Maria J Merino

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint The morphologic spectrum of kidney tumors in hereditary leiomyomatosis and renal cell carcinoma (HLRCC) syndrome
    Maria J Merino
    Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
    Am J Surg Pathol 31:1578-85. 2007
  2. pmc Protein expression profiling in the spectrum of renal cell carcinomas
    Vladimir A Valera
    1 Surgical Pathology Section, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, USA
    J Cancer 1:184-96. 2010
  3. pmc Comprehensive microRNA Profiling of Prostate Cancer
    Beatriz A Walter
    1 Translational Surgical Pathology Section, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, USA
    J Cancer 4:350-7. 2013
  4. pmc miR-21 Expression in Pregnancy-Associated Breast Cancer: A Possible Marker of Poor Prognosis
    Beatriz A Walter
    1 Laboratory of Pathology, National Institutes of Health, National Cancer Institute, Bethesda, MD, USA
    J Cancer 2:67-75. 2011
  5. pmc Regulatory Effects of microRNA-92 (miR-92) on VHL Gene Expression and the Hypoxic Activation of miR-210 in Clear Cell Renal Cell Carcinoma
    Vladimir A Valera
    1 Translational Surgical Pathology Section, Laboratory of Pathology
    J Cancer 2:515-26. 2011
  6. pmc A possible new syndrome with growth-hormone secreting pituitary adenoma, colonic polyposis, lipomatosis, lentigines and renal carcinoma in association with familial testicular germ cell malignancy: A case report
    Phuong L Mai
    Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    J Med Case Reports 1:9. 2007
  7. pmc UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer
    Youfeng Yang
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1107, Bldg 10 CRC, Room 1 5942, Bethesda, MD 20892 1107
    Cancer Genet Cytogenet 196:45-55. 2010
  8. ncbi request reprint High frequency of somatic frameshift BHD gene mutations in Birt-Hogg-Dubé-associated renal tumors
    Cathy D Vocke
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
    J Natl Cancer Inst 97:931-5. 2005
  9. pmc Defining early-onset kidney cancer: implications for germline and somatic mutation testing and clinical management
    Brian Shuch
    All authors Center for Cancer Research, National Cancer Institute, Bethesda, MD
    J Clin Oncol 32:431-7. 2014
  10. pmc Effect of lapatinib on the outgrowth of metastatic breast cancer cells to the brain
    Brunilde Gril
    Women s Cancers Section, Laboratory of Molecular Pharmacology, National Cancer Institute, National Institutes of Health, 9000 Rockville Pike, Building 37, Room 1122, MSC 4254, Bethesda, MD 20892, USA
    J Natl Cancer Inst 100:1092-103. 2008

Detail Information

Publications118 found, 100 shown here

  1. ncbi request reprint The morphologic spectrum of kidney tumors in hereditary leiomyomatosis and renal cell carcinoma (HLRCC) syndrome
    Maria J Merino
    Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
    Am J Surg Pathol 31:1578-85. 2007
    ..At the moment, morphology is the best tool to recognize these tumors. Proper diagnosis of this syndrome by the pathologist may assist in early detection of these tumors...
  2. pmc Protein expression profiling in the spectrum of renal cell carcinomas
    Vladimir A Valera
    1 Surgical Pathology Section, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, USA
    J Cancer 1:184-96. 2010
    ..From these changes, Hsp27 and TPI-1 emerged as potential candidates for the differentiation and prognosis in RCC...
  3. pmc Comprehensive microRNA Profiling of Prostate Cancer
    Beatriz A Walter
    1 Translational Surgical Pathology Section, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, USA
    J Cancer 4:350-7. 2013
    ..These differential expressed miRNAs may provide novel diagnostic and prognostic tools that will assist in the recognition of prostate cancers with aggressive behavior...
  4. pmc miR-21 Expression in Pregnancy-Associated Breast Cancer: A Possible Marker of Poor Prognosis
    Beatriz A Walter
    1 Laboratory of Pathology, National Institutes of Health, National Cancer Institute, Bethesda, MD, USA
    J Cancer 2:67-75. 2011
    ..Conclusion: Our study supports the involvement of miR-21 in breast cancer progression and metastasis formation in PABC implying a role of this miRNA as a marker for poor prognosis in PABC patients...
  5. pmc Regulatory Effects of microRNA-92 (miR-92) on VHL Gene Expression and the Hypoxic Activation of miR-210 in Clear Cell Renal Cell Carcinoma
    Vladimir A Valera
    1 Translational Surgical Pathology Section, Laboratory of Pathology
    J Cancer 2:515-26. 2011
    ..Our data show consistent disregulation of miRNAs in human kidney cancer, some of which are potentially involved in critical gene silencing in RCC and others that are activated as part of the pathophysiological response in these tumors...
  6. pmc A possible new syndrome with growth-hormone secreting pituitary adenoma, colonic polyposis, lipomatosis, lentigines and renal carcinoma in association with familial testicular germ cell malignancy: A case report
    Phuong L Mai
    Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    J Med Case Reports 1:9. 2007
    ..Familial testicular cancer in the presence of other findings in affected and unaffected family members might indicate a previously-unidentified hereditary cancer syndrome...
  7. pmc UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer
    Youfeng Yang
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1107, Bldg 10 CRC, Room 1 5942, Bethesda, MD 20892 1107
    Cancer Genet Cytogenet 196:45-55. 2010
    ..This tumor model is the embodiment of the Warburg effect. UOK 262 provides a unique in vitro and in vivo preclinical model for studying the bioenergetics of the Warburg effect in human cancer...
