Research Topics
| E T MoolchanSummaryAffiliation: National Institutes of Health Country: USA Publications
| Collaborators
|
Detail Information
Publications
Research on tobacco use among teenagers: ethical challengesEric T Moolchan
Teen Tobacco Addiction Treatment Research Clinic, National Institutes of Health, National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland 21224, USA
J Adolesc Health 30:409-17. 2002..Context-specific ethical adjustments and alternative perspectives are likely to be needed if we are to overcome procedural difficulties in conducting teen smoking studies...
Adolescents in smoking cessation treatment: relationship between externalizing symptoms, smoking history and outcomeEric T Moolchan
TTATRC, NIDA IRP, NIH, DHHS, Baltimore, MD 21224, USA
Psychiatry Res 152:281-5. 2007..Our findings highlight the importance of addressing externalizing behaviors in adolescent smoking cessation programs...
Treatment of adolescent tobacco smokers: issues and opportunities for exposure reduction approachesEric T Moolchan
Intramural Research Program, Clinical Pharmacology and Therapeutics Research Branch, National Institute on Drug Abuse, National Institutes of Health, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
Drug Alcohol Depend 70:223-32. 2003....
Adolescent menthol smokers: will they be a harder target for cessation?Eric T Moolchan
Teen Tobacco Addiction Treatment Research Clinic, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, MD 21224, USA
Nicotine Tob Res 6:S93-5. 2004..These findings of overwhelming menthol preference in a treatment-seeking sample of adolescents warrant further research on the developmental trajectory, cessation, and health-related impact of menthol smoking by youth...
Safety and efficacy of the nicotine patch and gum for the treatment of adolescent tobacco addictionEric T Moolchan
Teen Tobacco Addiction Research Clinic, Clinical Pharmacology and Therapeutics Research Branch, National Institute on Drug Abuse, Intramural Research Program, 5500 Nathan Shock Dr, Baltimore, Maryland 21224, USA
Pediatrics 115:e407-14. 2005..To determine the safety and efficacy of the nicotine patch and gum for adolescents who want to quit smoking...
Quit attempts among African American teenage smokers seeking treatment: gender differencesEric T Moolchan
Department of Health and Human Services, National Institute on Drug Abuse, Intramural Research Program, Clinical Pharmacology and Therapeutics Research Branch, National Institutes of Health, Baltimore, MD 21224, USA
Prev Med 39:1180-6. 2004....
Heart rate and blood pressure responses to tobacco smoking among African-American adolescentsEric T Moolchan
National Institute on Drug Abuse, Intramural Research Program National Institutes of Health, U S Department of Health and Human Services, S 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
J Natl Med Assoc 96:767-71. 2004..These preliminary findings warrant extension to a broader group of nontreatment-seeking adolescent smokers of both ethnicities...
The Fagerstrom Test for Nicotine Dependence and the Diagnostic Interview Schedule: do they diagnose the same smokers?Eric T Moolchan
Clinical Pharmacology and Therapeutics Research Branch, National Institutes of Health, National Institute on Drug Abuse Intramural Research Program, Baltimore MD, 21224, USA
Addict Behav 27:101-13. 2002..Disagreements between the FTND and the DSM are likely to become greater with the changes in the DSM-IV...
Recent marijuana blunt smoking impacts carbon monoxide as a measure of adolescent tobacco abstinenceEric T Moolchan
Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Intramural Research Program, Baltimore, Maryland 21224, USA
Subst Use Misuse 40:231-40. 2005..013). Blunt occasions also tended to be associated with the more youth-appropriate cutoff CO > or = 6 ppm, compared to non-MJ occasions (p =0.054). Blunt smoking impacted the interpretation of measures of exhaled CO for tobacco cessation...
Therapeutic drug monitoring in methadone maintenance: choosing a matrixE T Moolchan
Department of Health and Human Services, National Institute of Health, National Institute of Drug Abuse, Baltimore, MD 21224, USA
J Addict Dis 20:55-73. 2001..However, saliva methadone concentrations are influenced by salivary pH, and future studies are needed to determine how to control for that. Administrative, medical, and social implications of methadone TDM are briefly discussed...
Smoking rates and topography predict adolescent smoking cessation following treatment with nicotine replacement therapyFrederick H Franken
Department of Health and Human Services, National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD 21224, USA
Cancer Epidemiol Biomarkers Prev 15:154-7. 2006..If confirmed in a larger sample, our findings suggest that puff topography, and possibly CPD, might predict cessation outcome better than Fagerström scores in adolescent smokers...
