Andreas Meyer-Lindenberg

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia
    Andreas Meyer-Lindenberg
    Unit on Integrative Neuroimaging, National Institute of Mental Health, National Institutes of Health, 10 4C101, 9000 Rockville Pike, Bethesda, Maryland 20892 1365, USA
    Nat Neurosci 5:267-71. 2002
  2. ncbi request reprint Evidence for abnormal cortical functional connectivity during working memory in schizophrenia
    A Meyer-Lindenberg
    Unit on Integrative Neuroimaging, Intramural Research Program, NIH, Bethesda, MD 20892 1365, USA
    Am J Psychiatry 158:1809-17. 2001
  3. ncbi request reprint Intermediate phenotypes and genetic mechanisms of psychiatric disorders
    Andreas Meyer-Lindenberg
    Unit for Systems Neuroscience in Psychiatry, Clinical Brain Disorders Branch, National Institute for Mental Health, National Institutes of Health, 9000 Rockville Pike, Bethesda, Maryland 20892, USA
    Nat Rev Neurosci 7:818-27. 2006
  4. pmc Neural mechanisms of genetic risk for impulsivity and violence in humans
    Andreas Meyer-Lindenberg
    Unit for Systems Neuroscience in Psychiatry, Neuroimaging Core Facility, National Institutes of Health, Department of Health and Human Services, 9000 Rockville Pike, Bethesda, MD 20892 1365, USA
    Proc Natl Acad Sci U S A 103:6269-74. 2006
  5. ncbi request reprint Neural correlates of genetically abnormal social cognition in Williams syndrome
    Andreas Meyer-Lindenberg
    Section on Integrative Neuroimaging, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Nat Neurosci 8:991-3. 2005
  6. ncbi request reprint Midbrain dopamine and prefrontal function in humans: interaction and modulation by COMT genotype
    Andreas Meyer-Lindenberg
    Section on Integrative Neuroimaging, National Institute for Mental Health, National Institutes of Health, Department of Health and Human Services, 9000 Rockville Pike, Bethesda, Maryland 20892 1365, USA
    Nat Neurosci 8:594-6. 2005
  7. ncbi request reprint Regionally specific disturbance of dorsolateral prefrontal-hippocampal functional connectivity in schizophrenia
    Andreas S Meyer-Lindenberg
    Unit on Integrative Neuroimaging, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 62:379-86. 2005
  8. pmc Functional, structural, and metabolic abnormalities of the hippocampal formation in Williams syndrome
    Andreas Meyer-Lindenberg
    Genes, Cognition, and Psychosis Program, National Institute of Mental Health, NIH, Department of Health and Human Services, Bethesda, MD 20892 1365, USA
    J Clin Invest 115:1888-95. 2005
  9. ncbi request reprint Impact of complex genetic variation in COMT on human brain function
    A Meyer-Lindenberg
    Unit for Systems Neuroscience in Psychiatry, National Institute of Mental Health, NIH, DHHS, Bethesda, MD 20892 1257, USA
    Mol Psychiatry 11:867-77, 797. 2006
  10. ncbi request reprint Neural basis of genetically determined visuospatial construction deficit in Williams syndrome
    Andreas Meyer-Lindenberg
    Unit on Integrative Neuroimaging, Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, 10 4C101, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Neuron 43:623-31. 2004

Collaborators

Detail Information

Publications55

  1. ncbi request reprint Reduced prefrontal activity predicts exaggerated striatal dopaminergic function in schizophrenia
    Andreas Meyer-Lindenberg
    Unit on Integrative Neuroimaging, National Institute of Mental Health, National Institutes of Health, 10 4C101, 9000 Rockville Pike, Bethesda, Maryland 20892 1365, USA
    Nat Neurosci 5:267-71. 2002
    ....
  2. ncbi request reprint Evidence for abnormal cortical functional connectivity during working memory in schizophrenia
    A Meyer-Lindenberg
    Unit on Integrative Neuroimaging, Intramural Research Program, NIH, Bethesda, MD 20892 1365, USA
    Am J Psychiatry 158:1809-17. 2001
    ..The authors applied to schizophrenia a recently available functional neuroimaging analytic method that permits characterization of cooperative action on the systems level...
