Research Topics
| S M ResnickSummaryAffiliation: National Institutes of Health Country: USA Publications
| Collaborators
|
Detail Information
Publications
One-year age changes in MRI brain volumes in older adultsS M Resnick
Laboratory of Personality and Cognition, National Institute on Aging, Baltimore, MD 21224 6825, USA
Cereb Cortex 10:464-72. 2000..Definition of the pattern and rate of longitudinal brain changes will facilitate the detection of pathological brain changes, which may be predictors of dementia...
The relationship between longitudinal declines in dehydroepiandrosterone sulfate concentrations and cognitive performance in older menS D Moffat
Laboratory of Personality and Cognition, National Institute on Aging, 5600 Nathan Shock Dr, Baltimore, MD 21224, USA
Arch Intern Med 160:2193-8. 2000..In the United States, DHEA is widely available as an over-the-counter supplement that individuals are using in an effort to ameliorate age-related cognitive and physical changes...
Longitudinal effects of estrogen replacement therapy on PET cerebral blood flow and cognitionP M Maki
Laboratory of Personality and Cognition, Gerontology Research Center, NIA NIH, Box 3, 5600 Nathan Shock Drive, Baltimore, MD 21224, USA
Neurobiol Aging 21:373-83. 2000..Group differences in longitudinal change in rCBF patterns may reflect one way through which hormones modulate brain activity and contribute to enhanced memory performance among ERT users...
Enhanced verbal memory in nondemented elderly women receiving hormone-replacement therapyP M Maki
Laboratory of Personality and Cognition, Gerontology Research Center, Baltimore, MD 21224, USA
Am J Psychiatry 158:227-33. 2001..This study examined the effects of hormone-replacement therapy on memory and other cognitive abilities in cognitively intact older women...
I. Longitudinal changes in aging brain functionL L Beason-Held
Laboratory of Personality and Cognition, National Institute on Aging, NIH, NIA LPC, 5600 Nathan Shock Drive, Baltimore, MD 21224 6825, USA
Neurobiol Aging 29:483-96. 2008..In view of the stable memory performance, the task-dependent results suggest that age-related changes in brain activity help maintain cognitive function with advancing age...
Verbal and figural recognition memory: task development and age associationsS Golski
Laboratory of Personality and Cognition, Gerontology Research Center, National Institutes on Aging, Baltimore, Maryland 21224 6825, USA
Exp Aging Res 24:359-85. 1998....
Longitudinal pattern of regional brain volume change differentiates normal aging from MCII Driscoll
Laboratory of Personality and Cognition, National Institute on Aging, Baltimore, MD 21224, USA
Neurology 72:1906-13. 2009..We predict that the regions that show early pathologic changes in association with Alzheimer disease will show accelerated volume loss in mild cognitive impairment (MCI) compared to normal aging...
Postmenopausal hormone therapy and regional brain volumes: the WHIMS-MRI StudyS M Resnick
Laboratory of Personality and Cognition, Biomedical Research Center 04B317, Baltimore, MD 21224, USA
Neurology 72:135-42. 2009..To determine whether menopausal hormone therapy (HT) affects regional brain volumes, including hippocampal and frontal regions...
Free testosterone and risk for Alzheimer disease in older menS D Moffat
Laboratory of Personality and Cognition, National Institute on Aging, Intramural Research Program, Baltimore, MD 21224, USA
Neurology 62:188-93. 2004..Future research may determine whether higher endogenous free testosterone levels offer protection against a diagnosis of Alzheimer disease in older men...
Effects of hormone replacement therapy on cognitive and brain agingS M Resnick
Laboratory of Personality and Cognition, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, USA
Ann N Y Acad Sci 949:203-14. 2001....
Longitudinal cognitive decline is associated with fibrillar amyloid-beta measured by [11C]PiBS M Resnick
Laboratory of Personality and Cognition, National Institute on Aging, 251 Bayview Blvd BRC Room 4B335, Baltimore, MD 21224 6825, USA
Neurology 74:807-15. 2010..To investigate whether longitudinal declines in cognition are associated with higher fibrillar amyloid-beta (Abeta) deposition in vivo in individuals without dementia...
