Terrance P O'Hanlon

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint HLA polymorphisms in African Americans with idiopathic inflammatory myopathy: allelic profiles distinguish patients with different clinical phenotypes and myositis autoantibodies
    Terrance P O'Hanlon
    National Institute of Environmental Health Sciences, Bethesda, Maryland 20892, USA
    Arthritis Rheum 54:3670-81. 2006
  2. pmc Immunoglobulin gene polymorphisms are susceptibility factors in clinical and autoantibody subgroups of the idiopathic inflammatory myopathies
    Terrance P O'Hanlon
    National Institute of Environmental Health Sciences, NIH, Bethesda, Maryland 20892, USA
    Arthritis Rheum 58:3239-46. 2008
  3. ncbi request reprint Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1 and -DQA1 allelic profiles and motifs define clinicopathologic groups in caucasians
    Terrance P O'Hanlon
    National Institute of Environmental Health Sciences, Rockville, MD 20892 0958, USA
    Medicine (Baltimore) 84:338-49. 2005
  4. pmc Gene expression profiles from discordant monozygotic twins suggest that molecular pathways are shared among multiple systemic autoimmune diseases
    Terrance P O'Hanlon
    Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Arthritis Res Ther 13:R69. 2011
  5. ncbi request reprint Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European American patients with different myositis autoantibodies
    Terrance P O'Hanlon
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Medicine (Baltimore) 85:111-27. 2006
  6. ncbi request reprint Genetic risk and protective factors for the idiopathic inflammatory myopathies
    Terrance P O'Hanlon
    National Institute of Environmental Health Sciences, National Institutes of Health, Room 1W101, Bethesda, MD 20892, USA
    Curr Rheumatol Rep 11:287-94. 2009
  7. pmc Immunogenetic risk and protective factors for juvenile dermatomyositis in Caucasians
    Gulnara Mamyrova
    National Institute of Environmental Health Sciences, NIH, Bethesda, Maryland 20892, USA
    Arthritis Rheum 54:3979-87. 2006
  8. pmc Cytokine gene polymorphisms as risk and severity factors for juvenile dermatomyositis
    Gulnara Mamyrova
    National Institute of Environmental Health Sciences, NIH, Bethesda, Maryland 20892 1301, USA
    Arthritis Rheum 58:3941-50. 2008
  9. ncbi request reprint Differences in idiopathic inflammatory myopathy phenotypes and genotypes between Mesoamerican Mestizos and North American Caucasians: ethnogeographic influences in the genetics and clinical expression of myositis
    Ejaz A Shamim
    Center for Biologics Evaluation and Research, FDA, Bethesda, Maryland, USA
    Arthritis Rheum 46:1885-93. 2002
  10. pmc Predictors of acquired lipodystrophy in juvenile-onset dermatomyositis and a gradient of severity
    April Bingham
    From Office of Clinical Research, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland 20892 1301, USA
    Medicine (Baltimore) 87:70-86. 2008

Detail Information

Publications35

  1. ncbi request reprint HLA polymorphisms in African Americans with idiopathic inflammatory myopathy: allelic profiles distinguish patients with different clinical phenotypes and myositis autoantibodies
    Terrance P O'Hanlon
    National Institute of Environmental Health Sciences, Bethesda, Maryland 20892, USA
    Arthritis Rheum 54:3670-81. 2006
    ..To investigate possible associations of HLA polymorphisms with idiopathic inflammatory myopathy (IIM) in African Americans, and to compare this with HLA associations in European American IIM patients with IIM...
  2. pmc Immunoglobulin gene polymorphisms are susceptibility factors in clinical and autoantibody subgroups of the idiopathic inflammatory myopathies
    Terrance P O'Hanlon
    National Institute of Environmental Health Sciences, NIH, Bethesda, Maryland 20892, USA
    Arthritis Rheum 58:3239-46. 2008
    ..To investigate possible associations of GM and KM markers with adult and juvenile forms of the idiopathic inflammatory myopathies (IIMs) in Caucasian and African American patients...
