Karen W Phinney

Summary

Affiliation: National Institute of Standards and Technology
Country: USA

Publications

  1. ncbi request reprint Preparation and characterization of a suite of ephedra-containing standard reference materials
    Katherine E Sharpless
    National Institute of Standards and Technology, Analytical Chemistry Division, Gaithersburg, MD 20899 8390, USA
    J AOAC Int 89:1483-95. 2006
  2. pmc Development and certification of a standard reference material for vitamin D metabolites in human serum
    Karen W Phinney
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, United States
    Anal Chem 84:956-62. 2012
  3. ncbi request reprint Coupled achiral/chiral column techniques in subcritical fluid chromatography for the separation of chiral and nonchiral compounds
    K W Phinney
    Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 0001, USA
    Anal Chem 70:2331-5. 1998
  4. ncbi request reprint Enantioselective separations by packed column subcritical and supercritical fluid chromatography
    Karen W Phinney
    Analytical Chemistry Division, Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, MD 20899 8392, USA
    Anal Bioanal Chem 382:639-45. 2005
  5. ncbi request reprint Determination of ephedrine alkaloid stereoisomers in dietary supplements by capillary electrophoresis
    Karen W Phinney
    Analytical Chemistry Division, Chemical Science and Technology Laboratory, National Institute of Standards and Technology, 100 Bureau Drive, Stop 8392, Gaithersburg, MD 20899 8392, USA
    J Chromatogr A 1077:90-7. 2005
  6. ncbi request reprint Liquid chromatographic method for the determination of enantiomeric composition of amphetamine and methamphetamine in hair samples
    Karen W Phinney
    Analytical Chemistry Division, Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    Anal Bioanal Chem 378:144-9. 2004
  7. ncbi request reprint Enantioselective separations in capillary electrophoresis with dextran sulfate as the chiral selector
    Karen W Phinney
    Analytical Chemistry Division, Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    Anal Bioanal Chem 375:763-8. 2003
  8. ncbi request reprint Chiral recognition of functionalized cyclodextrins in capillary electrophoresis
    Karen W Phinney
    Analytical Chemistry Division, Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, MD 20899 8392, USA
    Electrophoresis 23:1308-13. 2002
  9. ncbi request reprint Chiral separations
    Karen W Phinney
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    Anal Bioanal Chem 372:22. 2002
  10. ncbi request reprint Development of a standard reference material for vitamin D in serum
    Karen W Phinney
    Analytical Chemistry Division, Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, MD, USA
    Am J Clin Nutr 88:511S-512S. 2008

