K B Nelson

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Can we prevent cerebral palsy?
    Karin B Nelson
    Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA
    N Engl J Med 349:1765-9. 2003
  2. ncbi request reprint The neurologically impaired child and alleged malpractice at birth
    K B Nelson
    Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA
    Neurol Clin 17:283-93. 1999
  3. ncbi request reprint Selected neurotrophins, neuropeptides, and cytokines: developmental trajectory and concentrations in neonatal blood of children with autism or Down syndrome
    Phillip G Nelson
    National Institute of Child Health and Development, Building 31, Room 2A25, Bethesda, MD 20892 2426, USA
    Int J Dev Neurosci 24:73-80. 2006
  4. ncbi request reprint Thimerosal and autism?
    Karin B Nelson
    Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892 1447, USA
    Pediatrics 111:674-9. 2003
  5. ncbi request reprint Stroke in newborn infants
    Karin B Nelson
    Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1447, USA
    Lancet Neurol 3:150-8. 2004
  6. ncbi request reprint Genetic polymorphisms and cerebral palsy in very preterm infants
    Karin B Nelson
    National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892 1447, and Children s Hospital and Research Center at Oakland, CA 94609 1673, USA
    Pediatr Res 57:494-9. 2005
  7. ncbi request reprint Thrombophilias, perinatal stroke, and cerebral palsy
    Karin B Nelson
    National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892 1447, USA
    Clin Obstet Gynecol 49:875-84. 2006
  8. ncbi request reprint Perinatal ischemic stroke
    Karin B Nelson
    National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892 1447, USA
    Stroke 38:742-5. 2007
  9. ncbi request reprint Is it HIE? And why that matters
    Karin B Nelson
    National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892, USA
    Acta Paediatr 96:1113-4. 2007
  10. doi request reprint Is cerebral palsy preventable?
    Karin B Nelson
    National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892 2540, USA
    Curr Opin Neurol 21:129-35. 2008

Detail Information

Publications38

  1. ncbi request reprint Can we prevent cerebral palsy?
    Karin B Nelson
    Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA
    N Engl J Med 349:1765-9. 2003
  2. ncbi request reprint The neurologically impaired child and alleged malpractice at birth
    K B Nelson
    Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA
    Neurol Clin 17:283-93. 1999
    ..There is no evidence that caesarean section can prevent cerebral palsy in term infants...
  3. ncbi request reprint Selected neurotrophins, neuropeptides, and cytokines: developmental trajectory and concentrations in neonatal blood of children with autism or Down syndrome
    Phillip G Nelson
    National Institute of Child Health and Development, Building 31, Room 2A25, Bethesda, MD 20892 2426, USA
    Int J Dev Neurosci 24:73-80. 2006
    ..We discuss interrelationships of VIP, NT-3 and IL-8 and their potential relevance to features of the neuropathology of autism or Down syndrome...
  4. ncbi request reprint Thimerosal and autism?
    Karin B Nelson
    Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892 1447, USA
    Pediatrics 111:674-9. 2003
  5. ncbi request reprint Stroke in newborn infants
    Karin B Nelson
    Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892 1447, USA
    Lancet Neurol 3:150-8. 2004
    ..There is much to be learned about the natural history of perinatal stroke, and there are as yet no evidence-based strategies for prevention or treatment...
  6. ncbi request reprint Genetic polymorphisms and cerebral palsy in very preterm infants
    Karin B Nelson
    National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892 1447, and Children s Hospital and Research Center at Oakland, CA 94609 1673, USA
    Pediatr Res 57:494-9. 2005
    ..We conclude that further study of genetic factors that may influence susceptibility to CP in very preterm infants is warranted...
  7. ncbi request reprint Thrombophilias, perinatal stroke, and cerebral palsy
    Karin B Nelson
    National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892 1447, USA
    Clin Obstet Gynecol 49:875-84. 2006
    ..This review discusses the clinical entity, perinatal stroke, and its relationship to thrombophilias, inherited and acquired, and to maternal and pregnancy factors...
  8. ncbi request reprint Perinatal ischemic stroke
    Karin B Nelson
    National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892 1447, USA
    Stroke 38:742-5. 2007
    ..Maternal and infant thrombophilias, genetic and acquired, play a role. Rarely is >1 child in a sibship affected, and environmental factors-substantially less studied, to date--are likely to be key determinants of risk...
  9. ncbi request reprint Is it HIE? And why that matters
    Karin B Nelson
    National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892, USA
    Acta Paediatr 96:1113-4. 2007
  10. doi request reprint Is cerebral palsy preventable?
    Karin B Nelson
    National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892 2540, USA
    Curr Opin Neurol 21:129-35. 2008
    ..To use evidence of good medical quality to update information on strategies for prevention of cerebral palsy, and on the success of these preventive efforts to date...
