R M Post

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Mood switch in bipolar depression: comparison of adjunctive venlafaxine, bupropion and sertraline
    R M Post
    Department of Health and Human Services, National Institute of Mental Health, Bethesda, Maryland, USA
    Br J Psychiatry 189:124-31. 2006
  2. ncbi The Stanley Foundation Bipolar Treatment Outcome Network. I. Longitudinal methodology
    G S Leverich
    Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892 1272, USA
    J Affect Disord 67:33-44. 2001
  3. ncbi The Stanley Foundation Bipolar Treatment Outcome Network. II. Demographics and illness characteristics of the first 261 patients
    T Suppes
    The Stanley Foundation Bipolar Network, 5430 Grosvenor Lane, Suite 200, Bethesda, MD 20814, USA
    J Affect Disord 67:45-59. 2001
  4. ncbi Clozapine in bipolar disorder: treatment implications for other atypical antipsychotics
    M A Frye
    National Institute of Mental Health, Biological Psychiatry Branch, Bethesda, MD, USA
    J Affect Disord 48:91-104. 1998
  5. ncbi The Stanley Foundation Bipolar Network. I. Rationale and methods
    R M Post
    National Institute of Mental Health, Bethesda, Maryland, USA
    Br J Psychiatry Suppl 41:s169-76. 2001
  6. ncbi Understanding emotional prosody activates right hemisphere regions
    M S George
    Biological Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
    Arch Neurol 53:665-70. 1996
  7. ncbi Rate of switch in bipolar patients prospectively treated with second-generation antidepressants as augmentation to mood stabilizers
    R M Post
    Biological Psychiatry Branch, NIMH, NIH, Bethesda, MD 20892-1272, USA
    Bipolar Disord 3:259-65. 2001
  8. ncbi Gabapentin does not alter single-dose lithium pharmacokinetics
    M A Frye
    Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    J Clin Psychopharmacol 18:461-4. 1998
  9. ncbi Amygdala-kindled seizures increase the expression of corticotropin-releasing factor (CRF) and CRF-binding protein in GABAergic interneurons of the dentate hilus
    M A Smith
    Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
    Brain Res 745:248-56. 1997
  10. ncbi Lack of adverse cognitive effects of 1 Hz and 20 Hz repetitive transcranial magnetic stimulation at 100% of motor threshold over left prefrontal cortex in depression
    A M Speer
    Biological Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    J ECT 17:259-63. 2001

Detail Information

Publications35

  1. ncbi Mood switch in bipolar depression: comparison of adjunctive venlafaxine, bupropion and sertraline
    R M Post
    Department of Health and Human Services, National Institute of Mental Health, Bethesda, Maryland, USA
    Br J Psychiatry 189:124-31. 2006
    ..Few studies have examined the relative risks of switching into hypomania or mania associated with second-generation antidepressant drugs in bipolar depression...
  2. ncbi The Stanley Foundation Bipolar Treatment Outcome Network. I. Longitudinal methodology
    G S Leverich
    Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892 1272, USA
    J Affect Disord 67:33-44. 2001
    ..This article describes the rationale for the Network, its guiding principles, methods, and study design to systematically assess the highly variable course of bipolar illness and its response to current and future treatments...
  3. ncbi The Stanley Foundation Bipolar Treatment Outcome Network. II. Demographics and illness characteristics of the first 261 patients
    T Suppes
    The Stanley Foundation Bipolar Network, 5430 Grosvenor Lane, Suite 200, Bethesda, MD 20814, USA
    J Affect Disord 67:45-59. 2001
    ..This report describes the demographics and course of illness characteristics of this study population...
  4. ncbi Clozapine in bipolar disorder: treatment implications for other atypical antipsychotics
    M A Frye
    National Institute of Mental Health, Biological Psychiatry Branch, Bethesda, MD, USA
    J Affect Disord 48:91-104. 1998
    ..The foregoing agents and future drugs with atypical neuroleptic properties should come to play an increasingly important role, compared to the older classical neuroleptics, in the acute and long term management of bipolar disorder...
  5. ncbi The Stanley Foundation Bipolar Network. I. Rationale and methods
    R M Post
    National Institute of Mental Health, Bethesda, Maryland, USA
    Br J Psychiatry Suppl 41:s169-76. 2001
    ..CONCLUSIONS: Well-characterised patients are followed in a detailed continuous longitudinal fashion in both opportunistic case series and double-blind, randomised controlled trials with reliable and validated measures...
  6. ncbi Understanding emotional prosody activates right hemisphere regions
    M S George
    Biological Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
    Arch Neurol 53:665-70. 1996
    ..The brain regions involved in recognition of emotional prosody in healthy subjects is less clear...
  7. ncbi Rate of switch in bipolar patients prospectively treated with second-generation antidepressants as augmentation to mood stabilizers
    R M Post
    Biological Psychiatry Branch, NIMH, NIH, Bethesda, MD 20892-1272, USA
    Bipolar Disord 3:259-65. 2001
    ..Individual data on each drug will be assessed in the next phase of the study after more subjects are recruited and the blind is broken...
