Sharon P Moore

Summary

Affiliation: National Cancer Institute
Country: USA

Publications

  1. ncbi request reprint Analysis of a Ty1-less variant of Saccharomyces paradoxus: the gain and loss of Ty1 elements
    Sharon P Moore
    Gene Regulation and Chromosome Biology Laboratory, National Cancer Institute, PO Box B, Frederick, MD 21702 1201, USA
    Yeast 21:649-60. 2004
  2. pmc Functional analysis of N-terminal residues of ty1 integrase
    Sharon P Moore
    Gene Regulation and Chromosome Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, USA
    J Virol 83:9502-11. 2009
  3. pmc Retrotransposon suicide: formation of Ty1 circles and autointegration via a central DNA flap
    David J Garfinkel
    National Cancer Institute, P O Box B, Frederick, MD 21702 1201, USA
    J Virol 80:11920-34. 2006
  4. pmc Ty1 copy number dynamics in Saccharomyces
    David J Garfinkel
    Gene Regulation and Chromosome Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21701 1201, USA
    Genetics 169:1845-57. 2005

Detail Information

Publications4

  1. ncbi request reprint Analysis of a Ty1-less variant of Saccharomyces paradoxus: the gain and loss of Ty1 elements
    Sharon P Moore
    Gene Regulation and Chromosome Biology Laboratory, National Cancer Institute, PO Box B, Frederick, MD 21702 1201, USA
    Yeast 21:649-60. 2004
    ..The results indicate that Ty1 retrotransposition occurs at a much higher rate than elimination, suggesting that copy-number-dependent co-factors or environmental conditions contribute to the loss of Ty elements in this genome...
  2. pmc Functional analysis of N-terminal residues of ty1 integrase
    Sharon P Moore
    Gene Regulation and Chromosome Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, USA
    J Virol 83:9502-11. 2009
    ..Our results suggest that the histidine/cysteine residues are important for steps in transposition prior to integration, while the hydrophobic residues function in IN multimerization...
  3. pmc Retrotransposon suicide: formation of Ty1 circles and autointegration via a central DNA flap
    David J Garfinkel
    National Cancer Institute, P O Box B, Frederick, MD 21702 1201, USA
    J Virol 80:11920-34. 2006
    ..These results suggest that Ty1-specific mechanisms minimize copy number and raise the possibility that special DNA structures are a targeting determinant...
  4. pmc Ty1 copy number dynamics in Saccharomyces
    David J Garfinkel
    Gene Regulation and Chromosome Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, Maryland 21701 1201, USA
    Genetics 169:1845-57. 2005
    ..Ty1 gain/loss ratios obtained under different conditions suggest that copy number oscillates over time by altering the rate of retrotransposition, resulting in the diverse copy numbers observed in Saccharomyces...