Research Topics
Genomes and GenesSpecies | R G NelsonSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Podocyte detachment and reduced glomerular capillary endothelial fenestration promote kidney disease in type 2 diabetic nephropathyE Jennifer Weil
National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85014 4972, USA
Kidney Int 82:1010-7. 2012..Whether podocyte detachment creates conduits for proteins to escape the glomerular circulation and reduced endothelial fenestration lowers glomerular hydraulic permeability requires further study...
Effect of intrauterine diabetes exposure on the incidence of end-stage renal disease in young adults with type 2 diabetesMeda E Pavkov
Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Diabetes Care 33:2396-8. 2010..We examined the effect of intrauterine diabetes exposure (IDE) on the incidence of diabetic end-stage renal disease (ESRD) in Pima Indians with type 2 diabetes...
Course of renal disease in Pima Indians with non-insulin-dependent diabetes mellitusR G Nelson
Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, USA
Kidney Int Suppl 63:S45-8. 1997....
Plasma lipoproteins and incidence of non-insulin-dependent diabetes mellitus in Pima Indians: protective effect of HDL cholesterol in womenA Fagot-Campagna
National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, AZ 85014, USA
Atherosclerosis 128:113-9. 1997..8 mmol/1) or impaired (7.8 mmol/l < or = 2-h glucose < 11.1 mmol/l) glucose tolerance at baseline. These results indicate that lipoprotein disorders are an early accompaniment of the abnormalities that lead to NIDDM...
Intrauterine diabetes exposure and the risk of renal disease in diabetic Pima IndiansR G Nelson
Phoenix Epidemiology and Clinical Research Branch, National Insitute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85014 4972, USA
Diabetes 47:1489-93. 1998..The effect of this exposure appears to be independent of other susceptibility factors that lead to nephropathy in diabetes...
Survival during renal replacement therapy for diabetic end-stage renal disease in Pima IndiansR G Nelson
Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, AZ 85014, USA
Diabetes Care 19:1333-7. 1996..To examine survival in Pima Indians receiving renal replacement therapy for end-stage renal disease attributed to NIDDM...
An epidemic of proteinuria in Pima Indians with type 2 diabetes mellitusR G Nelson
Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Arizona, USA
Kidney Int 54:2081-8. 1998..Little is known about secular changes in the risk of proteinuria in Type 2 diabetes...
Increasing incidence of proteinuria and declining incidence of end-stage renal disease in diabetic Pima IndiansM E Pavkov
Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, USA
Kidney Int 70:1840-6. 2006..On the other hand, the incidence of ESRD declined after 1990, coinciding with improved control of blood pressure, hyperglycemia, and perhaps other risk factors...
Serum cholesterol and mortality rates in a Native American population with low cholesterol concentrations: a U-shaped associationA Fagot-Campagna
National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Ariz 85014, USA
Circulation 96:1408-15. 1997..The present report evaluates whether low cholesterol is likely to be a causal factor for mortality from all causes or from specific causes...
The effect of Indian or Anglo dietary preference on the incidence of diabetes in Pima IndiansD E Williams
Phoenix Epidemiology and Clinical Research Branch, National Institutes of Diabetes and Digestive and Kidney Diseases, Arizona 85014, USA
Diabetes Care 24:811-6. 2001..We examined the long-term effects of a self-assessed traditional or nontraditional dietary pattern on the development of type 2 diabetes in 165 nondiabetic Pima Indians...
Genetics of diabetic nephropathy in the Pima IndiansG Imperatore
Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway, MS K10, Atlanta, GA 30341, USA
Curr Diab Rep 1:275-81. 2001..Analyses conducted by both parametric (model-based) and nonparametric methods revealed tentative evidence for nephropathy susceptibility loci on chromosomes 3q, 7q, 18q, and 20p...
The impact of disadvantage on the development and progression of diabetic kidney diseaseE J Weil
Diabetes Epidemiology and Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ, USA
Clin Nephrol 74:S32-8. 2010..They are also at increased risk of kidney disease attributable to diabetes, and for many, the cost of managing their kidney disease far exceeds their available resources...
Periodontal disease and diabetesR G Nelson
Diabetes Epidemiology and Clinical Research Section, Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ 85014-4972, USA
Oral Dis 14:204-5. 2008
HLA-DRB1 reduces the risk of type 2 diabetes mellitus by increased insulin secretionR C Williams
Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 1550 East Indian School Road, Phoenix, AZ 85014, USA
Diabetologia 54:1684-92. 2011..We sought to identify the physiological implications of genetic variation at the HLA-DRB1 region in full-heritage Pima Indians in Arizona...
Variants in the gene encoding aldose reductase (AKR1B1) and diabetic nephropathy in American IndiansJ K Wolford
Translational Genomics Research Institute, Diabetes Research Unit, Phoenix, AZ 85004, USA
Diabet Med 23:367-76. 2006..As AKR1B1 is located on 7q35, where we have previously reported linkage to diabetic nephropathy in Pima Indians, this study examined the association of AKR1B1 variants with diabetic nephropathy in this population...
Predictive value of albuminuria in American Indian youth with or without type 2 diabetesNan Hee Kim
Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona, USA
Pediatrics 125:e844-51. 2010..To examine the prognostic significance of elevated albuminuria in youth with type 2 diabetes...
Alpha-oxoaldehyde metabolism and diabetic complicationsP J Beisswenger
Department of Medicine, Diabetes, Endocrinology and Metabolism, Dartmouth Medical School and Dartmouth Hitchcock Medical Center, 1 Medical Center Drive, Lebanon, NH 03756, U S A
Biochem Soc Trans 31:1358-63. 2003..New therapeutic interventions designed to control these endogenous mechanisms could potentially enhance protection against excessive glycation and prevent or reverse complications of long-term diabetes...
Heritability of the severity of diabetic retinopathy: the FIND-Eye studyNedal H Arar
Family Investigation of Nephropathy and Diabetes FIND Genetic Analysis and Data Coordinating Center, Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, USA
Invest Ophthalmol Vis Sci 49:3839-45. 2008....