  3. ncbi request reprint Intermediate phenotypes and genetic mechanisms of psychiatric disorders
    Andreas Meyer-Lindenberg
    Unit for Systems Neuroscience in Psychiatry, Clinical Brain Disorders Branch, National Institute for Mental Health, National Institutes of Health, 9000 Rockville Pike, Bethesda, Maryland 20892, USA
    Nat Rev Neurosci 7:818-27. 2006
    ..Using imaging genetics as an example, we illustrate recent advances, challenges and implications of linking genes to structural and functional variation in brain systems related to cognition and emotion...
  4. pmc Neural mechanisms of genetic risk for impulsivity and violence in humans
    Andreas Meyer-Lindenberg
    Unit for Systems Neuroscience in Psychiatry, Neuroimaging Core Facility, National Institutes of Health, Department of Health and Human Services, 9000 Rockville Pike, Bethesda, MD 20892 1365, USA
    Proc Natl Acad Sci U S A 103:6269-74. 2006
    ....
  5. ncbi request reprint Neural correlates of genetically abnormal social cognition in Williams syndrome
    Andreas Meyer-Lindenberg
    Section on Integrative Neuroimaging, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Nat Neurosci 8:991-3. 2005
    ..Activation and interactions of prefrontal regions linked to amygdala, especially orbitofrontal cortex, were abnormal, suggesting a genetically controlled neural circuitry for regulating human social behavior...
  6. ncbi request reprint Midbrain dopamine and prefrontal function in humans: interaction and modulation by COMT genotype
    Andreas Meyer-Lindenberg
    Section on Integrative Neuroimaging, National Institute for Mental Health, National Institutes of Health, Department of Health and Human Services, 9000 Rockville Pike, Bethesda, Maryland 20892 1365, USA
    Nat Neurosci 8:594-6. 2005
    ..These data implicate a dopaminergic tuning mechanism in prefrontal cortex and suggest a systems-level mechanism for cognitive and neuropsychiatric associations with COMT...
  7. ncbi request reprint Regionally specific disturbance of dorsolateral prefrontal-hippocampal functional connectivity in schizophrenia
    Andreas S Meyer-Lindenberg
    Unit on Integrative Neuroimaging, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 62:379-86. 2005
    ..It has been hypothesized that the pathophysiology of the disorder might involve an alteration of functional interactions between medial temporal and prefrontal areas...
  8. pmc Functional, structural, and metabolic abnormalities of the hippocampal formation in Williams syndrome
    Andreas Meyer-Lindenberg
    Genes, Cognition, and Psychosis Program, National Institute of Mental Health, NIH, Department of Health and Human Services, Bethesda, MD 20892 1365, USA
    J Clin Invest 115:1888-95. 2005
    ..These data demonstrate abnormalities in HF in WS in agreement with murine models, implicate LIMK1 and CYLN2 in human hippocampal function, and suggest that hippocampal dysfunction may contribute to neurocognitive abnormalities in WS...
  9. ncbi request reprint Impact of complex genetic variation in COMT on human brain function
    A Meyer-Lindenberg
    Unit for Systems Neuroscience in Psychiatry, National Institute of Mental Health, NIH, DHHS, Bethesda, MD 20892 1257, USA
    Mol Psychiatry 11:867-77, 797. 2006
    ..This work provides an in vivo approach to functional validation in brain of the biological impact of complex genetic variations within a gene that may be critical for its clinical association...
  10. ncbi request reprint Neural basis of genetically determined visuospatial construction deficit in Williams syndrome
    Andreas Meyer-Lindenberg
    Unit on Integrative Neuroimaging, Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, 10 4C101, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Neuron 43:623-31. 2004
    ....
  11. pmc Transitions between dynamical states of differing stability in the human brain
    Andreas Meyer-Lindenberg
    Clinical Brain Disorders Branch, National Institute of Mental Health, and Human Cortical Physiology Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 99:10948-53. 2002
    ....