Tobacco smoking trajectory and associated ethnic differences among adolescent smokers seeking cessation treatmentMiqun L Robinson
Teen Tobacco Addiction Treatment Research Clinic, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
J Adolesc Health 35:217-24. 2004..Ethnic differences in smoking trajectory uncovered in this report call for ethnically tailored interventions to reduce youth smoking...
Sensitivity and specificity of the Cozart microplate EIA cocaine oral fluid at proposed screening and confirmation cutoffsInsook Kim
Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 5500 Nathan Shock Dr, Baltimore, MD 21224, USA
Clin Chem 49:1498-503. 2003..Sensitivity, specificity, and efficiency were >84% for both cutoffs, but 92 additional true-positive samples were identified with the SAMHSA cutoffs...
Reasons for wanting to quit: ethnic differences among cessation-seeking adolescent smokersEmily J Luther
Teen Tobacco Addiction Research Clinic, Clinical Pharmacology and Therapeutics Research Branch, National Institute on Drug Abuse, Baltimore, Maryland, USA
Ethn Dis 16:739-43. 2006..001). CONCLUSIONS: The development of culturally tailored messages may help enhance smoking cessation efforts among adolescents...
Health and performance related reasons for wanting to quit: gender differences among teen smokersA Thiri Aung
National Institutes of Health, National Institute on Drug Abuse, Intramural Research Program, Teen Tobacco Addiction Treatment Research Clinic, Baltimore, Maryland 21224, USA
Subst Use Misuse 38:1095-107. 2003..78, p = 0.02). Recognizing the greater concern for performance-related issues among boys is important for designing and engaging young smokers into cessation interventions...
Correlates of expired air carbon monoxide: effect of ethnicity and relationship with saliva cotinine and nicotineI Berlin
Clinical Pharmacology and Treatment Research Branch, Division of Intramural Research, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland, USA
Nicotine Tob Res 3:325-31. 2001..To assess the accuracy of expired air carbon monoxide (CO) measurement vs. saliva cotinine and nicotine and to estimate the degree of misclassifications of smoking status as a function of ethnicity...
Placebo cigarettes in a spaced smoking paradigmNicole C Eid
National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD, USA
Pharmacol Biochem Behav 81:158-64. 2005..However, the nicotine yield of the cigarette did not influence these patterns. It is concluded that acute tobacco cravings can be repeatedly diminished with cigarettes that do not deliver nicotine...
Adolescents with conduct disorder: early smoking and treatment requestsKara S Bagot
The National Institute on Drug Abuse, Intramural Research Program, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
Am J Addict 16:62-6. 2007..These findings suggest that in addition to addressing disruptive behaviors, early prevention and access to interventions for tobacco use are needed for youths with CD...
Quantitative comparisons between a nicotine delivery device (Eclipse) and conventional cigarette smokingEun M Lee
National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD, USA
Nicotine Tob Res 6:95-102. 2004..The findings further validate the use of a topography device as an effective instrument to quantify smoke exposure...
Plasma and oral fluid pharmacokinetics and pharmacodynamics after oral codeine administrationInsook Kim
Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse/NIH, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
Clin Chem 48:1486-96. 2002..These controlled drug administration data should aid in the interpretation of oral fluid codeine results...
Adolescent smokers screened for a nicotine replacement treatment trial: correlates of eligibility and enrollmentMiqun L Robinson
Clinical Pharmacology and Treatment Research Branch, National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, U.S. Department of Health and Human Services, MD 21224, USA
Nicotine Tob Res 8:447-54. 2006..3%) enrolled. Results underscore the need for screening instruments that are measurement-invariant across ethnicities and gender, and for enrollment strategies that maximize inclusion of eligible participants...
Tobacco craving predicts lapse to smoking among adolescent smokers in cessation treatmentKara S Bagot
National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD 21224, USA
Nicotine Tob Res 9:647-52. 2007..Thus monitoring and addressing craving appears useful to increase the success of adolescent smoking cessation...
Urinary cannabinoid detection times after controlled oral administration of delta9-tetrahydrocannabinol to humansRichard A Gustafson
Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
Clin Chem 49:1114-24. 2003..Urine tests have a high likelihood of being positive after Marinol therapy. The Emit II and DRI assays had adequate sensitivity and specificity, but the CEDIA assay failed to detect many true-positive specimens...
