Yoh suke Mukouyama
Affiliation: National Institutes of Health
Mukouyama Y, James J, Nam J, Uchida Y. Whole-mount confocal microscopy for vascular branching morphogenesis. Methods Mol Biol. 2012;843:69-78 pubmed publisher
..Laser scanning confocal microscopy with multiple labeling allows for robust imaging of blood and lymphatic vessel branching morphogenesis with excellent resolution. ..
Sandeep N, Uchida Y, Ratnayaka K, McCarter R, Hanumanthaiah S, Bangoura A, et al
. Characterizing the angiogenic activity of patients with single ventricle physiology and aortopulmonary collateral vessels. J Thorac Cardiovasc Surg. 2016;151:1126-35.e2 pubmed publisher
..Plasma factors and angiogenic activity correlate poorly with aortopulmonary collateral severity in patients with single ventricles, suggesting complex mechanisms of angiogenesis. ..
Yamazaki T, Li W, Yang L, Li P, Cao H, Motegi S, et al
. Whole-Mount Adult Ear Skin Imaging Reveals Defective Neuro-Vascular Branching Morphogenesis in Obese and Type 2 Diabetic Mouse Models. Sci Rep. 2018;8:430 pubmed publisher
..These data suggest that our whole-mount imaging method enables us to investigate the neuro-vascular and neuro-immune phenotypes in the animal models of obesity and diabetes. ..
Uchida Y, James J, Suto F, Mukouyama Y. Class 3 semaphorins negatively regulate dermal lymphatic network formation. Biol Open. 2015;4:1194-205 pubmed publisher
..The reciprocal phenotype in lymphatic branching between Sema3f;Sema3g double mutants and Nrp2 mutants suggest a complex NRP2 function that regulates LEC behavior both positively and negatively, through a binding with VEGFC or SEMA3s. ..
Yamazaki T, Nalbandian A, Uchida Y, Li W, Arnold T, Kubota Y, et al
. Tissue Myeloid Progenitors Differentiate into Pericytes through TGF-Î² Signaling in Developing Skin Vasculature. Cell Rep. 2017;18:2991-3004 pubmed publisher
..Combined, these data suggest that pericytes differentiate from tissue myeloid progenitors in the skin vasculature through TGF-Î² signaling. ..
Sato Y, Uchida Y, Hu J, Young Pearse T, Niikura T, Mukouyama Y. Soluble APP functions as a vascular niche signal that controls adult neural stem cell number. Development. 2017;144:2730-2736 pubmed publisher
..Taken together, these results suggest that endothelial APP functions as a vascular niche signal that negatively regulates NSC growth to control the NSC number in the SVZ. ..