  11. doi request reprint Causative factors in cerebral palsy
    Karin B Nelson
    National Institute of Neurological Diseases and Stroke, National Institutes of Health, Bethesda, MD 20892 2540, USA
    Clin Obstet Gynecol 51:749-62. 2008
    ..The contribution of genetic vulnerabilities that interact with environmental stressors is an emerging aspect of our understanding of causative factors in CP...
  12. ncbi request reprint Neonatal cytokines and cerebral palsy in very preterm infants
    Karin B Nelson
    Neuroepidemiology Branch, National Institutes of Neurological Disorder and Stroke, Bethesda, MD 20892, USA
    Pediatr Res 53:600-7. 2003
    ..Inflammatory cytokines in neonatal blood of very premature infants did not distinguish those with later diagnoses of CP from control children...
  13. ncbi request reprint The epidemiology of cerebral palsy in term infants
    Karin B Nelson
    Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892 1447, USA
    Ment Retard Dev Disabil Res Rev 8:146-50. 2002
    ..There have not yet been studies examining whether medical interventions directed at infection or coagulation disorder can reduce the frequency of CP...
  14. ncbi request reprint Causes of cerebral palsy
    K B Nelson
    California Birth Defects Monitoring Program, California Department of Health Services, Emeryville, USA
    Curr Opin Pediatr 11:487-91. 1999
    ..Recognition of a broader set of causal possibilities encourages hope for new strategies for the prevention of cerebral palsy...
  15. ncbi request reprint Neuropeptides and neurotrophins in neonatal blood of children with autism or mental retardation
    K B Nelson
    National Institute of Neurological Diseases and Stroke, Bethesda, MD 20892 1447, USA
    Ann Neurol 49:597-606. 2001
    ..In autism and in a heterogeneous group of disorders of cognitive function, overexpression of certain neuropeptides and neurotrophins was observed in peripheral blood drawn in the first days of life...
  16. ncbi request reprint Selection of neonates for neuroprotective therapies: one set of criteria applied to a population
    K B Nelson
    Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA
    Arch Pediatr Adolesc Med 153:393-8. 1999
    ..To estimate the proportion of children with cerebral palsy (CP) who had signs of birth asphyxia" in the early hours of life, and to examine the nature of the illnesses in those infants...
  17. ncbi request reprint Overview: infection during pregnancy and neurologic outcome in the child
    Karin B Nelson
    Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892 1447, USA
    Ment Retard Dev Disabil Res Rev 8:1-2. 2002
  18. ncbi request reprint Infection, inflammation and the risk of cerebral palsy
    K B Nelson
    Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
    Curr Opin Neurol 13:133-9. 2000
    ..The mechanisms involved are not well understood and may differ in very immature versus term infants. Term infants exposed to maternal infection are predisposed to delivery room depression and neonatal encephalopathy...
  19. ncbi request reprint Congenital abnormalities among children with cerebral palsy: More evidence for prenatal antecedents
    L A Croen
    March of Dimes Birth Defects Foundation, California Department of Health Services, California Birth Defects Monitoring Program, Oakland, CA, USA
    J Pediatr 138:804-10. 2001
    ..CONCLUSION: These findings provide further evidence that factors operating in the prenatal period contribute significantly to the etiology of CP...
  20. ncbi request reprint Intrauterine exposure to infection and risk of cerebral palsy in very preterm infants
    Judith K Grether
    California Birth Defects Monitoring Program, California Department of Health Services, Oakland, CA, USA
    Arch Pediatr Adolesc Med 157:26-32. 2003
    ..To evaluate exposure to intrauterine infection as an independent risk factor for spastic cerebral palsy (CP) among very prematurely born infants...
  21. ncbi request reprint Epidemiology of perinatal stroke
    J K Lynch
    Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA
    Curr Opin Pediatr 13:499-505. 2001
    ....
  22. ncbi request reprint Cerebrovascular disorders in children with the factor V Leiden mutation
    J K Lynch
    Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA
    J Child Neurol 16:735-44. 2001
    ..This mutation should be considered in the evaluation of children with a stroke or its sequelae, including infants with perinatal stroke...
  23. doi request reprint The placenta and neurologic and psychiatric outcomes in the child: study design matters
    K B Nelson
    Department of Neurology, Children s National Medical Center, Washington, DC, USA
    Placenta 32:623-5. 2011
    ..A new generation of studies, difficult but potentially enormously rewarding, will be needed for clinical investigations of the placenta and fetal brain development...
  24. pmc Headache and biomarkers predictive of vascular disease in a representative sample of US children
    Karin B Nelson
    National Institute of Neurological Disorders and Stroke, Bldg 31, Room 8A03, Bethesda, MD 20892 2450, USA
    Arch Pediatr Adolesc Med 164:358-62. 2010
    ..To examine the association of childhood headache disorders with markers of risk for cardiovascular and cerebrovascular disease...
