Research Topics
| A F NeuwaldSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Detecting patterns in protein sequencesA F Neuwald
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894
J Mol Biol 239:698-712. 1994..In a search of a large set of sequences for internal repeats, the method detected novel ankyrin-like repeats in an Escherichia coli protein...
Extracting protein alignment models from the sequence databaseA F Neuwald
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
Nucleic Acids Res 25:1665-77. 1997..Moreover, this method automatically generates models of these ancient conserved regions for rapid and sensitive screening of sequences...
An unexpected structural relationship between integral membrane phosphatases and soluble haloperoxidasesA F Neuwald
National Center for Biotechnology Information, National Institutes of Health, Bethesda, Maryland 20894, USA
Protein Sci 6:1764-7. 1997..This implies that a similar arrangement of catalytic residues specifies the active site within both soluble and membrane spanning domains...
A shared domain between a spindle assembly checkpoint protein and Ypt/Rab-specific GTPase-activatorsA F Neuwald
National Center for Biotechnology Information National Institutes of Health, Bethesda, MD 20894, USA
Trends Biochem Sci 22:243-4. 1997
A theory of information with special application to search problemsW J Wilbur
National Library of Medicine, Bethesda, MD 20894, USA
Comput Chem 24:33-42. 2000..The last part of the paper presents several examples where confirmatory information is used to quantify protein structural properties in a search setting...
