Joao B Oliveira

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. doi request reprint Evaluation of IL-2-withdrawal-induced apoptosis in human T lymphocytes
    João Bosco Oliveira
    Pediatrics Department, Medical Institute Prof Fernando Figueira IMIP, Recife, PE, Brazil
    Methods Mol Biol 979:25-31. 2013
  2. pmc Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): report from the 2009 NIH International Workshop
    Joao B Oliveira
    Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA
    Blood 116:e35-40. 2010
  3. pmc Somatic KRAS mutations associated with a human nonmalignant syndrome of autoimmunity and abnormal leukocyte homeostasis
    Julie E Niemela
    Department of Laboratory Medicine, Warren Grant Magnuson Clinical Center, Bethesda, MD, USA
    Blood 117:2883-6. 2011
  4. doi request reprint Molecular- and flow cytometry-based diagnosis of primary immunodeficiency disorders
    Joao B Oliveira
    Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA
    Curr Allergy Asthma Rep 10:460-7. 2010
  5. pmc Critical role for BIM in T cell receptor restimulation-induced death
    Andrew L Snow
    Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, MD 20892 1508, USA
    Biol Direct 3:34. 2008
  6. ncbi request reprint Autoimmune lymphoproliferative syndrome
    Thomas A Fleisher
    Immunology Service, Department of Laboratory Medicine, Clinical Center, National Institutes of Health, DHHS, Bethesda, MD, USA
    Isr Med Assoc J 7:758-61. 2005
  7. pmc FAS haploinsufficiency is a common disease mechanism in the human autoimmune lymphoproliferative syndrome
    Hye Sun Kuehn
    Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, MD 20814, USA
    J Immunol 186:6035-43. 2011
  8. doi request reprint Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency
    Carrie L Lucas
    1 Molecular Development of the Immune System Section, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA 2
    Nat Immunol 15:88-97. 2014
  9. doi request reprint Applications of flow cytometry for the study of primary immune deficiencies
    Joao B Oliveira
    Immunology Service, Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland 20892 1508, USA
    Curr Opin Allergy Clin Immunol 8:499-509. 2008
  10. pmc Loss-of-function of the protein kinase C δ (PKCδ) causes a B-cell lymphoproliferative syndrome in humans
    Hye Sun Kuehn
    Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, MD, USA
    Blood 121:3117-25. 2013