  25. ncbi request reprint Ischemic perinatal stroke: summary of a workshop sponsored by the National Institute of Child Health and Human Development and the National Institute of Neurological Disorders and Stroke
    Tonse N K Raju
    National Institute of Child Health and Human Development, Bethesda, MD 20892, USA
    Pediatrics 120:609-16. 2007
    ..This article provides a summary of the workshop...
  26. ncbi request reprint The risk of mortality or cerebral palsy in twins: a collaborative population-based study
    Ann I Scher
    Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Pediatr Res 52:671-81. 2002
    ..Co-twin death was a strong predictor of CP in surviving twins. This risk was the same for same- and different-sex pairs, and observed both for preterm and term infants...
  27. ncbi request reprint Report of the National Institute of Neurological Disorders and Stroke workshop on perinatal and childhood stroke
    John Kylan Lynch
    Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA
    Pediatrics 109:116-23. 2002
    ..The impact of maternal and perinatal factors on risk and outcome of neonatal stroke needs to be studied. This information is essential to identifying significant areas for future treatment and prevention...
  28. ncbi request reprint Prothrombotic factors in children with stroke or porencephaly
    John Kylan Lynch
    National Institute of Neurological Disorders and Stroke, Building 10, Room 5S220, 10 Center Dr, MSC 1447, Bethesda, MD 20892 1447, USA
    Pediatrics 116:447-53. 2005
    ..This study compared the frequencies of genetic and functional coagulation abnormalities in children with arterial ischemic stroke or porencephaly with frequencies in previously published studies...
  29. ncbi request reprint How common are gastrointestinal disorders in children with autism?
    Thea Kuddo
    Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892, USA
    Curr Opin Pediatr 15:339-43. 2003
    ....
  30. ncbi request reprint Neonatal encephalopathy: etiology and outcome
    Karin B Nelson
    Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, USA
    Dev Med Child Neurol 47:292. 2005
  31. ncbi request reprint Genetic polymorphisms and spontaneous preterm birth
    Catherine S Gibson
    School of Paediatrics and Reproductive Health, University of Adelaide, Adelaide, Australia
    Obstet Gynecol 109:384-91. 2007
    ..To examine whether selected genetic polymorphisms in the infant are associated with spontaneous preterm birth (less than 37 weeks) among children with or without later-diagnosed cerebral palsy...
  32. ncbi request reprint 'Defining hypoxic-ischemic birth events'
    Karin B Nelson
    Dev Med Child Neurol 45:71; author reply 71-2. 2003
  33. ncbi request reprint Chorioamnionitis and brain injury
    Rodney E Willoughby
    Eudowood Division of Pediatric Infectious Diseases, Department of Pediatrics, Johns Hopkins University, 600 N Wolfe St, Park 256, Baltimore, MD 21287 4933, USA
    Clin Perinatol 29:603-21. 2002
    ....
  34. ncbi request reprint Perinatal arterial stroke: understanding mechanisms and outcomes
    Yvonne W Wu
    Department of Neurology, University of California San Francisco, San Francisco, California 94117, USA
    Semin Neurol 25:424-34. 2005
    ..The incidence, clinical presentation, pathogenesis, risk factors, and outcome of this increasingly recognized disorder are reviewed...
  35. ncbi request reprint In utero exposure to antiepileptic drugs: teratogenicity and neonatal morbidity
    Tarannum Musvee Lateef
    Department of Neurology, Children s National Medical Center, Washington, DC 20010, USA
    Curr Neurol Neurosci Rep 7:133-8. 2007
    ..This review focuses on AED exposure during pregnancy and how it affects the risks of neonatal morbidity and major congenital malformations...
  36. ncbi request reprint Who will deliver our grandchildren? Implications of cerebral palsy litigation
    Alastair MacLennan
    Department of Obstetrics and Gynaecology, Women s and Children s Hospital, University of Adelaide, Adelaide, Australia
    JAMA 294:1688-90. 2005
  37. ncbi request reprint Hypothermia for neonates with hypoxic-ischemic encephalopathy
    Karin B Nelson
    N Engl J Med 354:1643-5; author reply 1643-5. 2006
  38. doi request reprint Diagnostic value of lumbar puncture in afebrile infants with suspected new-onset seizures
    Tarannum M Lateef
    Department of Neurology, Children s National Medical Center and George Washington University School of Medicine, Washington, DC, USA
    J Pediatr 153:140-2. 2008
    ..We analyzed cerebrospinal fluid results in infants and found that lumbar puncture adds little diagnostic value to the evaluation of young, well-appearing infants presenting with possible new-onset seizures...