  12. ncbi request reprint Catechol O-methyltransferase val158met genotype and neural mechanisms related to affective arousal and regulation
    Emily M Drabant
    Genes, Cognition, and Psychosis Program, Intramural Research Program, National Institute of Mental Health, National Institutes of Health DHHS, 10 Center Drive, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 63:1396-406. 2006
    ....
  13. pmc Evidence that altered amygdala activity in schizophrenia is related to clinical state and not genetic risk
    Roberta Rasetti
    Genes, Cognition, and Psychosis Program, IRP, NIMH, NIH, Rm 4S 235, 10 Center Dr, Bethesda, MD 20892, USA
    Am J Psychiatry 166:216-25. 2009
    ..The purpose of the present study was to examine amygdala response to threatening faces among healthy siblings of schizophrenia patients in whom a subtler heritable deficit might be observed...
  14. ncbi request reprint Heritability of brain morphology related to schizophrenia: a large-scale automated magnetic resonance imaging segmentation study
    Aaron L Goldman
    Neuroimaging Core Facility, Genes, Cognition and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    Biol Psychiatry 63:475-83. 2008
    ..Currently available data on the heritability of these structural changes are inconsistent...
  15. ncbi request reprint 5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression
    Lukas Pezawas
    Genes, Cognition and Psychosis Program, National Institute of Mental Health, National Institutes of Health, 10 Center Drive 4S235, Bethesda, Maryland 20892 1379, USA
    Nat Neurosci 8:828-34. 2005
    ....
  16. pmc Is gray matter volume an intermediate phenotype for schizophrenia? A voxel-based morphometry study of patients with schizophrenia and their healthy siblings
    Robyn A Honea
    Genes, Cognition and Psychosis Program, National Institute of Mental Health, Division of Intramural Research, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1364, USA
    Biol Psychiatry 63:465-74. 2008
    ..We sought to discover previously unidentified gray matter volume differences in patients with schizophrenia and their siblings with optimized voxel-based morphometry...
  17. ncbi request reprint Allelic variation in RGS4 impacts functional and structural connectivity in the human brain
    Joshua W Buckholtz
    Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 1364, USA
    J Neurosci 27:1584-93. 2007
    ..These findings suggest mechanisms in brain for the association of RGS4 with risk for psychiatric illness...
  18. pmc Abnormalities in neural processing of emotional stimuli in Williams syndrome vary according to social vs. non-social content
    Karen E Munoz
    Section on Integrative Neuroimaging, National Institute of Mental Health, NIH, DHHS, Bethesda, MD 20892, USA
    Neuroimage 50:340-6. 2010
    ..These data provide further evidence of disruption in amygdala-prefrontal circuitry in individuals with WS...
  19. pmc Catechol-o-methyltransferase valine(158)methionine genotype and resting regional cerebral blood flow in medication-free patients with schizophrenia
    Daniel Paul Eisenberg
    Section on Integrative Neuroimaging, National Institute of Mental Health, National Institutes of Health NIH, Department of Health and Human Services DHHS, Bethesda, Maryland 20892 1365, USA
    Biol Psychiatry 67:287-90. 2010
    ..Task-independent effects of this polymorphism in schizophrenia have not yet been characterized...
  20. ncbi request reprint The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology
    Lukas Pezawas
    Genes, Cognition, and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 1379, USA
    J Neurosci 24:10099-102. 2004
    ....
  21. ncbi request reprint Catechol-O-methyltransferase Val158Met modulation of prefrontal-parietal-striatal brain systems during arithmetic and temporal transformations in working memory
    Hao Yang Tan
    Clinical Brain Disorders Branch, Genes Cognition and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 27:13393-401. 2007
    ..These findings add to the integration of dopaminergic signaling in basic cortical assemblies with their roles in specific human brain networks during the orchestration of information processing in WM...
  22. pmc Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia
    Joseph H Callicott
    Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, Division of Intramural Research, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 102:8627-32. 2005
    ....
