Eric T Moolchan

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Addressing tobacco-related health disparities
    Eric T Moolchan
    National Institute on Drug Abuse, Baltimore, MD 21224, USA
    Addiction 102:30-42. 2007
  2. pmc Perception of smoking risks and motivation to quit among nontreatment-seeking smokers with and without schizophrenia
    Deanna L Kelly
    Maryland Psychiatric Research Center, University of Maryland, Baltimore School of Medicine, Box 21247, Baltimore, MD 21228, USA
    Schizophr Bull 38:543-51. 2012
  3. ncbi request reprint Dose-related enhancement of mood and cognition in smokers administered nicotine nasal spray
    Carol S Myers
    Clinical Pharmacology and Therapeutics Branch, National Institute on Drug Abuse, NIH Intramural Research Program, Baltimore, MD 21224, USA
    Neuropsychopharmacology 33:588-98. 2008
  4. ncbi request reprint Smoking rates and topography predict adolescent smoking cessation following treatment with nicotine replacement therapy
    Frederick H Franken
    Department of Health and Human Services, National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD 21224, USA
    Cancer Epidemiol Biomarkers Prev 15:154-7. 2006
  5. pmc Excretion of methamphetamine and amphetamine in human sweat following controlled oral methamphetamine administration
    Allan J Barnes
    Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Clin Chem 54:172-80. 2008
  6. pmc Promoting abstinence from cocaine and heroin with a methadone dose increase and a novel contingency
    David H Epstein
    Treatment Section, Clinical Pharmacology and Therapeutics Branch, Intramural Research Branch of the National Institute on Drug Abuse, 251 Bayview Blvd, Suite 200, Baltimore, MD 21224, USA
    Drug Alcohol Depend 101:92-100. 2009
  7. pmc Interest in marijuana treatment programs among teenage smokers and nonsmokers
    Amy J Sheer
    National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD 21224, USA
    J Subst Abuse Treat 37:421-5. 2009
  8. pmc Puffing behavior during the smoking of a single cigarette in tobacco-dependent adolescents
    Charles C Collins
    Nicotine Psychopharmacology Section, Intramural Research Program, National Institute on Drug Abuse, 251 Bayview Boulevard, Baltimore, MD 21224, USA
    Nicotine Tob Res 12:164-7. 2010
  9. doi request reprint Age at menarche and weight concerns in relation to smoking trajectory and dependence among adolescent girls enrolled in a smoking cessation trial
    Maria Jaszyna-Gasior
    National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Department of Health and Human Services, Biomedical Research Center, Baltimore, Maryland 21224, USA
    Addict Behav 34:92-5. 2009
  10. pmc Cannabinoid concentrations in hair from documented cannabis users
    Marilyn A Huestis
    Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, United States
    Forensic Sci Int 169:129-36. 2007

Collaborators

Detail Information

Publications78

  1. ncbi request reprint Addressing tobacco-related health disparities
    Eric T Moolchan
    National Institute on Drug Abuse, Baltimore, MD 21224, USA
    Addiction 102:30-42. 2007
    ..We will show the importance of an approach that integrates the human life-cycle (developmental) and tobacco addiction cycle (behavioral) for interventions that address group-specific vulnerabilities...
  2. pmc Perception of smoking risks and motivation to quit among nontreatment-seeking smokers with and without schizophrenia
    Deanna L Kelly
    Maryland Psychiatric Research Center, University of Maryland, Baltimore School of Medicine, Box 21247, Baltimore, MD 21228, USA
    Schizophr Bull 38:543-51. 2012
    ....
  3. ncbi request reprint Dose-related enhancement of mood and cognition in smokers administered nicotine nasal spray
    Carol S Myers
    Clinical Pharmacology and Therapeutics Branch, National Institute on Drug Abuse, NIH Intramural Research Program, Baltimore, MD 21224, USA
    Neuropsychopharmacology 33:588-98. 2008
    ..These results provide an unequivocal determination that nicotine enhanced attentional and computational abilities in nondeprived smokers and suggest these cognitive domains as substrates for novel therapeutic indications...
  4. ncbi request reprint Smoking rates and topography predict adolescent smoking cessation following treatment with nicotine replacement therapy
    Frederick H Franken
    Department of Health and Human Services, National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD 21224, USA
    Cancer Epidemiol Biomarkers Prev 15:154-7. 2006
    ..If confirmed in a larger sample, our findings suggest that puff topography, and possibly CPD, might predict cessation outcome better than Fagerström scores in adolescent smokers...