  8. ncbi request reprint High frequency of somatic frameshift BHD gene mutations in Birt-Hogg-Dubé-associated renal tumors
    Cathy D Vocke
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
    J Natl Cancer Inst 97:931-5. 2005
    ..These results support a role for BHD as a tumor suppressor gene that predisposes to the development of renal tumors when both copies are inactivated...
  9. pmc Defining early-onset kidney cancer: implications for germline and somatic mutation testing and clinical management
    Brian Shuch
    All authors Center for Cancer Research, National Cancer Institute, Bethesda, MD
    J Clin Oncol 32:431-7. 2014
    ..No guidelines exist for patient selection for RCC germline mutation testing. We evaluate how age of onset could indicate the need for germline mutation testing for detection of inherited forms of kidney cancer...
  10. pmc Effect of lapatinib on the outgrowth of metastatic breast cancer cells to the brain
    Brunilde Gril
    Women s Cancers Section, Laboratory of Molecular Pharmacology, National Cancer Institute, National Institutes of Health, 9000 Rockville Pike, Building 37, Room 1122, MSC 4254, Bethesda, MD 20892, USA
    J Natl Cancer Inst 100:1092-103. 2008
    ..We examined the efficacy of lapatinib, an inhibitor of the epidermal growth factor receptor (EGFR) and HER2 kinases, for preventing the outgrowth of breast cancer cells in the brain in a mouse xenograft model of brain metastasis...
  11. pmc Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-beta signaling
    Seung Beom Hong
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, 10 Center Drive MSC1107, 10 CRC 1W 5940, Bethesda, MD 20892, USA
    Mol Cancer 9:160. 2010
    ..Somatic mutations or loss of heterozygosity in the remaining wild type copy of the FLCN gene have been found in renal tumors from BHD patients suggesting that FLCN is a classic tumor suppressor gene...
  12. pmc Germline BHD-mutation spectrum and phenotype analysis of a large cohort of families with Birt-Hogg-Dubé syndrome
    Laura S Schmidt
    Basic Research Program, Science Applications International Corporation Frederick Inc, Frederick, MD, USA
    Am J Hum Genet 76:1023-33. 2005
    ..This study expands the BHD-mutation spectrum and evaluates genotype-phenotype correlations among families with BHD...
  13. ncbi request reprint Proteomic identification of new biomarkers and application in thyroid cytology
    Carlos Torres-Cabala
    Surgical Pathology Section, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA 20892, USA
    Acta Cytol 50:518-28. 2006
    ..To validate proteins identified by proteomics as potentially usable markers in thyroid pathology...
  14. pmc The UOK 257 cell line: a novel model for studies of the human Birt-Hogg-Dubé gene pathway
    Youfeng Yang
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 10, Room 1W 5888, Bethesda, MD 20892, USA
    Cancer Genet Cytogenet 180:100-9. 2008
    ..The result demonstrates that the established tumor cells consist of two cell populations, one containing four and one containing five copies of the MYC oncogene...
  15. pmc Morphologic and molecular characteristics of uterine leiomyomas in hereditary leiomyomatosis and renal cancer (HLRCC) syndrome
    Julian Sanz-Ortega
    Translational Surgical Pathology, National Institutes of Health, Bethesda, MD 20892, USA
    Am J Surg Pathol 37:74-80. 2013
    ..The specific morphologic features of the uterine leiomyomas that we describe may help in the identification of patients who may be part of the hereditary syndrome...
  16. pmc Prostate cancer: can multiparametric MR imaging help identify patients who are candidates for active surveillance?
    Baris Turkbey
    Molecular Imaging Program, Laboratory of Pathology, Radiation Oncology Branch, and Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182 Bldg 10, Room B3B69, Bethesda, MD 20892 1088, USA
    Radiology 268:144-52. 2013
    ....
  17. pmc Adrenal nodular hyperplasia in hereditary leiomyomatosis and renal cell cancer
    Brian Shuch
    Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 1107, USA
    J Urol 189:430-5. 2013
    ....
  18. pmc Decision support system for localizing prostate cancer based on multiparametric magnetic resonance imaging
    Vijay Shah
    National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Med Phys 39:4093-103. 2012
    ..Our goal was to develop a decision support system (DSS) for detecting and localizing peripheral zone prostate cancers by using machine learning approach to calculate a cancer probability map from multiparametric MR images (MP-MRI)...
  19. pmc Use of patient-specific MRI-based prostate mold for validation of multiparametric MRI in localization of prostate cancer
    Hari Trivedi
    Center for Interventional Oncology, Radiology and Imaging Sciences, Clinical Center, Molecular Imaging Program, Urologic Oncology Branch, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 1088, USA
    Urology 79:233-9. 2012
    ..A significant difficulty to date has been accurate correlation between the magnetic resonance images and histopathologic specimens...
  20. pmc Magnetic Resonance Imaging/Transrectal Ultrasonography Fusion Prostate Biopsy Significantly Outperforms Systematic 12-Core Biopsy for Prediction of Total Magnetic Resonance Imaging Tumor Volume in Active Surveillance Patients
    Chinonyerem Okoro
    1 Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland
    J Endourol 29:1115-21. 2015
    ....
  21. doi request reprint Utility of multiparametric magnetic resonance imaging suspicion levels for detecting prostate cancer
    Soroush Rais-Bahrami
    Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland
    J Urol 190:1721-7. 2013
    ..We determine the usefulness of multiparametric magnetic resonance imaging in detecting prostate cancer, with a specific focus on detecting higher grade prostate cancer...
