Research Topics
| Brendan A RichSummaryAffiliation: National Institutes of Health Country: USA Publications
| Collaborators
|
Detail Information
Publications
An investigation of prepulse inhibition in pediatric bipolar disorderBrendan A Rich
Pediatrics and Developmental Neuropsychiatry Branch, Unit on Affective Psychophysiology, Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 1255, USA
Bipolar Disord 7:198-203. 2005..Sensorimotor gating deficits may contribute to the emotional and behavioral dysregulation characteristic of pediatric BPD. The current study investigated possible PPI deficits in children with BPD...- The impact of reward, punishment, and frustration on attention in pediatric bipolar disorderBrendan A Rich
Pediatrics and Developmental Neuropsychiatry Branch, Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 1255, USA
Biol Psychiatry 58:532-9. 2005..We tested the hypothesis that frustration adversely impacts attention and behavior in children with bipolar disorder (BPD)... - Using affect-modulated startle to study phenotypes of pediatric bipolar disorderBrendan A Rich
Pediatrics and Developmental Neuropsychiatry Branch, Department of Health and Human Services, National Institutes of Health, Bethesda, MD 20892, USA
Bipolar Disord 7:536-45. 2005..The current study used affect-modulated startle to examine potential differences in reactivity to emotional stimuli (reward and punishment) in narrow and broad phenotype PBD and controls... - Face emotion labeling deficits in children with bipolar disorder and severe mood dysregulationBrendan A Rich
National Institute of Mental Health, National Institutes of Health, Building 15K, Room 204, MSC2670, Bethesda, MD 20892 2670, USA
Dev Psychopathol 20:529-46. 2008..These deficits are associated with psychosocial impairments. Understanding the neural circuitry associated with face-labeling deficits has the potential to clarify the pathophysiology of these disorders... - Neural connectivity in children with bipolar disorder: impairment in the face emotion processing circuitBrendan A Rich
Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda 20892 2670, MD, USA
J Child Psychol Psychiatry 49:88-96. 2008.... - Different psychophysiological and behavioral responses elicited by frustration in pediatric bipolar disorder and severe mood dysregulationBrendan A Rich
Pediatrics and Developmental Neuropsychiatry Branch, Section on Development and Affective Neuroscience, NIMH Mood and Anxiety Program, Bethesda, MD 20892, USA
Am J Psychiatry 164:309-17. 2007..e., a history of at least one manic or hypomanic episode with euphoric mood) as well as those with no diagnosis (i.e., healthy comparison children)... - Brain systems underlying response flexibility in healthy and bipolar adolescents: an event-related fMRI studyEric E Nelson
Mood and Anxiety Disorders Program, National Institute of Mental Health, Building 106 C, 5413 W Cedar Lane, Bethesda, MD 20892, USA
Bipolar Disord 9:810-9. 2007..The present study was undertaken to determine if neuronal responses differed between BD and control subjects on a simple motor response flexibility task... - Amygdala activation during emotion processing of neutral faces in children with severe mood dysregulation versus ADHD or bipolar disorderMelissa A Brotman
Emotion and Development Branch, Mood and Anxiety Disorders Program, NIMH, NIH, Department of Health and Human Services, Bethesda, MD 20892, USA
Am J Psychiatry 167:61-9. 2010..The authors compared amygdala response during emotional and nonemotional ratings of neutral faces in youths with these disorders as well as a group of healthy comparison youths... - Facial emotion labeling deficits in children and adolescents at risk for bipolar disorderMelissa A Brotman
Mood and Anxiety Disorders Program, NIMH, NIH, Bethesda, MD 20892, USA
Am J Psychiatry 165:385-9. 2008.... - Neural activation during encoding of emotional faces in pediatric bipolar disorderDaniel P Dickstein
Division of Intramural Research Program, National Institute of Mental Health, Pediatrics and Developmental Neuropsychiatry Branch, Bethesda, MD 20892 2670, USA
Bipolar Disord 9:679-92. 2007..To begin to address these limitations, the current study tests the hypothesis that pediatric BD (PBD) subjects exhibit altered neural activation during encoding of emotional faces compared to typically developing controls... - Parental diagnoses in youth with narrow phenotype bipolar disorder or severe mood dysregulationMelissa A Brotman
Emotion and Development Branch and the Genetic Basis of Mood and Anxiety Disorders Unit, Mood and Anxiety Disorders Program, NIMH, NIH, Department of Health and Human Services, Bethesda, MD 20892, USA
