K Olden

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Genomics: implications for toxicology
    K Olden
    Department of Health and Human Services, National Institute of Environmental Health Sciences and National Toxicology Program, National Institutes of Health, Research Triangle Park, NC 27709, USA
    Mutat Res 473:3-10. 2001
  2. ncbi Toxicogenomics--a new systems toxicology approach to understanding of gene-environment interactions
    Kenneth Olden
    Cell Adhesion and Metastasis Section, Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    Ann N Y Acad Sci 1076:703-6. 2006
  3. ncbi Genomics in environmental health research--opportunities and challenges
    Kenneth Olden
    Department of Health and Human Services, National Institute of Environmental Health Sciences and the National Toxicology Program, National Institutes of Health, P O Box 12233, Research Triangle Park, NC 27709 USA
    Toxicology 198:19-24. 2004
  4. ncbi Commentary: From phenotype, to genotype, to gene-environment interaction and risk for complex diseases
    Kenneth Olden
    Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences/NIH, Research Triangle Park, NC 27705, USA
    Int J Epidemiol 36:18-20. 2007
  5. ncbi Health-related disparities: influence of environmental factors
    Kenneth Olden
    National Institute of Environmental Health Sciences, United States Department of Health and Human Services, National Institutes of Health, PO Box 12233, Research Triangle Park, NC 27709, USA
    Med Clin North Am 89:721-38. 2005
  6. ncbi Environmental health and genomics: visions and implications
    K Olden
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Nat Rev Genet 1:149-53. 2000
  7. ncbi A bold new direction for environmental health research
    K Olden
    National Institute of Environmental Health Sciences and the National Toxicology Program, Research Triangle Park, NC, USA
    Am J Public Health 91:1964-7. 2001
  8. ncbi Partnership for Parkinson's disease research: patient-researcher-clinician-sponsor
    Kenneth Olden
    National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Neurotoxicology 23:451-6. 2002
  9. ncbi Gene-environment interactions in the development of complex disease phenotypes
    Rosemarie G Ramos
    Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, MD NH04, Box 12233, Research Triangle Park, North Carolina 27709, USA
    Int J Environ Res Public Health 5:4-11. 2008
  10. ncbi Multidisciplinary research: strategies for assessing chemical mixtures to reduce risk of exposure and disease
    William A Suk
    National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    Int J Occup Med Environ Health 17:103-10. 2004