  22. doi request reprint Diagnostic value of biparametric magnetic resonance imaging (MRI) as an adjunct to prostate-specific antigen (PSA)-based detection of prostate cancer in men without prior biopsies
    Soroush Rais-Bahrami
    Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    BJU Int 115:381-8. 2015
    ....
  23. pmc Mutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1
    Meghan L Rudd
    Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda MD 20892, USA
    BMC Cancer 14:884. 2014
    ..The purpose of this study was to search for somatic mutations in the tyrosine kinome of serous and clear cell ECs, because mutated kinases can point to potential therapeutic targets...
  24. doi request reprint Identification by digital immunohistochemistry of intratumoral changes of immune infiltrates after vaccine in the absence of modifications of PBMC immune cell subsets
    Benedetto Farsaci
    Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD
    Int J Cancer 135:862-70. 2014
    ..These studies provide additional rationale for the use of i.t.-s.c. vaccinations and demonstrate a noncoordinate expression of specific immune subsets in PBMCs vs. tumor. ..
  25. doi request reprint The role of image guided biopsy targeting in patients with atypical small acinar proliferation
    Dima Raskolnikov
    Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland
    J Urol 193:473-8. 2015
    ..We describe the ability of magnetic resonance imaging/transrectal ultrasound fusion guided prostate biopsy to detect prostate cancer in areas with an initial diagnosis of atypical small acinar proliferation...
  26. pmc Identification of threshold prostate specific antigen levels to optimize the detection of clinically significant prostate cancer by magnetic resonance imaging/ultrasound fusion guided biopsy
    Nabeel A Shakir
    Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland
    J Urol 192:1642-8. 2014
    ..We evaluated the performance of magnetic resonance imaging/ultrasound targeted biopsy vs 12-core biopsy across a prostate specific antigen continuum...
  27. pmc Localized prostate cancer detection with 18F FACBC PET/CT: comparison with MR imaging and histopathologic analysis
    Baris Turkbey
    From the Molecular Imaging Program B T, E M, M L L, M B, Y L M, S A, P L C, K A K, Biometric Research Branch, Division of Cancer Treatment and Diagnosis J S, Urologic Oncology Branch P A P, and Laboratory of Pathology M J M, National Institutes of Health, National Cancer Institute, 10 Center Dr, MSC 1182 Bldg 10, Room B3B85 Bethesda, MD 20892 1088 and Medical Diagnostics Research and Development, GE Healthcare, Uppsala, Sweden R O
    Radiology 270:849-56. 2014
    ....
  28. pmc Natural history of small index lesions suspicious for prostate cancer on multiparametric MRI: recommendations for interval imaging follow-up
    Soroush Rais-Bahrami
    Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Diagn Interv Radiol 20:293-8. 2014
    ..We aimed to determine the natural history of small index lesions identified on multiparametric-magnetic resonance imaging (MP-MRI) of the prostate by evaluating lesion-specific pathology and growth on serial MP-MRI...
  29. pmc Association of germline mutations in the fumarate hydratase gene and uterine fibroids in women with hereditary leiomyomatosis and renal cell cancer
    Laveta Stewart
    Division of Cancer Epidemiology and Genetics, Genetic Epidemiology Branch, National Cancer Institute, National Institutes of Health, Rockville, MD 20892 7231, USA
    Arch Dermatol 144:1584-92. 2008
    ..To investigate the risk of uterine fibroids and other reproductive risk factors in women with hereditary leiomyomatosis and renal cell cancer (HLRCC)...
  30. doi request reprint Multiparametric 3T prostate magnetic resonance imaging to detect cancer: histopathological correlation using prostatectomy specimens processed in customized magnetic resonance imaging based molds
    Baris Turkbey
    Molecular Imaging Program, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    J Urol 186:1818-24. 2011
    ..Precise one-to-one histopathological correlation with magnetic resonance imaging was possible using prostate magnetic resonance imaging based custom printed specimen molds after radical prostatectomy...
  31. doi request reprint Correlation of magnetic resonance imaging tumor volume with histopathology
    Baris Turkbey
    Molecular Imaging Program, National Cancer Institute, Bethesda, Maryland 20892 1210, USA
    J Urol 188:1157-63. 2012
    ..We determined the accuracy of magnetic resonance imaging for determining index tumor volume compared with volumes derived from histopathology...
  32. pmc Is apparent diffusion coefficient associated with clinical risk scores for prostate cancers that are visible on 3-T MR images?
    Baris Turkbey
    Molecular Imaging Program, Center for Interventional Oncology, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182, Bldg 10, Room B3B69F, Bethesda, MD 20892 1088, USA
    Radiology 258:488-95. 2011
    ....
  33. pmc Documenting the location of systematic transrectal ultrasound-guided prostate biopsies: correlation with multi-parametric MRI
    Baris Turkbey
    National Cancer Institute, NIH, Bethesda, MD, USA
    Cancer Imaging 11:31-6. 2011
    ....
  34. doi request reprint The Role of Magnetic Resonance Image Guided Prostate Biopsy in Stratifying Men for Risk of Extracapsular Extension at Radical Prostatectomy
    Dima Raskolnikov
    Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland
    J Urol 194:105-11. 2015
    ....
  35. doi request reprint Comparison of magnetic resonance imaging and ultrasound (MRI-US) fusion-guided prostate biopsies obtained from axial and sagittal approaches
    Cheng W Hong
    Center for Interventional Oncology, Clinical Center, National Institutes of Health NIH, Bethesda, MD, USA
    BJU Int 115:772-9. 2015
    ..To compare cancer detection rates and concordance between magnetic resonance imaging and ultrasound (MRI-US) fusion-guided prostate biopsy cores obtained from axial and sagittal approaches...
