L E Moore

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Improved identification of von Hippel-Lindau gene alterations in clear cell renal tumors
    Michael L Nickerson
    Transgenomic, Gaithersburg, Maryland, USA
    Clin Cancer Res 14:4726-34. 2008
  2. doi request reprint Occupational trichloroethylene exposure and kidney cancer risk: a meta-analysis
    Sara Karami
    National Cancer Institute, Division of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch, 6120 Executive Blvd, EPS 8102, Rockville, MD 20852, USA
    Occup Environ Med 69:858-67. 2012
  3. pmc Cell-cycle control in urothelial carcinoma: large-scale tissue array analysis of tumor tissue from Maine and Vermont
    Petra Lenz
    Division of Cancer Epidemiology and Genetics, Science Applications International Corporation Frederick, Inc, National Cancer Institute Frederick, Frederick, MD, USA
    Cancer Epidemiol Biomarkers Prev 21:1555-64. 2012
  4. pmc Correlation of LINE-1 methylation levels in patient-matched buffy coat, serum, buccal cell, and bladder tumor tissue DNA samples
    Dana Van Bemmel
    Occupational and Environmental Epidemiology Branch, Epidemiology and Biostatistics Program, National Cancer Institute, NIH, DHHS, Bethesda, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 21:1143-8. 2012
  5. ncbi request reprint Identification of biomarkers of arsenic exposure and metabolism in urine using SELDI technology
    L E Moore
    Occupational and Environmental Epidemiology Branch, National Cancer Institute, Rockville, MD 20892, USA
    J Biochem Mol Toxicol 19:176. 2005
  6. ncbi request reprint Evaluation of apolipoprotein A1 and posttranslationally modified forms of transthyretin as biomarkers for ovarian cancer detection in an independent study population
    Lee E Moore
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 6120 Executive Boulevard, EPS 8118, Bethesda, MD 20852 7240, USA
    Cancer Epidemiol Biomarkers Prev 15:1641-6. 2006
  7. ncbi request reprint Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer
    Lee E Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
    Int J Cancer 120:2452-8. 2007
  8. pmc Genomic DNA hypomethylation as a biomarker for bladder cancer susceptibility in the Spanish Bladder Cancer Study: a case-control study
    Lee E Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, MD, USA
    Lancet Oncol 9:359-66. 2008
  9. ncbi request reprint Whole genome amplification of buccal cytobrush DNA collected for molecular epidemiology studies
    L E Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20852 7240, USA
    Biomarkers 12:303-12. 2007
  10. ncbi request reprint Glutathione S-transferase polymorphisms, cruciferous vegetable intake and cancer risk in the Central and Eastern European Kidney Cancer Study
    L E Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Carcinogenesis 28:1960-4. 2007

Detail Information

Publications52

  1. pmc Improved identification of von Hippel-Lindau gene alterations in clear cell renal tumors
    Michael L Nickerson
    Transgenomic, Gaithersburg, Maryland, USA
    Clin Cancer Res 14:4726-34. 2008
    ..Identify relationships between the prevalence of VHL gene alterations and alteration subtypes with patient and tumor characteristics...
  2. doi request reprint Occupational trichloroethylene exposure and kidney cancer risk: a meta-analysis
    Sara Karami
    National Cancer Institute, Division of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch, 6120 Executive Blvd, EPS 8102, Rockville, MD 20852, USA
    Occup Environ Med 69:858-67. 2012
    ..We updated meta-analyses of published case-control and cohort studies exploring occupational TCE exposure and kidney cancer risk, incorporating new analytical results from three recently published cohort studies and a case-control study...
  3. pmc Cell-cycle control in urothelial carcinoma: large-scale tissue array analysis of tumor tissue from Maine and Vermont
    Petra Lenz
    Division of Cancer Epidemiology and Genetics, Science Applications International Corporation Frederick, Inc, National Cancer Institute Frederick, Frederick, MD, USA
    Cancer Epidemiol Biomarkers Prev 21:1555-64. 2012
    ..Cell-cycle proteins are important predictive markers in urothelial carcinoma but may also exhibit exposure-specific heterogeneity...
  4. pmc Correlation of LINE-1 methylation levels in patient-matched buffy coat, serum, buccal cell, and bladder tumor tissue DNA samples
    Dana Van Bemmel
    Occupational and Environmental Epidemiology Branch, Epidemiology and Biostatistics Program, National Cancer Institute, NIH, DHHS, Bethesda, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 21:1143-8. 2012
    ..To date, most studies have used genomic DNA isolated from blood or urine as a surrogate marker of global DNA methylation levels in bladder tumor tissue...
