Rita Peila

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study
    Rita Peila
    Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA
    Diabetes 51:1256-62. 2002
  2. ncbi request reprint A TGF-beta1 polymorphism association with dementia and neuropathologies: the HAAS
    Rita Peila
    Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, National Institutes of Health, 7201 Wisconsin Avenue, Suite 3C 309, Bethesda, MD 20892 9205, USA
    Neurobiol Aging 28:1367-73. 2007
  3. ncbi request reprint Reducing the risk of dementia: efficacy of long-term treatment of hypertension
    Rita Peila
    Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA
    Stroke 37:1165-70. 2006
  4. ncbi request reprint Fasting insulin and incident dementia in an elderly population of Japanese-American men
    Rita Peila
    Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, National Institutes of Health, Room 3C 309 Gateway Building, 7201 Wisconsin Avenue, Bethesda, MD 20892, USA
    Neurology 63:228-33. 2004
  5. doi request reprint Enhanced risk for Alzheimer disease in persons with type 2 diabetes and APOE epsilon4: the Cardiovascular Health Study Cognition Study
    Fumiko Irie
    Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, 7201 Wisconsin Ave, Bethesda, MD, USA
    Arch Neurol 65:89-93. 2008
  6. ncbi request reprint Midlife pulse pressure and incidence of dementia: the Honolulu-Asia Aging Study
    Michael H Freitag
    Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA
    Stroke 37:33-7. 2006
  7. ncbi request reprint Insulin-degrading enzyme haplotypes affect insulin levels but not dementia risk
    Lauren Marlowe
    Laboratorie of Neurogenetics, Intramural Research Program, National Institute on Aging, Bethesda, MD 20892, USA
    Neurodegener Dis 3:320-6. 2006
  8. ncbi request reprint Is a fall just a fall: correlates of falling in healthy older persons. The Health, Aging and Body Composition Study
    Nathalie de Rekeneire
    Laboratory of Epidemiology, Demography and Biometry and Gerontology Research Center, National Institute on Aging, Bethesda, Maryland 20892, USA
    J Am Geriatr Soc 51:841-6. 2003
  9. ncbi request reprint Diabetes, hyperglycemia, and inflammation in older individuals: the health, aging and body composition study
    Nathalie de Rekeneire
    Laboratory of Epidemiology, National Institute on Aging, Bethesda, MD 20892 9205, USA
    Diabetes Care 29:1902-8. 2006
  10. pmc Linkage and association analyses of type 2 diabetes/impaired glucose metabolism and adiponectin serum levels in Japanese Americans from Hawaii
    Ilija P Kovac
    Department of Psychiatry, McGill University, Alan Memorial Institute, R and T Building, 1033 Pine Avenue West, Montreal H3A 1A1, Quebec, Canada
    Diabetes 56:537-40. 2007