  36. ncbi request reprint Hereditary leiomyomatosis and renal cell cancer: a syndrome associated with an aggressive form of inherited renal cancer
    Robert L Grubb
    Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Urol 177:2074-9; discussion 2079-80. 2007
    ..We report the clinical characteristics and urological treatment of patients with hereditary leiomyomatosis and renal cell cancer associated renal tumors...
  37. pmc Imaging and pathology findings after an initial negative MRI-US fusion-guided and 12-core extended sextant prostate biopsy session
    Cheng William Hong
    From the Center for Interventional Oncology National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Diagn Interv Radiol 20:234-8. 2014
    ..The imaging characteristics and pathology outcomes of subsequent biopsies in patients with initially negative MRI-US fusion biopsies are described in this study...
  38. pmc Comparison of endorectal coil and nonendorectal coil T2W and diffusion-weighted MRI at 3 Tesla for localizing prostate cancer: correlation with whole-mount histopathology
    Baris Turkbey
    Molecular Imaging Program, NCI, NIH, Bethesda, Maryland, USA
    J Magn Reson Imaging 39:1443-8. 2014
    ..To compare utility of T2-weighted (T2W) MRI and diffusion-weighted MRI (DWI-MRI) obtained with and without an endorectal coil at 3 Tesla (T) for localizing prostate cancer...
  39. pmc Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis
    Diane Palmieri
    Women s Cancers Section, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892 7322, USA
    Mol Cancer Res 7:1438-45. 2009
    ..028). The data suggest that HK2 overexpression is associated with metastasis to the brain in breast cancer and it may be a therapeutic target...
  40. ncbi request reprint Nm23-H1 suppresses metastasis by inhibiting expression of the lysophosphatidic acid receptor EDG2
    Christine E Horak
    Women s Cancers Section, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA
    Cancer Res 67:11751-9. 2007
    ..73; P = 0.004). The data indicate that Nm23-H1 down-regulation of EDG2 is functionally important to suppression of tumor metastasis...
  41. doi request reprint Differentiating Transition Zone Cancers From Benign Prostatic Hyperplasia by Quantitative Multiparametric Magnetic Resonance Imaging
    Osama Elbuluk
    From the Molecular Imaging Program, National Cancer Institute, National Institutes of Health, Bethesda, MD iCAD, Inc, Nashua, NH Division of Cancer Treatment and Diagnosis, Biometric Research Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD Imaging Physics, SAIC Frederick, Inc, National Cancer Institute Frederick, Frederick, MD and Laboratory of Pathology, Center for Interventional Oncology, and Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD
    J Comput Assist Tomogr 40:218-24. 2016
    ..The aim of this study was to evaluate the value of quantitative diffusion and perfusion parameters to aid in discriminating between transition zone carcinomas and benign prostatic hyperplasia (BPH)...
  42. doi request reprint PET/CT imaging of renal cell carcinoma with (18)F-VM4-037: a phase II pilot study
    Baris Turkbey
    Molecular Imaging Program, National Cancer Institute, Bethesda, MD, USA
    Abdom Radiol (NY) 41:109-18. 2016
    ..Carbonic anhydrase IX (CA-IX) is a potential imaging biomarker of clear cell renal cell carcinoma (ccRCC). Here, we report the results of a phase II clinical trial of a small molecule radiotracer targeting CA-IX ((18)F-VM4-037) in ccRCC...
  43. doi request reprint Does focal incidental 18F-FDG PET/CT uptake in the prostate have significance?
    Anna M Brown
    Molecular Imaging Program, National Cancer Institute, NIH, 10 Center Drive, Room B3B85, Bethesda, MD, 20892, USA
    Abdom Imaging 40:3222-9. 2015
    ..18)F-FDG PET/CT is used to characterize many malignancies, but is not recommended for localized prostate cancer. This study explores the value of multi-parametric MRI (mpMRI) in characterizing incidental prostate (18)F-FDG uptake...
  44. doi request reprint Use of serial multiparametric magnetic resonance imaging in the management of patients with prostate cancer on active surveillance
    Annerleim Walton Diaz
    Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD
    Urol Oncol 33:202.e1-7. 2015
    ..We evaluated the performance of multiparametric prostate magnetic resonance imaging (mp-MRI) and MRI/transrectal ultrasound (TRUS) fusion-guided biopsy (FB) for monitoring patients with prostate cancer on active surveillance (AS)...
  45. doi request reprint Posterior subcapsular prostate cancer: identification with mpMRI and MRI/TRUS fusion-guided biopsy
    Sandeep Sankineni
    Molecular Imaging Program, NCI, NIH, Bethesda, MD, USA
    Abdom Imaging 40:2557-65. 2015
    ..We retrospectively evaluated the multiparametric MRI (mpMRI) features of subcapsular prostate cancers to make radiologists more aware of this condition...
  46. doi request reprint A Phase I Dosing Study of Ferumoxytol for MR Lymphography at 3 T in Patients With Prostate Cancer
    Baris Turkbey
    1 Molecular Imaging Program, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182, Bldg 10, Rm B3B85, Bethesda, MD 20892 1088
    AJR Am J Roentgenol 205:64-9. 2015
    ..The objective of our study was to determine the optimal dose of ferumoxytol for performing MR lymphography (MRL) at 3 T in patients with prostate cancer...
