E Meshorer

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Alternative splicing and neuritic mRNA translocation under long-term neuronal hypersensitivity
    Eran Meshorer
    Department of Biological Chemistry, The Institute of Life Sciences and The Eric Roland Center for Neurodegenerative Diseases, The Hebrew University of Jerusalem, Israel 91904
    Science 295:508-12. 2002
  2. ncbi Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells
    Eran Meshorer
    National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Dev Cell 10:105-16. 2006
  3. ncbi Chromatin in pluripotent embryonic stem cells and differentiation
    Eran Meshorer
    National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Nat Rev Mol Cell Biol 7:540-6. 2006
  4. ncbi Chromatin in embryonic stem cell neuronal differentiation
    E Meshorer
    National Cancer Institute, NIH, Bethesda, MD 20852, USA
    Histol Histopathol 22:311-9. 2007
  5. ncbi Virtues and woes of AChE alternative splicing in stress-related neuropathologies
    Eran Meshorer
    National Cancer Institute, National Institutes of Health, Building 41, 41 Library Drive, Bethesda, MD 20892, USA
    Trends Neurosci 29:216-24. 2006
  6. ncbi SC35 promotes sustainable stress-induced alternative splicing of neuronal acetylcholinesterase mRNA
    E Meshorer
    Department of Biological Chemistry, The Hebrew University of Jerusalem, Jerusalem, Israel
    Mol Psychiatry 10:985-97. 2005
  7. ncbi Muscarinic modulations of neuronal anticholinesterase responses
    A Salmon
    Department of Biological Chemistry and The Eric Roland Center for Neurodegenerative Diseases, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
    Chem Biol Interact 157:105-13. 2005
  8. ncbi Combinatorial complexity of 5' alternative acetylcholinesterase transcripts and protein products
    Eran Meshorer
    Department of Biological Chemistry and the Israel Center of Neuronal Computation, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
    J Biol Chem 279:29740-51. 2004
  9. ncbi Splicing misplaced
    Eran Meshorer
    National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Cell 122:317-8. 2005
  10. ncbi Transcriptional competence in pluripotency
    Edupuganti V S Raghu Ram
    Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
    Genes Dev 23:2793-8. 2009