  5. pmc Excretion of methamphetamine and amphetamine in human sweat following controlled oral methamphetamine administration
    Allan J Barnes
    Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Clin Chem 54:172-80. 2008
    ..Understanding methamphetamine (MAMP) and amphetamine (AMP) excretion in sweat is important for interpreting sweat and hair testing results in judicial, workplace, and drug treatment settings...
  6. pmc Promoting abstinence from cocaine and heroin with a methadone dose increase and a novel contingency
    David H Epstein
    Treatment Section, Clinical Pharmacology and Therapeutics Branch, Intramural Research Branch of the National Institute on Drug Abuse, 251 Bayview Blvd, Suite 200, Baltimore, MD 21224, USA
    Drug Alcohol Depend 101:92-100. 2009
    ..For a split contingency to promote simultaneous abstinence from cocaine and heroin, a relatively high dose of methadone appears necessary but not sufficient; an increase in overall incentive amount may also be required...
  7. pmc Interest in marijuana treatment programs among teenage smokers and nonsmokers
    Amy J Sheer
    National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD 21224, USA
    J Subst Abuse Treat 37:421-5. 2009
    ..These findings suggest that most adolescent marijuana smokers endorse the need for and are willing to attend marijuana treatment programs...
  8. pmc Puffing behavior during the smoking of a single cigarette in tobacco-dependent adolescents
    Charles C Collins
    Nicotine Psychopharmacology Section, Intramural Research Program, National Institute on Drug Abuse, 251 Bayview Boulevard, Baltimore, MD 21224, USA
    Nicotine Tob Res 12:164-7. 2010
    ..The purpose of this study was to examine the pattern of puffing behavior during the smoking of a single cigarette in adolescents...
  9. doi request reprint Age at menarche and weight concerns in relation to smoking trajectory and dependence among adolescent girls enrolled in a smoking cessation trial
    Maria Jaszyna-Gasior
    National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Department of Health and Human Services, Biomedical Research Center, Baltimore, Maryland 21224, USA
    Addict Behav 34:92-5. 2009
    ..Findings support previous research showing that early maturation represents a risk factor for substance use. Further study in larger samples that include non-treatment-seeking adolescent female smokers is warranted...
  10. pmc Cannabinoid concentrations in hair from documented cannabis users
    Marilyn A Huestis
    Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, United States
    Forensic Sci Int 169:129-36. 2007
    ..01, Pearson's product moment correlation). Using an immunoassay cutoff concentration of 5 pg THC equiv./mg hair, 83% of specimens that screened positive were confirmed by GCMSMS at a cutoff concentration of 0.1 pg THCCOOH/mg hair...
  11. pmc Consistency of subjective responses to imagery-induced tobacco craving over multiple sessions
    Dustin C Lee
    Clinical Pharmacology and Therapeutics Branch, National Institute on Drug Abuse, Intramural Research Program, NIH, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Addict Behav 32:2130-9. 2007
    ..These results have practical implications for examining individual differences in sensitivity to smoking cues and for studies involving repeated measurement of elicited craving over time...
  12. ncbi request reprint Alcohol use and tobacco abstinence among adolescents in cessation treatment: preliminary findings
    Maria Jaszyna-Gasior
    National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Department of Health and Human Services, Baltimore, USA
    Addict Behav 32:617-21. 2007
    ..If confirmed in a larger group of adolescents, our findings suggest that youths attempting to quit smoking should abstain from alcohol...
  13. ncbi request reprint Opioid disposition in human sweat after controlled oral codeine administration
    Eugene W Schwilke
    Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, NIH, Baltimore, MD 21224, USA
    Clin Chem 52:1539-45. 2006
    ..Characterization of opioid excretion in sweat is important for accurate interpretation of sweat tests in drug treatment, criminal justice, and workplace drug testing programs...
  14. ncbi request reprint Adolescents with conduct disorder: early smoking and treatment requests
    Kara S Bagot
    The National Institute on Drug Abuse, Intramural Research Program, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Am J Addict 16:62-6. 2007
    ..These findings suggest that in addition to addressing disruptive behaviors, early prevention and access to interventions for tobacco use are needed for youths with CD...
  15. pmc A link between adolescent nicotine metabolism and smoking topography
    Eric T Moolchan
    National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, MD, USA
    Cancer Epidemiol Biomarkers Prev 18:1578-83. 2009
    ....
