Nakayamada S, Takahashi H, Kanno Y, O Shea J. Helper T cell diversity and plasticity. Curr Opin Immunol. 2012;24:297-302 pubmed publisher
..In this review, we highlight recent advances that pertain to this topic and the mechanisms that contribute to helper CD4(+) T cell differentiation and plasticity. ..
Nakayamada S, Kanno Y, Takahashi H, Jankovic D, Lu K, Johnson T, et al. Early Th1 cell differentiation is marked by a Tfh cell-like transition. Immunity. 2011;35:919-31 pubmed publisher
..Our data argue that Tfh and Th1 cells share a transitional stage through the signal mediated by STAT4, which promotes both phenotypes. However, T-bet represses Tfh cell functionalities, promoting full Th1 cell differentiation. ..