  8. ncbi Gabapentin does not alter single-dose lithium pharmacokinetics
    M A Frye
    Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    J Clin Psychopharmacol 18:461-4. 1998
    ....
  9. ncbi Amygdala-kindled seizures increase the expression of corticotropin-releasing factor (CRF) and CRF-binding protein in GABAergic interneurons of the dentate hilus
    M A Smith
    Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
    Brain Res 745:248-56. 1997
    ..These results suggest that CRF may contribute to the development of amygdala kindling. However, the compensatory induction of CRF-BP may serve to limit the excitatory effects of CRF in the dentate gyrus...
  10. ncbi Lack of adverse cognitive effects of 1 Hz and 20 Hz repetitive transcranial magnetic stimulation at 100% of motor threshold over left prefrontal cortex in depression
    A M Speer
    Biological Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    J ECT 17:259-63. 2001
    ..This study assesses the cognitive performance of depressed patients receiving high or low frequency rTMS for 10 days...
  11. ncbi Opposite effects of high and low frequency rTMS on mood in depressed patients: relationship to baseline cerebral activity on PET
    A M Speer
    Biological Psychiatry Branch, NIMH, NIH, Bethesda, Maryland, United States
    J Affect Disord 115:386-94. 2009
    ..Optimal parameters of rTMS for antidepressant efficacy in general, or within patients, have not been adequately delineated...
  12. ncbi Mood improvement following daily left prefrontal repetitive transcranial magnetic stimulation in patients with depression: a placebo-controlled crossover trial
    M S George
    Biological Psychiatry Branch, NIMH, Bethesda, MD 20892, USA
    Am J Psychiatry 154:1752-6. 1997
    ..Preliminary studies have indicated that daily left prefrontal repetitive transcranial magnetic stimulation might have antidepressant activity. The authors sought to confirm this finding by using a double-blind crossover design...
  13. ncbi Blunted left cingulate activation in mood disorder subjects during a response interference task (the Stroop)
    M S George
    Biological Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    J Neuropsychiatry Clin Neurosci 9:55-63. 1997
    ..This study supports theories of blunted limbic and paralimbic activation and abnormal cingulate activity in depression and adds to the growing knowledge of the functional neuroanatomy of depression...
  14. ncbi Relationship between prior course of illness and neuropsychological functioning in patients with bipolar disorder
    K D Denicoff
    Section on Psychobiology, Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
    J Affect Disord 56:67-73. 1999
    ..This study investigated the relationship between prior course of illness and neuropsychological deficits in relatively high functioning outpatients with bipolar disorder...
  15. ncbi Relationship between prior course of illness and neuroanatomic structures in bipolar disorder: a preliminary study
    S O Ali
    Section on Psychobiology, Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    Neuropsychiatry Neuropsychol Behav Neurol 14:227-32. 2001
    ..CONCLUSIONS: Additional studies are needed to both replicate and further examine the association of prior course of illness and larger hippocampal and ventricular volumes in bipolar disorder...
  16. ncbi Autoradiographic analysis of serotonin receptors and transporter in kindled rat brain
    M Clark
    Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892
    Neurosci Lett 161:21-6. 1993
    ..Alterations in 5-HT receptors and the 5-HT transporter may endogenously modulate kindled seizures. Additionally, autoradiography of adenosine A1 receptors revealed no change for these receptors in any brain region...
  17. ncbi Effect of prefrontal repetitive transcranial magnetic stimulation in obsessive-compulsive disorder: a preliminary study
    B D Greenberg
    Laboratory of Clinical Science, NIMH, Bethesda, MD 20892 1264, USA
    Am J Psychiatry 154:867-9. 1997
    ..Prefrontal mechanisms are implicated in obsessive-compulsive disorder. The authors investigated whether prefrontal repetitive transcranial magnetic stimulation influenced obsessive-compulsive disorder symptoms...
  18. ncbi Effect of cocaine, lidocaine kindling and carbamazepine on batrachotoxin-induced phosphoinositide hydrolysis in rat brain slices
    R L Margolis
    Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892
    Brain Res 614:185-90. 1993
    ..Neither in vitro nor in vivo carbamazepine altered the effect of cocaine on BTX-induced PI hydrolysis. These results demonstrate that local anesthetic kindling does not alter PI hydrolysis coupled to Na channel or IBO activation...
  19. ncbi Elevated concentration of N-CAM VASE isoforms in schizophrenia
    M P Vawter
    Cellular Neurobiology Branch, NIDA IRP, Baltimore, MD 21224, USA
    J Psychiatr Res 34:25-34. 2000
    ..These results provide further evidence of an abnormality of N-CAM protein in chronic schizophrenia and suggest differences between schizophrenia and affective disorders in regulation of N-CAM...
  20. ncbi Rat nurr1 is prominently expressed in perirhinal cortex, and differentially induced in the hippocampal dentate gyrus by electroconvulsive vs. kindled seizures
    G Xing
    Biological Psychiatry Branch, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA
    Brain Res Mol Brain Res 47:251-61. 1997
    ..kindled seizures. In addition, as r-nurr1 is prominently expressed in the specific brain sites associated with memory acquisition and consolidation, it may play a role in memory processing...
