Robert J Morell

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Characterization of a new full length TMPRSS3 isoform and identification of mutant alleles responsible for nonsyndromic recessive deafness in Newfoundland and Pakistan
    Zubair M Ahmed
    Section on Human Genetics, Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, MD, USA
    BMC Med Genet 5:24. 2004
  2. ncbi request reprint A twin study of auditory processing indicates that dichotic listening ability is a strongly heritable trait
    Robert J Morell
    Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, 5 Research Court, Rockville, MD 20850, USA
    Hum Genet 122:103-11. 2007
  3. ncbi request reprint Modification of human hearing loss by plasma-membrane calcium pump PMCA2
    Julie M Schultz
    Section on Human Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, MD 20850, USA
    N Engl J Med 352:1557-64. 2005
  4. pmc Targeted capture and next-generation sequencing identifies C9orf75, encoding taperin, as the mutated gene in nonsyndromic deafness DFNB79
    Atteeq Ur Rehman
    Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, MD 20850, USA
    Am J Hum Genet 86:378-88. 2010
  5. ncbi request reprint Clinical presentation of DFNB12 and Usher syndrome type 1D
    Julie M Bork
    Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, MD, USA
    Adv Otorhinolaryngol 61:145-52. 2002
  6. pmc Mutations of MYO6 are associated with recessive deafness, DFNB37
    Zubair M Ahmed
    Section on Human Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, MD 20850, USA
    Am J Hum Genet 72:1315-22. 2003
  7. pmc Mutations in TRIOBP, which encodes a putative cytoskeletal-organizing protein, are associated with nonsyndromic recessive deafness
    Saima Riazuddin
    Section on Human Genetics, Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health NIH, Rockville, MD 20850, USA
    Am J Hum Genet 78:137-43. 2006
  8. pmc Mutations in a novel gene, TMIE, are associated with hearing loss linked to the DFNB6 locus
    Sadaf Naz
    Section on Human Genetics, Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, MD, 20850, USA
    Am J Hum Genet 71:632-6. 2002
  9. ncbi request reprint Spatiotemporal pattern and isoforms of cadherin 23 in wild type and waltzer mice during inner ear hair cell development
    Ayala Lagziel
    Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, MD 20850, USA
    Dev Biol 280:295-306. 2005
  10. ncbi request reprint Mutational spectrum of MYO15A: the large N-terminal extension of myosin XVA is required for hearing
    Nevra Nal
    Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville 20850, Maryland, USA
    Hum Mutat 28:1014-9. 2007

Collaborators

  • Julie M Bork
  • Thomas B Friedman
  • Zubair M Ahmed
  • Saidi A Mohiddin
  • Rob W J Collin
  • Uwe Wolfrum
  • Hannie Kremer
  • H Snieder
  • A L Gropman
  • S M Leal
  • Richard J Smith
  • Mounira Hmani-Aifa
  • Ersan Kalay
  • Saima Riazuddin
  • Sheikh Riazuddin
  • Ayala Lagziel
  • Julie M Schultz
  • Shaheen N Khan
  • Manju Ghosh
  • Madhulika Kabra
  • Edward R Wilcox
  • Atteeq Ur Rehman
  • Sadaf Naz
  • Andrew J Griffith
  • Inna A Belyantseva
  • Nevra Nal
  • Anne C Madeo
  • Linda M Peters
  • Mohsin Shahzad
  • Shahid Y Khan
  • Erich T Boger
  • Glenn Merlino
  • Matthew F Starost
  • Ali M Waryah
  • Muhammad J Hassan
  • Nora Overlack
  • Dhananjay Chhatre
  • Ghazanfar Ali
  • Stephanie Buckley
  • Kwanghyuk Lee
  • Barbara Ploplis
  • Muhammad Ansar
  • Wasim Ahmad
  • Steven L Bernstein
  • David Velasquez
  • Parna Chattaraj
  • Oktay Dinc
  • Engin Erkal
  • Saba Tasneem
  • Tayyab Husnain
  • Guven Luleci
  • Erich Boger
  • Ali Muhammad Waryah
  • Ozgul M Alper
  • Quratul Ain
  • Anthony Antonellis
  • Kyle Caution
  • William J Pavan
  • Kevin Chen
  • Ahmad U Zafar
  • Sabiha Nazli
  • Penelope L Friedman
  • Eric D Green
  • Adelaida G Filoteo
  • Alan R Penheiter
  • Ariel J Caride
  • Lameh Fananapazir
  • Yandan Yang
  • John T Penniston
  • Arabandi Ramesh
  • Theresa B San Agustin
  • Kenneth M Grundfast
  • Kristina L Mitchem
  • David C Kohrman
  • Dilip Deshmukh
  • David W Anderson
  • Srikumari Srisailpathy
  • Chantal M Giguere

