John K Neubert

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Microdialysis in trigeminal ganglia
    John K Neubert
    Pain Neurosensory Mechanisms Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA
    Brain Res Brain Res Protoc 10:102-8. 2002
  2. ncbi request reprint Peripherally induced resiniferatoxin analgesia
    John K Neubert
    Pain and Neurosensory Mechanisms Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA
    Pain 104:219-28. 2003
  3. pmc Deletion of vanilloid receptor 1-expressing primary afferent neurons for pain control
    Laszlo Karai
    National Institute of Dental and Craniofacial Research, Bethesda, Maryland 20892, USA
    J Clin Invest 113:1344-52. 2004
  4. ncbi request reprint Comparison of experimental and acute clinical pain responses in humans as pain phenotypes
    Hyungsuk Kim
    Pain and Neurosensory Mechanisms Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Pain 5:377-84. 2004
  5. ncbi request reprint Genetic influence on variability in human acute experimental pain sensitivity associated with gender, ethnicity and psychological temperament
    Hyungsuk Kim
    Pain and Neurosensory Mechanisms Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, 10 center Dr Building 10 Rm 1N103, Bethesda, MD 20892 1197, USA
    Pain 109:488-96. 2004
  6. pmc Sensitization of spinal cord nociceptive neurons with a conjugate of substance P and cholera toxin
    Robert M Caudle
    Department of Oral and Maxillofacial Surgery and Diagnostic Sciences, University of Florida College of Dentistry, Gainesville, FL 32610, USA
    BMC Neurosci 8:30. 2007
  7. pmc Sex differences in thermal pain sensitivity and sympathetic reactivity for two strains of rat
    Charles J Vierck
    Department of Neuroscience, University of Florida, Gainesville, Florida 332601 0244, USA
    J Pain 9:739-49. 2008
  8. pmc Perineural resiniferatoxin selectively inhibits inflammatory hyperalgesia
    John K Neubert
    College of Dentistry Department of Orthodontics, University of Florida, Gainesville, FL, USA
    Mol Pain 4:3. 2008
  9. pmc Characterization of cold sensitivity and thermal preference using an operant orofacial assay
    Heather L Rossi
    College of Dentistry Department of Orthodontics, University of Florida, Gainesville, FL 32610 0444, USA
    Mol Pain 2:37. 2006
  10. ncbi request reprint Differentiation between capsaicin-induced allodynia and hyperalgesia using a thermal operant assay
    John K Neubert
    College of Dentistry, Department of Orthodontics, University of Florida, Gainesville, FL, USA
    Behav Brain Res 170:308-15. 2006

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Microdialysis in trigeminal ganglia
    John K Neubert
    Pain Neurosensory Mechanisms Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA
    Brain Res Brain Res Protoc 10:102-8. 2002
    ..Microdialysis performed in the TG thus provides a valuable site for recovery and measurement of a variety of extracellular substances that may be integral in the processing of trigeminal sensory information...
  2. ncbi request reprint Peripherally induced resiniferatoxin analgesia
    John K Neubert
    Pain and Neurosensory Mechanisms Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA
    Pain 104:219-28. 2003
    ..The results demonstrate the efficacy and therapeutic potential of reversible, peripheral C-fiber 'inactivation' for intermediate duration pain control...
  3. pmc Deletion of vanilloid receptor 1-expressing primary afferent neurons for pain control
    Laszlo Karai
    National Institute of Dental and Craniofacial Research, Bethesda, Maryland 20892, USA
    J Clin Invest 113:1344-52. 2004
    ..The results suggest that nociceptive neuronal or nerve terminal deletion will be effective and broadly applicable as strategies for pain management...
  4. ncbi request reprint Comparison of experimental and acute clinical pain responses in humans as pain phenotypes
    Hyungsuk Kim
    Pain and Neurosensory Mechanisms Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Pain 5:377-84. 2004
    ..The predictive value of experimental pain for clinically induced pain is weak and not reliable...
  5. ncbi request reprint Genetic influence on variability in human acute experimental pain sensitivity associated with gender, ethnicity and psychological temperament
    Hyungsuk Kim
    Pain and Neurosensory Mechanisms Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, 10 center Dr Building 10 Rm 1N103, Bethesda, MD 20892 1197, USA
    Pain 109:488-96. 2004
    ..Our observations demonstrate that gender, ethnicity and temperament contribute to individual variation in thermal and cold pain sensitivity by interactions with TRPV1 and OPRD1 single nucleotide polymorphisms...
  6. pmc Sensitization of spinal cord nociceptive neurons with a conjugate of substance P and cholera toxin
    Robert M Caudle
    Department of Oral and Maxillofacial Surgery and Diagnostic Sciences, University of Florida College of Dentistry, Gainesville, FL 32610, USA
    BMC Neurosci 8:30. 2007
    ..This conjugate should be taken up selectively by neurokinin receptor expressing neurons resulting in enhanced adenylate cyclase activity and neuronal firing...
  7. pmc Sex differences in thermal pain sensitivity and sympathetic reactivity for two strains of rat
    Charles J Vierck
    Department of Neuroscience, University of Florida, Gainesville, Florida 332601 0244, USA
    J Pain 9:739-49. 2008
    ..Therefore, understanding relationships between gender differences in pain sensitivity and sympathetic activation could shed light on mechanisms for some varieties of chronic pain...
  8. pmc Perineural resiniferatoxin selectively inhibits inflammatory hyperalgesia
    John K Neubert
    College of Dentistry Department of Orthodontics, University of Florida, Gainesville, FL, USA
    Mol Pain 4:3. 2008
    ..We propose that this method could represent a beneficial treatment for a range of chronic pain problems, including neuropathic and inflammatory pain not responding to other therapies...
  9. pmc Characterization of cold sensitivity and thermal preference using an operant orofacial assay
    Heather L Rossi
    College of Dentistry Department of Orthodontics, University of Florida, Gainesville, FL 32610 0444, USA
    Mol Pain 2:37. 2006
    ..Male and female rats were trained to drink sweetened milk while pressing their shaved faces against a thermode. This presents a conflict paradigm between milk reward and thermal stimulation...
  10. ncbi request reprint Differentiation between capsaicin-induced allodynia and hyperalgesia using a thermal operant assay
    John K Neubert
    College of Dentistry, Department of Orthodontics, University of Florida, Gainesville, FL, USA
    Behav Brain Res 170:308-15. 2006
    ..This technique provides an alternative to reflex tests of orofacial sensitivity, and it presents a pivotal link for translating basic pain research into clinic trial strategies...
  11. ncbi request reprint Peripheral targeting of the trigeminal ganglion via the infraorbital foramen as a therapeutic strategy
    John K Neubert
    Department of Orthodontics, College of Dentistry, University of Florida, 1600 S W Archer Road, P O Box 100444, Gainesville, FL 32610 0444, USA
    Brain Res Brain Res Protoc 15:119-26. 2005
    ..This technique minimizes trauma to brain structures that may have an impact on pain perception...
  12. ncbi request reprint Use of a novel thermal operant behavioral assay for characterization of orofacial pain sensitivity
    John K Neubert
    Department of Orthodontics, College of Dentistry, University of Florida, 1600 SW Archer Road, P O Box 100444, Gainesville, FL 32610 0444, USA
    Pain 116:386-95. 2005
    ..These data reflect an orofacial pain behavior profile that was based on an animal's responses in an operant escape paradigm. This technique allows evaluation of nociceptive processing and modulation throughout the neuraxis...
  13. doi request reprint Toothache or trigeminal neuralgia: treatment dilemmas
    Christopher J Spencer
    J Pain 9:767-70. 2008