  47. ncbi request reprint Role of chromogenic in situ hybridization (CISH) in the evaluation of HER2 status in breast carcinoma: comparison with immunohistochemistry and FISH
    Elsa Li-Ning-T
    Laboratory of Pathology, National Cancer Institute, Bethesda, MD 20892, USA
    Int J Surg Pathol 13:343-51. 2005
    ..Chromosome 17 analysis was necessary in cases with a low number of HER2 gene copies. CISH is a useful tool to evaluate breast cancer HER2 status that can be easily implemented in a laboratory of surgical pathology...
  48. doi request reprint miR-145 suppresses thyroid cancer growth and metastasis and targets AKT3
    Myriem Boufraqech
    Endocrine Oncology BranchLaboratory of PathologyNational Cancer Institute, National Institutes of Health, Center for Cancer Research, Bethesda, Maryland 20892, USA
    Endocr Relat Cancer 21:517-31. 2014
    ....
  49. pmc Succinate dehydrogenase kidney cancer: an aggressive example of the Warburg effect in cancer
    Christopher J Ricketts
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    J Urol 188:2063-71. 2012
    ..We report our experience with the diagnosis, evaluation and treatment of this novel form of hereditary kidney cancer...
  50. pmc Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2
    Yukiko Hasumi
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 106:18722-7. 2009
    ....
  51. doi request reprint Can magnetic resonance-ultrasound fusion biopsy improve cancer detection in enlarged prostates?
    Annerleim Walton Diaz
    Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland
    J Urol 190:2020-5. 2013
    ..Magnetic resonance-ultrasound fusion biopsy has shown superior prostate cancer detection rates. We defined the detection rate of magnetic resonance-ultrasound fusion biopsy in men with an enlarged prostate gland...
  52. pmc Germline PTEN mutation Cowden syndrome: an underappreciated form of hereditary kidney cancer
    Brian Shuch
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland
    J Urol 190:1990-8. 2013
    ..Cowden syndrome is a hereditary cancer syndrome associated with a germline mutation in PTEN. Patients are predisposed to multiple malignancies including renal cell carcinoma...
  53. doi request reprint MRI of localized prostate cancer: coming of age in the PSA era
    Baris Turkbey
    Molecular Imaging Program, National Cancer Institute, NIH, Bethesda, MD, USA
    Diagn Interv Radiol 18:34-45. 2012
    ..In this article, we introduce the reader to the expanding roles that MRI plays in the management of localized prostate cancer...
  54. pmc Prostate Cancer: Interobserver Agreement and Accuracy with the Revised Prostate Imaging Reporting and Data System at Multiparametric MR Imaging
    Berrend G Muller
    From the Molecular Imaging Program B G M, S S, P L C, B T, Biometric Research Branch, Division of Cancer Treatment and Diagnosis J H S, Urologic Oncology Branch S R B, A G, P P, Laboratory of Pathology M J M, and Center for Interventional Oncology B J W, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182, Bldg 10, Room B3B85, Bethesda, MD 20892 1088 Department of Urology, AMC University Hospital, Amsterdam, the Netherlands B G M, J J M C H d l R and Department of Radiology and Radiological Sciences, Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD J M
    Radiology 277:741-50. 2015
    ..46 and 0.55. Conclusion Use of the revised PI-RADS provides moderately reproducible MR imaging scores for detection of clinically relevant disease. (©) RSNA, 2015 Online supplemental material is available for this article. ..
  55. doi request reprint Comparison of calculated and acquired high b value diffusion-weighted imaging in prostate cancer
    Kinzya B Grant
    Molecular Imaging Program, National Cancer Institute NCI, NIH 10 Center Dr, MSC 1182, Bldg 10, Room B3B85, Bethesda, MD, 20892 1088, USA
    Abdom Imaging 40:578-86. 2015
    ....
  56. pmc Molecular genetics and cellular features of TFE3 and TFEB fusion kidney cancers
    Eric C Kauffman
    Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Building 10, CRC Room 1 5940, Bethesda, MD 20892, USA
    Nat Rev Urol 11:465-75. 2014
    ..Determining which pathways are most important to RCC oncogenesis will be critical in discovering the most promising therapeutic targets for this disease. ..
  57. pmc Comparison of MR/ultrasound fusion-guided biopsy with ultrasound-guided biopsy for the diagnosis of prostate cancer
    M Minhaj Siddiqui
    Urologic Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland7Dr Siddiqui is now with the Department of Surgery, Division of Urology, University of Maryland, Baltimore
    JAMA 313:390-7. 2015
    ..Targeted magnetic resonance (MR)/ultrasound fusion prostate biopsy has been shown to detect prostate cancer. The implications of targeted biopsy alone vs standard extended-sextant biopsy or the 2 modalities combined are not well understood...
  58. pmc Changes observed in multiparametric prostate magnetic resonance imaging characteristics correlate with histopathological development of chronic granulomatous prostatitis after intravesical Bacillus Calmette-Guerin therapy
    Jennifer K Logan
    From the Urologic Oncology Branch, Laboratory of Pathology, Molecular Imaging Program, and Center for Interventional Oncology, National Cancer Institute, National Institutes of Health, Bethesda, MD
    J Comput Assist Tomogr 38:274-6. 2014
    ..We present serial magnetic resonance imaging and biopsy data demonstrating the time interval between BCG administration and the manifestation of chronic granulomatous prostatitis. ..
  59. ncbi request reprint Differential expression of S100C in thyroid lesions
    Carlos Torres-Cabala
    Surgical Pathology Section, Laboratory of Pathology, National Cancer Institute, NIH, Bethesda, MD, USA
    Int J Surg Pathol 12:107-15. 2004
    ....
