Karin Pacheco

Summary

Affiliation: National Jewish Medical and Research Center
Country: USA

Publications

  1. pmc The influence of diesel exhaust particles on mononuclear phagocytic cell-derived cytokines: IL-10, TGF-beta and IL-1 beta
    K A Pacheco
    Department of Medicine, National Jewish Medical and Research Center, University of Colorado Health Sciences Center, Denver, Colorado 80206, USA
    Clin Exp Immunol 126:374-83. 2001
  2. ncbi request reprint Airborne endotoxin predicts symptoms in non-mouse-sensitized technicians and research scientists exposed to laboratory mice
    Karin A Pacheco
    Department of Medicine, Division of Environmental and Occupational Health Sciences, National Jewish Medical and Research Center, 1400 Jackson Street, Denver, CO 80206, USA
    Am J Respir Crit Care Med 167:983-90. 2003
  3. ncbi request reprint Characterization of endotoxin and mouse allergen exposures in mouse facilities and research laboratories
    Karin A Pacheco
    Department of Medicine, National Jewish Medical and Research Center, Denver, CO, USA
    Ann Occup Hyg 50:563-72. 2006
  4. ncbi request reprint New insights into laboratory animal exposures and allergic responses
    Karin A Pacheco
    Division of Environmental and Occupational Health Sciences, National Jewish Medical and Research Center, Denver, Colorado 80206, USA
    Curr Opin Allergy Clin Immunol 7:156-61. 2007
  5. doi request reprint Association of Toll-like receptor 4 alleles with symptoms and sensitization to laboratory animals
    Karin Pacheco
    Division of Environmental and Occupational Health Sciences, Department of Medicine, National Jewish Medical and Research Center, Denver, CO 80206, USA
    J Allergy Clin Immunol 122:896-902.e4. 2008
  6. ncbi request reprint Aerosolized sodium hypochlorite inhibits viability and allergenicity of mold on building materials
    John W Martyny
    National Jewish Medical and Research Center, Denver, CO 80206, USA
    J Allergy Clin Immunol 116:630-5. 2005
  7. doi request reprint RADS and its variants: asthma by another name
    Annyce Mayer
    Division of Environmental and Occupational Health Sciences, Department of Medicine, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, USA
    Immunol Allergy Clin North Am 33:79-93. 2013
  8. ncbi request reprint Of rats and men (and women)
    Karin A Pacheco
    Am J Respir Crit Care Med 174:1-2. 2006

Research Grants

  1. Study of Genetics, Endotoxin and Allergen (SAGE)
    Karin Pacheco; Fiscal Year: 2007

Detail Information

Publications8

  1. pmc The influence of diesel exhaust particles on mononuclear phagocytic cell-derived cytokines: IL-10, TGF-beta and IL-1 beta
    K A Pacheco
    Department of Medicine, National Jewish Medical and Research Center, University of Colorado Health Sciences Center, Denver, Colorado 80206, USA
    Clin Exp Immunol 126:374-83. 2001
    ..Pro-inflammatory cytokines and factors rise when IL-10 is inhibited, and are suppressed when IL-10 is stimulated. These results are duplicated with benzo[a]pyrene, suggesting that the PAH portion of the DEP is the active agent...
  2. ncbi request reprint Airborne endotoxin predicts symptoms in non-mouse-sensitized technicians and research scientists exposed to laboratory mice
    Karin A Pacheco
    Department of Medicine, Division of Environmental and Occupational Health Sciences, National Jewish Medical and Research Center, 1400 Jackson Street, Denver, CO 80206, USA
    Am J Respir Crit Care Med 167:983-90. 2003
    ..8, p = 0.003). We conclude that airborne endotoxin is associated with respiratory symptoms to mice in non-mouse-sensitized scientists and technicians...
  3. ncbi request reprint Characterization of endotoxin and mouse allergen exposures in mouse facilities and research laboratories
    Karin A Pacheco
    Department of Medicine, National Jewish Medical and Research Center, Denver, CO, USA
    Ann Occup Hyg 50:563-72. 2006
    ..Endotoxin and mouse allergen are derived from the same animal source, but have different physicochemical attributes. It is not known if airborne exposures to these agents are correlated in the laboratory animal workplace...
  4. ncbi request reprint New insights into laboratory animal exposures and allergic responses
    Karin A Pacheco
    Division of Environmental and Occupational Health Sciences, National Jewish Medical and Research Center, Denver, Colorado 80206, USA
    Curr Opin Allergy Clin Immunol 7:156-61. 2007
    ..To update the epidemiology of laboratory animal allergy, identify new exposures in the laboratory animal workplace, discuss complexities in the exposure-response relationship, and review the immunology of symptomatic and allergic responses...
  5. doi request reprint Association of Toll-like receptor 4 alleles with symptoms and sensitization to laboratory animals
    Karin Pacheco
    Division of Environmental and Occupational Health Sciences, Department of Medicine, National Jewish Medical and Research Center, Denver, CO 80206, USA
    J Allergy Clin Immunol 122:896-902.e4. 2008
    ..We hypothesized that functional genetic variants of Toll-like receptor 4 (TLR4), a key surface receptor for endotoxin, interface between worker and workplace and affect animal sensitization, symptoms, or both...
  6. ncbi request reprint Aerosolized sodium hypochlorite inhibits viability and allergenicity of mold on building materials
    John W Martyny
    National Jewish Medical and Research Center, Denver, CO 80206, USA
    J Allergy Clin Immunol 116:630-5. 2005
    ..Disinfectants that contain dilute sodium hypochlorite can kill mold and are practical to use. Whether they also inhibit mold allergy symptoms is unknown...
  7. doi request reprint RADS and its variants: asthma by another name
    Annyce Mayer
    Division of Environmental and Occupational Health Sciences, Department of Medicine, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, USA
    Immunol Allergy Clin North Am 33:79-93. 2013
    ....
  8. ncbi request reprint Of rats and men (and women)
    Karin A Pacheco
    Am J Respir Crit Care Med 174:1-2. 2006

Research Grants1

  1. Study of Genetics, Endotoxin and Allergen (SAGE)
    Karin Pacheco; Fiscal Year: 2007
    ....