Ranganath Muniyappa

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Limited predictive ability of surrogate indices of insulin sensitivity/resistance in Asian-Indian men
    Ranganath Muniyappa
    Diabetes Unit, NCCAM, NIH, Bethesda, MD 20892 0920, USA
    Am J Physiol Endocrinol Metab 299:E1106-12. 2010
  2. pmc Metabolic actions of angiotensin II and insulin: a microvascular endothelial balancing act
    Ranganath Muniyappa
    Clinical Endocrine Section, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, United States Electronic address
    Mol Cell Endocrinol 378:59-69. 2013
  3. pmc Diurnal secretion of growth hormone, cortisol, and dehydroepiandrosterone in pre- and perimenopausal women with active rheumatoid arthritis: a pilot case-control study
    Marc R Blackman
    Endocrine Section, Laboratory of Clinical Investigation, National Center for Complementary and Alternative Medicine, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Arthritis Res Ther 9:R73. 2007
  4. pmc Postprandial endothelial function does not differ in women by race: an insulin resistance paradox?
    Ranganath Muniyappa
    Diabetes, Endocrinology, and Obesity Branch, Intramural Program, National Institute of Diabetes and Digestive and Kidney Diseases NIH, 10 Center Drive, Bethesda, MD 20892 0920, USA
    Am J Physiol Endocrinol Metab 302:E218-25. 2012
  5. pmc Comparison between surrogate indexes of insulin sensitivity/resistance and hyperinsulinemic euglycemic clamp estimates in rats
    Ranganath Muniyappa
    Diabetes Unit, NCCAM, NIH, 9 Memorial Dr, Bldg 9, Rm 1N 105 MSC 0920, Bethesda, MD 20892 0920, USA
    Am J Physiol Endocrinol Metab 297:E1023-9. 2009
  6. pmc Cocoa consumption for 2 wk enhances insulin-mediated vasodilatation without improving blood pressure or insulin resistance in essential hypertension
    Ranganath Muniyappa
    Diabetes Unit, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, MD, USA
    Am J Clin Nutr 88:1685-96. 2008
  7. ncbi request reprint Insulin action and insulin resistance in vascular endothelium
    Ranganath Muniyappa
    Diabetes Unit, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland 20892 1632, USA
    Curr Opin Clin Nutr Metab Care 10:523-30. 2007
  8. pmc Comparison between surrogate indexes of insulin sensitivity/resistance and hyperinsulinemic euglycemic glucose clamps in rhesus monkeys
    Ho Won Lee
    Diabetes Unit, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland 20892, USA
    Endocrinology 152:414-23. 2011
  9. ncbi request reprint Comparison between surrogate indexes of insulin sensitivity and resistance and hyperinsulinemic euglycemic clamp estimates in mice
    Sihoon Lee
    Diabetes Unit, National Center for Complementary and Alternative Medicine, National Institutes of Health, 9 Memorial Drive, Bethesda, MD 20892 0920, USA
    Am J Physiol Endocrinol Metab 294:E261-70. 2008
  10. pmc Reduced insulin sensitivity in adults with pseudohypoparathyroidism type 1a
    Ranganath Muniyappa
    MD, Chief, Clinical Endocrine Section, Diabetes, Endocrinology, and Obesity Branch, National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 10 Center Drive MSC 1613, Building 10, CRC, room 6 3940, Bethesda, Maryland 20892 1613
    J Clin Endocrinol Metab 98:E1796-801. 2013

Detail Information

Publications22

  1. pmc Limited predictive ability of surrogate indices of insulin sensitivity/resistance in Asian-Indian men
    Ranganath Muniyappa
    Diabetes Unit, NCCAM, NIH, Bethesda, MD 20892 0920, USA
    Am J Physiol Endocrinol Metab 299:E1106-12. 2010
    ....
  2. pmc Metabolic actions of angiotensin II and insulin: a microvascular endothelial balancing act
    Ranganath Muniyappa
    Clinical Endocrine Section, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, United States Electronic address
    Mol Cell Endocrinol 378:59-69. 2013
    ....
