Research Topics
Species | K B NelsonSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Can we prevent cerebral palsy?Karin B Nelson
Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA
N Engl J Med 349:1765-9. 2003- The neurologically impaired child and alleged malpractice at birthK B Nelson
Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA
Neurol Clin 17:283-93. 1999..There is no evidence that caesarean section can prevent cerebral palsy in term infants... - Selected neurotrophins, neuropeptides, and cytokines: developmental trajectory and concentrations in neonatal blood of children with autism or Down syndromePhillip G Nelson
National Institute of Child Health and Development, Building 31, Room 2A25, Bethesda, MD 20892 2426, USA
Int J Dev Neurosci 24:73-80. 2006..We discuss interrelationships of VIP, NT-3 and IL-8 and their potential relevance to features of the neuropathology of autism or Down syndrome... - Thimerosal and autism?Karin B Nelson
Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892 1447, USA
Pediatrics 111:674-9. 2003 - Stroke in newborn infantsKarin B Nelson
Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1447, USA
Lancet Neurol 3:150-8. 2004..There is much to be learned about the natural history of perinatal stroke, and there are as yet no evidence-based strategies for prevention or treatment... - Genetic polymorphisms and cerebral palsy in very preterm infantsKarin B Nelson
National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892 1447, and Children s Hospital and Research Center at Oakland, CA 94609 1673, USA
Pediatr Res 57:494-9. 2005..We conclude that further study of genetic factors that may influence susceptibility to CP in very preterm infants is warranted... - Thrombophilias, perinatal stroke, and cerebral palsyKarin B Nelson
National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892 1447, USA
Clin Obstet Gynecol 49:875-84. 2006..This review discusses the clinical entity, perinatal stroke, and its relationship to thrombophilias, inherited and acquired, and to maternal and pregnancy factors... - Perinatal ischemic strokeKarin B Nelson
National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892 1447, USA
Stroke 38:742-5. 2007..Maternal and infant thrombophilias, genetic and acquired, play a role. Rarely is >1 child in a sibship affected, and environmental factors-substantially less studied, to date--are likely to be key determinants of risk... - Is it HIE? And why that mattersKarin B Nelson
National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892, USA
Acta Paediatr 96:1113-4. 2007 
Is cerebral palsy preventable?Karin B Nelson
National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892 2540, USA
Curr Opin Neurol 21:129-35. 2008..To use evidence of good medical quality to update information on strategies for prevention of cerebral palsy, and on the success of these preventive efforts to date...- Causative factors in cerebral palsyKarin B Nelson
National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, MD 20892 2540, USA
Clin Obstet Gynecol 51:749-62. 2008..The contribution of genetic vulnerabilities that interact with environmental stressors is an emerging aspect of our understanding of causative factors in CP... - Neonatal cytokines and cerebral palsy in very preterm infantsKarin B Nelson
Neuroepidemiology Branch, National Institutes of Neurological Disorder and Stroke, Bethesda, MD 20892, USA
Pediatr Res 53:600-7. 2003..Inflammatory cytokines in neonatal blood of very premature infants did not distinguish those with later diagnoses of CP from control children... - The epidemiology of cerebral palsy in term infantsKarin B Nelson
Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892 1447, USA
Ment Retard Dev Disabil Res Rev 8:146-50. 2002..There have not yet been studies examining whether medical interventions directed at infection or coagulation disorder can reduce the frequency of CP... - Causes of cerebral palsyK B Nelson
California Birth Defects Monitoring Program, California Department of Health Services, Emeryville, USA
Curr Opin Pediatr 11:487-91. 1999..Recognition of a broader set of causal possibilities encourages hope for new strategies for the prevention of cerebral palsy... - Neuropeptides and neurotrophins in neonatal blood of children with autism or mental retardationK B Nelson
National Institute of Neurological Diseases and Stroke, Bethesda, MD 20892 1447, USA
Ann Neurol 49:597-606. 2001..In autism and in a heterogeneous group of disorders of cognitive function, overexpression of certain neuropeptides and neurotrophins was observed in peripheral blood drawn in the first days of life... - Selection of neonates for neuroprotective therapies: one set of criteria applied to a populationK B Nelson
Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA
Arch Pediatr Adolesc Med 153:393-8. 1999..To estimate the proportion of children with cerebral palsy (CP) who had signs of birth asphyxia" in the early hours of life, and to examine the nature of the illnesses in those infants... - Overview: infection during pregnancy and neurologic outcome in the childKarin B Nelson
Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892-1447, USA
Ment Retard Dev Disabil Res Rev 8:1-2. 2002 - Infection, inflammation and the risk of cerebral palsyK B Nelson
Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
Curr Opin Neurol 13:133-9. 2000..The mechanisms involved are not well understood and may differ in very immature versus term infants. Term infants exposed to maternal infection are predisposed to delivery room depression and neonatal encephalopathy... - Congenital abnormalities among children with cerebral palsy: More evidence for prenatal antecedentsL A Croen
March of Dimes Birth Defects Foundation, California Department of Health Services, California Birth Defects Monitoring Program, Oakland, CA, USA
J Pediatr 138:804-10. 2001..CONCLUSION: These findings provide further evidence that factors operating in the prenatal period contribute significantly to the etiology of CP... - Intrauterine exposure to infection and risk of cerebral palsy in very preterm infantsJudith K Grether
California Birth Defects Monitoring Program, California Department of Health Services, Oakland, CA, USA
Arch Pediatr Adolesc Med 157:26-32. 2003..To evaluate exposure to intrauterine infection as an independent risk factor for spastic cerebral palsy (CP) among very prematurely born infants... - Epidemiology of perinatal strokeJ K Lynch
Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA
Curr Opin Pediatr 13:499-505. 2001.... - Cerebrovascular disorders in children with the factor V Leiden mutationJ K Lynch
Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA
J Child Neurol 16:735-44. 2001..This mutation should be considered in the evaluation of children with a stroke or its sequelae, including infants with perinatal stroke... - The placenta and neurologic and psychiatric outcomes in the child: study design mattersK B Nelson
Department of Neurology, Children s National Medical Center, Washington, DC, USA
Placenta 32:623-5. 2011..A new generation of studies, difficult but potentially enormously rewarding, will be needed for clinical investigations of the placenta and fetal brain development... 