  23. pmc A genetic model for understanding higher order visual processing: functional interactions of the ventral visual stream in Williams syndrome
    Deepak Sarpal
    Section on Integrative Neuroimaging, Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, National Institute of Mental Health, NIH, DHHS, Bethesda, MD 20892, USA
    Cereb Cortex 18:2402-9. 2008
    ....
  24. pmc Genetic variation in AKT1 is linked to dopamine-associated prefrontal cortical structure and function in humans
    Hao Yang Tan
    Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, Division of Intramural Research Programs, National Institute of Mental Health, NIH, Bethesda, Maryland 20892, USA
    J Clin Invest 118:2200-8. 2008
    ..These data implicate AKT1 in modulating human prefrontal-striatal structure and function and suggest that the mechanism of this effect may be coupled to dopaminergic signaling and relevant to the expression of psychosis...
  25. pmc Know your place: neural processing of social hierarchy in humans
    Caroline F Zink
    Unit for Systems Neuroscience in Psychiatry, Genes, Cognition, and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Neuron 58:273-83. 2008
    ..Our results identify neural mechanisms that may mediate the enormous influence of social status on human behavior and health...
  26. pmc Vasopressin modulates medial prefrontal cortex-amygdala circuitry during emotion processing in humans
    Caroline F Zink
    Genes, Cognition, and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    J Neurosci 30:7017-22. 2010
    ....
  27. ncbi request reprint Interindividual differences in functional interactions among prefrontal, parietal and parahippocampal regions during working memory
    Michael F Glabus
    Unit on Integrative Neuroimaging, National Institutes of Health, Department of Health and Human Services, 9000 Rockville Pike, Bethesda, MD, 20892 1365, USA
    Cereb Cortex 13:1352-61. 2003
    ..These results demonstrate that individual behavioral characteristics are reflected in specific neurofunctional patterns at the system level and that these can be captured by analytical techniques such as SEM...
  28. pmc Epistasis between catechol-O-methyltransferase and type II metabotropic glutamate receptor 3 genes on working memory brain function
    Hao Yang Tan
    Genes, Cognition, and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health Intramural Research Program, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 104:12536-41. 2007
    ..These findings extend putative brain dopaminergic and glutamatergic relationships indexed by COMT and GRM3 to a systems-level interaction in human cortical circuits implicated in working memory dysfunction such as in schizophrenia...
  29. pmc Genetic evidence implicating DARPP-32 in human frontostriatal structure, function, and cognition
    Andreas Meyer-Lindenberg
    Unit for Systems Neuroscience in Psychiatry, Neuroimaging Core Facility, and Clinical Brain Disorders Branch, Genes, Cognition, and Psychosis Program, National Institute for Mental Health NIMH, NIH, Bethesda, MD 20892, USA
    J Clin Invest 117:672-82. 2007
    ..Our convergent results identify a prefrontal-neostriatal system affected by variation in PPP1R1B and suggest that DARPP-32 plays a pivotal role in cognitive function and possibly in the pathogenesis of schizophrenia...
  30. pmc Impact of interacting functional variants in COMT on regional gray matter volume in human brain
    Robyn Honea
    Genes, Cognition and Psychosis Program, National Institute of Mental Health, Division of Intramural Research, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Neuroimage 45:44-51. 2009
    ....
  31. ncbi request reprint Neurophysiological correlates of age-related changes in working memory capacity
    Venkata S Mattay
    Clinical Brain Disorders Branch, Genes, Cognition and Psychosis Program, National Institute of Mental Health, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Neurosci Lett 392:32-7. 2006
    ..As cognitive demand increases, however, they are pushed past a threshold beyond which physiological compensation cannot be made and, a decline in performance occurs...
  32. pmc Retinotopically defined primary visual cortex in Williams syndrome
    Rosanna K Olsen
    Section on Integrative Neuroimaging, Clinical Brain Disorders Branch, National Institute of Mental Health, NIH, DHHS, Bethesda, MD 20892 1365, USA
    Brain 132:635-44. 2009
    ....
