Research Topics
| David M MorensSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Characterizing a "new" disease: epizootic and epidemic anthrax, 1769-1780David M Morens
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 6603, USA
Am J Public Health 93:886-93. 2003..If such processes have operated over 2 or more centuries, studying them may yield clues about desirable interactions between epidemiology/public health and experimental science in the characterization of new diseases...
Dengue and hemorrhagic fever: a potential threat to public health in the United StatesDavid M Morens
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
JAMA 299:214-6. 2008
Cross-species virus transmission and the emergence of new epidemic diseasesColin R Parrish
Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Microbiol Mol Biol Rev 72:457-70. 2008....
Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: implications for pandemic influenza preparednessDavid M Morens
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
J Infect Dis 198:962-70. 2008..Despite the availability of published data on 4 pandemics that have occurred over the past 120 years, there is little modern information on the causes of death associated with influenza pandemics...
The 1918 influenza pandemic: lessons for 2009 and the futureDavid M Morens
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
Crit Care Med 38:e10-20. 2010..Thus, we must remain vigilant and use the knowledge we have gained from 1918 and other influenza pandemics to direct targeted research and pandemic influenza preparedness planning, emphasizing prevention, containment, and treatment...
Discovery and characterization of the 1918 pandemic influenza virus in historical contextJeffery K Taubenberger
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
Antivir Ther 12:581-91. 2007....
Influenza: the once and future pandemicJeffery K Taubenberger
Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 33 North Dr, Rm 3E19A 2, MSC 3203, Bethesda, MD 20892 3203, USA
Public Health Rep 125:16-26. 2010..Influenza pandemics have been reported for at least 500 years, with inter-pandemic intervals averaging approximately 40 years...
Autopsy series of 68 cases dying before and during the 1918 influenza pandemic peakZong Mei Sheng
Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
Proc Natl Acad Sci U S A 108:16416-21. 2011..These findings have important implications for understanding the origins and evolution of pandemic influenza viruses...
Historical thoughts on influenza viral ecosystems, or behold a pale horse, dead dogs, failing fowl, and sick swineDavid M Morens
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
Influenza Other Respi Viruses 4:327-37. 2010..To understand human influenza in a historical context of viral circulation in avian species, mammals, and in the environment...
The next influenza pandemic: can it be predicted?Jeffery K Taubenberger
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 2520, USA
JAMA 297:2025-7. 2007
An avian outbreak associated with panzootic equine influenza in 1872: an early example of highly pathogenic avian influenza?David M Morens
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
Influenza Other Respi Viruses 4:373-7. 2010..To our knowledge the scientific literature contains no mention of the nationwide 1872 poultry outbreak...
Emerging infections: a perpetual challengeDavid M Morens
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
Lancet Infect Dis 8:710-9. 2008..Fundamental determinants, typically acting in concert, seem to underlie their emergence, and infections such as these are likely to continue to remain challenges to human survival...
Prior infection with classical swine H1N1 influenza viruses is associated with protective immunity to the 2009 pandemic H1N1 virusJohn C Kash
Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, Bethesda, MD 20892 3203, USA
Influenza Other Respi Viruses 4:121-7. 2010..Epidemiological evidence suggested that the current seasonal vaccine did not offer significant protection from the novel pandemic, and that people over the age of 50 were less susceptible to infection...
Protection against a lethal H5N1 influenza challenge by intranasal immunization with virus-like particles containing 2009 pandemic H1N1 neuraminidase in miceJudith D Easterbrook
Viral Pathogenesis and Evolution Section, Laboratory of Infectious Diseases, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 3203, USA
Virology 432:39-44. 2012..Human influenza vaccines that elicit not only HA, but also NA immunity may provide enhanced protection against the emergence of seasonal and pandemic viruses...
The role of radiology in influenza: novel H1N1 and lessons learned from the 1918 pandemicDaniel J Mollura
Radiology and Imaging Sciences, National Institutes of Health, Clinical Center, 9000 Rockville Pike, Bethesda, MD 20892, USA
J Am Coll Radiol 7:690-7. 2010..The broad range of current imaging capabilities will make it possible to study influenza at the cellular level, in animal models, and in human clinical trials to elucidate the pathogenesis of severe illness and improve clinical outcomes...