Detail Information

Publications13

  1. ncbi request reprint Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study
    Rita Peila
    Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA
    Diabetes 51:1256-62. 2002
    ..6, 1.5-29.6). Type 2 diabetes is a risk factor for AD and VsD. The association between diabetes and AD is particularly strong among carriers of the APOE epsilon4 allele. The neuropathological data are consistent with the clinical results...
  2. ncbi request reprint A TGF-beta1 polymorphism association with dementia and neuropathologies: the HAAS
    Rita Peila
    Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, National Institutes of Health, 7201 Wisconsin Avenue, Suite 3C 309, Bethesda, MD 20892 9205, USA
    Neurobiol Aging 28:1367-73. 2007
    ..2-0.9). The CC genotype was associated with an increase risk of neocortical plaques (OR(CC)=4.34, CI: 1.6-11.8). These preliminary data suggest that the TGF genetic variability may be important in the risk of vascular related dementia...
  3. ncbi request reprint Reducing the risk of dementia: efficacy of long-term treatment of hypertension
    Rita Peila
    Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA
    Stroke 37:1165-70. 2006
    ..We evaluated the risk of dementia and cognitive decline associated with duration of antihypertensive treatment...
  4. ncbi request reprint Fasting insulin and incident dementia in an elderly population of Japanese-American men
    Rita Peila
    Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, National Institutes of Health, Room 3C 309 Gateway Building, 7201 Wisconsin Avenue, Bethesda, MD 20892, USA
    Neurology 63:228-33. 2004
    ..To evaluate the association of fasting insulin level to incident dementia in a cohort of elderly men...
  5. doi request reprint Enhanced risk for Alzheimer disease in persons with type 2 diabetes and APOE epsilon4: the Cardiovascular Health Study Cognition Study
    Fumiko Irie
    Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, 7201 Wisconsin Ave, Bethesda, MD, USA
    Arch Neurol 65:89-93. 2008
    ..Diabetes and the apolipoprotein E epsilon4 allele (APOE epsilon4) increase the risk for Alzheimer disease (AD). We hypothesize that APOE epsilon4 may modify the risk for AD in individuals with diabetes...
  6. ncbi request reprint Midlife pulse pressure and incidence of dementia: the Honolulu-Asia Aging Study
    Michael H Freitag
    Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA
    Stroke 37:33-7. 2006
    ..This study explores whether this association is attributable to the pulsatile, ie, pulse pressure (PP), or the nonpulsatile component of blood pressure (BP)...
  7. ncbi request reprint Insulin-degrading enzyme haplotypes affect insulin levels but not dementia risk
    Lauren Marlowe
    Laboratorie of Neurogenetics, Intramural Research Program, National Institute on Aging, Bethesda, MD 20892, USA
    Neurodegener Dis 3:320-6. 2006
    ..Insulin-degrading enzyme (IDE) polymorphism is hypothesized to regulate insulin levels as well as processes involved in neuronal compromise found in dementia...
  8. ncbi request reprint Is a fall just a fall: correlates of falling in healthy older persons. The Health, Aging and Body Composition Study
    Nathalie de Rekeneire
    Laboratory of Epidemiology, Demography and Biometry and Gerontology Research Center, National Institute on Aging, Bethesda, Maryland 20892, USA
    J Am Geriatr Soc 51:841-6. 2003
    ..To identify factors associated with falling in well-functioning older people...
  9. ncbi request reprint Diabetes, hyperglycemia, and inflammation in older individuals: the health, aging and body composition study
    Nathalie de Rekeneire
    Laboratory of Epidemiology, National Institute on Aging, Bethesda, MD 20892 9205, USA
    Diabetes Care 29:1902-8. 2006
    ..The objective of this study was to assess the association of inflammation with hyperglycemia (impaired fasting glucose [IFG]/impaired glucose tolerance [IGT]) and diabetes in older individuals...
  10. pmc Linkage and association analyses of type 2 diabetes/impaired glucose metabolism and adiponectin serum levels in Japanese Americans from Hawaii
    Ilija P Kovac
    Department of Psychiatry, McGill University, Alan Memorial Institute, R and T Building, 1033 Pine Avenue West, Montreal H3A 1A1, Quebec, Canada
    Diabetes 56:537-40. 2007
    ..2 cM. The present study was limited by relatively small sample size. Nevertheless, these results corroborate earlier studies, suggesting that further research is warranted in the candidate region approximately 30 cM on chromosome 14...
  11. ncbi request reprint A 32-year prospective study of change in body weight and incident dementia: the Honolulu-Asia Aging Study
    Robert Stewart
    Institute of Psychiatry, London, United Kingdom
    Arch Neurol 62:55-60. 2005
    ..The course of weight loss associated with dementia is unclear, particularly prior to and around the onset of the clinical syndrome...
  12. ncbi request reprint Association of interleukin-1 gene polymorphisms with dementia in a community-based sample: the Honolulu-Asia Aging Study
    Berran Yucesoy
    Toxicology and Molecular Biology Branch, Biostatistics Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA
    Neurobiol Aging 27:211-7. 2006
    ..There was no difference in the IL-1beta (+3953) frequency among the groups. Our results support the hypothesis that certain genetic variations contained within the IL-1 gene family contribute to the pathogenesis of dementia...
  13. pmc Cognitive impairment: an increasingly important complication of type 2 diabetes: the age, gene/environment susceptibility--Reykjavik study
    Jane S Saczynski
    Division of Geriatric Medicine, University of Massachusetts Medical School, Biotech Four, Suite 315, 377 Plantation Street, Worcester, MA 01605, USA
    Am J Epidemiol 168:1132-9. 2008
    ..01) and poorer memory performance (beta = -0.22; P < 0.05). Persons with type 2 diabetes have poorer cognitive performance than normoglycemics, particularly in PS. Those with undiagnosed diabetes have the lowest cognitive performance...