A factor analysis of the fagerstrom tolerance questionnaireA Radzius
Clinical Pharmacology and Therapeutics Research Branch, Division of Intramural Research, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA
Addict Behav 26:303-10. 2001....
Behavioral and neural consequences of prenatal exposure to nicotineM Ernst
Brain Imaging Center in the Neuroimaging Branch of the Intramural Research Program of the National Institute on Drug Abuse, Bethesda, MD 20892 0135, USA
J Am Acad Child Adolesc Psychiatry 40:630-41. 2001..The relatively high rate of tobacco smoking among pregnant women (25% of all pregnancies in the U.S.) underlines the seriousness of these concerns...
Early tobacco smoking in adolescents with externalizing disorders: inferences for reward functionWill M Aklin
Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Nicotine Tob Res 11:750-5. 2009..The present study examined the relationship between the externalizing disorders and the temporal progression of smoking among adolescent smokers...
Decision-making and facial emotion recognition as predictors of substance-use initiation among adolescentsMonique Ernst
Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
Addict Behav 35:286-9. 2010..In conclusion, adolescents who initiate drug use present vulnerability in the form of bias towards negative emotion but not toward decisions that involve risk...
Nicotine replacement therapy use among adolescent smokers seeking cessation treatmentMaria Botello-Harbaum
National Institutes of Health, National Institute of Child Health and Human Development, Intramural Research Program, USA
Ethn Dis 20:180-4. 2010..To examine the correlates of prior nicotine replacement therapy (NRT) in an urban sample of adolescent smokers seeking smoking cessation treatment...
Adolescent nicotine metabolism: ethnoracial differences among dependent smokersEric T Moolchan
National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland 21224, USA
Ethn Dis 16:239-43. 2006..Our results underscore the need for measures independent of consumption for determining degree of nicotine dependence and treatment selection across ethnicities, even among youths...
The cannabinoid CB1 receptor antagonist rimonabant attenuates the hypotensive effect of smoked marijuana in male smokersDavid A Gorelick
Clinical Pharmacology and Therapeutics Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, MD 21224, USA
Am Heart J 151:754.e1-754.e5. 2006..In human studies, activation of CB1 receptors by cannabis or its active ingredient, Delta9-tetrahydrocannabinol (THC), has modest and inconsistent effects on BP...
Nicotine dependence and quitting behaviors among menthol and non-menthol smokers with similar consumptive patternsPebbles Fagan
National Cancer Institute, Tobacco Control Research Branch, Behavioral Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892 7337, USA
Addiction 105:55-74. 2010..This study examines the associations between usual cigarette brand (i.e. menthol, non-menthol) and markers for nicotine dependence and quitting behaviors...
Dose-related enhancement of mood and cognition in smokers administered nicotine nasal sprayCarol S Myers
Clinical Pharmacology and Therapeutics Branch, National Institute on Drug Abuse, NIH Intramural Research Program, Baltimore, MD 21224, USA
Neuropsychopharmacology 33:588-98. 2008..These results provide an unequivocal determination that nicotine enhanced attentional and computational abilities in nondeprived smokers and suggest these cognitive domains as substrates for novel therapeutic indications...
Alcohol use and tobacco abstinence among adolescents in cessation treatment: preliminary findingsMaria Jaszyna Gasior
National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Department of Health and Human Services, Baltimore, USA
Addict Behav 32:617-21. 2007..If confirmed in a larger group of adolescents, our findings suggest that youths attempting to quit smoking should abstain from alcohol...
Promoting abstinence from cocaine and heroin with a methadone dose increase and a novel contingencyDavid H Epstein
Treatment Section, Clinical Pharmacology and Therapeutics Branch, Intramural Research Branch of the National Institute on Drug Abuse, 251 Bayview Blvd, Suite 200, Baltimore, MD 21224, USA
Drug Alcohol Depend 101:92-100. 2009..For a split contingency to promote simultaneous abstinence from cocaine and heroin, a relatively high dose of methadone appears necessary but not sufficient; an increase in overall incentive amount may also be required...