Detail Information

Publications38

  1. ncbi request reprint Preparation and characterization of a suite of ephedra-containing standard reference materials
    Katherine E Sharpless
    National Institute of Standards and Technology, Analytical Chemistry Division, Gaithersburg, MD 20899 8390, USA
    J AOAC Int 89:1483-95. 2006
    ....
  2. pmc Development and certification of a standard reference material for vitamin D metabolites in human serum
    Karen W Phinney
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, United States
    Anal Chem 84:956-62. 2012
    ..Chromatographic resolution of the 3-epimer of 25(OH)D(3) proved to be essential for accurate determination of the metabolites...
  3. ncbi request reprint Coupled achiral/chiral column techniques in subcritical fluid chromatography for the separation of chiral and nonchiral compounds
    K W Phinney
    Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 0001, USA
    Anal Chem 70:2331-5. 1998
    ..The use of modified carbon dioxide eluents eliminated the mobile phase incompatibility problems associated with column coupling in liquid chromatography and incorporated the high efficiency of sub- and supercritical fluid chromatography...
  4. ncbi request reprint Enantioselective separations by packed column subcritical and supercritical fluid chromatography
    Karen W Phinney
    Analytical Chemistry Division, Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, MD 20899 8392, USA
    Anal Bioanal Chem 382:639-45. 2005
    ..This review will cover recent developments in the application of SFC to enantioseparations...
  5. ncbi request reprint Determination of ephedrine alkaloid stereoisomers in dietary supplements by capillary electrophoresis
    Karen W Phinney
    Analytical Chemistry Division, Chemical Science and Technology Laboratory, National Institute of Standards and Technology, 100 Bureau Drive, Stop 8392, Gaithersburg, MD 20899 8392, USA
    J Chromatogr A 1077:90-7. 2005
    ..The results obtained by the three CE methods were utilized for value assignment of the ephedrine alkaloid content of these five SRMs...
  6. ncbi request reprint Liquid chromatographic method for the determination of enantiomeric composition of amphetamine and methamphetamine in hair samples
    Karen W Phinney
    Analytical Chemistry Division, Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    Anal Bioanal Chem 378:144-9. 2004
    ..The methodology was evaluated with a Standard Reference Material that contained several drugs of abuse including amphetamine and methamphetamine...
  7. ncbi request reprint Enantioselective separations in capillary electrophoresis with dextran sulfate as the chiral selector
    Karen W Phinney
    Analytical Chemistry Division, Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    Anal Bioanal Chem 375:763-8. 2003
    ..Several factors, including hydrophobic, steric, and electrostatic interactions, appeared to play a role in the observed enantioseparations...
  8. ncbi request reprint Chiral recognition of functionalized cyclodextrins in capillary electrophoresis
    Karen W Phinney
    Analytical Chemistry Division, Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, MD 20899 8392, USA
    Electrophoresis 23:1308-13. 2002
    ..The results for the sulfated cyclodextrins also highlighted the importance of knowing the degree of substitution as well as the location of the substituents when comparing chiral selectors...
  9. ncbi request reprint Chiral separations
    Karen W Phinney
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    Anal Bioanal Chem 372:22. 2002
  10. ncbi request reprint Development of a standard reference material for vitamin D in serum
    Karen W Phinney
    Analytical Chemistry Division, Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, MD, USA
    Am J Clin Nutr 88:511S-512S. 2008
    ..Investigators will be able to use the standard reference material to validate new analytic methods as they are developed and to assign values to in-house quality-control materials...
  11. ncbi request reprint Determination of ephedrine alkaloids in dietary supplement standard reference materials
    Lane C Sander
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA
    Anal Chem 77:3101-12. 2005
    ..The SRMs are primarily intended for method validation and for use as control materials to support the analysis of dietary supplements and related botanical materials...
  12. doi request reprint Preparation and value assignment of standard reference material 968e fat-soluble vitamins, carotenoids, and cholesterol in human serum
    Jeanice B Thomas
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, MD 20899 8392, USA
    Anal Bioanal Chem 402:749-62. 2012
    ..The value assignment of the analytes in this SRM will help support measurement accuracy and traceability for laboratories performing health-related measurements in the clinical and nutritional communities...
  13. doi request reprint Isotope dilution liquid chromatography - mass spectrometry methods for fat- and water-soluble vitamins in nutritional formulations
    Karen W Phinney
    Analytical Chemistry Division, National Institute of Standards and Technology, 100 Bureau Drive, Gaithersburg, Maryland 20899, United States
    Anal Chem 83:92-8. 2011
    ..When possible, stable isotope labeled internal standards were employed for quantification...
