Robin Roberson

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. doi request reprint Neuroprotective peptides influence cytokine and chemokine alterations in a model of fetal alcohol syndrome
    Robin Roberson
    Unit on Perinatal and Developmental Neurobiology, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    Am J Obstet Gynecol 207:499.e1-5. 2012
  2. doi request reprint Cytokine and chemokine alterations in Down syndrome
    Robin Roberson
    Unit on Perinatal and Developmental Neurobiology, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    Am J Perinatol 29:705-8. 2012
  3. pmc Responses to S. Leonard Syme's essay
    Robert G Robinson
    Prev Chronic Dis 1:A13. 2004
  4. pmc Neuroprotective fractalkine in fetal alcohol syndrome
    Robin Roberson
    Unit on Perinatal and Developmental Neurobiology, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    Am J Obstet Gynecol 204:400.e1-3. 2011
  5. pmc Alterations in phosphorylated cyclic adenosine monophosphate response element of binding protein activity: a pathway for fetal alcohol syndrome-related neurotoxicity
    Robin Roberson
    Unit on Perinatal and Developmental Neurobiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20895, USA
    Am J Obstet Gynecol 200:193.e1-5. 2009
  6. pmc Altered expression of KIF17, a kinesin motor protein associated with NR2B trafficking, may mediate learning deficits in a Down syndrome mouse model
    Robin Roberson
    Unit on Perinatal and Developmental Neurobiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20895, USA
    Am J Obstet Gynecol 198:313.e1-4. 2008
  7. doi request reprint Reversal of alcohol-induced learning deficits in the young adult in a model of fetal alcohol syndrome
    Maddalena Incerti
    Unit on Perinatal and Developmental Neurobiology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 0925, USA
    Obstet Gynecol 115:350-6. 2010
  8. doi request reprint Prenatal NAP+SAL prevents developmental delay in a mouse model of Down syndrome through effects on N-methyl-D-aspartic acid and gamma-aminobutyric acid receptors
    Joy Vink
    Unit on Perinatal and Developmental Neurobiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    Am J Obstet Gynecol 200:524.e1-4. 2009
  9. pmc Prevention of developmental delays in a Down syndrome mouse model
    Laura Toso
    Unit on Perinatal and Developmental Neurobiology, Eunice Kennedy Shriver National Institute of Child and Human Development, National Institutes of Health, Bethesda, Maryland 20852, USA
    Obstet Gynecol 112:1242-51. 2008
  10. ncbi request reprint Postnatal inflammatory rat model for cerebral palsy: too different from humans
    Robin Roberson
    Unit on Perinatal and Developmental Neurobiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    Am J Obstet Gynecol 195:1038-44. 2006

