Dana N Mitzel

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Tick-borne flavivirus infection in Ixodes scapularis larvae: development of a novel method for synchronous viral infection of ticks
    Dana N Mitzel
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT 59840, USA
    Virology 365:410-8. 2007
  2. pmc Identification of genetic determinants of a tick-borne flavivirus associated with host-specific adaptation and pathogenicity
    Dana N Mitzel
    Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South Fourth Street, Hamilton, MT 59840, USA
    Virology 381:268-76. 2008
  3. pmc Tick-borne flaviviruses: dissecting host immune responses and virus countermeasures
    Shelly J Robertson
    Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 S 4th Street, Hamilton, MT 59840, USA
    Immunol Res 43:172-86. 2009
  4. pmc Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist
    Sonja M Best
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT 59840, USA
    J Virol 79:12828-39. 2005
  5. pmc Chimeric tick-borne encephalitis/dengue virus is attenuated in Ixodes scapularis ticks and Aedes aegypti mosquitoes
    Amber R Engel
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Vector Borne Zoonotic Dis 11:665-74. 2011
  6. pmc Differential salivary gland transcript expression profile in Ixodes scapularis nymphs upon feeding or flavivirus infection
    Kristin L McNally
    Laboratory of Virology, Rocky Mountain Laboratories, NIAID, NIH, 903 S Fourth St, Hamilton, MT 59840, USA
    Ticks Tick Borne Dis 3:18-26. 2012
  7. pmc Interferon regulatory factor 3 is a cellular partner of rotavirus NSP1
    Joel W Graff
    Veterinary Molecular Biology, Montana State University, Bozeman, Montana 59717, USA
    J Virol 76:9545-50. 2002
  8. ncbi request reprint Translational regulation of rotavirus gene expression
    Dana N Mitzel
    Veterinary Molecular Biology, PO Box 173610, Montana State University, Bozeman 59717 3610, USA
    J Gen Virol 84:383-91. 2003

Collaborators

Detail Information

Publications8

  1. pmc Tick-borne flavivirus infection in Ixodes scapularis larvae: development of a novel method for synchronous viral infection of ticks
    Dana N Mitzel
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT 59840, USA
    Virology 365:410-8. 2007
    ....
  2. pmc Identification of genetic determinants of a tick-borne flavivirus associated with host-specific adaptation and pathogenicity
    Dana N Mitzel
    Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 South Fourth Street, Hamilton, MT 59840, USA
    Virology 381:268-76. 2008
    ..Thus, our data implicate a role for E, M, NS3, NS4A and NS4B in host adaptation and pathogenicity of tick-borne flaviviruses...
  3. pmc Tick-borne flaviviruses: dissecting host immune responses and virus countermeasures
    Shelly J Robertson
    Laboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 903 S 4th Street, Hamilton, MT 59840, USA
    Immunol Res 43:172-86. 2009
    ..This work will provide a more detailed understanding of early events in virus infection and their impact on flavivirus pathogenesis...
  4. pmc Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist
    Sonja M Best
    Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT 59840, USA
    J Virol 79:12828-39. 2005
    ..Because NS5 may interfere with both innate and acquired immune responses to virus infection, this protein may have a significant role in viral pathogenesis...
  5. pmc Chimeric tick-borne encephalitis/dengue virus is attenuated in Ixodes scapularis ticks and Aedes aegypti mosquitoes
    Amber R Engel
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Vector Borne Zoonotic Dis 11:665-74. 2011
    ..The poor infectivity for both potential vectors reinforces the safety of chimeric virus-based vaccine candidates for the environment and for use in humans...
  6. pmc Differential salivary gland transcript expression profile in Ixodes scapularis nymphs upon feeding or flavivirus infection
    Kristin L McNally
    Laboratory of Virology, Rocky Mountain Laboratories, NIAID, NIH, 903 S Fourth St, Hamilton, MT 59840, USA
    Ticks Tick Borne Dis 3:18-26. 2012
    ..Further analysis of these transcripts may identify salivary factors that affect the transmission or replication of tick-borne flaviviruses...
  7. pmc Interferon regulatory factor 3 is a cellular partner of rotavirus NSP1
    Joel W Graff
    Veterinary Molecular Biology, Montana State University, Bozeman, Montana 59717, USA
    J Virol 76:9545-50. 2002
    ..We predict that a role for NSP1 in rotavirus-infected cells is to inhibit activation of IRF-3 and diminish the cellular interferon response...
  8. ncbi request reprint Translational regulation of rotavirus gene expression
    Dana N Mitzel
    Veterinary Molecular Biology, PO Box 173610, Montana State University, Bozeman 59717 3610, USA
    J Gen Virol 84:383-91. 2003
    ..These data define a regulatory mechanism for the difference in amounts of VP6 and NSP1 and provide evidence for post-transcriptional control of rotavirus gene expression mediated by the translational efficiency of individual viral mRNAs...