Research Topics
| Jennifer S ReadSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Safety of HIV-1 Perinatal Transmission Prophylaxis With Zidovudine and Nevirapine in Rural South IndiaJennifer S Read
Pediatric, Adolescent, and Maternal AIDS Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland
J Int Assoc Physicians AIDS Care (Chic) 6:125-36. 2007..Background: The authors assessed acceptance and safety of, and adherence to, perinatal HIV-1 transmission prophylaxis at 2 public hospitals in rural Tamil Nadu, India...
Human immunodeficiency virus diagnostic testing of infants at clinical sites in North America: 2002-2006Jennifer S Read
Pediatric, Adolescent, and Maternal AIDS Branch, CRMC, NICHD, National Institutes of Health, DHHS, Bethesda, MD 20892 7510, USA
Pediatr Infect Dis J 28:614-8. 2009....
Management of human immunodeficiency virus-infected pregnant women at Latin American and Caribbean sitesJennifer S Read
National Institute of Child Health and Human Development, Bethesda, Maryland, USA
Obstet Gynecol 109:1358-67. 2007....
Pharmacokinetics of new 625 mg nelfinavir formulation during pregnancy and postpartumJ S Read
Pediatric, Adolescent and Maternal AIDS Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 7510, USA
HIV Med 9:875-82. 2008..Our objective was to evaluate the pharmacokinetics of nelfinavir (NFV) (625 mg tablets) 1250 mg twice daily during pregnancy and postpartum...
Primary HIV-1 infection among infants in sub-Saharan Africa: HPTN 024Jennifer S Read
Pediatric, Adolescent, and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 7510, USA
J Acquir Immune Defic Syndr 51:317-22. 2009..Our objectives were to assess clinical signs and diagnoses associated with primary HIV-1 infection among infants...
Infants of human immunodeficiency virus type 1-infected women in rural south India: feeding patterns and risk of mother-to-child transmissionJennifer S Read
Pediatric, Adolescent, and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health Executive Building, Room 4B11C, 6100 Executive Boulevard MSC 7510, Bethesda, MD 20892 7510
Pediatr Infect Dis J 29:14-7. 2010..We assessed the infant feeding choices of HIV-1-infected women in rural Tamil Nadu, India, and risk factors for mother-to-child transmission of HIV-1...
Prevention of mother-to-child transmission of HIV: antiretroviral strategiesJennifer S Read
Pediatric, Adolescent, and Maternal AIDS Branch, Center for Research for Mothers and Children, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, 6100 Executive Boulevard, Bethesda, MD 20892 7510, USA
Clin Perinatol 37:765-76, viii. 2010..Antiretroviral strategies to prevent antepartum, intrapartum, and early postnatal transmission in resource-poor settings are also addressed, albeit more briefly...
CD4+ lymphocyte-based immunologic outcomes of perinatally HIV-infected children during antiretroviral therapy interruptionGeorge K Siberry
Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
J Acquir Immune Defic Syndr 57:223-9. 2011..To assess the characteristics and outcomes of antiretroviral treatment (ART) interruption (TI) in perinatally HIV-infected children...
Missed opportunities for prevention of mother-to-child transmission of HIV-1 in the NISDI Perinatal and LILAC cohortsJennifer S Read
Pediatric, Adolescent, and Maternal AIDS Branch, CRMC, NICHD, NIH, DHHS, Bethesda, USA
Int J Gynaecol Obstet 119:70-5. 2012..To evaluate cases of mother-to-child transmission of HIV-1 at multiple sites in Latin America and the Caribbean in terms of missed opportunities for prevention...
Guidelines for the Prevention and Treatment of Opportunistic Infections among HIV-exposed and HIV-infected children: recommendations from CDC, the National Institutes of Health, the HIV Medicine Association of the Infectious Diseases Society of America, tLynne M Mofenson
National Institutes of Health, Bethesda, Maryland, USA
MMWR Recomm Rep 58:1-166. 2009..nih.gov...