A hexavalent human rotavirus-bovine rotavirus (UK) reassortant vaccine designed for use in developing countries and delivered in a schedule with the potential to eliminate the risk of intussusceptionAlbert Z Kapikian
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
J Infect Dis 192:S22-9. 2005..e., ages 3-4 months through age 9 months). In this way, there may be the potential to eliminate or at least significantly decrease the risk of intussusception associated with rotavirus vaccination...
Reappraisal of the association of intussusception with the licensed live rotavirus vaccine challenges initial conclusionsBrian R Murphy
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
J Infect Dis 187:1301-8. 2003
At the deathbed of consumptive artDavid M Morens
NIH, NIAID, Bethesda, MD 20892-7630, USA
Emerg Infect Dis 8:1353-8. 2002
Epidemic anthrax in the eighteenth century, the AmericasDavid M Morens
National Institutes of Health, Bethesda, Maryland, USA
Emerg Infect Dis 8:1160-2. 2002..Historical information may not only provide important clues about epidemic development but may also raise awareness about bioterrorism potential...
Dengue research opportunities in the AmericasCatherine A Laughlin
Virology Branch, Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892 6603, USA
J Infect Dis 206:1121-7. 2012..Although dengue is a major global tropical pathogen, epidemiologic and disease control considerations in this article emphasize dengue in the Americas...
Engineering H5N1 avian influenza viruses to study human adaptationDavid M Morens
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
Nature 486:335-40. 2012....
Pandemic influenza's 500th anniversaryDavid M Morens
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
Clin Infect Dis 51:1442-4. 2010..It seems likely that, in the foreseeable future, we may be able to greatly reduce the burden of influenza pandemics with improved vaccines and other scientific and public health approaches...
The 1918 influenza pandemic: insights for the 21st centuryDavid M Morens
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
J Infect Dis 195:1018-28. 2007....
Pandemic and seasonal influenza: therapeutic challengesMatthew J Memoli
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
Drug Discov Today 13:590-5. 2008....
The pathology of influenza virus infectionsJeffery K Taubenberger
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
Annu Rev Pathol 3:499-522. 2008....
The wages of original antigenic sinDavid M Morens
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
Emerg Infect Dis 16:1023-4. 2010
The challenge of emerging and re-emerging infectious diseasesDavid M Morens
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892-2520, USA
Nature 430:242-9. 2004..Studies of these emerging infections reveal the evolutionary properties of pathogenic microorganisms and the dynamic relationships between microorganisms, their hosts and the environment...
Fatal 1918 pneumonia case complicated by erythrocyte sicklingZong Mei Sheng
National Institutes of Health, Bethesda, Maryland, USA
Emerg Infect Dis 16:2000-1. 2010..The inheritance pattern of sickle cell anemia was determined in 1949; in 1957, Ingram identified the single amino acid change in hemoglobin S (4)...
Influenza and the origins of The Philips Collection, Washington, DCDavid M Morens
National Institutes of Health, Bethesda, MD, USA
Emerg Infect Dis 12:78-80. 2006
Influenza revisitedJeffery K Taubenberger
Armed Forces Institute of Pathology, Rockville, Maryland, USA
Emerg Infect Dis 12:1-2. 2006
Variant Creutzfeldt-Jakob disease and the acquired and transmissible spongiform encephalopathiesChristopher E Beisel
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-6603, USA
Clin Infect Dis 38:697-704. 2004....
1918 Influenza: the mother of all pandemicsJeffery K Taubenberger
Armed Forces Institute of Pathology, Rockville, Maryland 20850 3125, USA
Emerg Infect Dis 12:15-22. 2006..But, the viral genome alone is unlikely to provide answers to some critical questions. Understanding the 1918 pandemic and its implications for future pandemics requires careful experimentation and in-depth historical analysis...
Ecological studies, rotavirus vaccination, and intussusceptionLone Simonsen
Lancet 359:1066-7; author reply 1066. 2002