  3. ncbi request reprint Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1 and -DQA1 allelic profiles and motifs define clinicopathologic groups in caucasians
    Terrance P O'Hanlon
    National Institute of Environmental Health Sciences, Rockville, MD 20892 0958, USA
    Medicine (Baltimore) 84:338-49. 2005
    ..These variations in associated HLA polymorphisms may reflect responses to unique environmental triggers resulting in the tissue pathospecificity and distinct clinicopathologic syndromes of the IIM...
  4. pmc Gene expression profiles from discordant monozygotic twins suggest that molecular pathways are shared among multiple systemic autoimmune diseases
    Terrance P O'Hanlon
    Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Arthritis Res Ther 13:R69. 2011
    ..The objective of this study is to determine if multiple systemic autoimmune diseases (SAID) share gene expression pathways that could provide insights into pathogenic mechanisms common to these disorders...
  5. ncbi request reprint Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European American patients with different myositis autoantibodies
    Terrance P O'Hanlon
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Medicine (Baltimore) 85:111-27. 2006
    ....
  6. ncbi request reprint Genetic risk and protective factors for the idiopathic inflammatory myopathies
    Terrance P O'Hanlon
    National Institute of Environmental Health Sciences, National Institutes of Health, Room 1W101, Bethesda, MD 20892, USA
    Curr Rheumatol Rep 11:287-94. 2009
    ....
  7. pmc Immunogenetic risk and protective factors for juvenile dermatomyositis in Caucasians
    Gulnara Mamyrova
    National Institute of Environmental Health Sciences, NIH, Bethesda, Maryland 20892, USA
    Arthritis Rheum 54:3979-87. 2006
    ....
  8. pmc Cytokine gene polymorphisms as risk and severity factors for juvenile dermatomyositis
    Gulnara Mamyrova
    National Institute of Environmental Health Sciences, NIH, Bethesda, Maryland 20892 1301, USA
    Arthritis Rheum 58:3941-50. 2008
    ....
  9. ncbi request reprint Differences in idiopathic inflammatory myopathy phenotypes and genotypes between Mesoamerican Mestizos and North American Caucasians: ethnogeographic influences in the genetics and clinical expression of myositis
    Ejaz A Shamim
    Center for Biologics Evaluation and Research, FDA, Bethesda, Maryland, USA
    Arthritis Rheum 46:1885-93. 2002
    ....
  10. pmc Predictors of acquired lipodystrophy in juvenile-onset dermatomyositis and a gradient of severity
    April Bingham
    From Office of Clinical Research, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland 20892 1301, USA
    Medicine (Baltimore) 87:70-86. 2008
    ..Further study is warranted to investigate the pathogenesis of acquired LD in patients with DM...
  11. pmc Genome-wide association study of dermatomyositis reveals genetic overlap with other autoimmune disorders
    Frederick W Miller
    National Institute of Environmental Health Sciences, NIH, Bethesda, Maryland
    Arthritis Rheum 65:3239-47. 2013
    ..To identify new genetic associations with juvenile and adult dermatomyositis (DM)...
  12. pmc Ultraviolet radiation intensity predicts the relative distribution of dermatomyositis and anti-Mi-2 autoantibodies in women
    Lori A Love
    Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA
    Arthritis Rheum 60:2499-504. 2009
    ....
  13. ncbi request reprint Global surface ultraviolet radiation intensity may modulate the clinical and immunologic expression of autoimmune muscle disease
    Satoshi Okada
    Center for Biologics Evaluation and Research, Food and Drug Administration NIH, Bethesda, MD, USA
    Arthritis Rheum 48:2285-93. 2003
    ..To determine if geoclimatic factors may influence the nature and frequency of dermatomyositis (DM), polymyositis, and associated autoantibodies around the world...
  14. pmc Plasma proteomic profiles from disease-discordant monozygotic twins suggest that molecular pathways are shared in multiple systemic autoimmune diseases
    Terrance P O'Hanlon
    Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, DHHS, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Arthritis Res Ther 13:R181. 2011
    ..We assessed plasma proteomic profiles among different SAID for evidence of common molecular pathways that could provide insights into pathogenic mechanisms shared by these diseases...
