Timothy K Newman

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint The relationship between childhood abuse and dissociation. Is it influenced by catechol-O-methyltransferase (COMT) activity?
    Jonathan B Savitz
    MRC UCT Human Genetics Research Unit, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, South Africa
    Int J Neuropsychopharmacol 11:149-61. 2008
  2. ncbi request reprint Effectiveness of human microsatellite loci for assessing paternity in a captive colony of vervets (Chlorocebus aethiops sabaeus)
    Timothy K Newman
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas, USA
    Am J Primatol 56:237-43. 2002
  3. ncbi request reprint Monoamine oxidase A gene promoter variation and rearing experience influences aggressive behavior in rhesus monkeys
    Timothy K Newman
    Laboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, MD 20852, USA
    Biol Psychiatry 57:167-72. 2005
  4. ncbi request reprint Mitochondrial phylogeny and systematics of baboons (Papio)
    Timothy K Newman
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78227, USA
    Am J Phys Anthropol 124:17-27. 2004
  5. ncbi request reprint Interaction between serotonin transporter gene variation and rearing condition in alcohol preference and consumption in female primates
    Christina S Barr
    National Institute on Alcoholism and Alcohol Abuse, Laboratory of Clinical Studies and National Institute of Child Health and Human Development, Laboratory of Comparative Ethology, National Institutes of Health, Poolesville, MD, USA
    Arch Gen Psychiatry 61:1146-52. 2004
  6. pmc Sexual dichotomy of an interaction between early adversity and the serotonin transporter gene promoter variant in rhesus macaques
    Christina S Barr
    Primate Unit, Laboratory of Clinical Studies, Division of Intramural Clinical and Biological Research, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Poolesville, MD 20837, USA
    Proc Natl Acad Sci U S A 101:12358-63. 2004
  7. ncbi request reprint Rearing condition and rh5-HTTLPR interact to influence limbic-hypothalamic-pituitary-adrenal axis response to stress in infant macaques
    Christina S Barr
    Laboratory of Clinical Studies, National Institute of Alcoholism and Alcohol Abuse, National Institutes of Health, Poolesville, Maryland 20837, USA
    Biol Psychiatry 55:733-8. 2004
  8. ncbi request reprint Association between the recombinant human serotonin transporter linked promoter region polymorphism and behavior in rhesus macaques during a separation paradigm
    Simona Spinelli
    National Institute on Alcohol Abuse and Alcoholism, NIH Animal Center, P O Box 529, Poolesville, MD 20837, USA
    Dev Psychopathol 19:977-87. 2007
  9. ncbi request reprint Serotonin transporter gene variation is associated with alcohol sensitivity in rhesus macaques exposed to early-life stress
    Christina S Barr
    Labortatory of Clinical Studies, Primate Unit, National Institute on Alcohol Abuse and Alcoholism, NIH Animal Center, PO Box 529, Building 112, Poolesville, MD 20837, USA
    Alcohol Clin Exp Res 27:812-7. 2003
  10. pmc Genetic modulation of cognitive flexibility and socioemotional behavior in rhesus monkeys
    Alicia Izquierdo
    Laboratory of Neuropsychology, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 104:14128-33. 2007