  33. pmc Investigation of anatomical thalamo-cortical connectivity and FMRI activation in schizophrenia
    Stefano Marenco
    Clinical Brain Disorders Branch, Genes, Cognition, and Psychosis Program, National Institute of Mental Health Intramural Research Program, Bethesda, MD, USA
    Neuropsychopharmacology 37:499-507. 2012
    ..These results suggest that thalamocortical connectivity to the LPFC is altered in schizophrenia with functional consequences on working memory processing in LPFC...
  34. pmc Hierarchical organization of human cortical networks in health and schizophrenia
    Danielle S Bassett
    Clinical Brain Disorders Branch, Genes Cognition and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 28:9239-48. 2008
    ....
  35. pmc A common allele in the oxytocin receptor gene (OXTR) impacts prosocial temperament and human hypothalamic-limbic structure and function
    Heike Tost
    Clinical Brain Disorders Branch, Genes, Cognition, and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 107:13936-41. 2010
    ..Our findings identify sex-dependent mechanisms impacting the structure and function of hypothalamic-limbic circuits that are of potential clinical and translational significance...
  36. pmc Age-related alterations in simple declarative memory and the effect of negative stimulus valence
    Vishnu P Murty
    National Institutes of Health, Bethesda, MD, USA
    J Cogn Neurosci 21:1920-33. 2009
    ....
  37. pmc The Williams syndrome chromosome 7q11.23 hemideletion confers hypersocial, anxious personality coupled with altered insula structure and function
    Mbemba Jabbi
    Section on Integrative Neuroimaging, National Institute of Mental Health, Intramural Research Program, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 109:E860-6. 2012
    ....
  38. ncbi request reprint Dysfunctional prefrontal regional specialization and compensation in schizophrenia
    Hao Yang Tan
    Unit on Functional MRI, Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, 10 Center Dr, Rm 4C 216, MSC 1364, Bethesda, MD 20892 1364, USA
    Am J Psychiatry 163:1969-77. 2006
    ....
  39. pmc Widespread reductions of cortical thickness in schizophrenia and spectrum disorders and evidence of heritability
    Aaron L Goldman
    Neuroimaging Core Facility, Genes, Cognition, and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892, USA
    Arch Gen Psychiatry 66:467-77. 2009
    ..To our knowledge, cortical thickness, a measure of particular interest in schizophrenia, has not previously been evaluated in terms of its heritability in relationship to risk for schizophrenia...
  40. pmc Normal age-related brain morphometric changes: nonuniformity across cortical thickness, surface area and gray matter volume?
    Herve Lemaitre
    Clinical Brain Disorder Branch, Gene Cognition and Psychosis program, NIH NIMH, Bethesda, MD 20892, USA
    Neurobiol Aging 33:617.e1-9. 2012
    ....
  41. pmc Functional polymorphisms in PRODH are associated with risk and protection for schizophrenia and fronto-striatal structure and function
    Lucas Kempf
    Department of Health and Human Services, Unit of Systems Neuroscience in Psychiatry, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Genet 4:e1000252. 2008
    ..Our findings suggest a role for functional genetic variation in POX on neostriatal-frontal circuits mediating risk and protection for schizophrenia...
  42. ncbi request reprint Shared and distinct neurophysiological components of the digits forward and backward tasks as revealed by functional neuroimaging
    Brooke K Gerton
    Unit on Integrative Neuroimaging, Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, NIH, Bethesda, MD 20892 1365, USA
    Neuropsychologia 42:1781-7. 2004
    ....
  43. ncbi request reprint Genetic contributions to human gyrification: sulcal morphometry in Williams syndrome
    J Shane Kippenhan
    National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    J Neurosci 25:7840-6. 2005
    ....
  44. ncbi request reprint Clinical and positron emission tomography of Parkinson's disease caused by LRRK2
    Dena G Hernandez
    Molecular Genetics Unit, National Institute on Aging, National Institutes of Health, Department of Health and Human Services, Porter Neuroscience Research Center, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Ann Neurol 57:453-6. 2005
    ....