Phase I/II, open-label trial of safety and immunogenicity of meningococcal (groups A, C, Y, and W-135) polysaccharide diphtheria toxoid conjugate vaccine in human immunodeficiency virus-infected adolescentsGeorge K Siberry
Pediatric, Adolescent, and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD 20892 7510, USA
Pediatr Infect Dis J 29:391-6. 2010..Quadrivalent meningococcal polysaccharide conjugate vaccine (MCV4) is routinely recommended for healthy youth in the United States, but there are no data about its use in HIV-infected people...
Prevention of mother-to-child transmission of HIV through breast milkJennifer S Read
Pediatric, Adolescent, and Maternal AIDS Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
Pediatr Infect Dis J 27:649-50. 2008
Maternal antiretrovirals and hepatic enzyme, hematologic abnormalities among human immunodeficiency virus type 1-uninfected infants: the NISDI perinatal studyMarisa M Mussi-Pinhata
Department of Pediatrics, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil
Pediatr Infect Dis J 26:1032-7. 2007..To assess hepatic enzyme (HE) and hematologic abnormalities among human immunodeficiency virus-1-uninfected infants according to maternal antiretroviral regimen during pregnancy...
Predictors of stillbirth in sub-saharan AfricaBenjamin H Chi
Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
Obstet Gynecol 110:989-97. 2007..To describe the incidence and predictors of stillbirth in a predominantly human immunodeficiency virus (HIV)-infected African cohort...
Cesarean delivery for HIV-infected women: recommendations and controversiesDenise J Jamieson
Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Am J Obstet Gynecol 197:S96-100. 2007..However, a number of important questions remain unanswered, including whether cesarean delivery has a role among HIV-infected women with low plasma viral loads or who receive combination antiretroviral regimens...
Missed opportunities for prevention of mother-to-child transmission of human immunodeficiency virus type 1 in Latin America and the Caribbean: the NISDI perinatal studyJennifer S Read
Hospital dos Servidores do Estado, Rio de Janeiro, Brazil
Pediatr Infect Dis J 26:649-53. 2007..98% (95% CI = 0.45-1.96%)]. Five cases (62%) represented missed opportunities for prevention of MTCT of HIV-1, suggesting the need for ongoing training and education of clinicians regarding prevention of MTCT of HIV-1...
Risk factors for late postnatal transmission of human immunodeficiency virus type 1 in sub-Saharan AfricaCharles Chasela
University of North Carolina Project, Kamuzu Central Hospital, Lilongwe, Malawi
Pediatr Infect Dis J 27:251-6. 2008..We conducted secondary data analyses of a clinical trial (HIVNET 024) to assess risk factors for late postnatal transmission (LPT) of human immunodeficiency virus type 1 (HIV-1) through breast-feeding...
Laboratory abnormalities among HIV-1-infected pregnant women receiving antiretrovirals in Latin America and the CaribbeanMariana Ceriotto
Hospital Cecilia Grierson, Buenos Aires, Argentina
AIDS Patient Care STDS 22:167-71. 2008
Antiretroviral resistance among HIV type 1-infected women first exposed to antiretrovirals during pregnancy: plasma versus PBMCsLuis E Soto-Ramirez
Department of Infectious Diseases, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico, DF, Mexico
AIDS Res Hum Retroviruses 24:797-804. 2008..The prevalence of RAMs among these pregnant, HIV-1-infected women is high (15%). Rates of detection of RAMs in plasma and PBMC samples were similar...
Nutritional indicators of adverse pregnancy outcomes and mother-to-child transmission of HIV among HIV-infected womenSaurabh Mehta
Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
Am J Clin Nutr 87:1639-49. 2008..Poor nutrition may be associated with mother-to-child transmission (MTCT) of HIV and other adverse pregnancy outcomes...
Adherence to antiretrovirals among US women during and after pregnancyArlene D Bardeguez
Department of Obstetrics, Gynecology and Women s Health, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, NJ 07103 1709, USA
J Acquir Immune Defic Syndr 48:408-17. 2008..Antiretrovirals (ARVs) are recommended for maternal health and to reduce HIV-1 mother-to-child transmission, but suboptimal adherence can counteract its benefits...
