Research Topics
| P A PintoSummaryAffiliation: National Institutes of Health Country: USA Publications
| Collaborators
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Detail Information
Publications
A possible new syndrome with growth-hormone secreting pituitary adenoma, colonic polyposis, lipomatosis, lentigines and renal carcinoma in association with familial testicular germ cell malignancy: A case reportPhuong L Mai
Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
J Med Case Reports 1:9. 2007..Familial testicular cancer in the presence of other findings in affected and unaffected family members might indicate a previously-unidentified hereditary cancer syndrome...- Non-invasive monitoring of tissue oxygenation during laparoscopic donor nephrectomyNicole J Crane
Naval Medical Research Center, Combat Casualty Care, Silver Spring, MD 20910, USA
BMC Surg 8:8. 2008..However, there is no in vivo methodology to monitor renal parenchymal oxygenation during laparoscopic surgery... - Magnetic resonance imaging/ultrasound fusion guided prostate biopsy improves cancer detection following transrectal ultrasound biopsy and correlates with multiparametric magnetic resonance imagingPeter A Pinto
Urologic Oncology Branch, Clinical Center and National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 1210, USA
J Urol 186:1281-5. 2011..The cancer detection rates for the first 101 patients are reported... 
Renal carcinoma: minimally invasive surgery of the small renal massPeter A Pinto
Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Urol Oncol 27:335-6. 2009..Currently, minimally invasive partial nephrectomy has become an option in the treatment of small renal masses...
Tips and tricks of laparoscopic partial nephrectomyB McHone
Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Minerva Urol Nefrol 62:273-81. 2010..The following review is designed to assist the urologic surgeon in performing a successful laparoscopic partial nephrectomy by detailing the "tips and tricks" of the procedure...- BHD mutations, clinical and molecular genetic investigations of Birt-Hogg-Dubé syndrome: a new series of 50 families and a review of published reportsJ R Toro
Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Executive Plaza South, Room 7012, Rockville, MD 20892 7231, USA
J Med Genet 45:321-31. 2008..Germline mutations in BHD are associated with the susceptibility for BHDS. We previously described 51 BHDS families with BHD germline mutations... - Molecular diagnosis and therapy of kidney cancerW Marston Linehan
Urologic Oncology Branch, National Cancer Institute, Bethesda, Maryland 20892, USA
Annu Rev Med 61:329-43. 2010..Knowledge of these kidney cancer gene pathways has enabled new approaches in the management of this disease and has provided the foundation for the development of targeted therapeutics... - Hereditary kidney cancer: unique opportunity for disease-based therapyW Marston Linehan
Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Building 10 CRC, Room 1 5940, Bethesda, MD 20892 1107, USA
Cancer 115:2252-61. 2009..Studies of the tricarboxylic acid cycle and the VHL-HIF pathways have provided the foundation for therapeutic approaches in patients with HLRCC-associated kidney cancer as well as other hereditary and sporadic forms of RCC... - Salvage partial nephrectomy for hereditary renal cancer: feasibility and outcomesGennady Bratslavsky
Urologic Oncology Branch and Molecular Imaging Program PLC, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1107, USA
J Urol 179:67-70. 2008..We evaluated outcomes in patients who underwent third or fourth partial nephrectomies on the same kidney, which we call salvage partial nephrectomy... - Identification of the genes for kidney cancer: opportunity for disease-specific targeted therapeuticsW Marston Linehan
Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
Clin Cancer Res 13:671s-679s. 2007..These Mendelian single-gene syndromes provide a unique opportunity to evaluate the effectiveness of agents that target the VHL, c-Met, BHD, and fumarate hydratase pathways... - Repeat partial nephrectomy on the solitary kidney: surgical, functional and oncological outcomesNick W Liu
Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 1414, USA
J Urol 183:1719-24. 2010..We examined outcomes in patients with recurrent or de novo renal lesions treated with repeat partial nephrectomy on a solitary kidney... - Initial experience with robot assisted partial nephrectomy for multiple renal massesRonald Boris
Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1107, USA
J Urol 182:1280-6. 2009..We evaluated the feasibility of performing robot assisted partial nephrectomy in patients with multiple renal masses and examined the results of our initial experiences... - The clinical implications of the genetics of renal cell carcinomaInger Rosner
Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Urol Oncol 27:131-6. 2009..Advances in molecular therapeutics offer novel treatment options for patients with advanced disease... - Feasibility and outcomes of repeat partial nephrectomyAaron Johnson
Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1107, USA
