Fred M Parham

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Dose-response modeling of high-throughput screening data
    Fred Parham
    National Institutes of Health NIH National Institute of Environmental Health Sciences NIEHS, Research Triangle Park, North Carolina 27709, USA
    J Biomol Screen 14:1216-27. 2009
  2. pmc Choosing the right path: enhancement of biologically relevant sets of genes or proteins using pathway structure
    Reuben Thomas
    Environmental Systems Biology Group, Laboratory of Molecular Toxicology, National Institute of Environmental Health Sciences, RTP, NC 27709, USA
    Genome Biol 10:R44. 2009
  3. pmc Characterization of the proneural gene regulatory network during mouse telencephalon development
    Julia M Gohlke
    Environmental Systems Biology Group, Laboratory of Molecular Toxicology, National Institute of Environmental Health Sciences, RTP, NC 27709, USA
    BMC Biol 6:15. 2008
  4. ncbi request reprint A physiologically based pharmacokinetic model of p,p'-dichlorodiphenylsulfone
    Fred M Parham
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Appl Pharmacol 181:153-63. 2002

Collaborators

  • Ruili Huang
  • Julia M Gohlke
  • Reuben Thomas
  • Christopher J Portier
  • Geffrey F Stopper
  • Diogo S Castro
  • Gerard Gradwohl
  • Marjolein V Smith
  • Olivier Armant
  • Francois Guillemot
  • Celine Zimmer
  • Joel S Parker
  • Laurent Nguyen

Detail Information

Publications4

  1. pmc Dose-response modeling of high-throughput screening data
    Fred Parham
    National Institutes of Health NIH National Institute of Environmental Health Sciences NIEHS, Research Triangle Park, North Carolina 27709, USA
    J Biomol Screen 14:1216-27. 2009
    ..Various statistical tests for identifying significant concentration-response relationships and for addressing reproducibility are developed and presented...
  2. pmc Choosing the right path: enhancement of biologically relevant sets of genes or proteins using pathway structure
    Reuben Thomas
    Environmental Systems Biology Group, Laboratory of Molecular Toxicology, National Institute of Environmental Health Sciences, RTP, NC 27709, USA
    Genome Biol 10:R44. 2009
    ..The analysis provided demonstrates the method proposed is very competitive with the current approaches and also provides biologically relevant results...
  3. pmc Characterization of the proneural gene regulatory network during mouse telencephalon development
    Julia M Gohlke
    Environmental Systems Biology Group, Laboratory of Molecular Toxicology, National Institute of Environmental Health Sciences, RTP, NC 27709, USA
    BMC Biol 6:15. 2008
    ..The proneural proteins Mash1 and Ngn2 are key cell autonomous regulators of neurogenesis in the mammalian central nervous system, yet little is known about the molecular pathways regulated by these transcription factors...
  4. ncbi request reprint A physiologically based pharmacokinetic model of p,p'-dichlorodiphenylsulfone
    Fred M Parham
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Appl Pharmacol 181:153-63. 2002
    ..Because the data from mice are limited compared to those from rats, there is more confidence in the model's description of DDS kinetics in rats than in its description of kinetics in mice...