CD4+/CD8+ T cell ratio for diagnosis of HIV-1 infection in infants: Women and Infants Transmission StudySavita Pahwa
Department of Microbiology and Immunology, University of Miami, Miller School of Medicine, Miami, Florida 33136, USA
Pediatrics 122:331-9. 2008..In this study, we tested the hypothesis that the CD4(+)/CD8(+) T cell ratio could predict HIV infection status in HIV-exposed infants...
Morbidity and mortality among a cohort of human immunodeficiency virus type 1-infected and uninfected pregnant women and their infants from Malawi, Zambia, and TanzaniaDavid Chilongozi
University of North Carolina Project, Lilongwe, Malawi
Pediatr Infect Dis J 27:808-14. 2008..Morbidity and mortality patterns among pregnant women and their infants (before antiretroviral therapy was widely available) determines HIV-1 diagnostic, monitoring, and care interventions...
Impaired immunity to recall antigens and neoantigens in severely immunocompromised children and adolescents during the first year of effective highly active antiretroviral therapyMona Rigaud
New York University School of Medicine, New York, NY, USA
J Infect Dis 198:1123-30. 2008....
Mother-to-child transmission of HIV-1: strong association with certain maternal HLA-B alleles independent of viral load implicates innate immune mechanismsRobert Winchester
Columbia University, Department of Pediatrics, New York, NY 10032, USA
J Acquir Immune Defic Syndr 36:659-70. 2004....
Infectious disease morbidity among young HIV-1-exposed but uninfected infants in Latin American and Caribbean countries: the National Institute of Child Health and Human Development International Site Development Initiative Perinatal StudyMarisa M Mussi-Pinhata
University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil
Pediatrics 119:e694-704. 2007..The goal was to describe the frequency, characteristics, and correlates of infectious disease morbidity during the first 6 months of life among HIV-1-exposed but uninfected infants...
Fetal fibronectin and adverse infant outcomes in a predominantly human immunodeficiency virus-infected African population: a randomized controlled trialRobert L Goldenberg
Department of Obstetrics and Gynecology, University of Alabama at Birmingham, 1500 6th Avenue South, Birmingham, AL 35233, USA
Obstet Gynecol 109:392-401. 2007..To evaluate the relationship between fetal fibronectin and preterm birth and maternal-to-child transmission of human immunodeficiency virus (HIV) in an African population of predominantly HIV-infected women...
Participation of HIV-infected pregnant women in research in the United StatesSusan Brogly
Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, MA 02115 6017, USA
AIDS Res Hum Retroviruses 23:51-3. 2007..This high rate of nonenrollment can bias study results and generate findings that are applicable only to particular groups of women. Efforts should be taken to design protocols that facilitate enrollment of HIV-infected pregnant women...
Impact of pregnancy on abacavir pharmacokineticsBrookie M Best
University of California San Diego, California 92103 8214, USA
AIDS 20:553-60. 2006..To describe abacavir pharmacokinetics during pregnancy and postpartum; physiological changes during pregnancy are known to affect antiretroviral drug disposition...
Mode of delivery and postpartum HIV-1 disease progression: the Women and Infants Transmission StudyElena L Navas-Nacher
Children's Memorial Medical Center, Chicago, Illinois, USA
AIDS 20:429-36. 2006..66 years. CONCLUSIONS: The present results suggest that, among HIV-1-infected women in North America, mode of delivery is not associated with subsequent HIV-1 disease progression...
Timing of maternal and neonatal dosing of nevirapine and the risk of mother-to-child transmission of HIV-1: HIVNET 024Benjamin H Chi
University of Alabama at Birmingham, Department of Obstetrics and Gynecology, Birmingham, Alabama, USA
AIDS 19:1857-64. 2005..We analyzed data from a multicenter clinical trial to determine whether timing of maternal or infant NVP was associated with MTCT between delivery and 6 weeks of age (intrapartum/early postnatal transmission; I/EP)...
The rate of serious bacterial infections among HIV-infected children with immune reconstitution who have discontinued opportunistic infection prophylaxisSharon Nachman
Department of Pediatrics, Stony Brook University, Stony Brook, NY 11794 8111, USA
Pediatrics 115:e488-94. 2005....
