Research Topics
| Calman PrussinSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Interferon-gamma coordinates CCL3-mediated neutrophil recruitment in vivoCynthia A Bonville
SUNY Upstate Medical University, Syracuse, New York 13210, USA
BMC Immunol 10:14. 2009....
Effect of anti-IgE therapy on food allergen specific T cell responses in eosinophil associated gastrointestinal disordersBarbara Foster
Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
Clin Mol Allergy 9:7. 2011..abstract:..
T(H)2 heterogeneity: Does function follow form?Calman Prussin
Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 1881, USA
J Allergy Clin Immunol 126:1094-8. 2010....
Eosinophilic gastrointestinal disease and peanut allergy are alternatively associated with IL-5+ and IL-5(-) T(H)2 responsesCalman Prussin
Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 1881, USA
J Allergy Clin Immunol 124:1326-32.e6. 2009..Both anaphylactic food allergy and eosinophil-associated gastrointestinal disorders are associated with T(H)2 responses and food-specific IgE, yet they have very different clinical presentations...
IgE, mast cells, basophils, and eosinophilsKelly D Stone
Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 1881, USA
J Allergy Clin Immunol 125:S73-80. 2010..Mast cells, basophils, and eosinophils are central effector cells in allergic inflammation, as well as in innate and adaptive immunity. This review highlights what is known about these components and their roles in disease pathogenesis...
Anti-IgE treatment of eosinophil-associated gastrointestinal disordersShabnam Foroughi
Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
J Allergy Clin Immunol 120:594-601. 2007..Eosinophil-associated gastrointestinal disorders (EGIDs) are commonly associated with atopy and are being recognized with increasing frequency. Current therapy for EGIDs is inadequate...
5. IgE, mast cells, basophils, and eosinophilsCalman Prussin
Laboratory of Allergic Diseases, National Institutes of Allergy and Infectious Disease, National Institutes of Health, Building 10, Rm. 11C-205, 10 Center Drive, Bethesda, MD 20892, USA
J Allergy Clin Immunol 117:S450-6. 2006..Aggregation of receptor-bound IgE molecules on re-exposure to specific allergen results in the production of mediators that produce the allergic response. Principal among the cells drawn to sites of mediator release is the eosinophil...
Hierarchical IL-5 expression defines a subpopulation of highly differentiated human Th2 cellsBhaskar Upadhyaya
Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
J Immunol 187:3111-20. 2011..These results demonstrate that IL-5(+) and IL-5(-) Th2 cells, respectively, represent more and less highly differentiated Th2 cell subpopulations. Such Th2 subpopulations may differentially contribute to Th2-driven pathology...
Rebound eosinophilia after treatment of hypereosinophilic syndrome and eosinophilic gastroenteritis with monoclonal anti-IL-5 antibody SCH55700Yae-Jean Kim
NIAID, NIH, Bethesda, MD 20892, USA
J Allergy Clin Immunol 114:1449-55. 2004..CONCLUSIONS: The rebound eosinophilia after SCH55700 treatment is a result of a serum factor that enhances eosinophil survival. Reversal of this effect by the addition of antibody to IL-5 suggests that this factor may be IL-5 itself...
Detection of intracellular cytokines by flow cytometryBarbara Foster
National Institute of Allergy and Infectious Diseases NIH, Bethesda, Maryland, USA
Curr Protoc Immunol . 2007..A protocol in which brefeldin A is used to identify cytokine-producing T cells activated in response to in vivo contact with microbial antigens is also described...
Human dendritic cell 1 and dendritic cell 2 subsets express FcepsilonRI: correlation with serum IgE and allergic asthmaBarbara Foster
Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-1881, USA
J Allergy Clin Immunol 112:1132-8. 2003..These data support the concept that novel therapeutic approaches directly targeted at FcepsilonRI expression would affect both the sensitization and the effector phases of the allergen-specific immune response...
Omalizumab treatment downregulates dendritic cell FcepsilonRI expressionCalman Prussin
Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
J Allergy Clin Immunol 112:1147-54. 2003..CONCLUSION: These results demonstrate that anti-IgE therapy causes a rapid decrease in DC surface FcepsilonRI expression and establish that IgE is an important regulator of FcepsilonRI expression by DCs...
4. IgE, mast cells, basophils, and eosinophilsCalman Prussin
Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases/NIH, Building 10, Room 11C205, 10 Center Drive, Bethesda, MD 20892-1881, USA
J Allergy Clin Immunol 111:S486-94. 2003..Principal among the cells drawn to sites of mediator release is the eosinophil...
Inflammatory responses to pneumovirus infection in IFN-alpha beta R gene-deleted miceTara L Garvey
Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
J Immunol 175:4735-44. 2005....
Clinical management of eosinophilic gastrointestinal disordersShabnam Foroughi
Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-1881, USA
Curr Allergy Asthma Rep 5:259-61. 2005
Abnormal differentiation of memory T cells in systemic lupus erythematosusRuth D Fritsch
NIAMS, NIH, Building 10, Room 6D47C, 9000 Rockville Pike, Bethesda, MD 20892, USA
Arthritis Rheum 54:2184-97. 2006..The goal of this study was to examine maturational disturbances in CD4 T cell differentiation in systemic lupus erythematosus (SLE), using these phenotypic markers...
CD40 agonist antibody mediated improvement of chronic Cryptosporidium infection in patients with X-linked hyper IgM syndromeXiying Fan
Laboratory of Host Defenses, National Institutes of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA
Clin Immunol 143:152-61. 2012..This study demonstrates that CP-870,893 suppressed oocysts shedding in XHM patients with biliary cryptosporidiosis. The continued study of CD40 agonists in XHM is warranted...
IgE(+), Kit(-), I-A/I-E(-) myeloid cells are the initial source of Il-4 after antigen challenge in a mouse model of allergic pulmonary inflammationStefano Luccioli
Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20852, USA
J Allergy Clin Immunol 110:117-24. 2002..These data thus suggest that strategies targeting basophils should be considered in the treatment of early lung inflammation...
