Emanuele Pelosi

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. doi request reprint Constitutively active Foxo3 in oocytes preserves ovarian reserve in mice
    Emanuele Pelosi
    Laboratory of Genetics, NIA NIH IRP, 251 Bayview Blvd, room 10B014, Baltimore, Maryland 21224, USA
    Nat Commun 4:1843. 2013
  2. pmc Germ cell formation from embryonic stem cells and the use of somatic cell nuclei in oocytes
    Emanuele Pelosi
    Laboratory of Genetics, National Institute on Aging NIH Intramural Research Program, Baltimore, Maryland, USA
    Ann N Y Acad Sci 1221:18-26. 2011
  3. pmc Foxl2 functions in sex determination and histogenesis throughout mouse ovary development
    Jose Elias Garcia-Ortiz
    Laboratory of Genetics, NIA NIH IRP, Baltimore, MD, USA
    BMC Dev Biol 9:36. 2009
  4. pmc Determination and stability of gonadal sex
    David Schlessinger
    Laboratory of Genetics, National Institute on Aging IRP, Baltimore, MD 21224, USA
    J Androl 31:16-25. 2010
  5. ncbi request reprint Loss of Wnt4 and Foxl2 leads to female-to-male sex reversal extending to germ cells
    Chris Ottolenghi
    Laboratory of Genetics, NIA NIH IRP, Baltimore, USA
    Hum Mol Genet 16:2795-804. 2007

Collaborators

Detail Information

Publications5

  1. doi request reprint Constitutively active Foxo3 in oocytes preserves ovarian reserve in mice
    Emanuele Pelosi
    Laboratory of Genetics, NIA NIH IRP, 251 Bayview Blvd, room 10B014, Baltimore, Maryland 21224, USA
    Nat Commun 4:1843. 2013
    ..This is the first gain-of-function model of augmented reproductive reserve in mice, thus emphasizing the role of Foxo3 as a guardian of the ovarian follicle pool in mammals and a potential determinant of the onset of menopause...
  2. pmc Germ cell formation from embryonic stem cells and the use of somatic cell nuclei in oocytes
    Emanuele Pelosi
    Laboratory of Genetics, National Institute on Aging NIH Intramural Research Program, Baltimore, Maryland, USA
    Ann N Y Acad Sci 1221:18-26. 2011
    ..Until full comprehension of these processes is obtained, clinical applications remain remote. Nevertheless, they represent promising tools in the future, enhancing methods of therapeutic cloning and infertility treatment...
  3. pmc Foxl2 functions in sex determination and histogenesis throughout mouse ovary development
    Jose Elias Garcia-Ortiz
    Laboratory of Genetics, NIA NIH IRP, Baltimore, MD, USA
    BMC Dev Biol 9:36. 2009
    ..g., Rspo1. Here we report expression profiling of mouse ovaries that lack Foxl2 alone or in combination with Wnt4 or Kit/c-Kit...
  4. pmc Determination and stability of gonadal sex
    David Schlessinger
    Laboratory of Genetics, National Institute on Aging IRP, Baltimore, MD 21224, USA
    J Androl 31:16-25. 2010
    ..A partial working model for somatic development and sex determination is presented in which Sox9 is a direct antagonist of Foxl2 in the supporting cell lineage...
  5. ncbi request reprint Loss of Wnt4 and Foxl2 leads to female-to-male sex reversal extending to germ cells
    Chris Ottolenghi
    Laboratory of Genetics, NIA NIH IRP, Baltimore, USA
    Hum Mol Genet 16:2795-804. 2007
    ..The data suggest that the relative autonomy of the action of Foxl2, Wnt4 and additional ovarian factor(s) in the mouse should facilitate the dissection of their respective contributions to female sex determination...