Headache and biomarkers predictive of vascular disease in a representative sample of US childrenKarin B Nelson
National Institute of Neurological Disorders and Stroke, Bldg 31, Room 8A03, Bethesda, MD 20892 2450, USA
Arch Pediatr Adolesc Med 164:358-62. 2010..To examine the association of childhood headache disorders with markers of risk for cardiovascular and cerebrovascular disease...- Ischemic perinatal stroke: summary of a workshop sponsored by the National Institute of Child Health and Human Development and the National Institute of Neurological Disorders and StrokeTonse N K Raju
National Institute of Child Health and Human Development, Bethesda, MD 20892, USA
Pediatrics 120:609-16. 2007..This article provides a summary of the workshop... - The risk of mortality or cerebral palsy in twins: a collaborative population-based studyAnn I Scher
Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
Pediatr Res 52:671-81. 2002..Co-twin death was a strong predictor of CP in surviving twins. This risk was the same for same- and different-sex pairs, and observed both for preterm and term infants... - Report of the National Institute of Neurological Disorders and Stroke workshop on perinatal and childhood strokeJohn Kylan Lynch
Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA
Pediatrics 109:116-23. 2002..The impact of maternal and perinatal factors on risk and outcome of neonatal stroke needs to be studied. This information is essential to identifying significant areas for future treatment and prevention... - Prothrombotic factors in children with stroke or porencephalyJohn Kylan Lynch
National Institute of Neurological Disorders and Stroke, Building 10, Room 5S220, 10 Center Dr, MSC 1447, Bethesda, MD 20892 1447, USA
Pediatrics 116:447-53. 2005..This study compared the frequencies of genetic and functional coagulation abnormalities in children with arterial ischemic stroke or porencephaly with frequencies in previously published studies... - How common are gastrointestinal disorders in children with autism?Thea Kuddo
Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892, USA
Curr Opin Pediatr 15:339-43. 2003.... - Neonatal encephalopathy: etiology and outcomeKarin B Nelson
Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, USA
Dev Med Child Neurol 47:292. 2005 - Genetic polymorphisms and spontaneous preterm birthCatherine S Gibson
School of Paediatrics and Reproductive Health, University of Adelaide, Adelaide, Australia
Obstet Gynecol 109:384-91. 2007..To examine whether selected genetic polymorphisms in the infant are associated with spontaneous preterm birth (less than 37 weeks) among children with or without later-diagnosed cerebral palsy... - 'Defining hypoxic-ischemic birth events'Karin B Nelson
Dev Med Child Neurol 45:71; author reply 71-2. 2003 - Chorioamnionitis and brain injuryRodney E Willoughby
Eudowood Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins University, 600 N Wolfe St, Park 256, Baltimore, MD 21287 4933, USA
Clin Perinatol 29:603-21. 2002.... - Perinatal arterial stroke: understanding mechanisms and outcomesYvonne W Wu
Department of Neurology, University of California San Francisco, San Francisco, California 94117, USA
Semin Neurol 25:424-34. 2005..The incidence, clinical presentation, pathogenesis, risk factors, and outcome of this increasingly recognized disorder are reviewed... - In utero exposure to antiepileptic drugs: teratogenicity and neonatal morbidityTarannum Musvee Lateef
Department of Neurology, Children s National Medical Center, Washington, DC 20010, USA
Curr Neurol Neurosci Rep 7:133-8. 2007..This review focuses on AED exposure during pregnancy and how it affects the risks of neonatal morbidity and major congenital malformations... - Who will deliver our grandchildren? Implications of cerebral palsy litigationAlastair MacLennan
Department of Obstetrics and Gynaecology, Women s and Children s Hospital, University of Adelaide, Adelaide, Australia
JAMA 294:1688-90. 2005 - Hypothermia for neonates with hypoxic-ischemic encephalopathyKarin B Nelson
N Engl J Med 354:1643-5; author reply 1643-5. 2006 - Diagnostic value of lumbar puncture in afebrile infants with suspected new-onset seizuresTarannum M Lateef
Department of Neurology, Children s National Medical Center and George Washington University School of Medicine, Washington, DC, USA
J Pediatr 153:140-2. 2008..We analyzed cerebrospinal fluid results in infants and found that lumbar puncture adds little diagnostic value to the evaluation of young, well-appearing infants presenting with possible new-onset seizures...