Detail Information

Publications19

  1. ncbi request reprint The relationship between childhood abuse and dissociation. Is it influenced by catechol-O-methyltransferase (COMT) activity?
    Jonathan B Savitz
    MRC UCT Human Genetics Research Unit, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, South Africa
    Int J Neuropsychopharmacol 11:149-61. 2008
    ..The current findings support the involvement of the COMT Val158Met polymorphism in mediating the relationship between trauma and psychopathology...
  2. ncbi request reprint Effectiveness of human microsatellite loci for assessing paternity in a captive colony of vervets (Chlorocebus aethiops sabaeus)
    Timothy K Newman
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas, USA
    Am J Primatol 56:237-43. 2002
    ..Our results provide a panel of markers derived from the human genome that is suitable for assessing genetic variation and paternity in vervets...
  3. ncbi request reprint Monoamine oxidase A gene promoter variation and rearing experience influences aggressive behavior in rhesus monkeys
    Timothy K Newman
    Laboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, MD 20852, USA
    Biol Psychiatry 57:167-72. 2005
    ..We tested the hypothesis that a repeat polymorphism in the rhesus macaque MAOA gene promoter region influences aggressive behavior in male subjects...
  4. ncbi request reprint Mitochondrial phylogeny and systematics of baboons (Papio)
    Timothy K Newman
    Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, Texas 78227, USA
    Am J Phys Anthropol 124:17-27. 2004
    ..The overall phylogeny, when combined with paleontological data, suggests a southern African origin for extant Papio baboons, with all extant lineages sharing a common mitochondrial ancestor at approximately 1.8 Ma...
  5. ncbi request reprint Interaction between serotonin transporter gene variation and rearing condition in alcohol preference and consumption in female primates
    Christina S Barr
    National Institute on Alcoholism and Alcohol Abuse, Laboratory of Clinical Studies and National Institute of Child Health and Human Development, Laboratory of Comparative Ethology, National Institutes of Health, Poolesville, MD, USA
    Arch Gen Psychiatry 61:1146-52. 2004
    ....
  6. pmc Sexual dichotomy of an interaction between early adversity and the serotonin transporter gene promoter variant in rhesus macaques
    Christina S Barr
    Primate Unit, Laboratory of Clinical Studies, Division of Intramural Clinical and Biological Research, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Poolesville, MD 20837, USA
    Proc Natl Acad Sci U S A 101:12358-63. 2004
    ..This interactive effect may underlie the increased incidence of certain stress-related disorders in women...
  7. ncbi request reprint Rearing condition and rh5-HTTLPR interact to influence limbic-hypothalamic-pituitary-adrenal axis response to stress in infant macaques
    Christina S Barr
    Laboratory of Clinical Studies, National Institute of Alcoholism and Alcohol Abuse, National Institutes of Health, Poolesville, Maryland 20837, USA
    Biol Psychiatry 55:733-8. 2004
    ..We wanted to determine whether serotonin transporter gene promoter variation (rh-5HTTLPR) and rearing condition would interact to influence endocrine responses to stress in infant rhesus macaques...
  8. ncbi request reprint Association between the recombinant human serotonin transporter linked promoter region polymorphism and behavior in rhesus macaques during a separation paradigm
    Simona Spinelli
    National Institute on Alcohol Abuse and Alcoholism, NIH Animal Center, P O Box 529, Poolesville, MD 20837, USA
    Dev Psychopathol 19:977-87. 2007
    ....
  9. ncbi request reprint Serotonin transporter gene variation is associated with alcohol sensitivity in rhesus macaques exposed to early-life stress
    Christina S Barr
    Labortatory of Clinical Studies, Primate Unit, National Institute on Alcohol Abuse and Alcoholism, NIH Animal Center, PO Box 529, Building 112, Poolesville, MD 20837, USA
    Alcohol Clin Exp Res 27:812-7. 2003
    ..In addition, we have demonstrated that macaques separated from their mothers and reared in peer-only groups are more likely to consume alcohol as adults...
  10. pmc Genetic modulation of cognitive flexibility and socioemotional behavior in rhesus monkeys
    Alicia Izquierdo
    Laboratory of Neuropsychology, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 104:14128-33. 2007
    ..Because behaviors modulated by the 5-HTTLPR are a subset of those dependent on the VMPFC, analysis of structural and functional correlates of gene variation in this region may inform the nature of the genetic modulation of cognition...
  11. pmc A non-additive interaction of a functional MAO-A VNTR and testosterone predicts antisocial behavior
    Rickard L Sjoberg
    Uppsala University Centre for Clinical Research, Central Hospital, Vasteras, Sweden
    Neuropsychopharmacology 33:425-30. 2008
    ....
  12. doi request reprint Catechol-o-methyltransferase genotype and childhood trauma may interact to impact schizotypal personality traits
    Jonathan Savitz
    MRC UCT Human Genetics Research Unit, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa
    Behav Genet 40:415-23. 2010
    ..We raise the possibility that genetically-driven variation in COMT may interact with childhood trauma to contribute to the risk of developing schizotypal personality traits...
  13. ncbi request reprint The use of adolescent nonhuman primates to model human alcohol intake: neurobiological, genetic, and psychological variables
    Christina S Barr
    V Research Fellow, NIH Animal Center, Building 112, P O Box 529, Poolesville, MD 20837 0529, USA
    Ann N Y Acad Sci 1021:221-33. 2004
    ....
  14. ncbi request reprint Early maternal rejection affects the development of monoaminergic systems and adult abusive parenting in rhesus macaques (Macaca mulatta)
    Dario Maestripieri
    Department of Comparative Human Development, The University of Chicago, Chicago, IL 60637, USA
    Behav Neurosci 120:1017-24. 2006
    ....
  15. ncbi request reprint Differential functional variability of serotonin transporter and monoamine oxidase a genes in macaque species displaying contrasting levels of aggression-related behavior
    Jens R Wendland
    Clinical and Molecular Psychobiology, Department of Psychiatry and Psychotherapy, University of Wurzburg, 97080, Wurzburg, Germany
    Behav Genet 36:163-72. 2006
    ..Taken together, these findings suggest that genetic variation of serotonergic neurotransmission may play an important role in determining inter-species differences in aggression related behavior in macaques...
  16. ncbi request reprint Mitochondrial evidence for the origin of hamadryas baboons
    Derek E Wildman
    Department of Anthropology, New York Univesity, USA
    Mol Phylogenet Evol 32:287-96. 2004
    ..The mitochondrial paraphyly of Ethiopian hamadryas and anubis (P. anubis) baboons suggests an extensive and complex history of sex-specific introgression...
  17. pmc Moderate level fetal alcohol exposure and serotonin transporter gene promoter polymorphism affect neonatal temperament and limbic-hypothalamic-pituitary-adrenal axis regulation in monkeys
    Gary W Kraemer
    Department of Kinesiology, University of Wisconsin Madison, Madison, Wisconsin, USA
    Biol Psychiatry 63:317-24. 2008
    ..This study determined whether moderate FA-exposure interacts with polymorphism in the 5-HT transporter gene to increase the incidence or severity of fetal alcohol effects in rhesus monkeys...
  18. ncbi request reprint Genetic contributions to social impulsivity and aggressiveness in vervet monkeys
    Lynn A Fairbanks
    Neuropsychiatric Institute, University of California Los Angeles, California 90024, USA
    Biol Psychiatry 55:642-7. 2004
    ..This study assessed the genetic contribution to impulsivity and aggressiveness in a social context using a nonhuman primate model...
  19. ncbi request reprint Warriors versus worriers: the role of COMT gene variants
    Dan J Stein
    Department of Mental Health and Psychiatry, University of Cape Town, South Africa
    CNS Spectr 11:745-8. 2006
    ..Some evidence suggests that Val158 alleles are associated with schizophrenia, while Met158 alleles are associated with anxiety...