Am J Psychiatry 164:1238-41. 2007..The authors compared axis I diagnoses in parents of children with narrow phenotype bipolar disorder and parents of youth with severe mood dysregulation... - Cognitive flexibility in phenotypes of pediatric bipolar disorderDaniel P Dickstein
National Institute of Mental Health, Pediatrics and Developmental Neuropsychiatry Branch, 9000 Rockville Pike, MSC 2670 Building 15K Room 204, Bethesda MD 20892 2670, USA
J Am Acad Child Adolesc Psychiatry 46:341-55. 2007..6 +/- 2.4 years). Cognitive flexibility is relevant to symptoms of BD involving dysfunctional reward systems (e.g., excessive goal-directed activity and pleasure-seeking in mania; anhedonia in depression)... - Neural circuitry engaged during unsuccessful motor inhibition in pediatric bipolar disorderEllen Leibenluft
Emotion and Development Branch, Mood and Anxiety Disorders Program, NIMH, NIH, Health and Human Services, Bldg 15k, MSC 2670, Bethesda, MD 20892 2670, USA
Am J Psychiatry 164:52-60. 2007..They also compared activation in medicated versus unmedicated children with bipolar disorder and in children with bipolar disorder and attention deficit hyperactivity disorder (ADHD) versus those with bipolar disorder without ADHD... - Specificity of facial expression labeling deficits in childhood psychopathologyAmanda E Guyer
Mood and Anxiety Program MAP, National Institute of Mental Health NIMH, National Institutes of Health NIH, Department of Health and Human Services DHHS, Bethesda, MD, USA
J Child Psychol Psychiatry 48:863-71. 2007..We examined whether face-emotion labeling deficits are illness-specific or an epiphenomenon of generalized impairment in pediatric psychiatric disorders involving mood and behavioral dysregulation... - Attention bias to threat faces in children with bipolar disorder and comorbid lifetime anxiety disordersMelissa A Brotman
Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Biol Psychiatry 61:819-21. 2007..Although comorbid anxiety disorders are common in children with bipolar disorder (BD), it is unclear how this comorbidity impacts the pathophysiology of the illness... - Risk for bipolar disorder is associated with face-processing deficits across emotionsMelissa A Brotman
National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
J Am Acad Child Adolesc Psychiatry 47:1455-61. 2008..It is unclear whether this deficit in at-risk youths is present across all emotions or if the impairment presents initially as an emotion-specific dysfunction that then generalizes to other emotions as the symptoms of BD become manifest... - Limbic hyperactivation during processing of neutral facial expressions in children with bipolar disorderBrendan A Rich
Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 2670, USA
Proc Natl Acad Sci U S A 103:8900-5. 2006..Results implicate deficient emotion-attention interactions in the pathophysiology of BD in youth and suggest that developmental psychobiology approaches to chronic mental illness have broad applicability... - Prevalence, clinical correlates, and longitudinal course of severe mood dysregulation in childrenMelissa A Brotman
Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
Biol Psychiatry 60:991-7. 2006..This syndrome has been called the "broad BD phenotype" or severe mood dysregulation (SMD). This study examines prevalence, concurrent Axis I diagnoses, and longitudinal outcome of SMD in an epidemiologic sample... - Comorbid anxiety in phenotypes of pediatric bipolar disorderDaniel P Dickstein
Mood and Anxiety Disorders Program, Pediatrics and Developmental Neuropsychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892 1255, USA
J Child Adolesc Psychopharmacol 15:534-48. 2005..Adult BPD studies suggest comorbid anxiety disorders are common and impact treatment outcome. We explored the association of comorbid anxiety with two phenotypes of pediatric BPD... - Pediatric bipolar disorderEllen Leibenluft
Section on Bipolar Spectrum Disorders, Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda MD, USA
Annu Rev Clin Psychol 4:163-87. 2008..Throughout the review, we pay particular attention to youths with severe chronic irritability, hyperarousal, and hyperreactivity, who reflect the population in whom the diagnosis of BD is most debated... - Perception of facial emotion in adults with bipolar or unipolar depression and controlsKathryn L Schaefer
Department of Counseling and Personnel Services, University of Maryland, College Park, MD, USA
J Psychiatr Res 44:1229-35. 2010..Groups were compared in terms of sensitivity and accuracy in identifying emotions. Our preliminary findings suggest that subjects with bipolar depression may have emotional processing abnormalities relative to controls...