Measuring nicotine intake among highly-dependent adolescent smokers: comparability of saliva and plasma cotinine concentrationsCraig S Parzynski
DHHS NIH NIDA IRP, Baltimore, Maryland 21224, United States
Pharmacol Biochem Behav 89:145-9. 2008..93, p=0.058). Future research should seek to further validate saliva-to-plasma cotinine concentration ratios in adolescents as well as characterize saliva-to-plasma concentration differences and their underlying mechanisms...
Excretion of methamphetamine and amphetamine in human sweat following controlled oral methamphetamine administrationAllan J Barnes
Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
Clin Chem 54:172-80. 2008..Understanding methamphetamine (MAMP) and amphetamine (AMP) excretion in sweat is important for interpreting sweat and hair testing results in judicial, workplace, and drug treatment settings...
Addressing tobacco-related health disparitiesEric T Moolchan
National Institute on Drug Abuse, Baltimore, MD 21224, USA
Addiction 102:30-42. 2007..We will show the importance of an approach that integrates the human life-cycle (developmental) and tobacco addiction cycle (behavioral) for interventions that address group-specific vulnerabilities...
Identifying health disparities across the tobacco continuumPebbles Fagan
National Cancer Institute, Bethesda, MD 20892 7337, USA
Addiction 102:5-29. 2007..The paper also discusses how work-force diversity, inequities in research practice and knowledge allocation and inequalities in access to and quality of health care are fundamental to addressing disparities in health...
Cannabinoid concentrations in hair from documented cannabis usersMarilyn A Huestis
Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, United States
Forensic Sci Int 169:129-36. 2007..01, Pearson's product moment correlation). Using an immunoassay cutoff concentration of 5 pg THC equiv./mg hair, 83% of specimens that screened positive were confirmed by GCMSMS at a cutoff concentration of 0.1 pg THCCOOH/mg hair...
Consistency of subjective responses to imagery-induced tobacco craving over multiple sessionsDustin C Lee
Clinical Pharmacology and Therapeutics Branch, National Institute on Drug Abuse, Intramural Research Program, NIH, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
Addict Behav 32:2130-9. 2007..These results have practical implications for examining individual differences in sensitivity to smoking cues and for studies involving repeated measurement of elicited craving over time...
Ethnic differences among adolescents seeking smoking cessation treatment: a structural analysis of responses on the Fagerström Test for Nicotine DependenceJennifer R Schroeder
Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD 21224, USA
Nicotine Tob Res 9:137-45. 2007..However, MIMIC modeling indicated differential reporting for three out of six items, suggesting that the FTND may not measure nicotine dependence equivalently for White and African American youth...
Delta(9)-tetrahydrocannabinol, 11-hydroxy-delta(9)-tetrahydrocannabinol and 11-nor-9-carboxy-delta(9)-tetrahydrocannabinol in human plasma after controlled oral administration of cannabinoidsRobert S Goodwin
Chemistry and Drug Metabolism Section, IRP, NIDA, NIH, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
Ther Drug Monit 28:545-51. 2006..There was a significant correlation between body mass index and Cmax and body mass index and number of specimens positive for THC and 11-OH-THC...
Methamphetamine and amphetamine pharmacokinetics in oral fluid and plasma after controlled oral methamphetamine administration to human volunteersRaf J F Schepers
Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, NIH, 5500 Nathan Shock Dr, Baltimore, MD 21224, USA
Clin Chem 49:121-32. 2003..Methamphetamine (METH) and amphetamine (AMP) concentrations in 200 plasma and 590 oral fluid specimens were used to evaluate METH pharmacokinetics and pharmacodynamics after oral administration of sustained-release METH...
Smoking topography: reliability and validity in dependent smokersEun M Lee
National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Baltimore MD 21224, USA
Nicotine Tob Res 5:673-9. 2003..Overall, the data from these two small-sample studies suggest that smoking topography provides a valid and reliable index of conventional smoking and an indirect measure of smoke exposure...
Characteristics of African American teenage smokers who request cessation treatment: implications for addressing health disparitiesEric T Moolchan
Intramural Research Program, Teen Tobacco Addiction Treatment Research Clinic, Clinical Pharmacology and Therapeutics Research Branch, National Institute on Drug Abuse/NIH, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
Arch Pediatr Adolesc Med 157:533-8. 2003..Our findings also highlight the importance of ethnocultural issues in treatment research that aims to address health disparities...