  14. ncbi request reprint Preparation and characterization of standard reference material 1849 infant/adult nutritional formula
    Katherine E Sharpless
    National Institute of Standards and Technology, Analytical Chemistry Division, Gaithersburg, MD 20899 8390, USA
    J AOAC Int 93:1262-74. 2010
    ....
  15. doi request reprint Characterizing Vaccinium berry Standard Reference Materials by GC-MS using NIST spectral libraries
    Mark S Lowenthal
    Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, MD 20899 8392, USA
    Anal Bioanal Chem 405:4467-76. 2013
    ....
  16. doi request reprint Role of chromatography in the development of Standard Reference Materials for organic analysis
    Stephen A Wise
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    J Chromatogr A 1261:3-22. 2012
    ....
  17. ncbi request reprint Development and evaluation of a candidate reference measurement procedure for the determination of testosterone in human serum using isotope dilution liquid chromatography/tandem mass spectrometry
    Susan S C Tai
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, MD 20899 8392, USA
    Anal Bioanal Chem 388:1087-94. 2007
    ....
  18. doi request reprint Comparison of orthogonal liquid and gas chromatography-mass spectrometry platforms for the determination of amino acid concentrations in human plasma
    Elizabeth A McGaw
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, MD 20988 8392, USA
    J Chromatogr A 1217:5822-31. 2010
    ..3%. Certified mass fraction values for amino acids in NIST SRM 1950 will be established from statistically weighted means of all experimental results...
  19. ncbi request reprint Modifications to the NIST reference measurement procedure (RMP) for the determination of serum glucose by isotope dilution gas chromatography/mass spectrometry
    Jocelyn L Prendergast
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, MD 20899 8392, USA
    Anal Bioanal Chem 397:1779-85. 2010
    ....
  20. doi request reprint Universal proteolysis and MS(n) for N- and O-glycan branching analysis
    John E Schiel
    National Institute of Standards and Technology, Analytical Chemistry Division, 100 Bureau Dr, Stop 8392, Gaithersburg, MD 20899, USA
    J Mass Spectrom 48:533-8. 2013
    ..This methodology should be applicable to all glycoproteins and serve as an alternative to glycan release for MS(n) branching analysis. Published 2013. This article is a U.S. Government work and is in the public domain in the USA...
  21. doi request reprint Determination of fortified and endogenous folates in food-based Standard Reference Materials by liquid chromatography-tandem mass spectrometry
    Johanna E Camara
    Chemical Sciences Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    Anal Bioanal Chem 405:4561-8. 2013
    ..The values obtained for folic acid and 5-MTHF by LC-MS/MS will be incorporated into the final value assignments for all these food-based SRMs...
  22. doi request reprint Developing qualitative LC-MS methods for characterization of Vaccinium berry Standard Reference Materials
    Mark S Lowenthal
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, MD 20899 8392, USA
    Anal Bioanal Chem 405:4451-65. 2013
    ..An unbounded set of qualitative data about a biomaterial is a valuable complement to quantitative information traditionally provided in NIST Certificates of Analysis...
  23. doi request reprint LC-MS/MS biopharmaceutical glycoanalysis: identification of desirable reference material characteristics
    John E Schiel
    National Institute of Standards and Technology, Analytical Chemistry Division, Gaithersburg, MD 20899, USA
    Anal Bioanal Chem 403:2279-89. 2012
    ..The type and degree of information yielded by each method is assessed in an effort to identify desired reference material characteristics for improving biopharmaceutical glycoanalysis...
  24. doi request reprint Certification of drugs of abuse in a human serum standard reference material: SRM 1959
    Susan S C Tai
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    Anal Bioanal Chem 397:501-9. 2010
    ..1% to 1.1%. Agreement between the GC/MS and LC/MS methods ranged from 0.8% to 8.8%. The results from the methods were combined to obtain the certified concentrations and their expanded uncertainties...
  25. pmc Development and comparison of three liquid chromatography-atmospheric pressure chemical ionization/mass spectrometry methods for determining vitamin D metabolites in human serum
    Mary Bedner
    National Institute of Standards and Technology, Analytical Chemistry Division, Gaithersburg, MD 20899, USA
    J Chromatogr A 1240:132-9. 2012
    ..The 25(OH)D₃ was measured in SRM 909c using all three methods, and the results were compared...
  26. pmc Development of a candidate reference measurement procedure for the determination of 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2 in human serum using isotope-dilution liquid chromatography-tandem mass spectrometry
    Susan S C Tai
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 8392, USA
    Anal Chem 82:1942-8. 2010
    ..It can be used to provide an accuracy base to which clinical methods for 25(OH)D(3) and 25(OH)D(2) can be compared and that will serve as a standard of higher order for measurement traceability...