Morbidity and mortality during the first two years of life among uninfected children born to human immunodeficiency virus type 1-infected women: the women and infants transmission studyMary E Paul
Baylor College of Medicine, Houston, TX, USA
Pediatr Infect Dis J 24:46-56. 2005....
Late postnatal transmission of HIV-1 in breast-fed children: an individual patient data meta-analysisAnna Coutsoudis
J Infect Dis 189:2154-66. 2004..Biological and cultural mechanisms underlying the association between sex and late postnatal transmission should be further investigated. Interventions to decrease transmission of HIV-1 through breast-feeding are urgently needed...
Breast-feeding and Transmission of HIV-1Grace John-Stewart
Department of Medicine, University of Washington, USA
J Acquir Immune Defic Syndr 35:196-202. 2004..Innate and acquired immune factors may act most effectively in combination to prevent primary HIV-1 infection by breast milk...
Prevention of HIV transmission through breast-feeding: strengthening the research agendaFrancois Dabis
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, University College, London, UK
J Acquir Immune Defic Syndr 35:167-8. 2004..These papers summarize the current state of knowledge and highlight the outstanding issues that will need to be addressed in the very near future before research advances can be translated into public health practice...
Human milk, breastfeeding, and transmission of human immunodeficiency virus type 1 in the United States. American Academy of Pediatrics Committee on Pediatric AIDSJennifer S Read
Pediatrics 112:1196-205. 2003..This technical report summarizes the information available regarding breastfeeding transmission of HIV-1...
Cell-associated genital tract virus and vertical transmission of human immunodeficiency virus type 1 in antiretroviral-experienced womenRuth E Tuomala
Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
J Infect Dis 187:375-84. 2003..28; 95% CI, 1.09-4.78; P=.03). The cell-associated genital tract compartment is important in the pathophysiology and prevention of vertical HIV-1 transmission...
Mode of delivery and postpartum morbidity in Latin American and Caribbean countries among women who are infected with human immunodeficiency virus-1: the NICHD International Site Development Initiative (NISDI) Perinatal StudyGeraldo Duarte
School of Medicine, University of Sao Paulo, Ribeirao Preto, Brazil
Am J Obstet Gynecol 195:215-29. 2006..Mode of delivery was associated with postpartum morbidity, possibly reflecting the larger proportion of minor postpartum morbidity events among those with cesarean delivery after labor and/or after ruptured membranes...
Drug resistance among HIV-infected pregnant women receiving antiretrovirals for prophylaxisAdriana S Duran
Hosp General de Agudos Jose Maria Ramos Mejia, Buenos Aires, Argentina
AIDS 21:199-205. 2007..To quantify primary resistance mutations (PRMs) among HIV-1-infected women receiving antiretroviral therapy (ART) for prevention of mother-to-child transmission (MTCT)...
HIV-1 vaccine induced immune responses in newborns of HIV-1 infected mothersElizabeth J McFarland
Department of Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Denver Colorado, USA
AIDS 20:1481-9. 2006..This study evaluated the safety and immunogenicity of ALVAC HIV-1 vaccine with and without a subunit envelope boost in infants born to HIV-1-infected women...
Maternal antiretroviral drugs during pregnancy and infant low birth weight and preterm birthEdgardo G Szyld
Hosp Diego Paroissien, Brazil
AIDS 20:2345-53. 2006..The a priori hypothesis was that protease inhibitor (PI)-containing regimens are associated with an increased risk of LBW and preterm birth...
Predictors of repeat pregnancy among HIV-1-infected womenAllison S Bryant
University of California, San Francisco, San Francisco, CA 94143, USA
J Acquir Immune Defic Syndr 44:87-92. 2007..We examined predictors of repeat pregnancy among HIV-1-infected women enrolled in the Women and Infants Transmission Study (WITS)...
Correlates of syphilis seroreactivity among pregnant women: the HIVNET 024 Trial in Malawi, Tanzania, and ZambiaDara Potter
School of Public Health, University of Alabama at Birmingham, USA
Sex Transm Dis 33:604-9. 2006..Younger HIV-infected women were at highest risk. Universal integrated antenatal HIV and syphilis screening and treatment is essential in sub-Saharan African settings...
