Yossef Raviv

Summary

Affiliation: National Cancer Institute
Country: USA

Publications

  1. ncbi request reprint Fluorescent lipid probes in the study of viral membrane fusion
    Robert Blumenthal
    Laboratory of Experimental and Computational Biology, Center for Cancer Research, SAIC, P O Box B, Bldg 469, Rm 216A, Miller Drive, NCI Frederick, MD 21702 1201, USA
    Chem Phys Lipids 116:39-55. 2002
  2. ncbi request reprint Ebola virus inactivation with preservation of antigenic and structural integrity by a photoinducible alkylating agent
    Kelly L Warfield
    US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA
    J Infect Dis 196:S276-83. 2007
  3. pmc Hydrophobic inactivation of influenza viruses confers preservation of viral structure with enhanced immunogenicity
    Yossef Raviv
    Nanobiology Program, Center of Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA
    J Virol 82:4612-9. 2008
  4. pmc Inactivation of retroviruses with preservation of structural integrity by targeting the hydrophobic domain of the viral envelope
    Yossef Raviv
    Center for Cancer Research Nanobiology Program, NCI Frederick, Frederick, MD 21702, USA
    J Virol 79:12394-400. 2005
  5. pmc HIV-1 envelope glycoprotein-mediated fusion and pathogenesis: implications for therapy and vaccine development
    Amy Jacobs
    Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA
    Vaccine 26:3026-35. 2008
  6. pmc Orthogonal inactivation of influenza and the creation of detergent resistant viral aggregates: towards a novel vaccine strategy
    Julie M Belanger
    Center for Cancer Research Nanobiology Program, National Cancer Institute Frederick, Frederick, USA
    Virol J 9:72. 2012
  7. pmc Effects of UVA irradiation, aryl azides, and reactive oxygen species on the orthogonal inactivation of the human immunodeficiency virus (HIV-1)
    Julie M Belanger
    Center for Cancer Research Nanobiology Program, National Cancer Institute Frederick, Frederick, MD 21702, USA
    Virology 417:221-8. 2011
  8. ncbi request reprint The HIV Env-mediated fusion reaction
    Stephen A Gallo
    Laboratory of Experimental and Computational Biology, Center for Cancer Research, NCI Frederick, National Institute of Health, Miller Drive, Frederick, MD 21702 1201, USA
    Biochim Biophys Acta 1614:36-50. 2003
  9. pmc Photo-activation of the hydrophobic probe iodonaphthylazide in cells alters membrane protein function leading to cell death
    Mathias Viard
    Nanobiology Program, Center of Cancer Research, National Cancer Institute, Frederick, Maryland, USA
    BMC Cell Biol 10:21. 2009
  10. pmc Ectopic ATP synthase facilitates transfer of HIV-1 from antigen-presenting cells to CD4(+) target cells
    Amichai Yavlovich
    Membrane Structure and Function Section, Nanobiology Program, Center for Cancer Research, Bethesda, MD, USA
    Blood 120:1246-53. 2012