J Urol 180:89-93; discussion 93. 2008..Management options for recurrent tumors include completion nephrectomy, ablation and repeat partial nephrectomy. We examine the feasibility and outcomes of repeat partial nephrectomy performed on the same renal unit... - Oncological outcomes of partial nephrectomy for multifocal renal cell carcinoma greater than 4 cmGopal N Gupta
Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
J Urol 184:59-63. 2010..We present oncological outcomes in patients with hereditary renal cell carcinoma treated with partial nephrectomy for multifocal solid tumors with the largest lesion greater than 4 cm... - Robotic partial nephrectomy for complex renal tumors: surgical techniqueCraig G Rogers
Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Eur Urol 53:514-21. 2008..We describe our technique, illustrated with video, of robotic partial nephrectomy for complex renal tumors, including hilar, endophytic, and multiple tumors... - Hereditary leiomyomatosis and renal cell cancer: a syndrome associated with an aggressive form of inherited renal cancerRobert L Grubb
Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
J Urol 177:2074-9; discussion 2079-80. 2007..We report the clinical characteristics and urological treatment of patients with hereditary leiomyomatosis and renal cell cancer associated renal tumors... - Genetic basis of kidney cancer: a model for developing molecular-targeted therapiesManish A Vira
Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892-1107, USA
BJU Int 99:1223-9. 2007 - UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancerYoufeng Yang
Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1107, Bldg 10 CRC, Room 1 5942, Bethesda, MD 20892 1107
Cancer Genet Cytogenet 196:45-55. 2010..This tumor model is the embodiment of the Warburg effect. UOK 262 provides a unique in vitro and in vivo preclinical model for studying the bioenergetics of the Warburg effect in human cancer... - Partial nephrectomy after previous radio frequency ablation: the National Cancer Institute experienceKeith J Kowalczyk
Department of Health and Human Services, Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 1107, USA
J Urol 182:2158-63. 2009..We report on the outcomes of partial nephrectomy on kidneys previously treated with radio frequency ablation... - Management of von Hippel-Lindau-associated kidney cancerRobert L Grubb
Urologic Oncology at the Urologic Oncology Branch of the National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Nat Clin Pract Urol 2:248-55. 2005..Elucidation of molecular pathways associated with VHL renal tumors may facilitate development of effective medical treatments for these lesions in the future... - Layered peptide array for multiplex immunohistochemistryGallya Gannot
Pathogenetics Unit, Advanced Technology Center, Laboratory of Pathology and Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892 4605, USA
J Mol Diagn 9:297-304. 2007..The experimental variability was 18%. Overall, the data suggest that iLPA technology will be a relatively simple and inexpensive method for molecular measurements from tissue sections... - Robotic partial nephrectomy for renal hilar tumors: a multi-institutional analysisCraig G Rogers
Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
J Urol 180:2353-6; discussion 2356. 2008..Tumors located adjacent to the renal hilum pose an additional challenge. We report a multi-institutional study of robotic partial nephrectomy for renal hilar tumors and describe our results... - Mechanisms of disease: hereditary leiomyomatosis and renal cell cancer--a distinct form of hereditary kidney cancerSunil Sudarshan
Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892 1107, USA
Nat Clin Pract Urol 4:104-10. 2007..Nevertheless, continued investigation of HLRCC should provide further insight into the mechanisms of kidney cancer development, and could potentially identify targets for new therapeutic approaches to RCC... - Assessment of critical renal ischemia with real-time infrared imagingAlexander M Gorbach
Laboratory of Bioengineering and Physical Science, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, Maryland, USA
J Surg Res 149:310-8. 2008..These temperature profiles then underwent spectral (frequency) analysis to assess their relationship to well-described oscillations of the microcirculation... - Mechanisms of disease: the role of heat-shock protein 90 in genitourinary malignancyJean Baptiste Lattouf
Urologic Oncology Branch, National Cancer Institute, Room 1 5942, Building 10 CRC, 9000 Rockville Pike, Bethesda, MD 20892, USA
Nat Clin Pract Urol 3:590-601. 2006..Studies being conducted in prostate cancer will hopefully help to define this potential application better... - A phase I feasibility study of an intraprostatic prostate-specific antigen-based vaccine in patients with prostate cancer with local failure after radiation therapy or clinical progression on androgen-deprivation therapy in the absence of local definitiveJean-Baptiste Lattouf
Urologic Oncology Branch, Clinical Center, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Clin Genitourin Cancer 5:89-92. 2006 - Concomitant surgery with laparoscopic live donor nephrectomyErnesto P Molmenti
Johns Hopkins University School of Medicine, Department of Surgery, Baltimore, MD, USA
Am J Transplant 3:219-23. 2003..This practice is beneficial to both the donor and the recipient, and is likely to become more commonplace with changing practice patterns involving donor evaluation and management...