  16. ncbi request reprint Adolescent smokers screened for a nicotine replacement treatment trial: correlates of eligibility and enrollment
    Miqun L Robinson
    Clinical Pharmacology and Treatment Research Branch, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, U S Department of Health and Human Services, MD 21224, USA
    Nicotine Tob Res 8:447-54. 2006
    ..3%) enrolled. Results underscore the need for screening instruments that are measurement-invariant across ethnicities and gender, and for enrollment strategies that maximize inclusion of eligible participants...
  17. ncbi request reprint Adolescent nicotine metabolism: ethnoracial differences among dependent smokers
    Eric T Moolchan
    National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland 21224, USA
    Ethn Dis 16:239-43. 2006
    ..Our results underscore the need for measures independent of consumption for determining degree of nicotine dependence and treatment selection across ethnicities, even among youths...
  18. ncbi request reprint Reasons for wanting to quit: ethnic differences among cessation-seeking adolescent smokers
    Emily J Luther
    Teen Tobacco Addiction Research Clinic, Clinical Pharmacology and Therapeutics Research Branch, National Institute on Drug Abuse, Baltimore, Maryland, USA
    Ethn Dis 16:739-43. 2006
    ..Enhancing adolescent cessation requires an understanding of approaches that will motivate youths to quit smoking...
  19. ncbi request reprint Placebo cigarettes in a spaced smoking paradigm
    Nicole C Eid
    National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD, USA
    Pharmacol Biochem Behav 81:158-64. 2005
    ..However, the nicotine yield of the cigarette did not influence these patterns. It is concluded that acute tobacco cravings can be repeatedly diminished with cigarettes that do not deliver nicotine...
  20. ncbi request reprint Tobacco craving predicts lapse to smoking among adolescent smokers in cessation treatment
    Kara S Bagot
    National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD 21224, USA
    Nicotine Tob Res 9:647-52. 2007
    ..Thus monitoring and addressing craving appears useful to increase the success of adolescent smoking cessation...
  21. ncbi request reprint Progression to daily smoking: is there a gender difference among cessation treatment seekers?
    Elissa D Thorner
    Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD 21224, USA
    Subst Use Misuse 42:829-35. 2007
    ..Additional research is needed to explore the specific factors that differentially affect smoking trajectory in girls compared to boys...
  22. ncbi request reprint Smoking topography and trajectory of asthmatic adolescents requesting cessation treatment
    Darin M Zimmerman
    Teen Tobacco Addiction Treatment Research Clinic, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, U S Department of Health and Human Services, Baltimore, MD 21224, USA
    Prev Med 39:940-2. 2004
    ..Smoke exposure aggravates the clinical course of asthma, yet few reports have examined the association between asthma and smoking topography and trajectory...
  23. ncbi request reprint Ethnic differences among adolescents seeking smoking cessation treatment: a structural analysis of responses on the Fagerström Test for Nicotine Dependence
    Jennifer R Schroeder
    Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD 21224, USA
    Nicotine Tob Res 9:137-45. 2007
    ..However, MIMIC modeling indicated differential reporting for three out of six items, suggesting that the FTND may not measure nicotine dependence equivalently for White and African American youth...
  24. ncbi request reprint Recent marijuana blunt smoking impacts carbon monoxide as a measure of adolescent tobacco abstinence
    Eric T Moolchan
    Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland 21224, USA
    Subst Use Misuse 40:231-40. 2005
    ..013). Blunt occasions also tended to be associated with the more youth-appropriate cutoff CO > or = 6 ppm, compared to non-MJ occasions (p =0.054). Blunt smoking impacted the interpretation of measures of exhaled CO for tobacco cessation...
  25. ncbi request reprint Tobacco smoking trajectory and associated ethnic differences among adolescent smokers seeking cessation treatment
    Miqun L Robinson
    Teen Tobacco Addiction Treatment Research Clinic, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    J Adolesc Health 35:217-24. 2004
    ....
  26. ncbi request reprint The cannabinoid CB1 receptor antagonist rimonabant attenuates the hypotensive effect of smoked marijuana in male smokers
    David A Gorelick
    Clinical Pharmacology and Therapeutics Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, MD 21224, USA
    Am Heart J 151:754.e1-754.e5. 2006
    ..In human studies, activation of CB1 receptors by cannabis or its active ingredient, Delta9-tetrahydrocannabinol (THC), has modest and inconsistent effects on BP...
