Nicholas Noinaj

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi TonB-dependent transporters: regulation, structure, and function
    Nicholas Noinaj
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Annu Rev Microbiol 64:43-60. 2010
  2. ncbi Structural insights into the catalytic mechanism of Escherichia coli selenophosphate synthetase
    Nicholas Noinaj
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA
    J Bacteriol 194:499-508. 2012
  3. ncbi Crystal structures of the outer membrane domain of intimin and invasin from enterohemorrhagic E. coli and enteropathogenic Y. pseudotuberculosis
    James W Fairman
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Structure 20:1233-43. 2012
  4. ncbi Structural basis for iron piracy by pathogenic Neisseria
    Nicholas Noinaj
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, Maryland 20892, USA
    Nature 483:53-8. 2012
  5. ncbi Structural engineering of a phage lysin that targets gram-negative pathogens
    Petra Lukacik
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 109:9857-62. 2012
  6. ncbi Structural insights into Ail-mediated adhesion in Yersinia pestis
    Satoshi Yamashita
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 8030, USA
    Structure 19:1672-82. 2011
  7. ncbi Molecular basis for the activation of a catalytic asparagine residue in a self-cleaving bacterial autotransporter
    Travis J Barnard
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, MD 20892, USA
    J Mol Biol 415:128-42. 2012
  8. ncbi Structure of the agonist-bound neurotensin receptor
    Jim F White
    Membrane Protein Structure Function Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20852, USA
    Nature 490:508-13. 2012
  9. ncbi The transferrin-iron import system from pathogenic Neisseria species
    Nicholas Noinaj
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Mol Microbiol 86:246-57. 2012
  10. ncbi The structural biology of β-barrel membrane proteins: a summary of recent reports
    James W Fairman
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Curr Opin Struct Biol 21:523-31. 2011

Collaborators

Detail Information

Publications10

  1. ncbi TonB-dependent transporters: regulation, structure, and function
    Nicholas Noinaj
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Annu Rev Microbiol 64:43-60. 2010
    ..However, the transport mechanism is still unclear. In this review, we summarize recent progress in understanding regulation, structure, and function in TBDTs and questions remaining to be answered...
  2. ncbi Structural insights into the catalytic mechanism of Escherichia coli selenophosphate synthetase
    Nicholas Noinaj
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA
    J Bacteriol 194:499-508. 2012
    ....
  3. ncbi Crystal structures of the outer membrane domain of intimin and invasin from enterohemorrhagic E. coli and enteropathogenic Y. pseudotuberculosis
    James W Fairman
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Structure 20:1233-43. 2012
    ..We then use this set of sequences along with our structural data to find and map the evolutionarily constrained residues within the β domain...
  4. ncbi Structural basis for iron piracy by pathogenic Neisseria
    Nicholas Noinaj
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, Maryland 20892, USA
    Nature 483:53-8. 2012
    ..Our studies provide a rational basis for the specificity of TbpA for human transferrin, show how TbpA promotes iron release from transferrin, and elucidate how TbpB facilitates this process...
  5. ncbi Structural engineering of a phage lysin that targets gram-negative pathogens
    Petra Lukacik
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 109:9857-62. 2012
    ....
  6. ncbi Structural insights into Ail-mediated adhesion in Yersinia pestis
    Satoshi Yamashita
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 8030, USA
    Structure 19:1672-82. 2011
    ..We also evaluated the contribution of laminin to delivery of Yops to HEp-2 cells. This work constitutes a structural description of how a bacterial outer membrane protein uses a multivalent approach to bind host cells...
  7. ncbi Molecular basis for the activation of a catalytic asparagine residue in a self-cleaving bacterial autotransporter
    Travis J Barnard
    Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, US National Institutes of Health, Bethesda, MD 20892, USA
    J Mol Biol 415:128-42. 2012
    ..Together, these findings provide insight into factors important for asparagine cyclization, a mechanism broadly used for protein cleavage...
  8. ncbi Structure of the agonist-bound neurotensin receptor
    Jim F White
    Membrane Protein Structure Function Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20852, USA
    Nature 490:508-13. 2012
    ....
  9. ncbi The transferrin-iron import system from pathogenic Neisseria species
    Nicholas Noinaj
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Mol Microbiol 86:246-57. 2012
    ....
  10. ncbi The structural biology of β-barrel membrane proteins: a summary of recent reports
    James W Fairman
    National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Curr Opin Struct Biol 21:523-31. 2011
    ..However, they demonstrate many of the advancements made within the field of transmembrane protein structure in the past few years...