EEG effects of conventional and denicotinized cigarettes in a spaced smoking paradigmWallace B Pickworth
NIDA, Intramural Research Program, 5500 Nathan Shock Drive, P O Box 5180, Baltimore, MD 21224, USA
Brain Cogn 53:75-81. 2003..The results indicate that nicotine delivery, recentness and the process of smoking importantly influence the EEG; other, non-nicotine components of tobacco smoke may also exert EEG effects...
Duration of detectable methamphetamine and amphetamine excretion in urine after controlled oral administration of methamphetamine to humansJonathan M Oyler
Chemistry and Drug Metabolism Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 5500 Nathan Shock Dr, Baltimore, MD 21224, USA
Clin Chem 48:1703-14. 2002..We determined the urinary excretion of MAMP after oral ingestion and examined the effect of using lower cutoffs on detection of exposure...
Cozart RapiScan Oral Fluid Drug Testing System: an evaluation of sensitivity, specificity, and efficiency for cocaine detection compared with ELISA and GC-MS following controlled cocaine administrationErin A Kolbrich
Chemistry and Drug Metabolism Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 5500 Nathan Shock Drive, Baltimore, Maryland 21224, USA
J Anal Toxicol 27:407-11. 2003..4%, 92.2%, and 90.7%, respectively. Cozart RapiScan had performance similar to the COC ELISA assay for the detection of cocaine exposure and suitable sensitivity and specificity at the proposed SAMHSA cutoffs...
A factor analysis of the Fagerström Test for Nicotine Dependence (FTND)Aleksandras Radzius
Intramural Research Program, National Institute on Drug Abuse National Institutes of Health Baltimore MD 21224, USA
Nicotine Tob Res 5:255-40. 2003..These two dimensions may provide indirect assessment of a smoker's daily nicotine intake. Testing this hypothesis requires correlation of biomarkers and responses to specific items of the FTND...
Tobacco Craving Questionnaire: reliability and validity of a new multifactorial instrumentStephen J Heishman
Clinical Pharmacology and Therapeutics Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore MD 21224, USA
Nicotine Tob Res 5:645-54. 2003..These preliminary data suggest that the TCQ is a reliable and valid instrument for assessing tobacco craving in individuals not attempting to reduce or quit smoking...
Sensory and physiologic effects of menthol and non-menthol cigarettes with differing nicotine deliveryWallace B Pickworth
Clinical Pharmacology Branch, National Institute on Drug Abuse, Intramural Research Program, Addiction Research Center, National Institutes of Health, PO Box 5180, Baltimore, MD 21224, USA
Pharmacol Biochem Behav 71:55-61. 2002..These results illustrate the importance of threshold levels of nicotine on subjective responses to cigarette smoking...
Clove cigarette smoking: biochemical, physiological, and subjective effectsJennifer L Malson
National Institute on Drug Abuse, Intramural Research Program, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
Pharmacol Biochem Behav 74:739-45. 2003..Taste satisfaction, aromatic odor, and novelty may contribute to their appeal to young smokers...
Urinary elimination of cocaine metabolites in chronic cocaine users during cessationKenzie L Preston
Clinical Pharmacology and Therapeutics Research Branch, Intramural Research Program, National Institute on Drug Abuse, Baltimore, Maryland 21224, USA
J Anal Toxicol 26:393-400. 2002....
Behavioral predictors of substance-use initiation in adolescents with and without attention-deficit/hyperactivity disorderMonique Ernst
Mood and Anxiety Disorders Program, National Institute of Mental Health, Bethesda, MD 20892 2670, USA
Pediatrics 117:2030-9. 2006..Our goal was to examine substance-use initiation in healthy adolescents and in adolescents who have been diagnosed with attention-deficit/hyperactivity disorder...
Effect of tobacco craving cues on memory encoding and retrieval in smokersStephen J Heishman
Clinical Pharmacology and Therapeutics Branch, National Institute on Drug Abuse, NIH, DHHS, Intramural Research Program, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
Addict Behav 31:1116-21. 2006..There was a trend toward impaired working memory following craving scripts compared with neutral scripts. These data support the hypothesis that the cognitive underpinnings of encoding and retrieval processes are distinct...
Blockade of effects of smoked marijuana by the CB1-selective cannabinoid receptor antagonist SR141716M A Huestis
National Institute on Drug Abuse Intramural Research Program, 5500 Nathan Shock Dr, Baltimore, MD 21224, USA
Arch Gen Psychiatry 58:322-8. 2001..These findings suggest that CB1 receptors mediate many of the effects of marijuana, but this has not been evaluated in humans...
