Audrey Player

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Gene expression analysis of RNA purified from embryonic stem cells and embryoid body-derived cells using a high-throughput microarray platform
    Audrey Player
    National Cancer Institute, Bethesda, Maryland, USA
    Curr Protoc Stem Cell Biol . 2007
  2. ncbi request reprint Comparisons between transcriptional regulation and RNA expression in human embryonic stem cell lines
    Audrey Player
    Advanced Technology Center, Microarray Facility, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Stem Cells Dev 15:315-23. 2006
  3. ncbi request reprint Global expression analysis of prostate cancer-associated stroma and epithelia
    Annely M Richardson
    Pathogenetics Unit, National Cancer Institute at Frederick, Frederick, MD, USA
    Diagn Mol Pathol 16:189-97. 2007
  4. ncbi request reprint Laser capture microdissection, microarrays and the precise definition of a cancer cell
    Audrey Player
    National Cancer Institute, Advanced Technology Center, Microarray Facility, Gaithersburg, MD 20877, USA
    Expert Rev Mol Diagn 4:831-40. 2004
  5. pmc Inactivation of LLC1 gene in nonsmall cell lung cancer
    Kyeong Man Hong
    Laboratory of Population Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Int J Cancer 120:2353-8. 2007
  6. ncbi request reprint Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer
    Junya Fukuoka
    Laboratory of Population Genetics, Biometric Research Branch, Center for Bioinformatics, Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland, USA
    Clin Cancer Res 10:4314-24. 2004
  7. pmc Three-dimensional mRNA measurements reveal minimal regional heterogeneity in esophageal squamous cell carcinoma
    Wusheng Yan
    Pathogenetics Unit, National Institutes of Health, Bethesda, Maryland 20892, USA
    Am J Pathol 182:529-39. 2013
  8. doi request reprint T7-based linear amplification of low concentration mRNA samples using beads and microfluidics for global gene expression measurements
    Jason G Kralj
    National Institute of Standards and Technology, 100 Bureau Dr MS 8313, Gaithersburg, MD, USA
    Lab Chip 9:917-24. 2009
  9. ncbi request reprint Identification of TDE2 gene and its expression in non-small cell lung cancer
    Audrey Player
    Laboratory of Population Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
    Int J Cancer 107:238-43. 2003
  10. ncbi request reprint Cyclin-dependent kinase 5 differentially regulates the transcriptional activity of the glucocorticoid receptor through phosphorylation: clinical implications for the nervous system response to glucocorticoids and stress
    Tomoshige Kino
    Reproductive Biology and Medicine Branch, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892, USA
    Mol Endocrinol 21:1552-68. 2007

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Gene expression analysis of RNA purified from embryonic stem cells and embryoid body-derived cells using a high-throughput microarray platform
    Audrey Player
    National Cancer Institute, Bethesda, Maryland, USA
    Curr Protoc Stem Cell Biol . 2007
    ..This unit suggests quality control metrics, summarizes the critical parameters necessary for obtaining reproducible experimental results, and outlines quantitative PCR methods for validating microarray results...
  2. ncbi request reprint Comparisons between transcriptional regulation and RNA expression in human embryonic stem cell lines
    Audrey Player
    Advanced Technology Center, Microarray Facility, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Stem Cells Dev 15:315-23. 2006
    ..Collectively, these data provide insight into the relationship between gene expression and transcriptional regulation, resulting in a reliable list of genes associated with hESCs...
  3. ncbi request reprint Global expression analysis of prostate cancer-associated stroma and epithelia
    Annely M Richardson
    Pathogenetics Unit, National Cancer Institute at Frederick, Frederick, MD, USA
    Diagn Mol Pathol 16:189-97. 2007
    ..These data provide insight into the molecular changes occurring in tumor-associated stromal cells and suggest new potential targets for future diagnostic, imaging, or therapeutic intervention...
  4. ncbi request reprint Laser capture microdissection, microarrays and the precise definition of a cancer cell
    Audrey Player
    National Cancer Institute, Advanced Technology Center, Microarray Facility, Gaithersburg, MD 20877, USA
    Expert Rev Mol Diagn 4:831-40. 2004
    ..Application of these experimental approaches to cancer studies may permit a more accurate definition of the biology of the cancer cell, so that ultimately, more specific targeted therapies can be developed...
  5. pmc Inactivation of LLC1 gene in nonsmall cell lung cancer
    Kyeong Man Hong
    Laboratory of Population Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Int J Cancer 120:2353-8. 2007
    ..These results suggest that inactivation of LLC1 by means of promoter methylation is a frequent event in nonsmall cell lung cancer and may play a role in lung tumorigenesis...
  6. ncbi request reprint Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer
    Junya Fukuoka
    Laboratory of Population Genetics, Biometric Research Branch, Center for Bioinformatics, Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland, USA
    Clin Cancer Res 10:4314-24. 2004
    ....
