Research Topics
Species | Alison M MondulSummaryAffiliation: National Institutes of Health Country: USA Publications
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Publications
Genetic variation in the vitamin d pathway in relation to risk of prostate cancer--results from the breast and prostate cancer cohort consortiumAlison M Mondul
Corresponding Author Alison M Mondul, National Cancer Institute, NIH, 6120 Executive Blvd, Suite 320, Rockville, MD 20852
Cancer Epidemiol Biomarkers Prev 22:688-96. 2013..We examined prostate cancer risk in relation to single-nucleotide polymorphisms (SNP) in four genes shown to predict circulating levels of 25(OH)D...
Circulating thyroxine, thyroid-stimulating hormone, and hypothyroid status and the risk of prostate cancerAlison M Mondul
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
PLoS ONE 7:e47730. 2012..We undertook a prospective analysis of thyroid hormones and prostate cancer risk in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study...
Influence of vitamin D binding protein on the association between circulating vitamin D and risk of bladder cancerA M Mondul
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, Suite 320, Rockville, MD, USA
Br J Cancer 107:1589-94. 2012..There is little research investigating the role of vitamin D binding protein (DBP) in the association between 25-hydroxyvitamin D (25(OH)D) and disease risk...
Serum vitamin D and risk of bladder cancer in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening trialAlison M Mondul
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, MD, USA
Cancer Epidemiol Biomarkers Prev 21:1222-5. 2012....
Association of serum α-tocopherol with sex steroid hormones and interactions with smoking: implications for prostate cancer riskAlison M Mondul
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, MD, USA
Cancer Causes Control 22:827-36. 2011..The vitamin E-hormone relation is understudied in non-smokers...
Minimal detection bias in the inverse association between statin drug use and advanced prostate cancer risk: a simulation studyAlison M Mondul
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, United States
Cancer Epidemiol 35:e6-11. 2011..Detection bias arising from higher PSA screening rates among statin users vs. non-users could produce an inverse association for advanced disease. Thus, we conducted simulations to assess whether this source of bias is explanatory...
Serum total and HDL cholesterol and risk of prostate cancerAlison M Mondul
Department of Health and Human Services, Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 6120 Executive Blvd, Rockville, MD 20852, USA
Cancer Causes Control 22:1545-52. 2011..Confirmation in additional populations and examination of associations for lipoprotein subfractions are needed...
Supplementation with alpha-tocopherol or beta-carotene reduces serum concentrations of vascular endothelial growth factor-D, but Not -A or -C, in male smokersAlison M Mondul
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
J Nutr 141:2030-4. 2011..Although the mechanism through which these supplements affect cancer etiolog remains unclear, our results support the hypothesis that vitamin E and β-carotene may influence cancer progression through VEGF-mediated lymphangiogenesis...
Serum retinol and risk of prostate cancerAlison M Mondul
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
Am J Epidemiol 173:813-21. 2011..Future studies may clarify the underlying biologic mechanisms of the retinol-prostate cancer association...
Cigarette smoking and prostate cancer recurrence after prostatectomyCorinne E Joshu
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
J Natl Cancer Inst 103:835-8. 2011..31, 95% confidence interval = 1.05 to 5.10). This result suggests an association between cigarette smoking and risk of prostate cancer recurrence...
Serum vitamin D and risk of bladder cancerAlison M Mondul
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
Cancer Res 70:9218-23. 2010..03). In this prospective study of male smokers, lower serum 25(OH)D was associated with an increased risk of bladder cancer. Future studies should examine the association in other populations, especially nonsmokers and women...
Association of serum cholesterol and cholesterol-lowering drug use with serum sex steroid hormones in men in NHANES IIIAlison M Mondul
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Cancer Causes Control 21:1575-83. 2010..We evaluated whether serum testosterone and estradiol differ by cholesterol or cholesterol-lowering drug use...