In vivo human amyloid imagingJ Sojkova
Laboratory of Personality and Cognition, NIH Biomedical Research Center, National Institute on Aging, IRP, Baltimore, MD 21224, USA
Curr Alzheimer Res 8:366-72. 2011....
II. Temporal patterns of longitudinal change in aging brain functionL L Beason-Held
Laboratory of Personality and Cognition, National Institute on Aging, NIH, 5600 Nathan Shock Drive, Baltimore, MD 21224 6825, USA
Neurobiol Aging 29:497-513. 2008..The precise patterns of regional involvement and the temporal dynamics of rCBF change within specific regions vary based on cognitive processing demands...
Effect of a clinical stroke on the risk of dementia in a prospective cohortA Gamaldo
Department of Neurology, Johns Hopkins University, Baltimore, MD, USA
Neurology 67:1363-9. 2006..Pathologic data indicate that both vascular and Alzheimer pathology leads to the prestroke impairment. CONCLUSION: Dementia after stroke may be determined by cognitive impairments that exist prior to the stroke...
Brain activation during encoding and recognition of verbal and figural information in older adultsL L Beason-Held
Laboratory of Personality and Cognition, National Institute on Aging, NIH, NIA LPC, 5600 Nathan Shock Drive, Baltimore, MD 21224 6825, USA
Neurobiol Aging 26:237-50. 2005....
Voxel-based morphometry using the RAVENS maps: methods and validation using simulated longitudinal atrophyC Davatzikos
Center for Biomedical Image Computing, Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Neuroimage 14:1361-9. 2001..Improved sensitivity was achieved at the expense of human effort involved in defining a number of sulcal curves that serve as constraints on the 3D elastic warping...
No advantage of A beta 42-lowering NSAIDs for prevention of Alzheimer dementia in six pooled cohort studiesC A Szekely
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Neurology 70:2291-8. 2008..One hypothesis holds that the subset of NSAIDs known as selective A beta(42)-lowering agents (SALAs) is responsible for this apparent reduction in AD risk...
Visual memory predicts Alzheimer's disease more than a decade before diagnosisC H Kawas
Alzheimer s Disease Research Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Neurology 60:1089-93. 2003....
Age differences in spatial memory in a virtual environment navigation taskS D Moffat
Gerontology Research Center, National Institute on Aging, 5600 Nathan Shock Drive, Baltimore MD 21224, USA
Neurobiol Aging 22:787-96. 2001..Performance on the VE navigation task was positively correlated with measures of mental rotation and verbal and visual memory...
Accuracy and sensitivity of detection of activation foci in the brain via statistical parametric mapping: a study using a PET simulatorC Davatzikos
Department of Radiology, Johns Hopkins University School of Medicine, 601 North Caroline Street, Baltimore, Maryland, 21287, USA
Neuroimage 13:176-84. 2001..The results indicate some limitations of statistical parametric mapping, assist in the correct interpretation of the SPM maps, and point to future research directions in functional image analysis...
Effects of estrogen on patterns of brain activity at rest and during cognitive activity: a review of neuroimaging studiesP M Maki
Gerontology Research Center, National Institute on Aging, 5600 Nathan Shock Drive, Baltimore, Maryland 21231, USA
Neuroimage 14:789-801. 2001..General procedural guidelines for controlling and investigating hormone effects in neuroimaging studies are discussed...
Individual patient diagnosis of AD and FTD via high-dimensional pattern classification of MRIC Davatzikos
Section of Biomedical Image Analysis, Department of Radiology, University of Pennsylvania, 3600 Market Street, Suite 380, Philadelphia, PA 19104, USA
Neuroimage 41:1220-7. 2008..In conclusion, AD- and FTD-specific patterns of brain atrophy can be detected with high accuracy using high-dimensional pattern classification of MRI scans obtained in a typical clinical setting...