  5. ncbi request reprint Identification of biomarkers of arsenic exposure and metabolism in urine using SELDI technology
    L E Moore
    Occupational and Environmental Epidemiology Branch, National Cancer Institute, Rockville, MD 20892, USA
    J Biochem Mol Toxicol 19:176. 2005
  6. ncbi request reprint Evaluation of apolipoprotein A1 and posttranslationally modified forms of transthyretin as biomarkers for ovarian cancer detection in an independent study population
    Lee E Moore
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 6120 Executive Boulevard, EPS 8118, Bethesda, MD 20852 7240, USA
    Cancer Epidemiol Biomarkers Prev 15:1641-6. 2006
    ..A previous study by Zhang et al. reported identification and validation of three biomarkers using proteomic profiling that together improved early-stage ovarian cancer detection...
  7. ncbi request reprint Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer
    Lee E Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
    Int J Cancer 120:2452-8. 2007
    ..Additional work is needed to comprehensively evaluate genomic variation in CTH and related genes in the trans-sulfuration pathway and bladder cancer risk...
  8. pmc Genomic DNA hypomethylation as a biomarker for bladder cancer susceptibility in the Spanish Bladder Cancer Study: a case-control study
    Lee E Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, MD, USA
    Lancet Oncol 9:359-66. 2008
    ..DNA hypomethylation has been suggested to cause genomic instability and increase cancer risk. We aimed to test the hypothesis that DNA hypomethylation is associated with increased risk of bladder cancer...
  9. ncbi request reprint Whole genome amplification of buccal cytobrush DNA collected for molecular epidemiology studies
    L E Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20852 7240, USA
    Biomarkers 12:303-12. 2007
    ..To reduce genotype misclassification when cytobrush wgaDNA is used, inclusion of paired gDNA/wgaDNA and/or duplicate wgaDNA samples is critical to monitor data quality...
  10. ncbi request reprint Glutathione S-transferase polymorphisms, cruciferous vegetable intake and cancer risk in the Central and Eastern European Kidney Cancer Study
    L E Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Carcinogenesis 28:1960-4. 2007
    ..49; 95% CI: 1.08-5.77; P-interaction = 0.05). These data provide additional evidence for the role of cruciferous vegetables in cancer prevention among individuals with common, functional genetic polymorphisms...
  11. ncbi request reprint Folate metabolism genes, vegetable intake and renal cancer risk in central Europe
    Lee E Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
    Int J Cancer 122:1710-5. 2008
    ..04 for all). In summary, these findings suggest that common variation in MTHFR and TYMS genes may be associated with RCC risk, particularly when vegetable intake is low...
  12. pmc GSTM1 null and NAT2 slow acetylation genotypes, smoking intensity and bladder cancer risk: results from the New England bladder cancer study and NAT2 meta-analysis
    L E Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20852, USA
    Carcinogenesis 32:182-9. 2011
    ..Findings from this large USA population-based study provided evidence that the NAT2 slow acetylation genotype interacts with tobacco smoking as a function of exposure intensity...
  13. pmc Occupational trichloroethylene exposure and renal carcinoma risk: evidence of genetic susceptibility by reductive metabolism gene variants
    Lee E Moore
    Division of Cancer Epidemiology and Genetics, NIH, National Cancer Institute, NIH, Bethesda, Maryland 20852, USA
    Cancer Res 70:6527-36. 2010
    ....
  14. pmc Apolipoprotein E/C1 locus variants modify renal cell carcinoma risk
    Lee E Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20852, USA
    Cancer Res 69:8001-8. 2009
    ..In two large case-control studies, our findings further define a functional region of interest at the APOE locus that increases RCC susceptibility...
  15. pmc Proteomic biomarkers in combination with CA 125 for detection of epithelial ovarian cancer using prediagnostic serum samples from the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial
    Lee E Moore
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Cancer 118:91-100. 2012
    ..Several biomarkers were evaluated alone and in combination with CA 125 in prediagnostically collected sera from women in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial...
  16. pmc Von Hippel-Lindau (VHL) inactivation in sporadic clear cell renal cancer: associations with germline VHL polymorphisms and etiologic risk factors
    Lee E Moore
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Genet 7:e1002312. 2011
    ..A proportion of tumors from current smokers lacked VHL alterations and may represent a biologically distinct clinical entity from inactivated cases...
