Howard A Nash

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint An unusual cation channel mediates photic control of locomotion in Drosophila
    Howard A Nash
    Laboratory of Molecular Biology, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    Curr Biol 12:2152-8. 2002
  2. pmc Genetic effects in Drosophila on the potency of diverse general anesthetics: a distinctive pattern of altered sensitivity
    Joseph L Campbell
    Laboratory of Molecular Biology, National Institute of Mental Health, Bethesda, MD 20892 3736, USA
    J Neurogenet 23:412-21. 2009
  3. pmc Visual mutations reveal opposing effects of illumination on arousal in Drosophila
    Yuzhong Cheng
    Laboratory of Molecular Biology, National Institutes of Mental Health, Bethesda, Maryland 20892 3736, USA
    Genetics 178:2413-6. 2008
  4. pmc Impact of gene copy number variation on anesthesia in Drosophila melanogaster
    Debasmita P Alone
    Laboratory of Molecular Biology, National Institute of Mental Health, Bethesda, Maryland 20892 3736, USA
    Anesthesiology 111:15-24. 2009
  5. pmc The mushroom body defect gene product is an essential component of the meiosis II spindle apparatus in Drosophila oocytes
    James X Yu
    Laboratory of Molecular Biology, NIMH, Bethesda, Maryland 20892 3736, USA
    Genetics 173:243-53. 2006
  6. pmc Drosophila TRP channels require a protein with a distinctive motif encoded by the inaF locus
    Yuzhong Cheng
    Laboratory of Molecular Biology, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 104:17730-4. 2007
  7. pmc Retrograde signaling from the brain to the retina modulates the termination of the light response in Drosophila
    Shantadurga Rajaram
    Laboratory of Molecular Biology, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 3736, USA
    Proc Natl Acad Sci U S A 102:17840-5. 2005
  8. ncbi request reprint The role of TDP1 from budding yeast in the repair of DNA damage
    Chunyan Liu
    Laboratory of Molecular Biology, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892 4034, USA
    DNA Repair (Amst) 3:593-601. 2004
  9. ncbi request reprint A putative cation channel and its novel regulator: cross-species conservation of effects on general anesthesia
    John A Humphrey
    Department of Genetics, Case Medical Center, Cleveland, OH 44106, USA
    Curr Biol 17:624-9. 2007

Collaborators

  • Yuzhong Cheng
  • Joseph L Campbell
  • Debasmita P Alone
  • John A Humphrey
  • Robert L Scott
  • James X Yu
  • Shantadurga Rajaram
  • Chunyan Liu
  • Dongyu Guo
  • Cameron L Noland
  • Qun Gu
  • Jason C Rodriguez
  • Phil G Morgan
  • Margaret M Sedensky
  • Colin M Thacker
  • Kevin S Hamming
  • Terrance P Snutch
  • Zhonghui Guan
  • Jeffrey J Pouliot

Detail Information

Publications9

  1. ncbi request reprint An unusual cation channel mediates photic control of locomotion in Drosophila
    Howard A Nash
    Laboratory of Molecular Biology, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    Curr Biol 12:2152-8. 2002
    ..The involvement of the channel in daily rhythms of the fruit fly is especially provocative because the human ortholog lies in a candidate region linked to bipolar disorder, a disease frequently associated with altered diurnal behavior...
  2. pmc Genetic effects in Drosophila on the potency of diverse general anesthetics: a distinctive pattern of altered sensitivity
    Joseph L Campbell
    Laboratory of Molecular Biology, National Institute of Mental Health, Bethesda, MD 20892 3736, USA
    J Neurogenet 23:412-21. 2009
    ..Intriguingly, P element insertions that co-map with several NEP loci have been shown to alter the fly's response to cocaine and ethanol, suggesting that common genetic elements are involved in the response to all three drugs...
  3. pmc Visual mutations reveal opposing effects of illumination on arousal in Drosophila
    Yuzhong Cheng
    Laboratory of Molecular Biology, National Institutes of Mental Health, Bethesda, Maryland 20892 3736, USA
    Genetics 178:2413-6. 2008
    ..These dual effects may explain aspects of the fly's daily activity and have potential clinical implications...
  4. pmc Impact of gene copy number variation on anesthesia in Drosophila melanogaster
    Debasmita P Alone
    Laboratory of Molecular Biology, National Institute of Mental Health, Bethesda, Maryland 20892 3736, USA
    Anesthesiology 111:15-24. 2009
    ..Phenotypic effects of copy number variation are commonly observed, but effects on sensitivity to volatile anesthetics have not been assessed in any organism...
  5. pmc The mushroom body defect gene product is an essential component of the meiosis II spindle apparatus in Drosophila oocytes
    James X Yu
    Laboratory of Molecular Biology, NIMH, Bethesda, Maryland 20892 3736, USA
    Genetics 173:243-53. 2006
    ..But the commonalities in its location suggest potential roles for the protein in development of other tissues...
  6. pmc Drosophila TRP channels require a protein with a distinctive motif encoded by the inaF locus
    Yuzhong Cheng
    Laboratory of Molecular Biology, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 104:17730-4. 2007
    ..Given the role of INAF-B, these proteins are good candidates for interacting partners of other members of the TRP superfamily...
  7. pmc Retrograde signaling from the brain to the retina modulates the termination of the light response in Drosophila
    Shantadurga Rajaram
    Laboratory of Molecular Biology, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 3736, USA
    Proc Natl Acad Sci U S A 102:17840-5. 2005
    ..Although the mechanism of this retrograde signaling remains to be discerned, the phenomenon establishes a previously unappreciated mode of control of the temporal responsiveness of a primary sensory neuron...
  8. ncbi request reprint The role of TDP1 from budding yeast in the repair of DNA damage
    Chunyan Liu
    Laboratory of Molecular Biology, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892 4034, USA
    DNA Repair (Amst) 3:593-601. 2004
    ..The relationship between the role of TDP1 in Saccharomyces and its role in metazoans is discussed...
  9. ncbi request reprint A putative cation channel and its novel regulator: cross-species conservation of effects on general anesthesia
    John A Humphrey
    Department of Genetics, Case Medical Center, Cleveland, OH 44106, USA
    Curr Biol 17:624-9. 2007
    ..Thus, the anesthetic signature reflects an evolutionarily conserved role for the na orthologs, implying its intimate involvement in drug action...