Collaborators

Detail Information

Publications21

  1. doi request reprint Neuroprotective peptides influence cytokine and chemokine alterations in a model of fetal alcohol syndrome
    Robin Roberson
    Unit on Perinatal and Developmental Neurobiology, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    Am J Obstet Gynecol 207:499.e1-5. 2012
    ..We evaluated a panel of cytokines and chemokines to determine whether NAP plus SAL work through a cytokine/chemokine-mediated pathway in preventing these alterations...
  2. doi request reprint Cytokine and chemokine alterations in Down syndrome
    Robin Roberson
    Unit on Perinatal and Developmental Neurobiology, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    Am J Perinatol 29:705-8. 2012
    ..The objective of this study was to evaluate if cytokines and chemokines in the hippocampus and cerebellum are altered in this model...
  3. pmc Responses to S. Leonard Syme's essay
    Robert G Robinson
    Prev Chronic Dis 1:A13. 2004
  4. pmc Neuroprotective fractalkine in fetal alcohol syndrome
    Robin Roberson
    Unit on Perinatal and Developmental Neurobiology, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    Am J Obstet Gynecol 204:400.e1-3. 2011
    ..Fractalkine, a chemokine constitutively expressed in the CNS reduces neuronal death from activated microglia. Using a model of FAS we evaluated if fractalkine is altered and if NAP+SAL work through fractalkine...
  5. pmc Alterations in phosphorylated cyclic adenosine monophosphate response element of binding protein activity: a pathway for fetal alcohol syndrome-related neurotoxicity
    Robin Roberson
    Unit on Perinatal and Developmental Neurobiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20895, USA
    Am J Obstet Gynecol 200:193.e1-5. 2009
    ..In adult (FAS) mice, we measured phosphorylated cyclic adenosine monophosphate response element of binding protein (pCREB) staining in hippocampal subregions to evaluate a possible mechanism underlying FAS learning deficits...
  6. pmc Altered expression of KIF17, a kinesin motor protein associated with NR2B trafficking, may mediate learning deficits in a Down syndrome mouse model
    Robin Roberson
    Unit on Perinatal and Developmental Neurobiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20895, USA
    Am J Obstet Gynecol 198:313.e1-4. 2008
    ..Down regulation of KIF17 reflects up-regulation of less plastic NR2A subunit. We evaluated NR2B, NR2A, and KIF17 in Ts65Dn and control mice...
  7. doi request reprint Reversal of alcohol-induced learning deficits in the young adult in a model of fetal alcohol syndrome
    Maddalena Incerti
    Unit on Perinatal and Developmental Neurobiology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 0925, USA
    Obstet Gynecol 115:350-6. 2010
    ....
  8. doi request reprint Prenatal NAP+SAL prevents developmental delay in a mouse model of Down syndrome through effects on N-methyl-D-aspartic acid and gamma-aminobutyric acid receptors
    Joy Vink
    Unit on Perinatal and Developmental Neurobiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    Am J Obstet Gynecol 200:524.e1-4. 2009
    ..We investigated whether this finding involves N-methyl-D-aspartic acid and gamma-aminobutyric acid (GABA) receptor subunits...
  9. pmc Prevention of developmental delays in a Down syndrome mouse model
    Laura Toso
    Unit on Perinatal and Developmental Neurobiology, Eunice Kennedy Shriver National Institute of Child and Human Development, National Institutes of Health, Bethesda, Maryland 20852, USA
    Obstet Gynecol 112:1242-51. 2008
    ....
  10. ncbi request reprint Postnatal inflammatory rat model for cerebral palsy: too different from humans
    Robin Roberson
    Unit on Perinatal and Developmental Neurobiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    Am J Obstet Gynecol 195:1038-44. 2006
    ..We studied a postnatal CP model to evaluate injury that would correlate with presence of Pre-OL in human pregnancy...
  11. pmc Prenatal treatment prevents learning deficit in Down syndrome model
    Maddalena Incerti
    Unit on Perinatal and Developmental Neurobiology, National Institute of Child and Human Development, Bethesda, Maryland, United States of America
    PLoS ONE 7:e50724. 2012
    ..These findings highlight a possibility for the prevention of sequelae in Down syndrome and suggest a potential pregnancy intervention that may improve outcome...
  12. doi request reprint Treatment with neuropeptides attenuates c-fos expression in a mouse model of fetal alcohol syndrome
    Maddalena Incerti
    Unit on Perinatal and Developmental Neurobiology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Health, Bethesda, Maryland 20892 0925, USA