  60. pmc A novel germline mutation in BAP1 predisposes to familial clear-cell renal cell carcinoma
    Megan N Farley
    Urologic Oncology Branch, National Cancer Institute, Bldg 10 CRC 1W5940, Bethesda, MD 20892
    Mol Cancer Res 11:1061-71. 2013
    ..These findings suggest that BAP1 is an early-onset familial RCC predisposing gene...
  61. doi request reprint Renal medullary carcinoma: molecular, immunohistochemistry, and morphologic correlation
    Qingyan Liu
    Translational Surgical Pathology and Urologic Oncology sections, National Cancer Institute, Bethesda, MD 20892, USA
    Am J Surg Pathol 37:368-74. 2013
    ..These data suggest that inactivation of SMARCB1 may play a role in the pathogenesis of renal medullary carcinoma...
  62. pmc 11C-Acetate PET/CT in localized prostate cancer: a study with MRI and histopathologic correlation
    Esther Mena
    Molecular Imaging Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    J Nucl Med 53:538-45. 2012
    ....
  63. ncbi request reprint Loss of heterozygosity on chromosome 1 and 9 and hormone receptor analysis of metastatic malignant melanoma presenting in breast
    Michael W Beaty
    Laboratory of Pathology, Surgical Pathology Section, National Cancer Institute, Bethesda, MD 20892, USA
    Int J Surg Pathol 13:9-18. 2005
    ..Additional LOH was observed at the 9q22.3-31 locus (40%). We suggest this locus to be investigated for harboring potential genes important in the tumorigenesis of cutaneous MM...
  64. pmc Documenting the location of prostate biopsies with image fusion
    Baris Turkbey
    Molecular Imaging Program, NCI, NIH, Bethesda, MD, USA
    BJU Int 107:53-7. 2011
    ....
  65. pmc Multiparametric magnetic resonance imaging of the prostate aids detect lesion progression
    Linda M Johnson
    From the Molecular Pharmacology Section, Medical Oncology Branch, and Molecular Imaging Program, National Cancer Institute, Bethesda, MD Urologic Oncology Branch, NCI, NIH, Bethesda, MD Center for Interventional Oncology, Radiology and Imaging Sciences CC, NIH, Bethesda, MD Clinical Pharmacology Program, Center for Cancer Research, National Cancer Institute, Bethesda, MD and Laboratory of Pathology, NCI, NIH, Bethesda, MD
    J Comput Assist Tomogr 38:565-7. 2014
    ....
  66. pmc Predisposition to cancer caused by genetic and functional defects of mammalian Atad5
    Daphne W Bell
    Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Genet 7:e1002245. 2011
    ..Taken together, our findings indicate that loss-of-function mutations in mammalian Atad5 are sufficient to cause genomic instability and tumorigenesis...
  67. ncbi request reprint Renal tumors in the Birt-Hogg-Dubé syndrome
    Christian P Pavlovich
    Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute NIH, Bldg 10 Rm 2N212, Bethesda, MD 20892, USA
    Am J Surg Pathol 26:1542-52. 2002
    ..Recognition by the pathologist of the unusual renal tumors associated with BHD may assist in the clinical diagnosis of the syndrome...
  68. pmc Identification of EpCAM as a molecular target of prostate cancer stroma
    Sumana Mukherjee
    Pathogenetics Unit, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 4605, USA
    Am J Pathol 175:2277-87. 2009
    ..Since the stromal compartment may be particularly accessible to vascular-delivered agents, epithelial cell adhesion activating molecule could become a valuable molecular target for imaging or treatment of prostate cancer...
  69. pmc Prostate cancer: value of multiparametric MR imaging at 3 T for detection--histopathologic correlation
    Baris Turkbey
    Molecular Imaging Program, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182, Bldg 10, Room 1B40, Bethesda, MD 20892 1088, USA
    Radiology 255:89-99. 2010
    ....
  70. doi request reprint Fully automated prostate segmentation on MRI: comparison with manual segmentation methods and specimen volumes
    Baris Turkbey
    1 Molecular Imaging Program, National Cancer Institute, National Institutes of Health, 10 Center Dr, MSC 1182, Bldg 10, Rm B69, Bethesda, MD 20892 1088
    AJR Am J Roentgenol 201:W720-9. 2013
    ....
  71. pmc Pathologic validation of renal cell carcinoma histology in the Surveillance, Epidemiology, and End Results program
    Brian Shuch
    Urologic Oncology Branch, National Cancer Institute, Bethesda, Md Electronic address
    Urol Oncol 32:23.e9-13. 2014
    ..The Surveillance, Epidemiology, and End Results (SEER) program is an important epidemiologic research tool to study cancer. No information is available on its pathologic accuracy for renal cell carcinoma (RCC)...
  72. pmc Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes
    Matthieu Le Gallo
    Cancer Genetics Branch, National Human Genome Research Institute, US National Institutes of Health NIH, Bethesda, MD, USA
    Nat Genet 44:1310-5. 2012
    ....
  73. pmc FOXP3 expression accurately defines the population of intratumoral regulatory T cells that selectively accumulate in metastatic melanoma lesions
    Mojgan Ahmadzadeh
    Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Blood 112:4953-60. 2008
    ....
  74. pmc Sequencing of candidate chromosome instability genes in endometrial cancers reveals somatic mutations in ESCO1, CHTF18, and MRE11A
    Jessica C Price
    Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS ONE 8:e63313. 2014
    ..Our findings warrant future studies to determine whether these mutations are driver events that contribute to the pathogenesis of endometrial cancer...