  3. pmc Diurnal secretion of growth hormone, cortisol, and dehydroepiandrosterone in pre- and perimenopausal women with active rheumatoid arthritis: a pilot case-control study
    Marc R Blackman
    Endocrine Section, Laboratory of Clinical Investigation, National Center for Complementary and Alternative Medicine, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Arthritis Res Ther 9:R73. 2007
    ..Whether these changes contribute to rheumatoid cachexia remains to be determined. Trial registration number: NCT00034060...
  4. pmc Postprandial endothelial function does not differ in women by race: an insulin resistance paradox?
    Ranganath Muniyappa
    Diabetes, Endocrinology, and Obesity Branch, Intramural Program, National Institute of Diabetes and Digestive and Kidney Diseases NIH, 10 Center Drive, Bethesda, MD 20892 0920, USA
    Am J Physiol Endocrinol Metab 302:E218-25. 2012
    ..These results imply that insulin sensitivity may not be an important determinant of racial differences in endothelial function...
  5. pmc Comparison between surrogate indexes of insulin sensitivity/resistance and hyperinsulinemic euglycemic clamp estimates in rats
    Ranganath Muniyappa
    Diabetes Unit, NCCAM, NIH, 9 Memorial Dr, Bldg 9, Rm 1N 105 MSC 0920, Bethesda, MD 20892 0920, USA
    Am J Physiol Endocrinol Metab 297:E1023-9. 2009
    ..However, use of surrogates may be appropriate in rodents, where feasibility of clamps is an obstacle and measurement of insulin sensitivity is a secondary outcome...
  6. pmc Cocoa consumption for 2 wk enhances insulin-mediated vasodilatation without improving blood pressure or insulin resistance in essential hypertension
    Ranganath Muniyappa
    Diabetes Unit, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, MD, USA
    Am J Clin Nutr 88:1685-96. 2008
    ..Essential hypertension is characterized by reciprocal relations between endothelial dysfunction and insulin resistance. Cocoa flavanols stimulate production of the vasodilator nitric oxide from vascular endothelium...
  7. ncbi request reprint Insulin action and insulin resistance in vascular endothelium
    Ranganath Muniyappa
    Diabetes Unit, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland 20892 1632, USA
    Curr Opin Clin Nutr Metab Care 10:523-30. 2007
    ..Here we discuss consequences of pathway-specific insulin resistance in endothelium and therapeutic interventions targeting this selective impairment...
  8. pmc Comparison between surrogate indexes of insulin sensitivity/resistance and hyperinsulinemic euglycemic glucose clamps in rhesus monkeys
    Ho Won Lee
    Diabetes Unit, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland 20892, USA
    Endocrinology 152:414-23. 2011
    ....
  9. ncbi request reprint Comparison between surrogate indexes of insulin sensitivity and resistance and hyperinsulinemic euglycemic clamp estimates in mice
    Sihoon Lee
    Diabetes Unit, National Center for Complementary and Alternative Medicine, National Institutes of Health, 9 Memorial Drive, Bethesda, MD 20892 0920, USA
    Am J Physiol Endocrinol Metab 294:E261-70. 2008
    ..This may reflect intrinsic differences between human and rodent physiology as well as increased technical difficulties in performing glucose clamps in mice...
  10. pmc Reduced insulin sensitivity in adults with pseudohypoparathyroidism type 1a
    Ranganath Muniyappa
    MD, Chief, Clinical Endocrine Section, Diabetes, Endocrinology, and Obesity Branch, National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 10 Center Drive MSC 1613, Building 10, CRC, room 6 3940, Bethesda, Maryland 20892 1613
    J Clin Endocrinol Metab 98:E1796-801. 2013
    ..However, insulin resistance and glucose metabolism have not been systematically characterized in patients with PHP1a...
  11. pmc An integrated view of insulin resistance and endothelial dysfunction
    Ranganath Muniyappa
    Diabetes Unit, National Center for Complementary and Alternative Medicine, National Institutes of Health, 10 Center Drive, 10 CRC, Room 4 1741, Bethesda, MD 20892 1632, USA
    Endocrinol Metab Clin North Am 37:685-711, ix-x. 2008
    ....