  15. pmc Environmental factors preceding illness onset differ in phenotypes of the juvenile idiopathic inflammatory myopathies
    Lisa G Rider
    Environmental Autoimmunity Group, National Institute of Environmental Sciences, National Institutes of Health, DHHS, Clinical Research Center Room 4 2352, 10 Center Drive, MSC 1301, Bethesda, MD 20892 1301, USA
    Rheumatology (Oxford) 49:2381-90. 2010
    ..To assess whether certain environmental factors temporally associated with the onset of juvenile idiopathic inflammatory myopathies (JIIMs) differ between phenotypes...
  16. pmc Damage extent and predictors in adult and juvenile dermatomyositis and polymyositis as determined with the myositis damage index
    Lisa G Rider
    Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, NIH, Bethesda, MD 20892 1301, USA
    Arthritis Rheum 60:3425-35. 2009
    ..We undertook this study to validate the Myositis Damage Index (MDI) in juvenile and adult myositis, to describe the degree and types of damage and to develop predictors of damage...
  17. pmc Deciphering the clinical presentations, pathogenesis, and treatment of the idiopathic inflammatory myopathies
    Lisa G Rider
    Environmental Autoimmunity Group, Program of Clinical Research, National Institute of Environmental Health Sciences, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland 20892, USA
    JAMA 305:183-90. 2011
    ..Knowledge of myositis phenotypes should enhance clinicians' ability to recognize and manage these rare disorders...
  18. ncbi request reprint Mechanisms of disease: Environmental factors in the pathogenesis of rheumatic disease
    Mark Gourley
    Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, NIH, Bethesda, MD 20892 1301, USA
    Nat Clin Pract Rheumatol 3:172-80. 2007
    ....
  19. ncbi request reprint Neopterin and quinolinic acid are surrogate measures of disease activity in the juvenile idiopathic inflammatory myopathies
    Lisa G Rider
    Laboratory of Molecular and Developmental Immunology, Division of Monoclonal Antibodies, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD 20892, USA
    Clin Chem 48:1681-8. 2002
    ..We evaluated the utility of neopterin and quinolinic acid (QUIN) as surrogate measures of disease activity in juvenile idiopathic inflammatory myopathies (IIMs)...
  20. ncbi request reprint Defining Clinical Improvement in Adult and Juvenile Myositis
    Lisa G Rider
    Enviromental Autoimmunity Group, National Institute of Enviromental Health Sciences, National Institutes of Health, Bethesda, MD 20892, USA
    J Rheumatol 30:603-17. 2003
    ..This workshop is the first of several planned to develop multidisciplinary, international consensus on the conduct and reporting of IIM clinical trials...
  21. ncbi request reprint International consensus on preliminary definitions of improvement in adult and juvenile myositis
    Lisa G Rider
    National Institute of Environmental Health Sciences, NIH, Bethesda, Maryland 20892, USA
    Arthritis Rheum 50:2281-90. 2004
    ..To use a core set of outcome measures to develop preliminary definitions of improvement for adult and juvenile myositis as composite end points for therapeutic trials...
  22. ncbi request reprint Possible roles and determinants of microchimerism in autoimmune and other disorders
    Kakali Sarkar
    Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, HHS, 9000 Rockville Pike, NIH 9 1W107, Bethesda, MD 20892 0958, USA
    Autoimmun Rev 3:454-63. 2004
    ....
  23. ncbi request reprint Autoantibodies as predictive and diagnostic markers of idiopathic inflammatory myopathies
    Kakali Sarkar
    NIH 9 1W107, Bethesda, MD 20892, USA
    Autoimmunity 37:291-4. 2004
  24. ncbi request reprint Seasonal influence on the onset of idiopathic inflammatory myopathies in serologically defined groups
    Kakali Sarkar
    National Institute of Environmental Health Sciences, NIH, DHHS, Bethesda, MD 20892, USA
    Arthritis Rheum 52:2433-8. 2005
    ..To assess possible seasonal patterns in the onset of polymyositis (PM) and dermatomyositis (DM)...