  7. pmc Three-dimensional mRNA measurements reveal minimal regional heterogeneity in esophageal squamous cell carcinoma
    Wusheng Yan
    Pathogenetics Unit, National Institutes of Health, Bethesda, Maryland 20892, USA
    Am J Pathol 182:529-39. 2013
    ..The present data indicate that, when analyzed using a standard array-based method at this level of histological resolution, ESCC contains little regional mRNA heterogeneity...
  8. doi request reprint T7-based linear amplification of low concentration mRNA samples using beads and microfluidics for global gene expression measurements
    Jason G Kralj
    National Institute of Standards and Technology, 100 Bureau Dr MS 8313, Gaithersburg, MD, USA
    Lab Chip 9:917-24. 2009
    ..Microfluidic IVT introduces no bias to the gene expression profile of the sample and provides more efficient transcription of mRNA sequences present at the single-cell level...
  9. ncbi request reprint Identification of TDE2 gene and its expression in non-small cell lung cancer
    Audrey Player
    Laboratory of Population Genetics, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
    Int J Cancer 107:238-43. 2003
    ..Alternatively, only 2 of 18 tumors and 8 of 14 adjacent nonmalignant bronchiole epithelium regions demonstrated negative to low levels of TDE2 signals...
  10. ncbi request reprint Cyclin-dependent kinase 5 differentially regulates the transcriptional activity of the glucocorticoid receptor through phosphorylation: clinical implications for the nervous system response to glucocorticoids and stress
    Tomoshige Kino
    Reproductive Biology and Medicine Branch, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892, USA
    Mol Endocrinol 21:1552-68. 2007
    ..Thus, CDK5 exerts some of its biological activities in neuronal cells through the GR, dynamically modulating GR transcriptional activity in a target promoter-dependent fashion...
  11. ncbi request reprint Characterization of mismatch and high-signal intensity probes associated with Affymetrix genechips
    Yonghong Wang
    SAIC Frederick, Inc, NCI Frederick, Frederick, Maryland 21702, USA
    Bioinformatics 23:2088-95. 2007
    ..A principal focus of this study was to investigate the nature of the MM signal intensities and demonstrate its contribution to the experimental results...
  12. pmc Identification of unique expression signatures and therapeutic targets in esophageal squamous cell carcinoma
    Wusheng Yan
    Pathogenetics Unit, Laboratory of Pathology, National Cancer Institute, Bethesda, USA
    BMC Res Notes 5:73. 2012
    ..abstract:..
  13. ncbi request reprint Nonclassic functions of human topoisomerase I: genome-wide and pharmacologic analyses
    Ze Hong Miao
    Laboratories of Molecular Pharmacology, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, Maryland, USA
    Cancer Res 67:8752-61. 2007
    ..The reported cell lines and approaches described in this article provide new tools to perform detailed functional analyses related to Top1 function...
  14. ncbi request reprint Nanotechnology, nanomedicine, and the development of new, effective therapies for cancer
    Ernest S Kawasaki
    National Cancer Institute, Gaithersburg, Maryland, USA
    Nanomedicine 1:101-9. 2005
    ..Finally, a new initiative--the National Cancer Institute Alliance for Nanotechnology in Cancer--will be described and discussed with respect to the scientific issues, policies, and funding...
  15. pmc Dynamic bookmarking of primary response genes by p300 and RNA polymerase II complexes
    Jung S Byun
    Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 106:19286-91. 2009
    ....
  16. pmc Identification of EpCAM as a molecular target of prostate cancer stroma
    Sumana Mukherjee
    Pathogenetics Unit, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 4605, USA
    Am J Pathol 175:2277-87. 2009
    ..Since the stromal compartment may be particularly accessible to vascular-delivered agents, epithelial cell adhesion activating molecule could become a valuable molecular target for imaging or treatment of prostate cancer...
  17. ncbi request reprint A preliminary transcriptome map of non-small cell lung cancer
    Takeshi Fujii
    Laboratory of Population Genetics, Center for Cancer Research, NIH, Bethesda, Maryland 20892, USA
    Cancer Res 62:3340-6. 2002
    ..Integrating chromosomal mapping information with gene expression profiles may help reveal novel molecular changes associated with human lung cancer...
  18. ncbi request reprint Frequent HIN-1 promoter methylation and lack of expression in multiple human tumor types
    Ian Krop
    Department of Medical Oncology, Dana Farber Cancer Institute, 44 Binney Street, D740C, Boston, MA 02115, USA
    Mol Cancer Res 2:489-94. 2004
    ..Thus, silencing of HIN-1 expression and methylation of its promoter occurs in multiple human cancer types, suggesting that elimination of HIN-1 function may contribute to several forms of epithelial tumorigenesis...