  45. pmc Cognitive fitness of cost-efficient brain functional networks
    Danielle S Bassett
    Genes Cognition and Psychosis Program, Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 106:11747-52. 2009
    ..More generally, they echo the saying that "less is more": The information processing performance of a network can be enhanced by a sparse or low-cost configuration with disproportionately high efficiency...
  46. pmc Genetic contributions to white matter architecture revealed by diffusion tensor imaging in Williams syndrome
    Stefano Marenco
    Clinical Brain Disorders Branch, Genes Cognition and Psychosis Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 104:15117-22. 2007
    ....
  47. ncbi request reprint A validated network of effective amygdala connectivity
    Jason L Stein
    Unit for Systems Neuroscience in Psychiatry, Bethesda, MD 20892 1257, USA
    Neuroimage 36:736-45. 2007
    ..This validated model can be used to study neurocognitive correlates as well as genotype or disease-related alterations of functional interactions in the limbic system...
  48. pmc Age-related changes in midbrain dopaminergic regulation of the human reward system
    Jean Claude Dreher
    Section on Integrative Neuroimaging, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 105:15106-11. 2008
    ....
  49. pmc Enuresis as a premorbid developmental marker of schizophrenia
    Thomas M Hyde
    Clinical Brain Disorders Branch, NIMH DIRP NIH, Bethesda, MD 20892, USA
    Brain 131:2489-98. 2008
    ..These findings add to the evidence implicating prefrontal dysmaturation in this disorder, potentially related to genetic risk factors...
  50. ncbi request reprint Neural mechanisms in Williams syndrome: a unique window to genetic influences on cognition and behaviour
    Andreas Meyer-Lindenberg
    Unit for Systems Neuroscience in Psychiatry, National Institute of Mental Health, NIH, DHHS, 9000 Rockville Pike, Bethesda, Maryland 20892 1365, USA
    Nat Rev Neurosci 7:380-93. 2006
    ....
  51. doi request reprint False positives in imaging genetics
    Andreas Meyer-Lindenberg
    Unit for Systems Neuroscience in Psychiatry, National Institute for Mental Health, NIH, DHHS, 9000 Rockville Pike, Bethesda, MD 20892 1365, USA
    Neuroimage 40:655-61. 2008
    ..In fact, our observations indicate that these statistical thresholds are conservative...
  52. pmc A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia
    Stephen J Huffaker
    Clinical Brain Disorders Branch, National Institute of Mental Health, Bethesda, Maryland, USA
    Nat Med 15:509-18. 2009
    ..These results identify a previously undescribed KCNH2 channel isoform involved in cortical physiology, cognition and psychosis, providing a potential new therapeutic drug target...
  53. pmc Human neuroimaging of oxytocin and vasopressin in social cognition
    Caroline F Zink
    Genes, Cognition, and Psychosis Program, NIMH, NIH, DHHS, Bethesda, MD 20892, USA
    Horm Behav 61:400-9. 2012
    ..This article is part of a Special Issue entitled Oxytocin, Vasopressin, and Social Behavior...
  54. ncbi request reprint Imaging genetics for neuropsychiatric disorders
    Andreas Meyer-Lindenberg
    Unit for Systems Neuroscience in Psychiatry, Bethesda, MD 20892, USA
    Child Adolesc Psychiatr Clin N Am 16:581-97. 2007
    ..These data provide convergent evidence for neural circuitry mediating emotional regulation and social cognition under genetic control in humans...
  55. pmc Dopamine and psychosis: theory, pathomechanisms and intermediate phenotypes
    Heike Tost
    Unit for Systems Neuroscience in Psychiatry, National Institute of Mental Health, NIH, DHHS, 9000 Rockville Pike, Bethesda, MD 20892 1365, USA
    Neurosci Biobehav Rev 34:689-700. 2010
    ..This paper discusses the pathophysiological concepts, molecular mechanisms and neuroimaging evidence that link psychosis to disturbances in dopamine neurotransmission...