  25. ncbi request reprint Measuring therapeutic response in chronic graft-versus-host disease: National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IV. Response Criteria Working Group report
    Steven Z Pavletic
    National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 1203, USA
    Biol Blood Marrow Transplant 12:252-66. 2006
    ..The proposed response criteria are based on current expert consensus opinion and are intended to improve consistency in the conduct and reporting of chronic GVHD trials, but their use remains to be demonstrated in practice...
  26. ncbi request reprint Is occupational exposure to mineral oil a risk factor for rheumatoid arthritis?
    Frederick W Miller
    Environmental Autoimmunity Group, National Institutes of Health, DHHS, Clinical Research Center, Bethesda, MD 20892 1301, USA
    Nat Clin Pract Rheumatol 2:130-1. 2006
  27. pmc Validation of manual muscle testing and a subset of eight muscles for adult and juvenile idiopathic inflammatory myopathies
    Lisa G Rider
    Environmental Autoimmunity Group, Office of Clinical Research, National Institute of Environmental Health Sciences NIH, 10 Center Drive, Bethesda, MD 20892 1301, USA
    Arthritis Care Res (Hoboken) 62:465-72. 2010
    ..To validate manual muscle testing (MMT) for strength assessment in juvenile and adult dermatomyositis (DM) and polymyositis (PM)...
  28. pmc Twins discordant for myositis and systemic lupus erythematosus show markedly enriched autoantibodies in the affected twin supporting environmental influences in pathogenesis
    Lu Gan
    Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, Bethesda, MD, USA
    BMC Musculoskelet Disord 15:67. 2014
    ..Studies of twin pairs discordant for autoimmune conditions provide a unique opportunity to explore contributing factors triggered by complex gene-environment interactions...
  29. pmc Serum proteins and paraproteins in women with silicone implants and connective tissue disease: a case-control study
    Gyorgy Csako
    Department of Laboratory Medicine, Clinical Center, NIH, DHHS, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Arthritis Res Ther 9:R95. 2007
    ..The causes and clinical implications of these findings require further investigation...
  30. pmc HLA type and immune response to Borrelia burgdorferi outer surface protein a in people in whom arthritis developed after Lyme disease vaccination
    Robert Ball
    Center for Biologics Evaluation and Research, FDA, Rockville, Maryland, USA
    Arthritis Rheum 60:1179-86. 2009
    ....
  31. pmc Seasonal birth patterns in myositis subgroups suggest an etiologic role of early environmental exposures
    Leora J Vegosen
    Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, NIH DHHS, 10 Center Drive, Bethesda, MD 20892, USA
    Arthritis Rheum 56:2719-28. 2007
    ..To evaluate whether seasonal early environmental exposures might influence later development of autoimmune disease, by assessing distributions of birth dates in groups of patients with idiopathic inflammatory myopathies (IIMs)...
  32. ncbi request reprint Occupational exposures and autoimmune diseases
    Glinda S Cooper
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Int Immunopharmacol 2:303-13. 2002
    ....
  33. ncbi request reprint Genomic organization, transcriptional mapping, and evolutionary implications of the human bi-directional histidyl-tRNA synthetase locus (HARS/HARSL)
    Terrance P O'Hanlon
    Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, MD 20892, USA
    Biochem Biophys Res Commun 294:609-14. 2002
    ..Human and rodent HARS/HARSL loci are homologous and support a model of inverted gene duplication to explain the emergence of HARSL during mammalian evolution...
  34. pmc Late-onset gastrointestinal pain in juvenile dermatomyositis as a manifestation of ischemic ulceration from chronic endarteropathy
    Gulnara Mamyrova
    Environmental Autoimmunity Group, National Institute of Environmental Health Sciences, Bethesda, Maryland 20892 1301, USA
    Arthritis Rheum 57:881-4. 2007
  35. pmc Metabolic abnormalities and cardiovascular risk factors in children with myositis
    Kathleen Coyle
    National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892 1301, USA
    J Pediatr 155:882-7. 2009
    ..To characterize the metabolic abnormalities and risk factors for future cardiovascular disease in children with myositis...