  17. ncbi request reprint GSTM1, GSTT1, and GSTP1 polymorphisms and risk of advanced colorectal adenoma
    Lee E Moore
    National Cancer Institute, 6120 Executive Boulevard, EPS 7034, Bethesda, MD 20892 7240, USA
    Cancer Epidemiol Biomarkers Prev 14:1823-7. 2005
    ..These findings only became apparent using a newly developed assay able to distinguish heterozygous from wild-type individuals. Our data provide evidence that phenotypic differences between these two groups exist...
  18. ncbi request reprint Childhood cancer incidence and arsenic exposure in drinking water in Nevada
    Lee E Moore
    School of Public Health University of California at Berkeley, Berkeley, California, USA
    Arch Environ Health 57:201-6. 2002
    ..Nonetheless, the results raise the possibility that there are increased risks for nonleukemic childhood cancers that require confirmation in other studies, particularly those in which higher exposures are addressed...
  19. ncbi request reprint Parental occupational exposures and Ewing's sarcoma
    Lee E Moore
    Division of Cancer Epidemiology and Genetics, NCI, NIH, DHHS, Bethesda, MD 20892 7249, USA
    Int J Cancer 114:472-8. 2005
    ....
  20. ncbi request reprint Lifestyle factors, exposures, genetic susceptibility, and renal cell cancer risk: a review
    Lee E Moore
    Occupational Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland, USA
    Cancer Invest 23:240-55. 2005
    ....
  21. ncbi request reprint Arsenic-related chromosomal alterations in bladder cancer
    Lee E Moore
    L E Moore, A H Smith, University of California at Berkeley School of Public Health, Berkeley, USA
    J Natl Cancer Inst 94:1688-96. 2002
    ..This study was designed to compare chromosomal alterations in bladder cancers of arsenic-exposed individuals to provide insight into the mechanism of how arsenic may induce or promote cancer...
  22. ncbi request reprint Epidemiologic considerations to assess altered DNA methylation from environmental exposures in cancer
    Lee E Moore
    Occupational Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Ann N Y Acad Sci 983:181-96. 2003
    ..Methods for incorporating markers of DNA methylation status into etiologic investigations of the impact of environmental exposures on disease (e.g., cancer) are discussed...
  23. pmc Renal cell carcinoma, occupational pesticide exposure and modification by glutathione S-transferase polymorphisms
    S Karami
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20852, USA
    Carcinogenesis 29:1567-71. 2008
    ..These findings further support the hypothesis that glutathione S-transferase polymorphisms can modify RCC risk associated with occupational pesticide exposure...
  24. pmc Occupational exposure to dusts and risk of renal cell carcinoma
    S Karami
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Occupational and Environmental Epidemiology Branch, 6120 Executive Boulevard, EPS 8121, Rockville, MD 20852, USA
    Br J Cancer 104:1797-803. 2011
    ..We investigated whether asbestos, as well as 20 other occupational dust exposures, were associated with RCC risk in a large European, multi-center, hospital-based renal case-control study...
  25. pmc Vitamin D receptor polymorphisms and renal cancer risk in Central and Eastern Europe
    S Karami
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA karamis mail nih gov
    J Toxicol Environ Health A 71:367-72. 2008
    ..60; 95% CI: 0.33-1.1; P trend = 0.05). Genotype associations with these subgroups were not modified when dietary sources of vitamin D or calcium were considered. Additional studies of genetic variation in the VDR gene are warranted...
  26. pmc Vitamin d pathway genes, diet, and risk of renal cell carcinoma
    S Karami
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
    Int J Endocrinol 2010:879362. 2010
    ..Results suggest that variants in the RXRA gene modified the associations observed between RCC risk and calcium and vitamin D intake...
  27. ncbi request reprint Genetic polymorphisms in MTHFR 677 and 1298, GSTM1 and T1, and metabolism of arsenic
    Craig Steinmaus
    Arsenic Health Effects Research Program, School of Public Health, University of California, Berkeley, California, USA
    J Toxicol Environ Health A 70:159-70. 2007
    ..Overall, this study provides evidence that MTHFR and GSTM1 are involved in arsenic metabolism in humans, and polymorphisms in the genes that encode these enzymes may play a role in susceptibility to arsenic-induced cancer...
