Research Topics
Genomes and GenesSpecies | Steven C MooreSummaryAffiliation: National Institutes of Health Country: USA Publications
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Publications
Leisure time physical activity of moderate to vigorous intensity and mortality: a large pooled cohort analysisSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
PLoS Med 9:e1001335. 2012..Our objective was to determine the years of life gained after age 40 associated with various levels of physical activity, both overall and according to body mass index (BMI) groups, in a large pooled analysis...
Common genetic variants and central adiposity among Asian-IndiansSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, USA
Obesity (Silver Spring) 20:1902-8. 2012....
Height, body mass index, and physical activity in relation to glioma riskSteven C Moore
Nutritional Epidemiology Branch and Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, NIH, Rockville, Maryland, USA
Cancer Res 69:8349-55. 2009..Adult height, BMI during adolescence, and physical activity during adolescence were each associated with glioma risk, supporting a role for early-life energy balance in glioma carcinogenesis...
Physical activity, sedentary behaviours, and the prevention of endometrial cancerS C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Bethesda, MD 20892, USA
Br J Cancer 103:933-8. 2010..Taken together with the established biological plausibility of this relation, the totality of evidence now convincingly indicates that physical activity prevents or reduces risk of endometrial cancer...
Age-specific physical activity and prostate cancer risk among white men and black menSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
Cancer 115:5060-70. 2009..The authors investigated physical activity, including activity during different age periods and of various intensities, in relation to prostate cancer incidence among white men and black men...
Adipokine genes and prostate cancer riskSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Int J Cancer 124:869-76. 2009..05). Polymorphisms in the IL6, LEPR, TNF and ADIPOQ genes were not associated with prostate cancer. Allelic variants in the LEP gene are related to prostate cancer risk, supporting a role for leptin in prostate carcinogenesis...
Physical activity in relation to total, advanced, and fatal prostate cancerSteven C Moore
Division of Cancer Epidemiology, National Cancer Institute, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 17:2458-66. 2008..96; 95% CI, 0.67-1.36; P(trend) = 0.99). Neither vigorous exercise at baseline nor exercise during adolescence was related to risk of total, advanced, or fatal prostate cancer in this large prospective cohort...
Insulin resistance-related gene polymorphisms and risk of prostate cancerSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland 20892, USA
Cancer Epidemiol Biomarkers Prev 16:1315-7. 2007
Past body mass index and risk of mortality among womenS C Moore
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, MD 20892, USA
Int J Obes (Lond) 32:730-9. 2008..Analysis of BMI from an earlier time period may minimize reverse causation without requiring exclusion of participants based on disease or smoking history...
Physical activity during adulthood and adolescence in relation to renal cell cancerSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
Am J Epidemiol 168:149-57. 2008..82 (95% CI: 0.68, 1.00; p(trend) = 0.05) for activity during adolescence. The authors conclude that increased physical activity, including activity during adolescence, is associated with reduced risk of renal cell cancer...
Prospective study of physical activity and risk of postmenopausal breast cancerMichael F Leitzmann
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Breast Cancer Res 10:R92. 2008..To prospectively examine the relation of total, vigorous and non-vigorous physical activity to postmenopausal breast cancer risk...
Body size and renal cell cancer incidence in a large US cohort studyKenneth F Adams
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
Am J Epidemiol 168:268-77. 2008..Waist-to hip ratio was positively associated with RCC in women and with height at age 18 years in both men and women...
Beyond recreational physical activity: examining occupational and household activity, transportation activity, and sedentary behavior in relation to postmenopausal breast cancer riskStephanie M George
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
Am J Public Health 100:2288-95. 2010..We prospectively examined nonrecreational physical activity and sedentary behavior in relation to breast cancer risk among 97 039 postmenopausal women in the National Institutes of Health-AARP Diet and Health Study...
Intensity and timing of physical activity in relation to postmenopausal breast cancer risk: the prospective NIH-AARP diet and health studyTricia M Peters
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Blvd, Bethesda, MD, USA
BMC Cancer 9:349. 2009..Despite strong evidence of an inverse association of physical activity with postmenopausal breast cancer risk, whether a certain intensity or time of life of physical activity is most effective for lowering breast cancer risk is not known...
Body mass index and risk of ovarian cancerMichael F Leitzmann
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
Cancer 115:812-22. 2009..However, to the authors' knowledge, data addressing whether the relation between BMI and ovarian cancer differs by MHT use are very sparse...
Amount of time spent in sedentary behaviors and cause-specific mortality in US adultsCharles E Matthews
Nutritional Epidemiology Branch, National Cancer Institute, Rockville, MD, USA
Am J Clin Nutr 95:437-45. 2012..Sedentary behaviors predominate modern life, yet we do not fully understand the adverse effects of these behaviors on mortality after considering the benefits of moderate-vigorous physical activity (MVPA)...
Physical activity and postmenopausal breast cancer risk in the NIH-AARP diet and health studyTricia M Peters
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, MSC 7232, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 18:289-96. 2009..Although physical activity has been associated with reduced breast cancer risk, whether this association varies across breast cancer subtypes or is modified by reproductive and lifestyle factors is unclear...
Diabetes and thyroid cancer risk in the National Institutes of Health-AARP Diet and Health StudyBriseis Aschebrook-Kilfoy
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20892, USA
Thyroid 21:957-63. 2011....
Waist circumference as compared with body-mass index in predicting mortality from specific causesMichael F Leitzmann
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, U S Department of Health and Human Services, Bethesda, Maryland, United States of America
PLoS ONE 6:e18582. 2011..Whether waist circumference provides clinically meaningful information not delivered by body-mass index regarding prediction of cause-specific death is uncertain...