Collaborators

Detail Information

Publications18

  1. doi request reprint Evaluation of IL-2-withdrawal-induced apoptosis in human T lymphocytes
    João Bosco Oliveira
    Pediatrics Department, Medical Institute Prof Fernando Figueira IMIP, Recife, PE, Brazil
    Methods Mol Biol 979:25-31. 2013
    ..We describe here how to evaluate the integrity of the intrinsic pathway of lymphocyte apoptosis triggered by starvation for IL-2 or other survival cytokines...
  2. pmc Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): report from the 2009 NIH International Workshop
    Joao B Oliveira
    Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA
    Blood 116:e35-40. 2010
    ..It is hoped that harmonizing the diagnosis and classification of ALPS will foster collaborative research and better understanding of the pathogenesis of autoimmune cytopenias and B-cell lymphomas...
  3. pmc Somatic KRAS mutations associated with a human nonmalignant syndrome of autoimmunity and abnormal leukocyte homeostasis
    Julie E Niemela
    Department of Laboratory Medicine, Warren Grant Magnuson Clinical Center, Bethesda, MD, USA
    Blood 117:2883-6. 2011
    ..We suggest the use of the term RAS-associated autoimmune leukoproliferative disease to differentiate this disorder from autoimmune lymphoproliferative syndrome...
  4. doi request reprint Molecular- and flow cytometry-based diagnosis of primary immunodeficiency disorders
    Joao B Oliveira
    Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA
    Curr Allergy Asthma Rep 10:460-7. 2010
    ..We discuss here advances in flow cytometry and molecular techniques applied to the study of primary immunodeficiencies...
  5. pmc Critical role for BIM in T cell receptor restimulation-induced death
    Andrew L Snow
    Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, MD 20892 1508, USA
    Biol Direct 3:34. 2008
    ....
  6. ncbi request reprint Autoimmune lymphoproliferative syndrome
    Thomas A Fleisher
    Immunology Service, Department of Laboratory Medicine, Clinical Center, National Institutes of Health, DHHS, Bethesda, MD, USA
    Isr Med Assoc J 7:758-61. 2005
  7. pmc FAS haploinsufficiency is a common disease mechanism in the human autoimmune lymphoproliferative syndrome
    Hye Sun Kuehn
    Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, MD 20814, USA
    J Immunol 186:6035-43. 2011
    ..The apoptosis defect could be corrected by FAS overexpression in vitro. Our findings define haploinsufficiency as a common disease mechanism in ALPS patients with extracellular FAS mutations...
  8. doi request reprint Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency
    Carrie L Lucas
    1 Molecular Development of the Immune System Section, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA 2
    Nat Immunol 15:88-97. 2014
    ..Notably, treatment with rapamycin to inhibit mTOR activity in vivo partially restored the abundance of naive T cells, largely 'rescued' the in vitro T cell defects and improved the clinical course. ..
  9. doi request reprint Applications of flow cytometry for the study of primary immune deficiencies
    Joao B Oliveira
    Immunology Service, Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland 20892 1508, USA
    Curr Opin Allergy Clin Immunol 8:499-509. 2008
    ..This review focuses on the current applications of flow cytometry for the diagnosis and evaluation of primary immune deficiencies (PIDs)...
  10. pmc Loss-of-function of the protein kinase C δ (PKCδ) causes a B-cell lymphoproliferative syndrome in humans
    Hye Sun Kuehn
    Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, MD, USA
    Blood 121:3117-25. 2013
    ..In summary, homozygous PRKCD mutation results in B-cell hyperproliferation and defective apoptosis with consequent lymphocyte accumulation and autoantibody production in humans, and disrupts natural killer cell function...
  11. ncbi request reprint Autoimmune lymphoproliferative syndrome
    Joao B Oliveira
    Department of Laboratory Medicine, Clinical Center, National Institutes of Health, DHHS, Bethesda, Maryland 20892, USA
    Curr Opin Allergy Clin Immunol 4:497-503. 2004
    ..In this review we summarize current information regarding the diagnosis, management and underlying molecular basis of the syndrome...
  12. pmc Laboratory evaluation of primary immunodeficiencies
    Joao B Oliveira
    Department of Laboratory Medicine, Clinical Center, National Institutes of Health, USA
    J Allergy Clin Immunol 125:S297-305. 2010
    ..In this article the authors describe a general approach for the investigation of the most common primary immunodeficiencies, outlining the typical clinical symptoms and most appropriate laboratory investigations...
  13. doi request reprint Autoimmunity in hyper-IgM syndrome
    Adriana A Jesus
    Pediatric Rheumatology Unit, Pediatrics Department, Universidade de Sao Paulo, Av Dr Enéas Carvalho de Aguiar 500 IMT Bldg II 3rd floor, Sao Paulo, Sao Paulo 054030 000, Brazil
    J Clin Immunol 28:S62-6. 2008
    ..HIGM can thus be associated with an impairment of both B-cell and T-cell activation...
  14. doi request reprint TNF receptor-associated periodic syndrome (TRAPS): description of a novel TNFRSF1A mutation and response to etanercept
    Adriana A Jesus
    Pediatric Rheumatology Unit, Pediatrics Department, University of Sao Paulo, Av Dr Eneas de Carvalho Aguiar, 647, 05403 900, Sao Paulo, SP, Brazil
    Eur J Pediatr 167:1421-5. 2008
    ....
  15. pmc CD40 agonist antibody mediated improvement of chronic Cryptosporidium infection in patients with X-linked hyper IgM syndrome
    Xiying Fan
    Laboratory of Host Defenses, National Institutes of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA
    Clin Immunol 143:152-61. 2012
    ..This study demonstrates that CP-870,893 suppressed oocysts shedding in XHM patients with biliary cryptosporidiosis. The continued study of CD40 agonists in XHM is warranted...
  16. pmc Anti-cytokine autoantibodies are associated with opportunistic infection in patients with thymic neoplasia
    Peter D Burbelo
    Neurobiology and Pain Therapeutics, Laboratory of Sensory Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA
    Blood 116:4848-58. 2010
    ..This study was registered at http://clinicaltrials.gov as NCT00001355...
  17. pmc NRAS mutation causes a human autoimmune lymphoproliferative syndrome
    Joao B Oliveira
    Department of Laboratory Medicine, Clinical Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 104:8953-8. 2007
    ..Our observations on the effects of NRAS activation indicate that RAS-inactivating drugs, such as farnesyltransferase inhibitors should be examined in human autoimmune and lymphocyte homeostasis disorders...
  18. pmc ALPS-ten lessons from an international workshop on a genetic disease of apoptosis
    Michael J Lenardo
    Molecular Development Section, Laboratory of Immunology, NIAID, National Institutes of Health, Bethesda, MD 20892, USA
    Immunity 32:291-5. 2010
    ..Their discussions yielded ten broad messages applicable to genetic and immunological investigations of human disease...