D A Nielsen
Affiliation: National Institutes of Health
- Sequence, splice site and population frequency distribution analyses of the polymorphic human tryptophan hydroxylase intron 7D A Nielsen
Section of Molecular Genetics, DICBR, NIAAA, National Institutes of Health, Rockville, MD 20852, USA
Brain Res Mol Brain Res 45:145-8. 1997..TPH mRNA was reverse-transcribed and sequenced. No aberrant splice products from the 779A or 779G TPH genes were detected nor were any other polymorphic nucleotides found...
- A tryptophan hydroxylase gene marker for suicidality and alcoholismD A Nielsen
Section of Molecular Genetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA
Arch Gen Psychiatry 55:593-602. 1998..We previously reported that, in Finns, TPH genotype was associated with suicidality, a pathophysiological mechanism that may involve impaired impulse control...
- Two naturally occurring amino acid substitutions in the human 5-HT1A receptor: glycine 22 to serine 22 and isoleucine 28 to valine 28B Nakhai
Section of Molecular Genetics, NIAAA, National Institutes of Health, Rockville, MD 20852, USA
Biochem Biophys Res Commun 210:530-6. 1995..This is the first report of a polymorphism in the human 5-HT1A receptor gene that alters the structure of the 5-HT1A receptor protein composition...
- Isolation and characterization of murine vav2, a member of the vav family of proto-oncogenesK E Schuebel
Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, Maryland 20852, USA
Oncogene 13:363-71. 1996..Our results suggest that Vav family members mediate functions important in the regulation of cell architecture and proliferation in most, if not all, tissues...