  28. ncbi request reprint Investigation of genetic polymorphisms and smoking in a bladder cancer case-control study in Argentina
    Lee E Moore
    School of Public Health, Arsenic Health Effects Research Program, University of California, 140 Warren Hall, Berkeley, CA 94720 7360, USA
    Cancer Lett 211:199-207. 2004
    ..Having both null polymorphisms conferred the highest risks. The MTHFR 677 CT and TT polymorphisms appeared protective against bladder cancer...
  29. ncbi request reprint Case-control study of bladder cancer and exposure to arsenic in Argentina
    Michael N Bates
    Arsenic Health Effects Research Group, School of Public Health, University of California, Berkeley, CA 94720 7360, USA
    Am J Epidemiol 159:381-9. 2004
    ..This study suggests lower bladder cancer risks for arsenic than predicted from other studies but adds to evidence that the latency for arsenic-induced bladder cancers may be longer than previously thought...
  30. ncbi request reprint Quantitation of DNA in buccal cell samples collected in epidemiological studies
    M Garcia-Closas
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Biomarkers 11:472-9. 2006
    ....
  31. ncbi request reprint Simulation and parameter estimation study of a simple neuronal model of rhythm generation: role of NMDA and non-NMDA receptors
    J Tabak
    Equipe de Neurobiologie, CNRS URA 256, Universite de Rennes, France
    J Comput Neurosci 5:209-35. 1998
    ..1993), gives a better understanding of the parameter subspace describing network activity than a standard fit with a sensitivity analysis for an individual solution...
  32. ncbi request reprint Parameter estimation methods for single neuron models
    J Tabak
    Equipe de Neurobiologie, CNRS URA 256, Universite de Rennes 1
    J Comput Neurosci 9:215-36. 2000
    ..This analysis indicates how well a parameter is likely to be estimated and helps choose an optimal stimulation protocol. Finally, the tests suggest a strategy for fitting single-cell models using the two methods examined...
  33. pmc Occupational sunlight exposure and risk of renal cell carcinoma
    Sara Karami
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Cancer 116:2001-10. 2010
    ....
  34. pmc Simultaneous recovery of DNA and RNA from formalin-fixed paraffin-embedded tissue and application in epidemiologic studies
    Wen Yi Huang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 8110, MSC 7240, Bethesda, MD 20892 7240, USA
    Cancer Epidemiol Biomarkers Prev 19:973-7. 2010
    ..Here, we report the method that we used to simultaneously recover DNA and RNA from FFPE tissue specimens with appreciable quantity and quality and discuss briefly the application of tumor markers in epidemiologic studies...
  35. pmc Occupation and bladder cancer in a population-based case-control study in Northern New England
    Joanne S Colt
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 7240, USA
    Occup Environ Med 68:239-49. 2011
    ..We used data from a large, population-based case-control study in Maine, New Hampshire, and Vermont to examine relationships between occupation, industry and bladder cancer risk...
  36. pmc Renal cancer risk and occupational exposure to polycyclic aromatic hydrocarbons and plastics
    Sara Karami
    National Cancer Institute, Division of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch, 6120 Executive Blvd, EPS 8121, Rockville, MD 20852, USA
    J Occup Environ Med 53:218-23. 2011
    ..To investigate whether occupational exposure to polycyclic aromatic hydrocarbons and certain plastic monomers increased renal cell carcinoma (RCC) risk...
  37. pmc A framework for evaluating biomarkers for early detection: validation of biomarker panels for ovarian cancer
    Claire S Zhu
    Division of Cancer Prevention, National Cancer Institute, National Institute of Health, Bethesda, MD 20892 7346, USA
    Cancer Prev Res (Phila) 4:375-83. 2011
    ..Thus, biomarker panels discovered in diagnostic samples may not validate in prediagnostic samples; utilizing prediagnostic samples for discovery may be helpful in developing validated early detection panels...
  38. pmc An analysis of growth, differentiation and apoptosis genes with risk of renal cancer
    Linda M Dong
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America
    PLoS ONE 4:e4895. 2009
    ..In conclusion, our evaluation has identified common genetic variants in CASP1, CASP5, EGFR, and IGFBP3 that could be associated with renal cancer risk...
  39. pmc Variants in blood pressure genes and the risk of renal cell carcinoma
    Gabriella Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20852 4906, USA
    Carcinogenesis 31:614-20. 2010
    ..003). Our findings suggest that common genetic variants of AGT, particularly those in the promoter, increase RCC risk among subjects who are hypertensive or overweight...