    Am J Perinatol 27:743-8. 2010
    ..There was no difference in C-FOS expression in the cortex. Adult treatment with NAP + SAL restored the down-regulation of C-FOS expression in hippocampus attenuating the alcohol-induced alteration of the stress-signal pathway...
  13. ncbi request reprint Prevention of alcohol-induced learning deficits in fetal alcohol syndrome mediated through NMDA and GABA receptors
    Laura Toso
    Unit on Perinatal and Developmental Neurobiology, National Institute of Child and Human Development, National Institutes of Health, Bethesda, MD 20892 0925, USA
    Am J Obstet Gynecol 194:681-6. 2006
    ..Vasoactive intestinal peptide (VIP)-related peptides prevented the learning deficit in the offspring in a model for fetal alcohol syndrome. We evaluated whether the mechanism of the peptide protection included NR2B, NR2A, and GABAAalpha5...
  14. doi request reprint Prevention of the alcohol-induced changes in brain-derived neurotrophic factor expression using neuroprotective peptides in a model of fetal alcohol syndrome
    Maddalena Incerti
    Unit on Perinatal and Developmental Neurobiology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Health, Bethesda, MD, USA
    Am J Obstet Gynecol 202:457.e1-4. 2010
    ....
  15. ncbi request reprint Prenatal alcohol exposure alters GABA(A)alpha5 expression: a mechanism of alcohol-induced learning dysfunction
    Laura Toso
    Unit on Perinatal and Developmental Neurobiology, National Institute of Child and Human Development, National Institute of Health, Bethesda, MD 20892 0925, USA
    Am J Obstet Gynecol 195:522-7. 2006
    ..We were interested to evaluate alcohol's effect on GABA(A)alpha5 expression to further understand alcohol-induced learning dysfunction...
  16. ncbi request reprint Neuroprotective peptides prevent some alcohol-induced alteration in gamma-aminobutyric acid A-beta3, which plays a role in cleft lip and palate and learning in fetal alcohol syndrome
    Laura Toso
    Unit on Perinatal and Developmental Neurobiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    Am J Obstet Gynecol 196:259.e1-5. 2007
    ..The gamma-aminobutyric acid A (GABA) receptor subunit GABAbeta3 plays a critical role for nervous system and palate development. Our objective was to determine whether the neuropeptides prevented alcohol-induced damage through GABAbeta3...
  17. ncbi request reprint N-methyl-D-aspartate subunit expression during mouse development altered by in utero alcohol exposure
    Laura Toso
    NICHD, National Institutes of Health, Bethesda, MD 20892 0925, USA
    Am J Obstet Gynecol 193:1534-9. 2005
    ..To understand the mechanism of learning deficits in FAS, we evaluated NR2B and NR2A expression in embryonic and adult mice...
  18. ncbi request reprint Inflammatory-mediated model of cerebral palsy with developmental sequelae
    Laura Toso
    Unit on Perinatal and Developmental Neurobiology, National Institute of Child and Human Development National Institute of Health, Bethesda, MD 20892 0925, USA
    Am J Obstet Gynecol 193:933-41. 2005
    ..Our objective was to develop an inflammatory model for CP based on chronic lipopolysaccharide (LPS) exposure with a recognizable phenotype in offspring...
  19. pmc Understanding the mechanism of learning enhancement: NMDA and GABA receptor expression
    Laura Toso
    Unit on Perinatal and Developmental Neurobiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    Am J Obstet Gynecol 197:267.e1-4. 2007
    ..Our objective was to test whether NMDA and GABA receptors contribute to the learning enhancement that is induced by the peptides after adult administration...
  20. doi request reprint Prevention of learning deficit in a Down syndrome model
    Maddalena Incerti
    From the Unit on Perinatal and Developmental Neurobiology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Health, Bethesda, MD 20892 0925, USA
    Obstet Gynecol 117:354-61. 2011
    ..To evaluate whether peptides given to adult mice with Down syndrome prevent learning deficits, and to delineate the mechanisms behind the protective effect...
  21. ncbi request reprint No phenotype associated with established lipopolysaccharide model for cerebral palsy
    Sarah H Poggi
    Unit on Perinatal and Developmental Neurobiology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    Am J Obstet Gynecol 192:727-33. 2005
    ..To evaluate whether this histologic end point is associated with a CP phenotype, we reproduced a lipopolysaccharide (LPS) model for PVL, 1 and evaluated developmental, behavioral, and motor outcomes...