  75. pmc Genome-wide methylation patterns in papillary thyroid cancer are distinct based on histological subtype and tumor genotype
    Ryan J Ellis
    Endocrine Oncology Branch R J E, M B, D P, N N, M H, L Z, E K, Genetics Branch Y W, H S S, S D, D C E, P S M, and Laboratory of Pathology M J M, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 and Perelman School of Medicine R J E, University of Pennsylvania, Philadelphia, Pennsylvania 19104
    J Clin Endocrinol Metab 99:E329-37. 2014
    ..Aberrant DNA methylation is known to be a major factor in oncogenesis and cancer progression, but effects of methylation in papillary thyroid cancer (PTC) are not well defined...
  76. pmc A unique spectrum of somatic PIK3CA (p110alpha) mutations within primary endometrial carcinomas
    Meghan L Rudd
    Cancer Genetics Branch, National Human Genome Research Institute, National Cancer Institute, Bethesda, Maryland, USA
    Clin Cancer Res 17:1331-40. 2011
    ..The goal of this study was to comprehensively define the incidence of mutations in all exons of PIK3CA in both endometrioid endometrial cancer (EEC) and nonendometrioid endometrial cancer (NEEC)...
  77. doi request reprint Primary neuroendocrine tumors of the kidney: morphological and molecular alterations of an uncommon malignancy
    Phyu P Aung
    Translational Surgical Pathology, Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Hum Pathol 44:873-80. 2013
    ..We conclude that PNRTs are positive for NE markers and may have LOH on chromosome 3p21. PNRTs should be classified as NE tumors in other sites, and proliferative rate can be an indicator of aggressive behavior/metastasis...
  78. pmc Characterization and management of testicular pathology in McCune-Albright syndrome
    Alison M Boyce
    Skeletal Clinical Studies Unit, Craniofacial and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Clin Endocrinol Metab 97:E1782-90. 2012
    ..Radiographic and histological studies are limited to small series and case reports, which report testicular microlithiasis and Sertoli cell hyperplasia...
  79. pmc T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis
    Maria R Parkhurst
    Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Mol Ther 19:620-6. 2011
    ..It also emphasizes the destructive power of small numbers of highly avid T cells and the limitations of using CEA as a target for cancer immunotherapy...
  80. ncbi request reprint CD10 immunohistochemical staining enhances the histological detection of endometriosis
    Clariss Potlog-Nahari
    Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, Bethesda, Maryland 20892 1583, USA
    Fertil Steril 82:86-92. 2004
    ..To determine whether the use of CD10 immunohistochemistry in addition to hematoxylin and eosin (H&E) staining would increase the sensitivity of surgically suspected endometriosis lesions...
  81. doi request reprint Successful treatment of periodontal mucormycosis: report of a case and literature review
    Nancy E McDermott
    National Institute of Dental and Craniofacial Research, Bethesda, Maryland 20892, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109:e64-9. 2010
    ..Calcofluor fluorescence microscopy is also proposed as a method for establishing a prompt diagnosis and guiding extent of intraoperative surgical debridement...
  82. ncbi request reprint Location, color, size, depth, and volume may predict endometriosis in lesions resected at surgery
    Pamela Stratton
    Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1853, USA
    Fertil Steril 78:743-9. 2002
    ..To correlate the diagnosis of endometriosis in lesions excised at laparoscopy with pathologic diagnosis...
  83. pmc Biochemically silent abdominal paragangliomas in patients with mutations in the succinate dehydrogenase subunit B gene
    Henri J L M Timmers
    Reproductive Biology and Medicine Branch, National Institute of Child Health and Human Development, National Institutes of Health, 10 Center Drive, Building 10, CRC, Room 1 E 3140, Bethesda Maryland 20892 1109, USA
    J Clin Endocrinol Metab 93:4826-32. 2008
    ..We report four cases of biochemically silent abdominal PGL, in which metanephrines were normal despite extensive disease...
  84. doi request reprint Phase I study of intraprostatic vaccine administration in men with locally recurrent or progressive prostate cancer
    James L Gulley
    Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 10 Center Dr, 8B09 MSC 1750, Bethesda, MD 20892, USA
    Cancer Immunol Immunother 62:1521-31. 2013
    ..Improved serum PSA kinetics and intense post-vaccination inflammatory infiltrates were seen in the majority of patients. Clinical trials examining clinical end points are warranted...
  85. ncbi request reprint Expression of Birt-Hogg-Dubé gene mRNA in normal and neoplastic human tissues
    Michelle B Warren
    Laboratory of Immunobiology, Center for Cancer Research, NCI Frederick, Frederick, MD, USA
    Mod Pathol 17:998-1011. 2004
    ..These results indicate a wide expression pattern for BHD mRNA in many tissues, including skin, lung and kidney, which are involved in the BHD phenotype, and support a tumor suppressor role for BHD in renal cancer...
  86. ncbi request reprint Rab11a differentially modulates epidermal growth factor-induced proliferation and motility in immortal breast cells
    Diane Palmieri
    Women s Cancers Section, Laboratory of Molecular Pharmacology, Laboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, MD 20874, USA
    Breast Cancer Res Treat 100:127-37. 2006
    ..The data provide a first demonstration that Rab11a modulates EGFR recycling, and promotes the proliferation but inhibits the motility of an immortal breast line, consistent with the DCIS phenotype...