Body-mass index and mortality among 1.46 million white adultsAmy Berrington de Gonzalez
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
N Engl J Med 363:2211-9. 2010....
Body mass index, physical activity, and bladder cancer in a large prospective studyCorinna Koebnick
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 17:1214-21. 2008..358), respectively. In conclusion, these findings provide support for a modest adverse effect of adiposity on risk for bladder cancer. In contrast, our results do not suggest a relation between physical activity and bladder cancer...
Validity of a physical activity questionnaire in ShanghaiTricia M Peters
National Cancer Institute, Division of Cancer Epidemiology and Genetics, Bethesda, MD, USA
Med Sci Sports Exerc 42:2222-30. 2010..Because available PAQ may not capture the full range of PA in which urban Chinese adults engage, a PAQ was developed for this purpose. We examined the validity of this PAQ and the 1-yr stability of PA in 545 urban Shanghai adults...
Accelerometer-measured physical activity in Chinese adultsTricia M Peters
National Cancer Institute, Bethesda, Maryland, USA
Am J Prev Med 38:583-91. 2010..Following adoption of a Western lifestyle, China is experiencing a decline in physical activity levels, which is projected to contribute to future increases in the burden of chronic diseases...
Nonsteroidal anti-inflammatory drugs and glioma in the NIH-AARP Diet and Health Study cohortSarah E Daugherty
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
Cancer Prev Res (Phila) 4:2027-34. 2011..90; 95% CI, 0.65-1.25 and HR for glioblastoma = 0.83; 95% CI, 0.56-1.20) as compared with no use. Our findings from this large prospective study do not support an inverse association between NSAIDs and risk of all glioma or glioblastoma...
Prospective study of body mass index, physical activity and thyroid cancerMichael F Leitzmann
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health DHHS, Bethesda, MD 20892, USA
Int J Cancer 126:2947-56. 2010..Based on only 15 cases, adiposity was unrelated to medullary thyroid cancers. Physical activity was unrelated to total thyroid cancer...
A prospective analysis of prolonged sitting time and risk of renal cell carcinoma among 300,000 older adultsStephanie M George
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
Ann Epidemiol 21:787-90. 2011..The authors prospectively examined the relationship of prolonged sitting and risk of RCC among 289,512 women and men in the National Institutes of Health-AARP Diet and Health Study...
Joint associations of adiposity and physical activity with mortality: the National Institutes of Health-AARP Diet and Health StudyAnnemarie Koster
Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland 20892, USA
Am J Epidemiol 169:1344-51. 2009..High physical activity attenuated but did not eliminate the increased mortality risk associated with obesity. Preventing weight gain and promoting physical activity in older persons may lower mortality risk...
A prospective study of physical activity and the risk of pancreatic cancer among women (United States)Brook A Calton
Division of Cancer Epidemiology and Genetics, NCI NIH, Rockville, MD, USA
BMC Cancer 8:63. 2008..Several epidemiologic studies have examined the association between physical activity and pancreatic cancer risk; however, the results of these studies are not consistent...
Postdiagnosis diet quality, the combination of diet quality and recreational physical activity, and prognosis after early-stage breast cancerStephanie M George
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Suite 320, MSC 7232, Rockville, MD 20852, USA
Cancer Causes Control 22:589-98. 2011..To investigate, among women with breast cancer, how postdiagnosis diet quality and the combination of diet quality and recreational physical activity are associated with prognosis...
Prospective study of physical activity and the risk of ovarian cancerMichael F Leitzmann
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, Rockville, MD 20892, USA
Cancer Causes Control 20:765-73. 2009..Available studies on physical activity and ovarian cancer have produced inconsistent findings, with some previous studies reporting a positive association between vigorous physical activity and ovarian cancer risk...
Metabolomics in epidemiology: sources of variability in metabolite measurements and implicationsJoshua N Sampson
Corresponding Author Joshua N Sampson, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852
Cancer Epidemiol Biomarkers Prev 22:631-40. 2013..Here, the authors assess the variability of a large subset of metabolites and evaluate the implications for epidemiologic studies...
Body mass index and mortality in non-Hispanic black adults in the NIH-AARP Diet and Health StudyYikyung Park
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, United States of America
PLoS ONE 7:e50091. 2012..Although the prevalence of obesity (body mass index, kg/m(2), BMI ≥30) is higher in non-Hispanic blacks than in non-Hispanic whites, the relation of BMI to total mortality in non-Hispanic blacks is not well defined...
Improving self-reports of active and sedentary behaviors in large epidemiologic studiesCharles E Matthews
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7335, USA
Exerc Sport Sci Rev 40:118-26. 2012....
Invited commentary: circulating inflammation markers and cancer risk--implications for epidemiologic studiesAnil K Chaturvedi
Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 7072, Rockville, MD 20852, USA
Am J Epidemiol 177:14-9. 2013..Given that many large prospective cohort studies have already collected and banked serum/plasma samples, rapid gains in our understanding of chronic inflammation and its role in cancer etiology are possible...
Height and risk of prostate cancer in the prostate, lung, colorectal, and ovarian cancer screening trialJ Ahn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20852, USA
Br J Cancer 101:522-5. 2009..The relationship between prostate cancer and height is uncertain...
Healthy lifestyle and the risk of stroke in womenTobias Kurth
Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
Arch Intern Med 166:1403-9. 2006..Healthy lifestyle has been associated with decreased risk of coronary heart disease. In contrast, little is known about its association with stroke risk...
