R L Rabin

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Human Mig chemokine: biochemical and functional characterization
    F Liao
    Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Exp Med 182:1301-14. 1995
  2. ncbi request reprint Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor
    D Weissman
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Nature 389:981-5. 1997
  3. pmc The nexus between atopic disease and autoimmunity: a review of the epidemiological and mechanistic literature
    R L Rabin
    Center for Biologics Evaluation and Research, USFDA, Bethesda, MD 20892 4555, USA
    Clin Exp Immunol 153:19-30. 2008
  4. pmc CCR5 signal transduction in macrophages by human immunodeficiency virus and simian immunodeficiency virus envelopes
    J Arthos
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Virol 74:6418-24. 2000
  5. pmc A role for the Tec family tyrosine kinase Txk in T cell activation and thymocyte selection
    C L Sommers
    Laboratory of Mammalian Genes and Development, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Exp Med 190:1427-38. 1999
  6. ncbi request reprint CXCR4 and CCR5 on human thymocytes: biological function and role in HIV-1 infection
    M B Zaitseva
    Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 161:3103-13. 1998
  7. ncbi request reprint Chemokine receptor responses on T cells are achieved through regulation of both receptor expression and signaling
    R L Rabin
    Laboratory of Clinical Investigation, Flow Cytometry Unit, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA
    J Immunol 162:3840-50. 1999
  8. ncbi request reprint Activation of the formyl peptide receptor by the HIV-derived peptide T-20 suppresses interleukin-12 p70 production by human monocytes
    M C Braun
    Immune Cell Interaction Unit, Mucosal Immunity Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Blood 97:3531-6. 2001
  9. pmc HIV-1 Tat protein mimicry of chemokines
    A Albini
    Centro di Biotecnologie Avanzate, Istituto Nazionale per la Ricerca sul Cancro, Largo Rosanna Benzi, 10, 16132 Genoa, Italy
    Proc Natl Acad Sci U S A 95:13153-8. 1998
  10. ncbi request reprint Direct inhibition of Bruton's tyrosine kinase by IBtk, a Btk-binding protein
    W Liu
    Department of Clinical and Experimental Medicine, Medical School, University of Catanzaro, 88100 Catanzaro, Italy
    Nat Immunol 2:939-46. 2001

Collaborators

Detail Information

Publications10

  1. pmc Human Mig chemokine: biochemical and functional characterization
    F Liao
    Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Exp Med 182:1301-14. 1995
    ..It is likely that HuMig plays a role in T cell trafficking and perhaps in other aspects of the physiology of activated T cells...
  2. ncbi request reprint Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor
    D Weissman
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Nature 389:981-5. 1997
    ..Alternatively, envelope-mediated CCR5 signal transduction may influence viral-associated cytopathicity or apoptosis...
  3. pmc The nexus between atopic disease and autoimmunity: a review of the epidemiological and mechanistic literature
    R L Rabin
    Center for Biologics Evaluation and Research, USFDA, Bethesda, MD 20892 4555, USA
    Clin Exp Immunol 153:19-30. 2008
    ..Because the ultimate goal is to ameliorate or cure these diseases, our discussion may help to predict or interpret unexpected consequences of novel therapeutic agents used to target autoimmune or atopic diseases...
  4. pmc CCR5 signal transduction in macrophages by human immunodeficiency virus and simian immunodeficiency virus envelopes
    J Arthos
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Virol 74:6418-24. 2000
    ..The data presented here are consistent with this hypothesis and suggest that the differential capacity of viral envelopes to signal through CCR5 may influence their ability to replicate in macrophages...
  5. pmc A role for the Tec family tyrosine kinase Txk in T cell activation and thymocyte selection
    C L Sommers
    Laboratory of Mammalian Genes and Development, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Exp Med 190:1427-38. 1999
    ..These results identify a role for Txk in TCR signal transduction, T cell development, and selection and suggest that the Tec family kinases Itk and Txk perform analogous functions...
  6. ncbi request reprint CXCR4 and CCR5 on human thymocytes: biological function and role in HIV-1 infection
    M B Zaitseva
    Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 161:3103-13. 1998
    ..Our data provide strong evidence that CXCR4 and CCR5 function as coreceptors for HIV-1 infection of human thymocytes...
  7. ncbi request reprint Chemokine receptor responses on T cells are achieved through regulation of both receptor expression and signaling
    R L Rabin
    Laboratory of Clinical Investigation, Flow Cytometry Unit, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA
    J Immunol 162:3840-50. 1999
    ....
  8. ncbi request reprint Activation of the formyl peptide receptor by the HIV-derived peptide T-20 suppresses interleukin-12 p70 production by human monocytes
    M C Braun
    Immune Cell Interaction Unit, Mucosal Immunity Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Blood 97:3531-6. 2001
    ..These findings provide a potential direct mechanism for HIV-mediated suppression of IL-12 production and suggest a broader role for G-protein-coupled receptors in the regulation of innate immune responses. (Blood. 2001;97:3531-3536)..
  9. pmc HIV-1 Tat protein mimicry of chemokines
    A Albini
    Centro di Biotecnologie Avanzate, Istituto Nazionale per la Ricerca sul Cancro, Largo Rosanna Benzi, 10, 16132 Genoa, Italy
    Proc Natl Acad Sci U S A 95:13153-8. 1998
    ..HIV-1 Tat appears to mimic beta-chemokine features, which may serve to locally recruit chemokine receptor-expressing monocytes/macrophages toward HIV producing cells and facilitate activation and infection...
  10. ncbi request reprint Direct inhibition of Bruton's tyrosine kinase by IBtk, a Btk-binding protein
    W Liu
    Department of Clinical and Experimental Medicine, Medical School, University of Catanzaro, 88100 Catanzaro, Italy
    Nat Immunol 2:939-46. 2001
    ..IBtk downregulated Btk kinase activity, Btk-mediated calcium mobilization and nuclear factor-kappaB-driven transcription. These results define a potential mechanism for the regulation of Btk function in B cells...