  27. ncbi request reprint Sensitivity and specificity of the Cozart microplate EIA cocaine oral fluid at proposed screening and confirmation cutoffs
    Insook Kim
    Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 5500 Nathan Shock Dr, Baltimore, MD 21224, USA
    Clin Chem 49:1498-503. 2003
    ....
  28. ncbi request reprint Health and performance related reasons for wanting to quit: gender differences among teen smokers
    A Thiri Aung
    National Institutes of Health, National Institute on Drug Abuse, Intramural Research Program, Teen Tobacco Addiction Treatment Research Clinic, Baltimore, Maryland 21224, USA
    Subst Use Misuse 38:1095-107. 2003
    ..78, p = 0.02). Recognizing the greater concern for performance-related issues among boys is important for designing and engaging young smokers into cessation interventions...
  29. ncbi request reprint Weight gain, related concerns, and treatment outcomes among adolescent smokers enrolled in cessation treatment
    Elissa Thorner-Bantug
    Department of Health and Human Resources, National Institutes of Health, National Institute on Drug Abuse Intramural Research Program, Biomedical Research Center, Baltimore, Maryland, USA
    J Natl Med Assoc 101:1009-14. 2009
    ..Adolescents who quit smoking gained no more weight during the trial than those who smoked...
  30. ncbi request reprint Safety and efficacy of the nicotine patch and gum for the treatment of adolescent tobacco addiction
    Eric T Moolchan
    Teen Tobacco Addiction Research Clinic, Clinical Pharmacology and Therapeutics Research Branch, National Institute on Drug Abuse, Intramural Research Program, 5500 Nathan Shock Dr, Baltimore, Maryland 21224, USA
    Pediatrics 115:e407-14. 2005
    ..To determine the safety and efficacy of the nicotine patch and gum for adolescents who want to quit smoking...
  31. pmc Heart rate and blood pressure responses to tobacco smoking among African-American adolescents
    Eric T Moolchan
    National Institute on Drug Abuse, Intramural Research Program National Institutes of Health, U S Department of Health and Human Services, S 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    J Natl Med Assoc 96:767-71. 2004
    ..These preliminary findings warrant extension to a broader group of nontreatment-seeking adolescent smokers of both ethnicities...
  32. ncbi request reprint Effect of tobacco deprivation on the attentional blink in rapid serial visual presentation
    Adrienne Heinz
    Clinical Pharmacology and Therapeutics Branch, National Institute on Drug Abuse, NIH, Baltimore, Maryland 21224, USA
    Hum Psychopharmacol 22:89-96. 2007
    ..These results suggest that the AB is influenced by stimulus duration, but not by 12 h of tobacco deprivation...
  33. pmc Tobacco craving in smokers with and without schizophrenia
    Suzanne Lo
    Nicotine Psychopharmacology Section, National Institute on Drug Abuse, NIH Intramural Research Program, 251 Bayview Blvd, Baltimore, MD 21224, United States
    Schizophr Res 127:241-5. 2011
    ....
  34. pmc Early tobacco smoking in adolescents with externalizing disorders: inferences for reward function
    Will M Aklin
    Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Nicotine Tob Res 11:750-5. 2009
    ..The present study examined the relationship between the externalizing disorders and the temporal progression of smoking among adolescent smokers...
  35. ncbi request reprint Quit attempts among African American teenage smokers seeking treatment: gender differences
    Eric T Moolchan
    Department of Health and Human Services, National Institute on Drug Abuse, Intramural Research Program, Clinical Pharmacology and Therapeutics Research Branch, National Institutes of Health, Baltimore, MD 21224, USA
    Prev Med 39:1180-6. 2004
    ....
  36. ncbi request reprint Delta(9)-tetrahydrocannabinol, 11-hydroxy-delta(9)-tetrahydrocannabinol and 11-nor-9-carboxy-delta(9)-tetrahydrocannabinol in human plasma after controlled oral administration of cannabinoids
    Robert S Goodwin
    Chemistry and Drug Metabolism Section, IRP, NIDA, NIH, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Ther Drug Monit 28:545-51. 2006
    ..There was a significant correlation between body mass index and Cmax and body mass index and number of specimens positive for THC and 11-OH-THC...
  37. ncbi request reprint Plasma and oral fluid pharmacokinetics and pharmacodynamics after oral codeine administration
    Insook Kim
    Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse NIH, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Clin Chem 48:1486-96. 2002
    ....
  38. ncbi request reprint Urinary cannabinoid detection times after controlled oral administration of delta9-tetrahydrocannabinol to humans
    Richard A Gustafson
    Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Clin Chem 49:1114-24. 2003
    ....
