Research Topics
Genomes and GenesSpecies | Gwen MurphySummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Serum ghrelin is inversely associated with risk of subsequent oesophageal squamous cell carcinomaGwen Murphy
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20892, USA
Gut 61:1533-7. 2012..Ghrelin, a hormone which, is also produced in the gastric fundic glands may be a marker of gastric atrophy, but its association with OSCC is not known...
The relationship between serum ghrelin and the risk of gastric and esophagogastric junctional adenocarcinomasGwen Murphy
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 3034, Rockville, MD 20892, USA
J Natl Cancer Inst 103:1123-9. 2011..However, the relationship between ghrelin and the risk of gastric and esophagogastric junctional cancers has not been investigated...
Prospective study of serum cysteine levels and oesophageal and gastric cancers in ChinaGwen Murphy
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
Gut 60:618-23. 2011..To examine the relationship between serum cysteine concentration and risk of these cancers we conducted a nested case-cohort study within the General Population Nutrition Intervention Trial in Linxian, China...
Sex disparities in colorectal cancer incidence by anatomic subsite, race and ageGwen Murphy
Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD
Int J Cancer 128:1668-75. 2011..These findings may partially reflect differences in screening experiences and access to medical care but also suggest that etiologic factors may be playing a role...
Meta-analysis shows that prevalence of Epstein-Barr virus-positive gastric cancer differs based on sex and anatomic locationGwen Murphy
Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute, NIH, Rockville, Maryland 20892, USA
Gastroenterology 137:824-33. 2009..However, the proportion of EBV-positive gastric carcinomas is uncertain, and the etiologic significance is unknown...
Family cancer history affecting risk of colorectal cancer in a prospective cohort of Chinese womenGwen Murphy
Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
Cancer Causes Control 20:1517-21. 2009..Our cohort results suggest that consistent with findings from Western populations, having a family history of colorectal cancer may influence colorectal cancer risk to a similar extent in a low-risk population...
Dopamine D2 receptor polymorphisms and adenoma recurrence in the Polyp Prevention TrialGwen Murphy
Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute, Bethesda, MD 20892, USA
Int J Cancer 124:2148-51. 2009..Increased risk of adenoma recurrence as conferred by DRD2 genotypes may be related to difference in alcohol and fat intake across genotypes...
Polynucleotide kinase 3' phosphatase variant, dietary variables and risk of adenoma recurrence in the Polyp Prevention TrialGwen Murphy
Cancer Prevention Fellowship Program, Office of Preventive Oncology, Bethesda, Maryland, USA
Eur J Cancer Prev 17:287-90. 2008..Furthermore, we found no effect modification between genotype, dietary components and risk of adenoma recurrence. The PNKP T5644G variant does not seem to be involved in adenoma recurrence in the Polyp Prevention Trial...
Folate and MTHFR: risk of adenoma recurrence in the Polyp Prevention TrialGwen Murphy
Cancer Prevention Fellowship Program, Office of Preventive Oncology, Bethesda, MD, USA
Cancer Causes Control 19:751-8. 2008..A C/T transition at position 677 in the gene encoding methlylenetetrahydrofolate reductase (MTHFR C677T) has been reported to interact with folate intake to modulate colorectal adenoma recurrence or cancer risk...
Postpolypectomy colonoscopy surveillance guidelines: predictive accuracy for advanced adenoma at 4 yearsAdeyinka O Laiyemo
Cancer Prevention Fellowship Program, Biometry Research Group, Divisionof Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Ann Intern Med 148:419-26. 2008..Lack of confidence in postpolypectomy surveillance guidelines may be a factor in the observed low adherence rates among providers...
Dietary lignan and proanthocyanidin consumption and colorectal adenoma recurrence in the Polyp Prevention TrialGerd Bobe
Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute NCI, National Institutes of Health NIH, Department of Health and Human Services DHHS, Frederick, MD, USA
Int J Cancer 130:1649-59. 2012..04). To conclude, dietary lignan and proanthocyanidin consumption were not generally related to colorectal adenoma recurrence; however, high lignan intake may increase the risk of adenoma recurrence in women...
Hyperplastic polyps and the risk of adenoma recurrence in the polyp prevention trialAdeyinka O Laiyemo
Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute, Bethesda, Maryland 20892, USA
Clin Gastroenterol Hepatol 7:192-7. 2009..Prospective information on the risk of adenoma recurrence associated with hyperplastic polyps is limited. We sought to investigate whether the coexistence of hyperplastic polyps with adenomas increases the risk of adenoma recurrence...
Serum adiponectin, leptin, C-peptide, homocysteine, and colorectal adenoma recurrence in the Polyp Prevention TrialGerd Bobe
Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute NCI, NIH, Department of Health and Human Services DHHS, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 19:1441-52. 2010..Serum adiponectin, leptin, C-peptide, and homocysteine are indicators for obesity, hyperinsulinemia, and chronic inflammation, which have all been associated with colorectal cancer...
Do interleukin polymorphisms play a role in the prevention of colorectal adenoma recurrence by dietary flavonols?Gerd Bobe
Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Eur J Cancer Prev 20:86-95. 2011..In conclusion, our results suggest that IL SNPs, in combination with a flavonol-rich diet or decreased serum IL, may lower the risk of adenoma recurrence...
Association of gastric disease with polymorphisms in the inflammatory-related genes IL-1B, IL-1RN, IL-10, TNF and TLR4Gwen Murphy
Cancer Prevention Fellowship Program, Office of Preventive Oncology and Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
Eur J Gastroenterol Hepatol 21:630-5. 2009..pylori)-associated gastritis and intestinal metaplasia...
The polyp prevention trial continued follow-up study: no effect of a low-fat, high-fiber, high-fruit, and -vegetable diet on adenoma recurrence eight years after randomizationElaine Lanza
Laboratory for Cancer Prevention, Centre for Cancer Research, National Cancer Institute, 6116 Executive Boulevard, Room 7206, Bethesda, MD 20892 8325, USA
Cancer Epidemiol Biomarkers Prev 16:1745-52. 2007..04 (0.98-1.09). This study failed to show any effect of a low-fat, high-fiber, high-fruit and -vegetable eating pattern on adenoma recurrence even with 8 years of follow-up. (Cancer Epidemiol Biomarkers Prev 2007;16(9):1745-52)...
Height at diagnosis and birth-weight as risk factors for osteosarcomaLisa Mirabello
Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Cancer Causes Control 22:899-908. 2011..Osteosarcoma typically occurs during puberty. Studies of the association between height and/or birth-weight and osteosarcoma are conflicting. Therefore, we conducted a large pooled analysis of height and birth-weight in osteosarcoma...
