Dana N Mitzel

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Tick-borne flavivirus infection in Ixodes scapularis larvae: development of a novel method for synchronous viral infection of ticks
    Dana N Mitzel
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT 59840, USA
    Virology 365:410-8. 2007
  2. pmc Identification of genetic determinants of a tick-borne flavivirus associated with host-specific adaptation and pathogenicity
    Dana N Mitzel
    Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South Fourth Street, Hamilton, MT 59840, USA
    Virology 381:268-76. 2008
  3. pmc Tick-borne flaviviruses: dissecting host immune responses and virus countermeasures
    Shelly J Robertson
    Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 S 4th Street, Hamilton, MT 59840, USA
    Immunol Res 43:172-86. 2009
  4. pmc Differential salivary gland transcript expression profile in Ixodes scapularis nymphs upon feeding or flavivirus infection
    Kristin L McNally
    Laboratory of Virology, Rocky Mountain Laboratories, NIAID, NIH, 903 S Fourth St, Hamilton, MT 59840, USA
    Ticks Tick Borne Dis 3:18-26. 2012
  5. pmc Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist
    Sonja M Best
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT 59840, USA
    J Virol 79:12828-39. 2005
  6. pmc Chimeric tick-borne encephalitis/dengue virus is attenuated in Ixodes scapularis ticks and Aedes aegypti mosquitoes
    Amber R Engel
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Vector Borne Zoonotic Dis 11:665-74. 2011
  7. pmc Interferon regulatory factor 3 is a cellular partner of rotavirus NSP1
    Joel W Graff
    Veterinary Molecular Biology, Montana State University, Bozeman, Montana 59717, USA
    J Virol 76:9545-50. 2002
  8. ncbi request reprint Translational regulation of rotavirus gene expression
    Dana N Mitzel
    Veterinary Molecular Biology, PO Box 173610, Montana State University, Bozeman 59717 3610, USA
    J Gen Virol 84:383-91. 2003

Collaborators

Detail Information

Publications8

  1. pmc Tick-borne flavivirus infection in Ixodes scapularis larvae: development of a novel method for synchronous viral infection of ticks
    Dana N Mitzel
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT 59840, USA
    Virology 365:410-8. 2007
    ....
  2. pmc Identification of genetic determinants of a tick-borne flavivirus associated with host-specific adaptation and pathogenicity
    Dana N Mitzel
    Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South Fourth Street, Hamilton, MT 59840, USA
    Virology 381:268-76. 2008
    ..Thus, our data implicate a role for E, M, NS3, NS4A and NS4B in host adaptation and pathogenicity of tick-borne flaviviruses...
  3. pmc Tick-borne flaviviruses: dissecting host immune responses and virus countermeasures
    Shelly J Robertson
    Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 S 4th Street, Hamilton, MT 59840, USA
    Immunol Res 43:172-86. 2009
    ..This work will provide a more detailed understanding of early events in virus infection and their impact on flavivirus pathogenesis...
  4. pmc Differential salivary gland transcript expression profile in Ixodes scapularis nymphs upon feeding or flavivirus infection
    Kristin L McNally
    Laboratory of Virology, Rocky Mountain Laboratories, NIAID, NIH, 903 S Fourth St, Hamilton, MT 59840, USA
    Ticks Tick Borne Dis 3:18-26. 2012
    ..Further analysis of these transcripts may identify salivary factors that affect the transmission or replication of tick-borne flaviviruses...
  5. pmc Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist
    Sonja M Best
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT 59840, USA
    J Virol 79:12828-39. 2005
    ..Because NS5 may interfere with both innate and acquired immune responses to virus infection, this protein may have a significant role in viral pathogenesis...
  6. pmc Chimeric tick-borne encephalitis/dengue virus is attenuated in Ixodes scapularis ticks and Aedes aegypti mosquitoes
    Amber R Engel
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Vector Borne Zoonotic Dis 11:665-74. 2011
    ..The poor infectivity for both potential vectors reinforces the safety of chimeric virus-based vaccine candidates for the environment and for use in humans...
  7. pmc Interferon regulatory factor 3 is a cellular partner of rotavirus NSP1
    Joel W Graff
    Veterinary Molecular Biology, Montana State University, Bozeman, Montana 59717, USA
    J Virol 76:9545-50. 2002
    ..We predict that a role for NSP1 in rotavirus-infected cells is to inhibit activation of IRF-3 and diminish the cellular interferon response...
  8. ncbi request reprint Translational regulation of rotavirus gene expression
    Dana N Mitzel
    Veterinary Molecular Biology, PO Box 173610, Montana State University, Bozeman 59717 3610, USA
    J Gen Virol 84:383-91. 2003
    ..These data define a regulatory mechanism for the difference in amounts of VP6 and NSP1 and provide evidence for post-transcriptional control of rotavirus gene expression mediated by the translational efficiency of individual viral mRNAs...