Weight gain is associated with an increased risk of prostate cancer recurrence after prostatectomy in the PSA eraCorinne E Joshu
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe Street, Rm E6137, Baltimore, MD 21205, USA
Cancer Prev Res (Phila) 4:544-51. 2011..Physical activity (≥ 5 h/wk) did not attenuate risk in men who gained more than 2.2 kg. By avoiding weight gain, men with prostate cancer may both prevent recurrence and improve overall well-being...
Serum 25-hydroxy vitamin D and prostate cancer risk in a large nested case-control studyDemetrius Albanes
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Suite 320, Bethesda, MD 20982, USA
Cancer Epidemiol Biomarkers Prev 20:1850-60. 2011..Vitamin D compounds inhibit prostate tumorigenesis experimentally, but epidemiologic data are inconsistent with respect to prostate cancer risk, with some studies suggesting nonsignificant positive associations...
Decreased expression of Cyr61 is associated with prostate cancer recurrence after surgical treatmentKatherine B D'Antonio
Brady Urological Institute, Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
Clin Cancer Res 16:5908-13. 2010..In this study, we evaluated the association between Cyr61 staining intensity and subsequent recurrence after surgical treatment of clinically localized prostate cancer...
Association between plasma total cholesterol concentration and incident prostate cancer in the CLUE II cohortAlison M Mondul
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
Cancer Causes Control 21:61-8. 2010..Our study supports two prior ones suggesting that cholesterol influences risk of high-grade prostate cancer, and indirectly supports the hypothesis that cholesterol-lowering is a mechanism by which statins are protective...
Genome-wide association study of circulating retinol levelsAlison M Mondul
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Hum Mol Genet 20:4724-31. 2011..31× 10(-5)). Discovery of common genetic variants associated with serum retinol levels may provide further insight into the contribution of retinol and other vitamin A compounds to the development of cancer and other complex diseases...
Circulating 25-hydroxyvitamin D, vitamin D-binding protein and risk of prostate cancerStephanie J Weinstein
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD
Int J Cancer 132:2940-7. 2013..47, 95% CI: 0.98-2.20, p-trend 0.10, p-interaction = 0.02). Our data suggest that the primary vitamin D carrier protein, DBP, modulates the impact of vitamin D status on prostate cancer...
Body fatness and markers of thyroid function among U.S. men and womenCari M Kitahara
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America
PLoS ONE 7:e34979. 2012..S. population...
Statin drugs, serum cholesterol, and prostate-specific antigen in the National Health and Nutrition Examination Survey 2001-2004Alison M Mondul
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Cancer Causes Control 21:671-8. 2010..We evaluated the associations of statins and serum cholesterol with PSA to understand whether the inverse associations of statins and low cholesterol with aggressive prostate cancer are explained by detection bias...
Incidence and progression of lower urinary tract symptoms in a large prospective cohort of United States menElizabeth A Platz
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, The Brady Urological Institute, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA
J Urol 188:496-501. 2012....
Association of statin use with pathological tumor characteristics and prostate cancer recurrence after surgeryAlison M Mondul
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA
J Urol 185:1268-73. 2011..Thus, we evaluated the association of statin use with pathological tumor characteristics and prostate cancer recurrence after prostatectomy in a retrospective cohort...
Extracellular matrix associated protein CYR61 is linked to prostate cancer developmentKatherine B D'Antonio
The Brady Urological Institute, Baltimore, Maryland 21287, USA
J Urol 183:1604-10. 2010..Depending on cancer type these changes are linked with enhanced or inhibited tumor growth. We characterized Cyr61 in prostate cancer. Cyr61 is an integrin binding matricellular protein with altered expression in many cancer types...
A prospective study of lower urinary tract symptoms and erectile dysfunctionAlison M Mondul
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA
J Urol 179:2321-6. 2008..All except 1 of these studies were cross-sectional, limiting inferences about whether lower urinary tract symptoms precipitate erectile dysfunction...
