA
J Virol 79:3979-86. 2005..Since endogenous FeLVs may affect the infectiousness or pathogenicity of exogenous FeLVs, genomic variation in enFeLVs represents a candidate for genetic influences on FeLV leukemogenesis in cats...
Genetic characterization of feline leukemia virus from Florida panthersMeredith A Brown
National Cancer Institute, Frederick, Maryland, USA
Emerg Infect Dis 14:252-9. 2008..These unique features may also account for the severity of the outbreak after cross-species transmission to the panther...
Genomically intact endogenous feline leukemia viruses of recent originAlfred L Roca
Laboratory of Genomic Diversity, Basic Research Program, SAIC-Frederick, Maryland 21702, USA
J Virol 78:4370-5. 2004....
The Near Eastern origin of cat domesticationCarlos A Driscoll
Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702, USA
Science 317:519-23. 2007..Domestic cats derive from at least five founders from across this region, whose descendants were transported across the world by human assistance...
Pathological manifestations of feline immunodeficiency virus (FIV) infection in wild African lionsMelody E Roelke
Laboratory of Genomic Diversity, SAIC Frederick, Inc, NCI Frederick, Frederick, MD, USA
Virology 390:1-12. 2009....
Mitochondrial phylogeography illuminates the origin of the extinct caspian tiger and its relationship to the amur tigerCarlos A Driscoll
Wildlife Conservation Research Unit, Department of Zoology, University of Oxford, Tubney, Oxon, United Kingdom
PLoS ONE 4:e4125. 2009..Also, due to their evolutionary propinquity, living Amur tigers offer an appropriate genetic source should reintroductions to the former range of the Caspian tiger be implemented...
Cytonuclear genomic dissociation in African elephant speciesAlfred L Roca
Laboratory of Genomic Diversity, Basic Research Program, SAIC-Frederick, Frederick, Maryland 21702, USA
Nat Genet 37:96-100. 2005..The persistence of residual forest elephant mitochondria in savanna elephant herds renders evolutionary interpretations based on mitochondrial DNA alone misleading and preserves a genomic record of ancient habitat changes...
A nuclear DNA phylogeny of the woolly mammoth (Mammuthus primigenius)Cristian Capelli
Istituto di Medicina Legale, , Rome, Italy
Mol Phylogenet Evol 40:620-7. 2006
Patterns of molecular genetic variation among African elephant populationsKenine E Comstock
Clinical Research Division, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, D4-100, Seattle, WA 98109-1024, USA
Mol Ecol 11:2489-98. 2002..The savannah elephants show significantly lower genetic diversity than forest elephants, probably reflecting a founder effect in the recent history of the savannah species...