  21. ncbi Neurobiology of seizures and behavioral abnormalities
    R M Post
    Biological Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1272, USA
    Epilepsia 45:5-14. 2004
    ....
  22. ncbi Developmental vulnerabilities to the onset and course of bipolar disorder
    R M Post
    Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892-1272, USA
    Dev Psychopathol 13:581-98. 2001
    ....
  23. ncbi Effects of thyroid alterations and carbamazepine on cortical beta-adrenergic receptors in the rat
    R T Joffe
    Biological Psychiatry Branch, NIMH, Bethesda, Maryland
    Neuropharmacology 27:171-4. 1988
    ....
  24. ncbi Apoptosis of hippocampal neurons after amygdala kindled seizures
    L X Zhang
    Biological Psychiatric Branch, NIMH, Bldg 10 Rm 3N212, Bethesda, MD 20982, USA
    Brain Res Mol Brain Res 55:198-208. 1998
    ....
  25. ncbi Benzodiazepine withdrawal delirium with catatonic features. Occurrence in patients with partial seizure disorders
    P Hauser
    Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892
    Arch Neurol 46:696-9. 1989
    ..High-dose benzodiazepine therapy and a history of viral encephalitis may be risk factors for withdrawal delirium...
  26. ncbi Comparative pharmacology of bipolar disorder and schizophrenia
    R M Post
    Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892 1272, USA
    Schizophr Res 39:153-8; discussion 163. 1999
    ....
  27. ncbi Specific amygdaloid nuclei are involved in suppression or propagation of epileptiform activity during transition stage between oral automatisms and generalized clonic seizures
    M Sitcoske O'Shea
    Biological Psychiatry Branch, National Institutes of Mental Health, Bethesda, MD 0892, USA
    Brain Res 873:1-17. 2000
    ..A neuroanatomical model of Am-induced seizure propagation is proposed suggesting that the Claust-Ins-PRh play a pivotal role during the transition between oral automatisms and generalized clonic convulsions...
  28. ncbi Lamotrigine reduces spontaneous and evoked GABAA receptor-mediated synaptic transmission in the basolateral amygdala: implications for its effects in seizure and affective disorders
    M F M Braga
    Department of Psychiatry, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, Maryland, MD 20814, USA
    Neuropharmacology 42:522-9. 2002
    ..The modulation of inhibitory synaptic transmission may be an important mechanism underlying the psychotropic effects of LTG...
  29. ncbi Kindling: separate vs. shared mechanisms in affective disorders and epilepsy
    S R Weiss
    Biological Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
    Neuropsychobiology 38:167-80. 1998
    ..It is hoped that some of the lessons from the kindling model will provide useful and novel insights into aspects of treatment and mechanisms of psychiatric and neurologic illnesses...
  30. ncbi Regional cerebral blood flow correlated with flashback intensity in patients with posttraumatic stress disorder
    E A Osuch
    Uniformed Services University of the Health Sciences, Maryland, USA
    Biol Psychiatry 50:246-53. 2001
    ..CONCLUSIONS: This study correlated flashback intensity and rCBF in a group of patients with chronic PTSD suggesting involvement of brainstem, and areas associated with motor control, complex visual/spatial cues and memory...
  31. ncbi Post-dexamethasone cortisol correlates with severity of depression before and during carbamazepine treatment in women but not men
    E A Osuch
    Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
    Acta Psychiatr Scand 104:397-401. 2001
    ..CONCLUSION: The pathophysiological implications of this selective positive relationship between severity of depression and post-DST cortisol in women, but not men, should be explored further...
  32. ncbi Input-specific LTP and depotentiation in the basolateral amygdala
    V Aroniadou-Anderjaska
    Department of Psychiatry, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA
    Neuroreport 12:635-40. 2001
    ..These synapse-specific, reversible changes in synaptic strength in the basolateral nucleus of the amygdala may be important to amygdala's role in emotional memory...
  33. ncbi Tranylcypromine vs. lamotrigine in the treatment of refractory bipolar depression: a failed but clinically useful study
    W A Nolen
    University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    Acta Psychiatr Scand 115:360-5. 2007
    ..To compare the efficacy and tolerability of tranylcypromine vs. lamotrigine in bipolar depression not responding to conventional antidepressants...
  34. ncbi Use of quetiapine in bipolar disorder: a case series with prospective evaluation
    T Suppes
    Int Clin Psychopharmacol 19:173-4. 2004
    ..Somatic complaints were limited. Mean (SD) duration before changes in medication regimens was 134 (100) days. Studies of the use of quetiapine in maintenance treatment of bipolar disorder are warranted...
  35. ncbi The role of psychosocial stress in the onset and progression of bipolar disorder and its comorbidities: the need for earlier and alternative modes of therapeutic intervention
    R M Post
    Penn State University School of Medicine, USA
    Dev Psychopathol 18:1181-211. 2006
    ..Without the mobilization of new clinical and public health approaches to earlier and more effective treatment and supportive interventions, bipolar illness will continue to have grave implications for many patients' long-term well being...