P Pietrini

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Association between brain functional failure and dementia severity in Alzheimer's disease: resting versus stimulation PET study
    P Pietrini
    Laboratory of Neurosciences, National Institute on Aging, NIH, Bethesda, MD 20892, USA
    Am J Psychiatry 156:470-3. 1999
  2. ncbi request reprint Low glucose metabolism during brain stimulation in older Down's syndrome subjects at risk for Alzheimer's disease prior to dementia
    P Pietrini
    Laboratory of Neurosciences, National Institute on Aging, NIH, Bethesda, MD 20892, USA
    Am J Psychiatry 154:1063-9. 1997
  3. ncbi request reprint Frequency variation of a pattern-flash visual stimulus during PET differentially activates brain from striate through frontal cortex
    M J Mentis
    Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA
    Neuroimage 5:116-28. 1997
  4. ncbi request reprint Preferential metabolic involvement of visual cortical areas in a subtype of Alzheimer's disease: clinical implications
    P Pietrini
    Laboratory of Neurosciences, National Institute on Aging, Bethesda MD 20892, USA
    Am J Psychiatry 153:1261-8. 1996
  5. pmc Cholinergic stimulation alters performance and task-specific regional cerebral blood flow during working memory
    M L Furey
    Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 94:6512-6. 1997
  6. ncbi request reprint Increasing required neural response to expose abnormal brain function in mild versus moderate or severe Alzheimer's disease: PET study using parametric visual stimulation
    M J Mentis
    Laboratory of Neurosciences, National Institute on Aging, Bethesda, MD, USA
    Am J Psychiatry 155:785-94. 1998
  7. ncbi request reprint Cholinergic enhancement and increased selectivity of perceptual processing during working memory
    M L Furey
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
    Science 290:2315-9. 2000
  8. ncbi request reprint Cholinergic enhancement improves performance on working memory by modulating the functional activity in distinct brain regions: a positron emission tomography regional cerebral blood flow study in healthy humans
    M L Furey
    Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892 1366, USA
    Brain Res Bull 51:213-8. 2000
  9. ncbi request reprint Region-specific corpus callosum atrophy correlates with the regional pattern of cortical glucose metabolism in Alzheimer disease
    S J Teipel
    Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA
    Arch Neurol 56:467-73. 1999
  10. ncbi request reprint Time course of pharmacodynamic and pharmacokinetic effects of physostigmine assessed by functional brain imaging in humans
    M L Furey
    Laboratory of Neurosciences, National Institute on Aging, NIH, Bethesda, MD 20892, USA
    Pharmacol Biochem Behav 66:475-81. 2000

Detail Information

Publications13

  1. ncbi request reprint Association between brain functional failure and dementia severity in Alzheimer's disease: resting versus stimulation PET study
    P Pietrini
    Laboratory of Neurosciences, National Institute on Aging, NIH, Bethesda, MD 20892, USA
    Am J Psychiatry 156:470-3. 1999
    ..This study tested the hypothesis that regional cerebral glucose metabolism during neuronal activation is a more sensitive index of neuronal dysfunction and clinical severity in Alzheimer's disease than is glucose metabolism at rest...
  2. ncbi request reprint Low glucose metabolism during brain stimulation in older Down's syndrome subjects at risk for Alzheimer's disease prior to dementia
    P Pietrini
    Laboratory of Neurosciences, National Institute on Aging, NIH, Bethesda, MD 20892, USA
    Am J Psychiatry 154:1063-9. 1997
    ....
  3. ncbi request reprint Frequency variation of a pattern-flash visual stimulus during PET differentially activates brain from striate through frontal cortex
    M J Mentis
    Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA
    Neuroimage 5:116-28. 1997
    ..The reproducibility and systematically changing rCBF responses to this passive stimulus suggest that it could be successfully used as a disease probe to evaluate neural function and drug effects in cognitively impaired patients...
  4. ncbi request reprint Preferential metabolic involvement of visual cortical areas in a subtype of Alzheimer's disease: clinical implications
    P Pietrini
    Laboratory of Neurosciences, National Institute on Aging, Bethesda MD 20892, USA
    Am J Psychiatry 153:1261-8. 1996
    ..This study investigated whether specific cortical networks associated with visual processes are preferentially affected in this subgroup and determined the clinical implications of such abnormalities...
  5. pmc Cholinergic stimulation alters performance and task-specific regional cerebral blood flow during working memory
    M L Furey
    Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 94:6512-6. 1997
    ..These results suggest that enhancement of cholinergic function can improve processing efficiency and thus reduce the effort required to perform a WM task, and that activation of right prefrontal cortex is associated with task effort...
  6. ncbi request reprint Increasing required neural response to expose abnormal brain function in mild versus moderate or severe Alzheimer's disease: PET study using parametric visual stimulation
    M J Mentis
    Laboratory of Neurosciences, National Institute on Aging, Bethesda, MD, USA
    Am J Psychiatry 155:785-94. 1998
    ..The authors examined the interaction of Alzheimer's disease severity and visual stimulus complexity in relation to regional brain function...
  7. ncbi request reprint Cholinergic enhancement and increased selectivity of perceptual processing during working memory
    M L Furey
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
    Science 290:2315-9. 2000
    ....
  8. ncbi request reprint Cholinergic enhancement improves performance on working memory by modulating the functional activity in distinct brain regions: a positron emission tomography regional cerebral blood flow study in healthy humans
    M L Furey
    Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892 1366, USA
    Brain Res Bull 51:213-8. 2000
    ....
  9. ncbi request reprint Region-specific corpus callosum atrophy correlates with the regional pattern of cortical glucose metabolism in Alzheimer disease
    S J Teipel
    Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA
    Arch Neurol 56:467-73. 1999
    ..Atrophy of the corpus callosum as the major tract of intracortical connective fibers may reflect decreased cortical functional integration in AD...
  10. ncbi request reprint Time course of pharmacodynamic and pharmacokinetic effects of physostigmine assessed by functional brain imaging in humans
    M L Furey
    Laboratory of Neurosciences, National Institute on Aging, NIH, Bethesda, MD 20892, USA
    Pharmacol Biochem Behav 66:475-81. 2000
    ..More generally, we have demonstrated that experimental effects can vary with time, especially during the initial phases of a drug infusion, indicating that it is critical that these changes are controlled...
  11. ncbi request reprint The effect of brain atrophy on cerebral hypometabolism in the visual variant of Alzheimer disease
    A L Bokde
    Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA
    Arch Neurol 58:480-6. 2001
    ..The different patterns of hypometabolism indicate the differential development of the lesions between the AD and AD + VS groups...
  12. ncbi request reprint Conjoint and extended neural networks for the computation of speech codes: the neural basis of selective impairment in reading words and pseudowords
    B Xu
    Epilepsy Research Branch and Cognitive Neuroscience Section, NINDS, The National Institutes of Health, Bethesda, MD 20892, USA
    Cereb Cortex 11:267-77. 2001
    ..The implications of the results on theories and models of visual word reading and on selective reading dysfunctions after brain lesions are discussed...
  13. ncbi request reprint Distributed and overlapping representations of faces and objects in ventral temporal cortex
    J V Haxby
    Laboratory of Brain and Cognition, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Science 293:2425-30. 2001
    ..These results indicate that the representations of faces and objects in ventral temporal cortex are widely distributed and overlapping...