Age at menarche and weight concerns in relation to smoking trajectory and dependence among adolescent girls enrolled in a smoking cessation trialMaria Jaszyna-Gasior
National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Department of Health and Human Services, Biomedical Research Center, Baltimore, Maryland 21224, USA
Addict Behav 34:92-5. 2009..Findings support previous research showing that early maturation represents a risk factor for substance use. Further study in larger samples that include non-treatment-seeking adolescent female smokers is warranted...
A link between adolescent nicotine metabolism and smoking topographyEric T Moolchan
National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, MD, USA
Cancer Epidemiol Biomarkers Prev 18:1578-83. 2009....
Progression to daily smoking: is there a gender difference among cessation treatment seekers?Elissa D Thorner
Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse Intramural Research Program, Baltimore, MD 21224, USA
Subst Use Misuse 42:829-35. 2007..Additional research is needed to explore the specific factors that differentially affect smoking trajectory in girls compared to boys...
Effect of tobacco deprivation on the attentional blink in rapid serial visual presentationAdrienne Heinz
Clinical Pharmacology and Therapeutics Branch, National Institute on Drug Abuse, NIH, Baltimore, Maryland 21224, USA
Hum Psychopharmacol 22:89-96. 2007..These results suggest that the AB is influenced by stimulus duration, but not by 12 h of tobacco deprivation...
Puffing behavior during the smoking of a single cigarette in tobacco-dependent adolescentsCharles C Collins
Nicotine Psychopharmacology Section, Intramural Research Program, National Institute on Drug Abuse, 251 Bayview Boulevard, Baltimore, MD 21224, USA
Nicotine Tob Res 12:164-7. 2010..The purpose of this study was to examine the pattern of puffing behavior during the smoking of a single cigarette in adolescents...
Opioid disposition in human sweat after controlled oral codeine administrationEugene W Schwilke
Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, NIH, Baltimore, MD 21224, USA
Clin Chem 52:1539-45. 2006..These results are consistent, considering the complex processes of codeine deposition in sweat. Sweat testing is a useful alternative technique for qualitative monitoring of opioid use...
Smoking topography and trajectory of asthmatic adolescents requesting cessation treatmentDarin M Zimmerman
Teen Tobacco Addiction Treatment Research Clinic, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, U.S. Department of Health and Human Services, Baltimore, MD 21224, USA
Prev Med 39:940-2. 2004..These findings highlight the need for more effective health counseling of asthmatic youth regarding the physical and behavioral effects of smoking...
History of marijuana use and tobacco smoking topography in tobacco-dependent adolescentsA Thiri Aung
Clinical Pharmacology and Treatment Research Branch, National Institutes of Health, National Institute on Drug Abuse, Intramural Research Program, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
Addict Behav 29:699-706. 2004..Our findings in adolescent smokers are consistent with results from adult studies in which history of MJ smoking was not associated with changes in tobacco smoking topography...
Urinary pharmacokinetics of 11-nor-9-carboxy-delta9-tetrahydrocannabinol after controlled oral delta9-tetrahydrocannabinol administrationRichard A Gustafson
Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, 5500 Nathan Shock Drive, Baltimore, Maryland 21224, USA
J Anal Toxicol 28:160-7. 2004..These controlled drug administration data should assist in the interpretation of urine cannabinoid results and provide clinicians with valuable information for future pharmacological studies...
Interest in marijuana treatment programs among teenage smokers and nonsmokersAmy J Sheer
National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD 21224, USA
J Subst Abuse Treat 37:421-5. 2009..These findings suggest that most adolescent marijuana smokers endorse the need for and are willing to attend marijuana treatment programs...
Sensitivity, specificity, and efficiency in detecting opiates in oral fluid with the Cozart Opiate Microplate EIA and GC-MS following controlled codeine administrationAllan J Barnes
Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland 21124, USA
J Anal Toxicol 27:402-7. 2003..In addition, the data, collected following controlled oral codeine administration, may aid in the interpretation of opiate oral fluid test results and in the selection of appropriate oral fluid screening and confirmation cutoffs...
Relative rates of AIDS among racial/ethnic groups by exposure categoriesH W Haverkos
National Institute of Drug Abuse, National Institutes of Health, Baltimore, Maryland, USA
J Natl Med Assoc 91:17-24. 1999....