  39. ncbi request reprint Quantitative comparisons between a nicotine delivery device (Eclipse) and conventional cigarette smoking
    Eun M Lee
    National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD, USA
    Nicotine Tob Res 6:95-102. 2004
    ..The findings further validate the use of a topography device as an effective instrument to quantify smoke exposure...
  40. ncbi request reprint Adolescents in smoking cessation treatment: relationship between externalizing symptoms, smoking history and outcome
    Eric T Moolchan
    TTATRC, NIDA IRP, NIH, DHHS, Baltimore, MD 21224, USA
    Psychiatry Res 152:281-5. 2007
    ..Our findings highlight the importance of addressing externalizing behaviors in adolescent smoking cessation programs...
  41. ncbi request reprint Shorter time to first cigarette of the day in menthol adolescent cigarette smokers
    Charles C Collins
    National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Department of Health and Human Services, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Addict Behav 31:1460-4. 2006
    ..Further study in a broader sample of adolescent smokers is warranted to elucidate the mechanisms underlying the effects of menthol smoking for youths...
  42. pmc Time spent with smoking parents and smoking topography in adolescents
    Charles C Collins
    National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Department of Health and Human Services, Baltimore, MD 21224, USA
    Addict Behav 33:1594-7. 2008
    ..17). Future research with a larger non-treatment seeking sample of adolescents aimed at preventing tobacco smoking related diseases should further examine parental influences on adolescent smoking, including potential modeling effects...
  43. ncbi request reprint Identifying health disparities across the tobacco continuum
    Pebbles Fagan
    National Cancer Institute, Bethesda, MD 20892 7337, USA
    Addiction 102:5-29. 2007
    ..The paper also discusses how work-force diversity, inequities in research practice and knowledge allocation and inequalities in access to and quality of health care are fundamental to addressing disparities in health...
  44. doi request reprint Nicotine dependence and quitting behaviors among menthol and non-menthol smokers with similar consumptive patterns
    Pebbles Fagan
    National Cancer Institute, Tobacco Control Research Branch, Behavioral Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892 7337, USA
    Addiction 105:55-74. 2010
    ..This study examines the associations between usual cigarette brand (i.e. menthol, non-menthol) and markers for nicotine dependence and quitting behaviors...
  45. ncbi request reprint The Fagerstrom Test for Nicotine Dependence and the Diagnostic Interview Schedule: do they diagnose the same smokers?
    Eric T Moolchan
    Clinical Pharmacology and Therapeutics Research Branch, National Institutes of Health, National Institute on Drug Abuse Intramural Research Program, Baltimore MD, 21224, USA
    Addict Behav 27:101-13. 2002
    ..Disagreements between the FTND and the DSM are likely to become greater with the changes in the DSM-IV...
  46. ncbi request reprint Sensory and physiologic effects of menthol and non-menthol cigarettes with differing nicotine delivery
    Wallace B Pickworth
    Clinical Pharmacology Branch, National Institute on Drug Abuse, Intramural Research Program, Addiction Research Center, National Institutes of Health, PO Box 5180, Baltimore, MD 21224, USA
    Pharmacol Biochem Behav 71:55-61. 2002
    ..These results illustrate the importance of threshold levels of nicotine on subjective responses to cigarette smoking...
  47. ncbi request reprint Clove cigarette smoking: biochemical, physiological, and subjective effects
    Jennifer L Malson
    National Institute on Drug Abuse, Intramural Research Program, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Pharmacol Biochem Behav 74:739-45. 2003
    ..Taste satisfaction, aromatic odor, and novelty may contribute to their appeal to young smokers...
  48. doi request reprint Decision-making and facial emotion recognition as predictors of substance-use initiation among adolescents
    Monique Ernst
    Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Addict Behav 35:286-9. 2010
    ..In conclusion, adolescents who initiate drug use present vulnerability in the form of bias towards negative emotion but not toward decisions that involve risk...
  49. ncbi request reprint Research on tobacco use among teenagers: ethical challenges
    Eric T Moolchan
    Teen Tobacco Addiction Treatment Research Clinic, National Institutes of Health, National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland 21224, USA
    J Adolesc Health 30:409-17. 2002
    ..Context-specific ethical adjustments and alternative perspectives are likely to be needed if we are to overcome procedural difficulties in conducting teen smoking studies...