  87. ncbi request reprint Microvessel density, expression of estrogen receptor alpha, MIB-1, p53, and c-erbB-2 in inflammatory breast cancer
    Nicole J McCarthy
    Cancer Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20889, USA
    Clin Cancer Res 8:3857-62. 2002
    ....
  88. pmc Noninvasive monitoring of a murine model of metastatic pheochromocytoma: a comparison of contrast-enhanced microCT and nonenhanced MRI
    Lucia Martiniova
    Reproductive and Adult Endocrinology Program, National Institutes of Child Health and Human Development, Bethesda, Maryland 20892 1109, USA
    J Magn Reson Imaging 29:685-91. 2009
    ..However, the choice of imaging modality is still evolving...
  89. ncbi request reprint Role of metastasectomy in the management of thyroid carcinoma: the NIH experience
    Ho Pak
    Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 1758, USA
    J Surg Oncol 82:10-8. 2003
    ..We studied the impact of metatasectomy on disease outcome in 29 advanced nonmedullary thyroid carcinoma (ThyrCa) patients who were operated on between 1969 and 2001 at NIH to further define its role in the management of this malignancy...
  90. pmc Prospective screening in familial nonmedullary thyroid cancer
    Samira M Sadowski
    Endocrine Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Md Electronic address
    Surgery 154:1194-8. 2013
    ..Approximately 8% of nonmedullary thyroid cancers are familial. The optimal age for screening in familial nonmedullary thyroid cancer (FNMTC) is unknown...
  91. pmc New syndrome of paraganglioma and somatostatinoma associated with polycythemia
    Karel Pacak
    Section on Medical Neuroendocrinology, Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver NICHD, NIH, Bethesda, MD 20892 1109, USA
    J Clin Oncol 31:1690-8. 2013
    ..The occurrence of ≥ two distinct types of tumors, one of them paraganglioma (PGL), is unusual in an individual patient, except in hereditary cancer syndromes...
  92. pmc Enhanced homing permeability and retention of bone marrow stromal cells by noninvasive pulsed focused ultrasound
    Ali Ziadloo
    Laboratory of Diagnostic Radiology Research, Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland 20892, USA
    Stem Cells 30:1216-27. 2012
    ..pFUS could potentially improve cell-based therapies as a noninvasive modality to target homing by establishing local chemoattractant gradients and increasing expression of integrins to enhance tropism of cells toward treated tissues...
  93. doi request reprint Misdiagnosis of clear cell renal cell carcinoma
    Vladimir A Valera
    Translational Surgical Pathology section, Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 10 Center Drive, Building 10, MSC Room 2B44, Bethesda, MD 20892, USA
    Nat Rev Urol 8:321-33. 2011
    ....
  94. doi request reprint Mesothelial neoplasms presenting as, and mimicking, ovarian cancer
    Haresh Mani
    Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Int J Gynecol Pathol 29:523-8. 2010
    ..Mesothelial neoplasms can present as ovarian masses in young women. Awareness of this presentation is important to establish appropriate management...
  95. pmc Expression of benign and malignant thyroid tissue in ovarian teratomas and the importance of multimodal management as illustrated by a BRAF-positive follicular variant of papillary thyroid cancer
    Erin F Wolff
    Program in Reproductive and Adult Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Diabetes, Digestive, and Kidney Diseases, NIH, Bethesda, MD 20892 1613, USA
    Thyroid 20:981-7. 2010
    ..Here we review this topic and illustrate major features by presenting multimodal management of a patient with BRAF-positive disseminated follicular thyroid cancer arising in an ovarian teratoma...
  96. ncbi request reprint Primary synovial sarcoma of the kidney with rhabdoid features
    Mauricio A Paláu L
    Laboratory of Pathology, National Cancer Institute, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Int J Surg Pathol 15:421-8. 2007
    ....
  97. pmc Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer
    James C Yang
    Surgery Branch, Biostatistics and Data Management Section, Department of Pathology, National Cancer Institute NIH, Room 2B 37, Building 10, 9000 Rockville Pike, Bethesda, MD 20892, USA
    J Clin Oncol 21:3127-32. 2003
    ..This three-arm randomized study compares response rates and overall survival of patients with metastatic renal cell cancer (RCC) receiving high-dose or one of two low-dose interleukin-2 (IL-2) regimens...
  98. pmc Administration of a CD25-directed immunotoxin, LMB-2, to patients with metastatic melanoma induces a selective partial reduction in regulatory T cells in vivo
    Daniel J Powell
    Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Immunol 179:4919-28. 2007
    ....
  99. doi request reprint Endometrial endometrioid adenocarcinoma of the uterine corpus involving the cervix: some cases probably represent independent primaries
    Liuyan Jiang
    Department of Pathology, National Cancer Institute, Bethesda, MD, USA
    Int J Gynecol Pathol 29:146-56. 2010
    ..HPV studies are important to identify endocervical tumors associated with high-risk HPV. However, endometrial tumors involving the cervix and endocervical tumors unrelated to HPV are both negative for high-risk HPV...
  100. ncbi request reprint Juxtathyroidal neck soft tissue angiosarcoma presenting as an undifferentiated thyroid carcinoma
    Juan Yu
    Division of Intramural Research, National Institute of Child Health and Human Development, Bethesda, Maryland, USA
    Thyroid 12:427-32. 2002
    ....
  101. ncbi request reprint Localization of medullary thyroid carcinoma metastasis in a multiple endocrine neoplasia type 2A patient by 6-[18F]-fluorodopamine positron emission tomography
    Loukas Gourgiotis
    Clinical Endocrinology Branch, National Institute of Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, 20892, USA
    J Clin Endocrinol Metab 88:637-41. 2003
    ....