African-American teen smokers: issues to consider for cessation treatmentE T Moolchan
National Institute of Health, National Institute on Drug Abuse Intramural Research Program, Teen Tobacco Addiction Treatment Research Clinic, Baltimore, MD, USA
J Natl Med Assoc 92:558-62. 2000..These observations also highlight the importance of ethnocultural issues in treatment research programs...
Nicotine delivery from smoking bidis and an additive-free cigaretteJennifer L Malson
Intramural Research Program, National Institute on Drug Abuse, Baltimore, Maryland 21224, USA
Nicotine Tob Res 4:485-90. 2002..These results do not support an emerging belief that bidi cigarettes are safer than conventional brands...
Simultaneous quantification of methamphetamine, cocaine, codeine, and metabolites in skin by positive chemical ionization gas chromatography-mass spectrometryWonkyung Yang
National Institute of Scientific Investigation, 331-1 Shinwol 7-Dong, Yangcheon-gu, Seoul 158-707, Republic of Korea
J Chromatogr B Analyt Technol Biomed Life Sci 833:210-8. 2006..999 and concentrations +/-20% of target. Intra- and inter-run precisions were <10%. This procedure should be useful for postmortem analysis; data are included on drug concentrations in skin after controlled drug administration...
Differences in risk-taking propensity across inner-city adolescent ever- and never-smokersC W Lejuez
Department of Psychlogy, University of Maryland, College Park, MD 20742, USA
Nicotine Tob Res 7:71-9. 2005..e., self-report measures and behavioral tasks) to identify adolescents' risk-taking susceptibilities and engagement in smoking and other risk-taking behaviors...
Performance characteristics of the Cozart RapiScan Oral Fluid Drug Testing System for opiates in comparison to ELISA and GC/MS following controlled codeine administrationSherri L Kacinko
Chemistry and Drug Metabolism Section, Intramural Research Program, NIDA, NIH, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
Forensic Sci Int 141:41-8. 2004....
Youth tobacco use: a global perspective for child health care cliniciansAlexander V Prokhorov
Department of Behavioral Science, University of Texas M D Anderson Cancer Center, Houston, Texas 77230 1439, USA
Pediatrics 118:e890-903. 2006..In addition, we provide a review of currently available funding opportunities for development and implementation of youth tobacco-control programs...
Gender differences in acute tobacco withdrawal: effects on subjective, cognitive, and physiological measuresAdam M Leventhal
Department of Behavioral Science, University of Texas M D Anderson Cancer Center, TX, USA
Exp Clin Psychopharmacol 15:21-36. 2007..10). These findings suggest that there are qualitative gender differences in the acute tobacco withdrawal syndrome that may underlie gender-specific smoking patterns...
Youth tobacco control research and activities in the United States: the current national landscapeJonathan P Winickoff
MGH Center for Child and Health Policy, Massachusetts General Hospital for Children, Boston, MA 02114, USA
Nicotine Tob Res 5:435-54. 2003..This synthesis of current research, funding sources, programmatic activities, and collaborations in the United States will be a valuable resource for clinicians, tobacco control advocates, researchers, and program planners...
Sex-based and hormonal contraception effects on the metabolism of nicotine among adolescent tobacco-dependent smokersIvan Berlin
Groupe Hospitalier Universitaire Pitié Salpêtrière, Universite Pierre et Marie Curie, Paris 6 and INSERM U 677, Paris, France
Nicotine Tob Res 9:493-8. 2007..Prospective controlled studies are needed to further evaluate the role of hormonal contraception in patterns of adolescent smoking and nicotine metabolism...
Associations between Cloninger's temperament dimensions and acute tobacco withdrawalAdam M Leventhal
Center for Alcohol and Addiction Studies, Brown University, Box G S121, Providence, RI 02912, USA
Addict Behav 32:2976-89. 2007..Smokers with different temperaments display different patterns of acute tobacco withdrawal, and may benefit from treatments matched to their particular abstinence profile...
Shorter time to first cigarette of the day in menthol adolescent cigarette smokersCharles C Collins
National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Department of Health and Human Services, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
Addict Behav 31:1460-4. 2006..Further study in a broader sample of adolescent smokers is warranted to elucidate the mechanisms underlying the effects of menthol smoking for youths...