Tolerance and safety of different concentrations of chlorhexidine for peripartum vaginal and infant washes: HIVNET 025Craig M Wilson
Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA
J Acquir Immune Defic Syndr 35:138-43. 2004..We evaluated different concentrations (0.25%, 1%, and 2%) of chlorhexidine (CHX) for perinatal maternal and infant washes to identify the maximum tolerable concentration of CHX for such an intervention...
Analysis of HIV type 1 diversity in pregnant women from four Latin American and Caribbean countriesManuel Gomez-Carrillo
Centro Nacional de Referencia para el SIDA, School of Medicine, University of Buenos Aires, Buenos Aires, Argentina
AIDS Res Hum Retroviruses 22:1186-91. 2006..The different patterns of HIV- 1 subtypes and intersubtype recombinants in South America (Argentina and Brazil) compared to those in Central and North America should be considered in the design of future HIV-1 vaccine trials...
Persistent parvovirus B19 infection without the development of chronic anemia in HIV-infected and -uninfected children: the Women and Infants Transmission StudyAshley C LaMonte
Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 189:847-51. 2004..Of the 5 children, none had evidence of B19-associated anemia. Our data suggest that B19 infections can persist in children without the development of symptomatic anemia...
CD4/CD8 T-cell ratio predicts HIV infection in infants: the National Heart, Lung, and Blood Institute P2C2 StudyWilliam T Shearer
Department of Pediatrics, Section of Allergy and Immunology, Baylor College of Medicine, Houston, TX, USA
J Allergy Clin Immunol 120:1449-56. 2007..In resource-poor regions of the world, HIV virologic testing is not available...
Reduced lopinavir exposure during pregnancyAlice M Stek
Department of Obstetrics and Gynecology, University of Southern California School of Medicine, Los Angeles, CA, USA
AIDS 20:1931-9. 2006..Pregnancy can alter antiretroviral pharmacokinetics. Our objective was to describe lopinavir/ritonavir (LPV/r) pharmacokinetics during pregnancy...
HPTN 024 study: histologic chorioamnionitis, antibiotics and adverse infant outcomes in a predominantly HIV-1-infected African populationRobert L Goldenberg
Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL 35233 1602, USA
Am J Obstet Gynecol 195:1065-74. 2006..Histologic chorioamnionitis has been associated with preterm birth and low birthweight. Our goal was to evaluate the relationship between polymorphonuclear cell and mononuclear cell placental infiltrations and adverse infant outcomes...
Safety and immunogenicity of an HIV-1 recombinant canarypox vaccine in newborns and infants of HIV-1-infected womenDaniel C Johnson
Sinai Children s Hospital and Rosalind Franklin University of Medicine and Science, North Chicago, IL 60608, USA
J Infect Dis 192:2129-33. 2005..33) TCID(50) vaccine formulation). Rare mucosal immunoglobulin A responses and no measurable vaccine-elicited serum antibodies were detected. In children, vCP205 appeared to be safe and immunogenic...
Diagnosis of HIV-1 infection in children younger than 18 months in the United StatesJennifer S Read
Pediatrics 120:e1547-62. 2007..For breastfeeding infants, a similar testing algorithm can be followed, with timing of testing starting from the date of complete cessation of breastfeeding instead of the date of birth...
A phase III clinical trial of antibiotics to reduce chorioamnionitis-related perinatal HIV-1 transmissionTaha E Taha
Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, 615 N Wolfe Street, Baltimore, MD 21205, USA
AIDS 20:1313-21. 2006..A multisite study was conducted in Africa to assess the efficacy of antibiotics to reduce mother-to-child transmission (MTCT) of HIV-1...
The HPTN 024 Study: the efficacy of antibiotics to prevent chorioamnionitis and preterm birthRobert L Goldenberg
Department of Obstetrics and Gynecology, University of Alabama, Birmingham, AL, USA
Am J Obstet Gynecol 194:650-61. 2006..The use of antibiotics to prevent preterm birth has achieved mixed results. Our goal in this study was to determine if antibiotics given prenatally and during labor reduce the incidence of preterm birth and histologic chorioamnionitis...