  50. ncbi request reprint A factor analysis of the Fagerström Test for Nicotine Dependence (FTND)
    Aleksandras Radzius
    Intramural Research Program, National Institute on Drug Abuse National Institutes of Health Baltimore MD 21224, USA
    Nicotine Tob Res 5:255-40. 2003
    ..These two dimensions may provide indirect assessment of a smoker's daily nicotine intake. Testing this hypothesis requires correlation of biomarkers and responses to specific items of the FTND...
  51. ncbi request reprint Duration of detectable methamphetamine and amphetamine excretion in urine after controlled oral administration of methamphetamine to humans
    Jonathan M Oyler
    Chemistry and Drug Metabolism Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 5500 Nathan Shock Dr, Baltimore, MD 21224, USA
    Clin Chem 48:1703-14. 2002
    ..We determined the urinary excretion of MAMP after oral ingestion and examined the effect of using lower cutoffs on detection of exposure...
  52. ncbi request reprint Urinary elimination of cocaine metabolites in chronic cocaine users during cessation
    Kenzie L Preston
    Clinical Pharmacology and Therapeutics Research Branch, Intramural Research Program, National Institute on Drug Abuse, Baltimore, Maryland 21224, USA
    J Anal Toxicol 26:393-400. 2002
    ....
  53. ncbi request reprint Treatment of adolescent tobacco smokers: issues and opportunities for exposure reduction approaches
    Eric T Moolchan
    Intramural Research Program, Clinical Pharmacology and Therapeutics Research Branch, National Institute on Drug Abuse, National Institutes of Health, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Drug Alcohol Depend 70:223-32. 2003
    ....
  54. ncbi request reprint Cozart RapiScan Oral Fluid Drug Testing System: an evaluation of sensitivity, specificity, and efficiency for cocaine detection compared with ELISA and GC-MS following controlled cocaine administration
    Erin A Kolbrich
    Chemistry and Drug Metabolism Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 5500 Nathan Shock Drive, Baltimore, Maryland 21224, USA
    J Anal Toxicol 27:407-11. 2003
    ..4%, 92.2%, and 90.7%, respectively. Cozart RapiScan had performance similar to the COC ELISA assay for the detection of cocaine exposure and suitable sensitivity and specificity at the proposed SAMHSA cutoffs...
  55. ncbi request reprint Tobacco Craving Questionnaire: reliability and validity of a new multifactorial instrument
    Stephen J Heishman
    Clinical Pharmacology and Therapeutics Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore MD 21224, USA
    Nicotine Tob Res 5:645-54. 2003
    ..These preliminary data suggest that the TCQ is a reliable and valid instrument for assessing tobacco craving in individuals not attempting to reduce or quit smoking...
  56. ncbi request reprint EEG effects of conventional and denicotinized cigarettes in a spaced smoking paradigm
    Wallace B Pickworth
    NIDA, Intramural Research Program, 5500 Nathan Shock Drive, P O Box 5180, Baltimore, MD 21224, USA
    Brain Cogn 53:75-81. 2003
    ..The results indicate that nicotine delivery, recentness and the process of smoking importantly influence the EEG; other, non-nicotine components of tobacco smoke may also exert EEG effects...
  57. ncbi request reprint Smoking topography: reliability and validity in dependent smokers
    Eun M Lee
    National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore MD 21224, USA
    Nicotine Tob Res 5:673-9. 2003
    ..Overall, the data from these two small-sample studies suggest that smoking topography provides a valid and reliable index of conventional smoking and an indirect measure of smoke exposure...
  58. ncbi request reprint Behavioral predictors of substance-use initiation in adolescents with and without attention-deficit/hyperactivity disorder
    Monique Ernst
    Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892 2670, USA
    Pediatrics 117:2030-9. 2006
    ..Our goal was to examine substance-use initiation in healthy adolescents and in adolescents who have been diagnosed with attention-deficit/hyperactivity disorder...
  59. ncbi request reprint Methamphetamine and amphetamine pharmacokinetics in oral fluid and plasma after controlled oral methamphetamine administration to human volunteers
    Raf J F Schepers
    Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, NIH, 5500 Nathan Shock Dr, Baltimore, MD 21224, USA
    Clin Chem 49:121-32. 2003
    ..Methamphetamine (METH) and amphetamine (AMP) concentrations in 200 plasma and 590 oral fluid specimens were used to evaluate METH pharmacokinetics and pharmacodynamics after oral administration of sustained-release METH...