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Fluorescent lipid probes in the study of viral membrane fusion
    Robert Blumenthal
    Laboratory of Experimental and Computational Biology, Center for Cancer Research, SAIC, P O Box B, Bldg 469, Rm 216A, Miller Drive, NCI Frederick, MD 21702 1201, USA
    Chem Phys Lipids 116:39-55. 2002
    ..Thus, fluorescent lipid probes provide a broad repertoire of fusion assays and powerful tools to produce precise, quantitative data in real time required for the elucidation of the complex process of viral fusion...
  2. ncbi request reprint Ebola virus inactivation with preservation of antigenic and structural integrity by a photoinducible alkylating agent
    Kelly L Warfield
    US Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA
    J Infect Dis 196:S276-83. 2007
    ..Thus, INA may have significant potential for the development of vaccines and immunotherapeutics for filoviruses and other enveloped viruses...
  3. pmc Hydrophobic inactivation of influenza viruses confers preservation of viral structure with enhanced immunogenicity
    Yossef Raviv
    Nanobiology Program, Center of Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA
    J Virol 82:4612-9. 2008
    ..When used as a vaccine given intranasally (i.n.), INA-inactivated influenza virus induced immune responses similar to live virus infection...
  4. pmc Inactivation of retroviruses with preservation of structural integrity by targeting the hydrophobic domain of the viral envelope
    Yossef Raviv
    Center for Cancer Research Nanobiology Program, NCI Frederick, Frederick, MD 21702, USA
    J Virol 79:12394-400. 2005
    ..Targeting the lipid domain of biological membranes with hydrophobic alkylating compounds could be used as a general approach for inactivation of enveloped viruses and other pathogenic microorganisms for vaccine application...
  5. pmc HIV-1 envelope glycoprotein-mediated fusion and pathogenesis: implications for therapy and vaccine development
    Amy Jacobs
    Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA
    Vaccine 26:3026-35. 2008
    ..Taken as a whole, our studies have many different important implications for antiviral therapies and vaccine development...
  6. pmc Orthogonal inactivation of influenza and the creation of detergent resistant viral aggregates: towards a novel vaccine strategy
    Julie M Belanger
    Center for Cancer Research Nanobiology Program, National Cancer Institute Frederick, Frederick, USA
    Virol J 9:72. 2012
    ..Prolonged UVA irradiation in the presence of INA results in ROS-species formation, which in turn results in detergent resistant viral protein fractions...
  7. pmc Effects of UVA irradiation, aryl azides, and reactive oxygen species on the orthogonal inactivation of the human immunodeficiency virus (HIV-1)
    Julie M Belanger
    Center for Cancer Research Nanobiology Program, National Cancer Institute Frederick, Frederick, MD 21702, USA
    Virology 417:221-8. 2011
    ....
  8. ncbi request reprint The HIV Env-mediated fusion reaction
    Stephen A Gallo
    Laboratory of Experimental and Computational Biology, Center for Cancer Research, NCI Frederick, National Institute of Health, Miller Drive, Frederick, MD 21702 1201, USA
    Biochim Biophys Acta 1614:36-50. 2003
    ..A review of these data that may require an updated version of the original model is presented here...
  9. pmc Photo-activation of the hydrophobic probe iodonaphthylazide in cells alters membrane protein function leading to cell death
    Mathias Viard
    Nanobiology Program, Center of Cancer Research, National Cancer Institute, Frederick, Maryland, USA
    BMC Cell Biol 10:21. 2009
    ..The effects of INA-UV treatment on signaling via various cell surface receptors, on the activity of the multi-drug resistance transporter MRP1 and on membrane protein lateral mobility were also investigated...
  10. pmc Ectopic ATP synthase facilitates transfer of HIV-1 from antigen-presenting cells to CD4(+) target cells
    Amichai Yavlovich
    Membrane Structure and Function Section, Nanobiology Program, Center for Cancer Research, Bethesda, MD, USA
    Blood 120:1246-53. 2012
    ..We conclude that ectopic ATP synthase could be an accessible molecular target for inhibiting HIV-1 proliferation in vivo...
  11. pmc Characterization of the effects of aryl-azido compounds and UVA irradiation on the viral proteins and infectivity of human immunodeficiency virus type 1
    Julie M Belanger
    Center for Cancer Research Nanobiology Program, NCI Frederick, Frederick, MD, USA
    Photochem Photobiol 86:1099-108. 2010
    ....
  12. pmc Photoinduced reactivity of the HIV-1 envelope glycoprotein with a membrane-embedded probe reveals insertion of portions of the HIV-1 Gp41 cytoplasmic tail into the viral membrane
    Mathias Viard
    Center of Cancer Research Nanobiology Program, National Cancer Institute, National Institutes of Health, Frederick, Maryland 21702, USA
    Biochemistry 47:1977-83. 2008
    ..These results shed light on the disposition of the HIV-1 gp41 CT with respect to the membrane. Moreover, our data have general implications for topology of membrane proteins and their in situ interactions with the lipid bilayer...
  13. ncbi request reprint Quantitative measurement of fusion of HIV-1 and SIV with cultured cells using photosensitized labeling
    Yossef Raviv
    Laboratory of Experimental and Computational Biology, National Cancer Institute, National Institutes of Health, Frederick, Maryland 21702, USA
    Virology 293:243-51. 2002
    ..This feature provides a basis for understanding the mode of action of HIV/SIV entry inhibitors that target transition states...
  14. ncbi request reprint Improved separation of integral membrane proteins by continuous elution electrophoresis with simultaneous detergent exchange: application to the purification of the fusion protein of the human immunodeficiency virus type 1
    Mathias Viard
    Laboratory of Experimental and Computational Biology, Center for Cancer Research, NCI Frederick, Bldg 469, Rm 213, Miller Drive, Frederick, MD 21702, USA
    Electrophoresis 23:1659-66. 2002
    ..The possible application of this approach for the isolation of integral membrane proteins with the propensity to undergo spontaneous folding and aggregation is being discussed...
  15. ncbi request reprint Complete inactivation of Venezuelan equine encephalitis virus by 1,5-iodonaphthylazide
    Anuj Sharma
    Centre for Combat Casualty and Life Sustainment Research, Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
    Biochem Biophys Res Commun 358:392-8. 2007
    ..This data suggest that such inactivation strategies can be used for developing vaccine candidates for VEEV and other enveloped viruses...
  16. pmc Identification of PhIL1, a novel cytoskeletal protein of the Toxoplasma gondii pellicle, through photosensitized labeling with 5-[125I]iodonaphthalene-1-azide
    Stacey D Gilk
    Department of Microbiology and Molecular Genetics, 316 Stafford Hall, University of Vermont, Burlington, VT 05405, USA
    Eukaryot Cell 5:1622-34. 2006
    ..Detergent extraction and immunolocalization data suggest that PhIL1 associates with the parasite cytoskeleton...