Collaborators

Detail Information

Publications26

  1. ncbi Genomics: implications for toxicology
    K Olden
    Department of Health and Human Services, National Institute of Environmental Health Sciences and National Toxicology Program, National Institutes of Health, Research Triangle Park, NC 27709, USA
    Mutat Res 473:3-10. 2001
    ..These studies will change radically the practice of public health and clinical medicine, and the approach to the development of pharmaceuticals...
  2. ncbi Toxicogenomics--a new systems toxicology approach to understanding of gene-environment interactions
    Kenneth Olden
    Cell Adhesion and Metastasis Section, Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    Ann N Y Acad Sci 1076:703-6. 2006
    ..In my opinion, the development of the field of toxicogenomics will provide powerful and relatively inexpensive tools to identify biomarkers and to relate exposure and biological events during disease progression...
  3. ncbi Genomics in environmental health research--opportunities and challenges
    Kenneth Olden
    Department of Health and Human Services, National Institute of Environmental Health Sciences and the National Toxicology Program, National Institutes of Health, P O Box 12233, Research Triangle Park, NC 27709 USA
    Toxicology 198:19-24. 2004
    ..But, before embracing the 'omics' technologies as the 'be all-end all;' they need to be validated for their predictive capacities in large-scale multi-institutional studies, such as those described in this article...
  4. ncbi Commentary: From phenotype, to genotype, to gene-environment interaction and risk for complex diseases
    Kenneth Olden
    Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences/NIH, Research Triangle Park, NC 27705, USA
    Int J Epidemiol 36:18-20. 2007
  5. ncbi Health-related disparities: influence of environmental factors
    Kenneth Olden
    National Institute of Environmental Health Sciences, United States Department of Health and Human Services, National Institutes of Health, PO Box 12233, Research Triangle Park, NC 27709, USA
    Med Clin North Am 89:721-38. 2005
    ....
  6. ncbi Environmental health and genomics: visions and implications
    K Olden
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Nat Rev Genet 1:149-53. 2000
    ..Here we discuss the goals of the Environmental Genome Project, its implications and, in particular, its potential effect on our ability to assess human disease risk in the future...
  7. ncbi A bold new direction for environmental health research
    K Olden
    National Institute of Environmental Health Sciences and the National Toxicology Program, Research Triangle Park, NC, USA
    Am J Public Health 91:1964-7. 2001
    ..New initiatives of the National Institute of Environmental Health Sciences, including the Environmental Genome Project and the Toxicogenomics Center, are discussed...
  8. ncbi Partnership for Parkinson's disease research: patient-researcher-clinician-sponsor
    Kenneth Olden
    National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Neurotoxicology 23:451-6. 2002
    ..The NIEHS will also continue to explore ways to promote more mechanism-based research to understand putative environmental triggers for PD in concert with defined genetic susceptibilities...
  9. ncbi Gene-environment interactions in the development of complex disease phenotypes
    Rosemarie G Ramos
    Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, MD NH04, Box 12233, Research Triangle Park, North Carolina 27709, USA
    Int J Environ Res Public Health 5:4-11. 2008
    ..Ultimately, it is this knowledge that will be used to guide agencies such as the U.S. Department of Health and Human Services in decisions regarding biomedical research funding and policy...
  10. ncbi Multidisciplinary research: strategies for assessing chemical mixtures to reduce risk of exposure and disease
    William A Suk
    National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    Int J Occup Med Environ Health 17:103-10. 2004
    ..Integrating these approaches are necessary to advance understanding of the health relevance of exposure to mixtures...
  11. ncbi The prevalence of metabolic syndrome among US women of childbearing age
    Rosemarie G Ramos
    Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    Am J Public Health 98:1122-7. 2008
    ....
  12. ncbi Strategies for setting a national research agenda that is responsive to community needs
    Liam R O'Fallon
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 111:1855-60. 2003
    ....
  13. ncbi The impact of new technologies on human population studies
    Michael D Waters
    National Center for Toxicogenomics, 111 Alexander Drive, P O Box 12233, MD F1 05, Research Triangle Park, NC 27709 2233, USA
    Mutat Res 544:349-60. 2003
    ..This knowledge can be used to protect susceptible individuals from disease and to reduce adverse exposure and environmentally induced disease...
  14. ncbi Environmental health moves into the 21st century
    Christopher Schonwalder
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709 2233, USA
    Int J Hyg Environ Health 206:263-7. 2003
    ..But the comfort of 100% certainty will not be available in the foreseeable future, leaving us with the challenge of designing relevant experiments and test systems upon which to base "logical" policy in risk management...
  15. ncbi Systems toxicology and the Chemical Effects in Biological Systems (CEBS) knowledge base
    Michael Waters
    National Center for Toxicogenomics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    EHP Toxicogenomics 111:15-28. 2003
    ..The CEBS development effort will span a decade or more...
  16. ncbi Toxicogenomic approach for assessing toxicant-related disease
    Michael D Waters
    National Center for Toxigenomics, National Institute of Environmental Health Sciences, P O Box 12233, MD F1 05, 111 Alexander Drive, Research Triangle Park, NC 27709 2233, USA
    Mutat Res 544:415-24. 2003
    ....
  17. ncbi The Environmental Genome Project: phase I and beyond
    Samuel H Wilson
    National Institute of Environmental Health Sciences, National Institutes of Health, 111 T.W. Alexander Drive Research Triangle Park, NC 27709-2233
    Mol Interv 4:147-56. 2004
    ....
  18. ncbi The second National Institutes of Health International Congress on advances in uterine leiomyoma research: conference summary and future recommendations
    Darlene Dixon
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA
    Fertil Steril 86:800-6. 2006
    ..This document summarizes this exchange and outlines research needs and recommendations for future research directions...
  19. ncbi Toxicogenomics through the eyes of informatics: conference overview and recommendations
    Kenneth Olden
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA
    Environ Health Perspect 112:805-7. 2004
    ..In conclusion this report discusses toxicogenomics as related to environmental agents, cell-chemical reactions, and gene-environment interactions...
  20. ncbi Chemical mixtures research: significance and future perspectives
    William A Suk
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    Environ Health Perspect 110:891-2. 2002
  21. ncbi 15-lipoxygenase-1 activates tumor suppressor p53 independent of enzymatic activity
    Hong Zhu
    Eicosanoid Biochemistry Section, Laboratory of Molecular Carcinogenesis, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, NC, USA
    Int J Cancer 123:2741-9. 2008
    ....
  22. ncbi Olden times: looking back on a career at the NIEHS
    David Brown
    Environ Health Perspect 112:A598-9. 2004
  23. ncbi Relevance of the National Institute of Health Roadmap initiatives to the field of environmental health
    Kenneth Olden
    Environ Health Perspect 112:A145-6. 2004
  24. ncbi Kenneth Olden, master fencer
    Valerie J Brown
    Am J Public Health 94:1905-7. 2004
  25. ncbi New opportunities in toxicology in the post-genomic era
    Kenneth Olden
    Drug Discov Today 7:273-6. 2002
  26. ncbi Community-based participatory research: a vehicle to promote public engagement for environmental health in China
    Robbie Ali
    Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Environ Health Perspect 116:1281-4. 2008
    ..Chinese government leaders have recently emphasized the need for better environmental protection practices along with interventions involving strong public participation...