  60. ncbi request reprint Characteristics of African American teenage smokers who request cessation treatment: implications for addressing health disparities
    Eric T Moolchan
    Intramural Research Program, Teen Tobacco Addiction Treatment Research Clinic, Clinical Pharmacology and Therapeutics Research Branch, National Institute on Drug Abuse NIH, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Arch Pediatr Adolesc Med 157:533-8. 2003
    ..Ethnoracial disparities in both tobacco-related mortality and treatment outcome for smoking cessation have been reported among adults, but there is a dearth of information on ethnoracial differences among adolescent smokers...
  61. ncbi request reprint Sensitivity, specificity, and efficiency in detecting opiates in oral fluid with the Cozart Opiate Microplate EIA and GC-MS following controlled codeine administration
    Allan J Barnes
    Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland 21124, USA
    J Anal Toxicol 27:402-7. 2003
    ..In addition, the data, collected following controlled oral codeine administration, may aid in the interpretation of opiate oral fluid test results and in the selection of appropriate oral fluid screening and confirmation cutoffs...
  62. ncbi request reprint Urinary pharmacokinetics of 11-nor-9-carboxy-delta9-tetrahydrocannabinol after controlled oral delta9-tetrahydrocannabinol administration
    Richard A Gustafson
    Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 5500 Nathan Shock Drive, Baltimore, Maryland 21224, USA
    J Anal Toxicol 28:160-7. 2004
    ..These controlled drug administration data should assist in the interpretation of urine cannabinoid results and provide clinicians with valuable information for future pharmacological studies...
  63. ncbi request reprint History of marijuana use and tobacco smoking topography in tobacco-dependent adolescents
    A Thiri Aung
    Clinical Pharmacology and Treatment Research Branch, National Institutes of Health, National Institute on Drug Abuse, Intramural Research Program, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Addict Behav 29:699-706. 2004
    ..Our findings in adolescent smokers are consistent with results from adult studies in which history of MJ smoking was not associated with changes in tobacco smoking topography...
  64. ncbi request reprint Time spent with friends who smoke and quit attempts among teen smokers
    Daniel N Jones
    Clinical Pharmacology and Therapeutics Research Branch, National Institute on Drug Abuse, National Institutes of Health, Bethesda, MD, USA
    Addict Behav 29:723-9. 2004
    ..55, P=.0085) but not with their duration, suggesting a potential relationship between an adolescent's affiliation with smoking peers, smoking identity, and fewer quit attempts...
  65. ncbi request reprint Effect of tobacco craving cues on memory encoding and retrieval in smokers
    Stephen J Heishman
    Clinical Pharmacology and Therapeutics Branch, National Institute on Drug Abuse, NIH, DHHS, Intramural Research Program, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Addict Behav 31:1116-21. 2006
    ..There was a trend toward impaired working memory following craving scripts compared with neutral scripts. These data support the hypothesis that the cognitive underpinnings of encoding and retrieval processes are distinct...
  66. ncbi request reprint Nicotine delivery from smoking bidis and an additive-free cigarette
    Jennifer L Malson
    Intramural Research Program, National Institute on Drug Abuse, Baltimore, Maryland 21224, USA
    Nicotine Tob Res 4:485-90. 2002
    ..These results do not support an emerging belief that bidi cigarettes are safer than conventional brands...
  67. ncbi request reprint Determination of total and free concentrations of the enantiomers of methadone and its metabolite (2-ethylidene-1,5-dimethyl-3,3-diphenyl-pyrrolidine) in human plasma by enantioselective liquid chromatography with mass spectrometric detection
    Maria Esther Rodriguez-Rosas
    Bioanalytical and Drug Discovery Unit, Gerontology Research Center, National Institute on Aging, National Institutes of Health, 5600 Nathan Shock Drive, Baltimore, MD 21224 6825, USA
    J Chromatogr A 1073:237-48. 2005
    ..S.D. for the intra- and inter-day precision of the method were < 5.3% and the R.S.D. for accuracy was < 5.0%. The method was used to analyze plasma samples obtained from patients enrolled in a Met-maintenance program...
  68. ncbi request reprint Disposition of cocaine and its metabolites in human sweat after controlled cocaine administration
    Sherri L Kacinko
    Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA
    Clin Chem 51:2085-94. 2005
    ..Sweat testing is a noninvasive technique for monitoring drug exposure in treatment, criminal justice, and employment settings...
  69. ncbi request reprint Adolescent menthol smokers: will they be a harder target for cessation?