  27. doi request reprint Development and validation of a reference measurement procedure for certification of phenytoin, phenobarbital, lamotrigine, and topiramate in human serum using isotope-dilution liquid chromatography/tandem mass spectrometry
    Susan S C Tai
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, MD 20899 8392, USA
    Anal Bioanal Chem 401:1915-22. 2011
    ..3% to 2.4%. This LC-MS/MS RMP for PHT, PHB, LTG, and TPM in serum demonstrating good accuracy and precision can be used to assess the accuracy of routine methods used in clinical laboratories...
  28. doi request reprint Certification of NIST standard reference material 2389a, amino acids in 0.1 mol/L HCl--quantification by ID LC-MS/MS
    Mark S Lowenthal
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, MD 20899 8392, USA
    Anal Bioanal Chem 397:511-9. 2010
    ..This is the first time an ID LC-MS/MS methodology has been applied for quantifying amino acids in a NIST SRM material...
  29. doi request reprint Quantitative bottom-up proteomics depends on digestion conditions
    Mark S Lowenthal
    Biomolecular Measurement Division, National Institute of Standards and Technology, 100 Bureau Drive, Stop 8314, Gaithersburg, Maryland 20899 8315, United States
    Anal Chem 86:551-8. 2014
    ....
  30. doi request reprint Development of a standard reference material for metabolomics research
    Karen W Phinney
    Biomolecular Measurement Division, Chemical Sciences Division, and Biosystems and Biomaterials Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, United States
    Anal Chem 85:11732-8. 2013
    ..Value assignment measurements were performed by NIST and the Centers for Disease Control and Prevention (CDC). SRM 1950 is the first reference material developed specifically for metabolomics research. ..
  31. doi request reprint Metabolite Profiling of a NIST Standard Reference Material for Human Plasma (SRM 1950): GC-MS, LC-MS, NMR, and Clinical Laboratory Analyses, Libraries, and Web-Based Resources
    Yamil Simón-Manso
    Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 8380, United States
    Anal Chem 85:11725-31. 2013
    ..In-house computational tools have been developed or modified for MS data processing and interactive web display. All data and programs are freely available online at http://peptide.nist.gov/ and http://srmd.nist.gov/ . ..
  32. doi request reprint Determination of perfluorinated compounds in human plasma and serum Standard Reference Materials using independent analytical methods
    Jessica L Reiner
    Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, MD 20899 8392, USA
    Anal Bioanal Chem 401:2899-907. 2011
    ..Other PFCs were also detected in SRM 1950 and are reported. SRM 1950 can be used as a control material for human biomonitoring studies and as an aid to develop new measurement methods...
  33. ncbi request reprint Simultaneous concentration and separation of enantiomers with chiral temperature gradient focusing
    Karin M Balss
    National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA
    Anal Chem 76:7243-9. 2004
    ....
  34. doi request reprint Quantification of transferrin in human serum using both QconCAT and synthetic internal standards
    Tyler A Zimmerman
    Biomolecular Measurement Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899 United States
    Anal Chem 85:10362-8. 2013
    ..Using QconCAT and synthetic peptides in parallel gives a refined focus on method development, and the resulting methods should be applicable to other clinically relevant proteins. ..
  35. doi request reprint Mass spectrometry characterization for chemoenzymatic glycoprotein synthesis
    John E Schiel
    Analytical Chemistry Division, National Institute of Standards and Technology, 100 Bureau Drive, Stop 8392, Gaithersburg, MD 20899, USA
    J Mass Spectrom 46:649-57. 2011
    ..A well-defined glycoprotein standard containing a single glycan of known composition, linkage and stereochemistry would be of great value for the comparison and evaluation of glycoprotein analysis techniques...
  36. ncbi request reprint Chiral selectors from fruit: application of citrus pectins to enantiomer separations in capillary electrophoresis
    K W Phinney
    Chemical Science and Technology Laboratory, Analytical Chemistry Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    J Chromatogr A 857:285-93. 1999
    ..Changes in pH, chiral additive concentration and capillary type were studied in relation to chiral resolution. The effect of degree of esterification of pectin materials on chiral recognition was also evaluated...
  37. ncbi request reprint Quantitative determination of capsaicinoids by liquid chromatography-electrospray mass spectrometry
    Robert Q Thompson
    Department of Chemistry, Oberlin College, 119 Woodland Street, Oberlin, OH 44074, USA
    Anal Bioanal Chem 381:1441-51. 2005
    ..The major and minor capsaicinoids in a commercial plant extract and in chili pepper fruits were quantified...
  38. ncbi request reprint Reversed-phase liquid chromatography and argentation chromatography of the minor capsaicinoids
    Robert Q Thompson
    Department of Chemistry, Oberlin College, 119 Woodland Street, Oberlin, OH 44074, USA
    Anal Bioanal Chem 381:1432-40. 2005
    ..A mixed phenyl-cation-exchange stationary phase (charged with silver ion) enabled unique and useful separations of the capsaicinoids...