Collaborators

Detail Information

Publications19

  1. ncbi Alternative splicing and neuritic mRNA translocation under long-term neuronal hypersensitivity
    Eran Meshorer
    Department of Biological Chemistry, The Institute of Life Sciences and The Eric Roland Center for Neurodegenerative Diseases, The Hebrew University of Jerusalem, Israel 91904
    Science 295:508-12. 2002
    ..Our findings suggest that neuronal hypersensitivity under stress involves neuritic replacement of AChE-S with AChE-R...
  2. ncbi Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells
    Eran Meshorer
    National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Dev Cell 10:105-16. 2006
    ....
  3. ncbi Chromatin in pluripotent embryonic stem cells and differentiation
    Eran Meshorer
    National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Nat Rev Mol Cell Biol 7:540-6. 2006
    ..We discuss how unique properties of chromatin in ES cells contribute to the maintenance of pluripotency and the determination of differentiation properties...
  4. ncbi Chromatin in embryonic stem cell neuronal differentiation
    E Meshorer
    National Cancer Institute, NIH, Bethesda, MD 20852, USA
    Histol Histopathol 22:311-9. 2007
    ..Here I describe the changes in chromatin that accompany neuronal differentiation, particularly of embryonic stem cells, and discuss how chromatin serves as the master regulator of cellular destiny...
  5. ncbi Virtues and woes of AChE alternative splicing in stress-related neuropathologies
    Eran Meshorer
    National Cancer Institute, National Institutes of Health, Building 41, 41 Library Drive, Bethesda, MD 20892, USA
    Trends Neurosci 29:216-24. 2006
    ..g. Alzheimer's and Parkinson's diseases) and neuromuscular syndromes (e.g. myasthenia gravis) raises the possibility that future therapeutic drugs might target specific AChE variant(s) or the corresponding RNA transcripts...
  6. ncbi SC35 promotes sustainable stress-induced alternative splicing of neuronal acetylcholinesterase mRNA
    E Meshorer
    Department of Biological Chemistry, The Hebrew University of Jerusalem, Jerusalem, Israel
    Mol Psychiatry 10:985-97. 2005
    ..Together, these findings point to an interactive relationship of SC35 with cholinergic signals in the long-lasting consequences of stress on nervous system plasticity and development...
  7. ncbi Muscarinic modulations of neuronal anticholinesterase responses
    A Salmon
    Department of Biological Chemistry and The Eric Roland Center for Neurodegenerative Diseases, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
    Chem Biol Interact 157:105-13. 2005
    ....
  8. ncbi Combinatorial complexity of 5' alternative acetylcholinesterase transcripts and protein products
    Eran Meshorer
    Department of Biological Chemistry and the Israel Center of Neuronal Computation, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
    J Biol Chem 279:29740-51. 2004
    ..Alternative promoter usage combined with alternative splicing may thus lead to stress-dependent combinatorial complexity of AChE mRNA transcripts and their protein products...
  9. ncbi Splicing misplaced
    Eran Meshorer
    National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Cell 122:317-8. 2005
    ..In this issue of Cell, Denis et al. (2005) now report the presence of functional spliceosomes and signal-dependent pre-mRNA splicing in the cytoplasm of platelets...
  10. ncbi Transcriptional competence in pluripotency
    Edupuganti V S Raghu Ram
    Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
    Genes Dev 23:2793-8. 2009
    ....
  11. ncbi Chromatin and nuclear architecture in the nervous system
    Takumi Takizawa
    National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Trends Neurosci 31:343-52. 2008
    ....
  12. ncbi Global transcription in pluripotent embryonic stem cells
    Sol Efroni
    National Cancer Institute Center for Bioinformatics, National Institutes of Health, Rockville, MD 20852, USA
    Cell Stem Cell 2:437-47. 2008
    ..We propose that global transcription is a hallmark of pluripotent ESCs, contributing to their plasticity, and that lineage specification is driven by reduction of the transcribed portion of the genome...
  13. ncbi Pre-mRNA splicing modulations in senescence
    Eran Meshorer
    Department of Biological Chemistry, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
    Aging Cell 1:10-6. 2002
    ..Here, we review the potential genomic and environmental origins of such changes and discuss the research implications of these findings...
  14. ncbi Nuclear lamins: key regulators of nuclear structure and activities
    Miron Prokocimer
    Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Israel
    J Cell Mol Med 13:1059-85. 2009
    ..This review concentrates mainly on lamins, their structure and their roles in DNA replication, chromatin organization, adult stem cell differentiation, aging, tumorogenesis and the lamin mutations leading to laminopathic diseases...
  15. ncbi Chronic cholinergic imbalances promote brain diffusion and transport abnormalities
    Eran Meshorer
    Department of Biological Chemistry and Israel Center for Neuronal Computation, The Hebrew University of Jerusalem, Jerusalem, Israel
    FASEB J 19:910-22. 2005
    ....
  16. ncbi Chromatin plasticity and genome organization in pluripotent embryonic stem cells
    Anna Mattout
    Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel
    Curr Opin Cell Biol 22:334-41. 2010
    ..Plasticity thus seems to be supported more by different mechanisms maintaining an open chromatin state and less by regulating the location of genomic regions...
  17. ncbi Chromatin plasticity in pluripotent cells
    Shai Melcer
    Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel
    Essays Biochem 48:245-62. 2010
    ....
  18. ncbi Rejuvenating premature aging
    Eran Meshorer
    Nat Med 14:713-5. 2008
  19. ncbi Eran Meshorer: getting a chromatin perspective. [Interview by Caitlin Sedwick]
    Eran Meshorer
    Hebrew University, Israel
    J Cell Biol 182:618-9. 2008