    Eric T Moolchan
    Teen Tobacco Addiction Treatment Research Clinic, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, MD 21224, USA
    Nicotine Tob Res 6:S93-5. 2004
    ..These findings of overwhelming menthol preference in a treatment-seeking sample of adolescents warrant further research on the developmental trajectory, cessation, and health-related impact of menthol smoking by youth...
  70. ncbi request reprint Differences in risk-taking propensity across inner-city adolescent ever- and never-smokers
    C W Lejuez
    Department of Psychlogy, University of Maryland, College Park, MD 20742, USA
    Nicotine Tob Res 7:71-9. 2005
    ..e., self-report measures and behavioral tasks) to identify adolescents' risk-taking susceptibilities and engagement in smoking and other risk-taking behaviors...
  71. ncbi request reprint Performance characteristics of the Cozart RapiScan Oral Fluid Drug Testing System for opiates in comparison to ELISA and GC/MS following controlled codeine administration
    Sherri L Kacinko
    Chemistry and Drug Metabolism Section, Intramural Research Program, NIDA, NIH, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
    Forensic Sci Int 141:41-8. 2004
    ....
  72. pmc Measuring nicotine intake among highly-dependent adolescent smokers: comparability of saliva and plasma cotinine concentrations
    Craig S Parzynski
    DHHS NIH NIDA IRP, Baltimore, Maryland 21224, United States
    Pharmacol Biochem Behav 89:145-9. 2008
    ..93, p=0.058). Future research should seek to further validate saliva-to-plasma cotinine concentration ratios in adolescents as well as characterize saliva-to-plasma concentration differences and their underlying mechanisms...
  73. ncbi request reprint Simultaneous quantification of methamphetamine, cocaine, codeine, and metabolites in skin by positive chemical ionization gas chromatography-mass spectrometry
    Wonkyung Yang
    National Institute of Scientific Investigation, 331 1 Shinwol 7 dong, Yangcheon Gu, Seoul 158 707, Republic of Korea
    J Chromatogr B Analyt Technol Biomed Life Sci 833:210-8. 2006
    ..999 and concentrations +/-20% of target. Intra- and inter-run precisions were <10%. This procedure should be useful for postmortem analysis; data are included on drug concentrations in skin after controlled drug administration...
  74. pmc Associations between Cloninger's temperament dimensions and acute tobacco withdrawal
    Adam M Leventhal
    Center for Alcohol and Addiction Studies, Brown University, Box G S121, Providence, RI 02912, USA
    Addict Behav 32:2976-89. 2007
    ..Smokers with different temperaments display different patterns of acute tobacco withdrawal, and may benefit from treatments matched to their particular abstinence profile...
  75. ncbi request reprint Youth tobacco control research and activities in the United States: the current national landscape
    Jonathan P Winickoff
    MGH Center for Child and Health Policy, Massachusetts General Hospital for Children, Boston, MA 02114, USA
    Nicotine Tob Res 5:435-54. 2003
    ..This synthesis of current research, funding sources, programmatic activities, and collaborations in the United States will be a valuable resource for clinicians, tobacco control advocates, researchers, and program planners...
  76. ncbi request reprint Sex-based and hormonal contraception effects on the metabolism of nicotine among adolescent tobacco-dependent smokers
    Ivan Berlin
    Groupe Hospitalier Universitaire Pitié Salpêtrière, Universite Pierre et Marie Curie, Paris 6 and INSERM U 677, Paris, France
    Nicotine Tob Res 9:493-8. 2007
    ..Prospective controlled studies are needed to further evaluate the role of hormonal contraception in patterns of adolescent smoking and nicotine metabolism...
  77. ncbi request reprint Youth tobacco use: a global perspective for child health care clinicians
    Alexander V Prokhorov
    Department of Behavioral Science, University of Texas M D Anderson Cancer Center, Houston, Texas 77230 1439, USA
    Pediatrics 118:e890-903. 2006
    ..In addition, we provide a review of currently available funding opportunities for development and implementation of youth tobacco-control programs...
  78. pmc Gender differences in acute tobacco withdrawal: effects on subjective, cognitive, and physiological measures
    Adam M Leventhal
    Department of Behavioral Science, University of Texas M D Anderson Cancer Center, TX, USA
    Exp Clin Psychopharmacol 15:21-36. 2007
    ..10). These findings suggest that there are qualitative gender differences in the acute tobacco withdrawal syndrome that may underlie gender-specific smoking patterns...