  12. ncbi request reprint Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage
    Ranganath Muniyappa
    Diabetes Unit, National Center for Complementary and Alternative Medicine, National Institutes of Health, 9 Memorial Drive, Bldg 9, Rm 1N 105 MSC 0920, Bethesda, MD 20892, USA
    Am J Physiol Endocrinol Metab 294:E15-26. 2008
    ..In this Frontiers article, we highlight merits, limitations, and appropriate use of current in vivo measures of insulin sensitivity/resistance...
  13. ncbi request reprint Cardiovascular actions of insulin
    Ranganath Muniyappa
    Diabetes Unit, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland 20892 1632, USA
    Endocr Rev 28:463-91. 2007
    ....
  14. ncbi request reprint Effects of chronic osteoarthritis pain on neuroendocrine function in men
    Suzan Khoromi
    Laboratory of Clinical Investigation, Division of Intramural Research, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland 20892 1302, USA
    J Clin Endocrinol Metab 91:4313-8. 2006
    ..Most endocrine studies have been conducted in patients in whom the potentially confounding effects of depression, inflammatory disease, or coexistent medication use have not been controlled...
  15. pmc Epigallocatechin gallate induces expression of heme oxygenase-1 in endothelial cells via p38 MAPK and Nrf-2 that suppresses proinflammatory actions of TNF-α
    Philomena Pullikotil
    Diabetes Unit, National Center for Complementary and Alternative Medicine, Bethesda, MD 20892, USA
    J Nutr Biochem 23:1134-45. 2012
    ..Increased HO-1 expression may underlie anti-inflammatory actions of EGCG in vascular endothelium that may help mediate beneficial cardiovascular actions of green tea...
  16. pmc Metabolic effects of chronic cannabis smoking
    Ranganath Muniyappa
    Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland, USA
    Diabetes Care 36:2415-22. 2013
    ..We examined if chronic cannabis smoking is associated with hepatic steatosis, insulin resistance, reduced β-cell function, or dyslipidemia in healthy individuals...
  17. pmc Role of insulin resistance in endothelial dysfunction
    Ranganath Muniyappa
    Clinical Endocrine Section, Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA
    Rev Endocr Metab Disord 14:5-12. 2013
    ....
  18. pmc Effects of testosterone administration on nocturnal cortisol secretion in healthy older men
    Ranganath Muniyappa
    Diabetes Unit, Laboratory of Clinical Investigation, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland, USA
    J Gerontol A Biol Sci Med Sci 65:1185-92. 2010
    ..We conclude that low-dose testosterone supplementation for 26 weeks does not affect spontaneous nocturnal cortisol secretion in healthy older men...
  19. ncbi request reprint Oral glucosamine for 6 weeks at standard doses does not cause or worsen insulin resistance or endothelial dysfunction in lean or obese subjects
    Ranganath Muniyappa
    Chief, Diabetes Unit, National Center for Complementary and Alternative Medicine, National Institutes of Health, 10 Center Dr, Bldg 10, Rm 6C 205, Bethesda, MD 20892, USA
    Diabetes 55:3142-50. 2006
    ..We conclude that oral glucosamine at standard doses for 6 weeks does not cause or significantly worsen insulin resistance or endothelial dysfunction in lean or obese subjects...
  20. ncbi request reprint Dehydroepiandrosterone secretion in healthy older men and women: effects of testosterone and growth hormone administration in older men
    Ranganath Muniyappa
    Endocrine Section, Laboratory of Clinical Investigation, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Clin Endocrinol Metab 91:4445-52. 2006
    ....
  21. ncbi request reprint Long-term testosterone supplementation augments overnight growth hormone secretion in healthy older men
    Ranganath Muniyappa
    Endocrine Section, Laboratory of Clinical Investigation, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, Maryland, USA
    Am J Physiol Endocrinol Metab 293:E769-75. 2007
    ..02), with no significant change in IGFBP-3 levels after T vs. placebo. We conclude that low-dose T supplementation for 26 wk increases spontaneous nocturnal GH secretion and morning serum IGF-I concentrations in healthy older men...