Detail Information

Publications14

  1. pmc Characterization of a new full length TMPRSS3 isoform and identification of mutant alleles responsible for nonsyndromic recessive deafness in Newfoundland and Pakistan
    Zubair M Ahmed
    Section on Human Genetics, Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, MD, USA
    BMC Med Genet 5:24. 2004
    ....
  2. ncbi request reprint A twin study of auditory processing indicates that dichotic listening ability is a strongly heritable trait
    Robert J Morell
    Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, 5 Research Court, Rockville, MD 20850, USA
    Hum Genet 122:103-11. 2007
    ..These findings should help illuminate the etiology of APDs, and help to clarify the relationships between auditory processing abilities and learning/language disorders associated with APDs...
  3. ncbi request reprint Modification of human hearing loss by plasma-membrane calcium pump PMCA2
    Julie M Schultz
    Section on Human Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, MD 20850, USA
    N Engl J Med 352:1557-64. 2005
    ....
  4. pmc Targeted capture and next-generation sequencing identifies C9orf75, encoding taperin, as the mutated gene in nonsyndromic deafness DFNB79
    Atteeq Ur Rehman
    Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, MD 20850, USA
    Am J Hum Genet 86:378-88. 2010
    ..Although TPRN is expressed in many tissues, immunolocalization of the protein product in the mouse cochlea shows prominent expression in the taper region of hair cell stereocilia. Consequently, we named the protein taperin...
  5. ncbi request reprint Clinical presentation of DFNB12 and Usher syndrome type 1D
    Julie M Bork
    Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, MD, USA
    Adv Otorhinolaryngol 61:145-52. 2002
  6. pmc Mutations of MYO6 are associated with recessive deafness, DFNB37
    Zubair M Ahmed
    Section on Human Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, MD 20850, USA
    Am J Hum Genet 72:1315-22. 2003
    ....
  7. pmc Mutations in TRIOBP, which encodes a putative cytoskeletal-organizing protein, are associated with nonsyndromic recessive deafness
    Saima Riazuddin
    Section on Human Genetics, Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health NIH, Rockville, MD 20850, USA
    Am J Hum Genet 78:137-43. 2006
    ..Genetic heterogeneity at this locus is suggested by three additional families that show significant evidence of linkage of deafness to markers on chromosome 22q13 but that apparently have no mutations in the TRIOBP gene...
  8. pmc Mutations in a novel gene, TMIE, are associated with hearing loss linked to the DFNB6 locus
    Sadaf Naz
    Section on Human Genetics, Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, MD, 20850, USA
    Am J Hum Genet 71:632-6. 2002
    ..TMIE encodes a protein with 156 amino acids and exhibits no significant nucleotide or deduced amino acid sequence similarity to any other gene...
  9. ncbi request reprint Spatiotemporal pattern and isoforms of cadherin 23 in wild type and waltzer mice during inner ear hair cell development
    Ayala Lagziel
    Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, MD 20850, USA
    Dev Biol 280:295-306. 2005
    ..Our results suggest that Cdh23 participation in stereocilia links may be restricted to developing hair bundles...
  10. ncbi request reprint Mutational spectrum of MYO15A: the large N-terminal extension of myosin XVA is required for hearing
    Nevra Nal
    Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville 20850, Maryland, USA
    Hum Mutat 28:1014-9. 2007
    ..These data demonstrate that isoform 1, containing the large N-terminal extension, is also necessary for normal hearing...
  11. ncbi request reprint Mutation of a transcription factor, TFCP2L3, causes progressive autosomal dominant hearing loss, DFNA28
    Linda M Peters
    Section on Human Genetics, Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, MD 20850, USA
    Hum Mol Genet 11:2877-85. 2002
    ..Northern blot analyses and in situ hybridization studies show that mouse Tfcp2l3 is expressed in many epithelial tissues, including cells lining the cochlear duct, at embryonic day 18.5 and postnatal day 5...
  12. pmc Mutations of LRTOMT, a fusion gene with alternative reading frames, cause nonsyndromic deafness in humans
    Zubair M Ahmed
    Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, Rockville, Maryland 20850, USA
    Nat Genet 40:1335-40. 2008
    ..We provide evidence that in the primate lineage LRTOMT evolved from the fusion of two neighboring ancestral genes, which exist as separate genes (Lrrc51 and Tomt) in rodents...
  13. pmc Noncoding mutations of HGF are associated with nonsyndromic hearing loss, DFNB39
    Julie M Schultz
    Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, MD 20850, USA
    Am J Hum Genet 85:25-39. 2009
    ..Overexpression of HGF is associated with progressive degeneration of outer hair cells in the cochlea, whereas cochlear deletion of Hgf is associated with more general dysplasia...
  14. pmc Expression of cadherin 23 isoforms is not conserved: implications for a mouse model of Usher syndrome type 1D
    Ayala Lagziel
    Section on Human Genetics, Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, MD 20850, USA
    Mol Vis 15:1843-57. 2009
    ....