David M Panchision

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint The control of neural stem cells by morphogenic signals
    David M Panchision
    Laboratory of Molecular Biology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 36 Convent Drive MSC 4092, Bethesda, Maryland 20892 4092, USA
    Curr Opin Genet Dev 12:478-87. 2002
  2. pmc BMPs signal alternately through a SMAD or FRAP-STAT pathway to regulate fate choice in CNS stem cells
    Prithi Rajan
    Laboratory of Molecular Biology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    J Cell Biol 161:911-21. 2003
  3. ncbi request reprint BMP2 and FGF2 cooperate to induce neural-crest-like fates from fetal and adult CNS stem cells
    Martin H M Sailer
    Laboratory of Molecular Biology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    J Cell Sci 118:5849-60. 2005
  4. ncbi request reprint Complementary roles for histone deacetylases 1, 2, and 3 in differentiation of pluripotent stem cells
    Glen W Humphrey
    Laboratory of Molecular Growth Regulation, National Institute of Child Health and Human Development, Bethesda, MD 20892, USA
    Differentiation 76:348-56. 2008
  5. doi request reprint The role of oxygen in regulating neural stem cells in development and disease
    David M Panchision
    Division of Neuroscience and Basic Behavioral Science, National Institute of Mental Health, National Institutes of Health, 6001 Executive Blvd, MSC 9641, Bethesda, MD 20892 9641, USA
    J Cell Physiol 220:562-8. 2009
  6. pmc Meeting report: using stem cells for biological and therapeutics discovery in mental illness, April 2012
    David M Panchision
    Division of Neuroscience and Basic Behavioral Science, National Institute of Mental Health, Bethesda, MD, USA
    Stem Cells Transl Med 2:217-22. 2013
  7. doi request reprint Potency and fate specification in CNS stem cell populations in vitro
    Rea Ravin
    Laboratory of Molecular Biology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Cell Stem Cell 3:670-80. 2008

Collaborators

  • Daniel J Hoeppner
  • Prithi Rajan
  • Martin E Schwab
  • Ronald D G McKay
  • Rea Ravin
  • Glen W Humphrey
  • Martin H M Sailer
  • Raji Padmanabhan
  • David M Munno
  • Jim Sullivan
  • Tazuko Hirai
  • Christopher Athaide
  • Liran Carmel
  • Yong Hong Wang
  • Laura F Newell
  • Bruce H Howard
  • David L Levitt
  • Jennifer L Miller
  • Thomas G Hazel

Detail Information

Publications7

  1. ncbi request reprint The control of neural stem cells by morphogenic signals
    David M Panchision
    Laboratory of Molecular Biology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 36 Convent Drive MSC 4092, Bethesda, Maryland 20892 4092, USA
    Curr Opin Genet Dev 12:478-87. 2002
    ..Recent studies provide new insights on how morphogenic signals coordinate major stem cell decisions to regulate the size, shape and cellular diversity of the nervous system...
  2. pmc BMPs signal alternately through a SMAD or FRAP-STAT pathway to regulate fate choice in CNS stem cells
    Prithi Rajan
    Laboratory of Molecular Biology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    J Cell Biol 161:911-21. 2003
    ..Thus, glial differentiation by BMP4 occurs by a novel pathway mediated by FRAP and STAT proteins. These results suggest that a single ligand can regulate cell fate by activating distinct cytoplasmic signals...
  3. ncbi request reprint BMP2 and FGF2 cooperate to induce neural-crest-like fates from fetal and adult CNS stem cells
    Martin H M Sailer
    Laboratory of Molecular Biology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    J Cell Sci 118:5849-60. 2005
    ..This rapid and efficient induction of dorsal fates may allow identification of positional identity effectors that are co-regulated by FGF2 and BMP2...
  4. ncbi request reprint Complementary roles for histone deacetylases 1, 2, and 3 in differentiation of pluripotent stem cells
    Glen W Humphrey
    Laboratory of Molecular Growth Regulation, National Institute of Child Health and Human Development, Bethesda, MD 20892, USA
    Differentiation 76:348-56. 2008
    ..These results indicate that HDAC activity inhibits differentiation to oligodendrocytes, and that HDAC2 activity specifically inhibits differentiation to astrocytes, while HDAC1 activity is required for differentiation to neurons...
  5. doi request reprint The role of oxygen in regulating neural stem cells in development and disease
    David M Panchision
    Division of Neuroscience and Basic Behavioral Science, National Institute of Mental Health, National Institutes of Health, 6001 Executive Blvd, MSC 9641, Bethesda, MD 20892 9641, USA
    J Cell Physiol 220:562-8. 2009
    ..These findings suggest that O2 response is central to the normal architecture and dynamics of NSC regulation and in the etiology and treatment of brain diseases...
  6. pmc Meeting report: using stem cells for biological and therapeutics discovery in mental illness, April 2012
    David M Panchision
    Division of Neuroscience and Basic Behavioral Science, National Institute of Mental Health, Bethesda, MD, USA
    Stem Cells Transl Med 2:217-22. 2013
    ..A number of activities since the workshop have reflected the feedback from meeting participants...
  7. doi request reprint Potency and fate specification in CNS stem cell populations in vitro
    Rea Ravin
    Laboratory of Molecular Biology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Cell Stem Cell 3:670-80. 2008
    ..These results show how discrete cell types emerge from a multipotent cell and provide a strong basis for future studies to determine the molecular basis of fate specification...