  40. pmc Analysis of SNPs and haplotypes in vitamin D pathway genes and renal cancer risk
    Sara Karami
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health NIH, Department of Health and Human Services DHHS, Bethesda, Maryland, USA
    PLoS ONE 4:e7013. 2009
    ..This study comprehensively evaluated genetic variation across eight vitamin D pathway genes in relation to RCC risk. We found increased risk associated with VDR and RXRA. Replication studies are warranted to confirm these findings...
  41. ncbi request reprint Occupational exposures and salivary gland cancer mortality among African American and white workers in the United States
    Robin T Wilson
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, DHHS, Bethesda, Maryland 20892 7240, USA
    J Occup Environ Med 46:287-97. 2004
    ..0 or greater among African American women, although not statistically significant. These findings suggest occupational and demographic factors needing further investigation...
  42. pmc Respiratory cancer and inhaled inorganic arsenic in copper smelters workers: a linear relationship with cumulative exposure that increases with concentration
    Jay H Lubin
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Environ Health Perspect 116:1661-5. 2008
    ....
  43. ncbi request reprint Bladder cancer and mate consumption in Argentina: a case-control study
    Michael N Bates
    School of Public Health, University of California, Berkeley, CA 94720 7360, USA
    Cancer Lett 246:268-73. 2007
    ..77, 95% confidence interval: 1.17-12.1), but not in never-smokers. Mate cocido was not associated with bladder cancer. These results are consistent with a previous study in Uruguay...
  44. ncbi request reprint Arsenic methylation and bladder cancer risk in case-control studies in Argentina and the United States
    Craig Steinmaus
    Arsenic Health Effects Research Program, School of Public Health, University of California, Berkeley, CA 94720 7360, USA
    J Occup Environ Med 48:478-88. 2006
    ..We sought to assess whether the metabolism of arsenic impacts a person's susceptibility to bladder cancer...
  45. pmc Occupational exposure to formaldehyde, hematotoxicity, and leukemia-specific chromosome changes in cultured myeloid progenitor cells
    Luoping Zhang
    School of Public Health, University of California at Berkeley, Berkeley, California 94720, USA
    Cancer Epidemiol Biomarkers Prev 19:80-8. 2010
    ....
  46. pmc Decreased urinary beta-defensin-1 expression as a biomarker of response to arsenic
    Christine M Hegedus
    School of Public Health, University of California, Berkeley, California 94720 7356, USA
    Toxicol Sci 106:74-82. 2008
    ..Further studies are warranted to investigate the role of HBD-1 in As-related toxicity...
  47. pmc Common genetic variants in the 9p21 region and their associations with multiple tumours
    F Gu
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20852, USA
    Br J Cancer 108:1378-86. 2013
    ..The chromosome 9p21.3 region has been implicated in the pathogenesis of multiple cancers...
  48. ncbi request reprint P53 alterations in bladder tumors from arsenic and tobacco exposed patients
    Lee E Moore
    Arsenic Health Effects Research Program, School of Public Health, University of California, 140 Warren Hall 7360, Berkeley, CA 7360, USA
    Carcinogenesis 24:1785-91. 2003
    ..Arsenic exposure was not associated with an increased prevalence of p53 mutation or P53 immunopositivity and there was no evidence of interaction between arsenic and smoking with these outcome variables...
  49. pmc Global DNA hypomethylation is associated with high serum-persistent organic pollutants in Greenlandic Inuit
    Jennifer A Rusiecki
    Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
    Environ Health Perspect 116:1547-52. 2008
    ..DNA methylation, an epigenetic mechanism, has been associated with cancer initiation and progression. Greenlandic Inuit have some of the highest reported POP levels worldwide...
  50. ncbi request reprint Blood concentrations of methionine, selenium, beta-carotene, and other micronutrients in a case-control study of arsenic-induced skin lesions in West Bengal, India
    Joyce S Chung
    Arsenic Health Effects Research Program, School of Public Health, University of California, Berkeley, CA 94720, USA
    Environ Res 101:230-7. 2006
    ..The emphasis of interventions should be on reducing arsenic exposure...
  51. pmc Family correlations of arsenic methylation patterns in children and parents exposed to high concentrations of arsenic in drinking water
    Joyce S Chung
    School of Public Health, University of California, Berkeley, California 94720, USA
    Environ Health Perspect 110:729-33. 2002
    ..Larger studies with more extensive pedigrees will need to be conducted to confirm these findings...
  52. ncbi request reprint Measurement of urine pH for epidemiological studies on bladder cancer
    Juan Alguacil
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Eur J Epidemiol 22:91-8. 2007
    ....