X J Meng

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi A novel virus in swine is closely related to the human hepatitis E virus
    X J Meng
    Hepatitis Viruses Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 7 Center Drive, MSC 0740, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 94:9860-5. 1997
  2. ncbi Genetic and experimental evidence for cross-species infection by swine hepatitis E virus
    X J Meng
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Virol 72:9714-21. 1998
  3. ncbi Recombinant hepatitis E virus genomes infectious for primates: importance of capping and discovery of a cis-reactive element
    S U Emerson
    Molecular Hepatitis and Hepatitis Viruses Sections, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 98:15270-5. 2001
  4. ncbi Prevalence of antibodies to the hepatitis E virus in pigs from countries where hepatitis E is common or is rare in the human population
    X J Meng
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland
    J Med Virol 59:297-302. 1999
  5. ncbi Hepatitis E virus (HEV) capsid antigens derived from viruses of human and swine origin are equally efficient for detecting anti-HEV by enzyme immunoassay
    R E Engle
    Hepatitis Viruses and Molecular Hepatitis Sections, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    J Clin Microbiol 40:4576-80. 2002
  6. ncbi Evidence that the genomic RNA of hepatitis E virus is capped
    Y Kabrane-Lazizi
    Hepatitis Viruses and Molecular Hepatitis Sections, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892
    J Virol 73:8848-50. 1999

Detail Information

Publications6

  1. ncbi A novel virus in swine is closely related to the human hepatitis E virus
    X J Meng
    Hepatitis Viruses Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 7 Center Drive, MSC 0740, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 94:9860-5. 1997
    ..The discovery of swine HEV not only has implications for HEV vaccine development, diagnosis, and biology, but also raises a potential public health concern for zoonosis or xenozoonosis following xenotransplantation with pig organs...
  2. ncbi Genetic and experimental evidence for cross-species infection by swine hepatitis E virus
    X J Meng
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Virol 72:9714-21. 1998
    ..These results provided experimental evidence for cross-species infection by the swine virus. Thus, humans appear to be at risk of infection with swine HEV or closely related viruses...
  3. ncbi Recombinant hepatitis E virus genomes infectious for primates: importance of capping and discovery of a cis-reactive element
    S U Emerson
    Molecular Hepatitis and Hepatitis Viruses Sections, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 98:15270-5. 2001
    ..One mutation differentiating the two clones identified a cis-reactive element that appeared to overlap the 3' end of the capsid gene and part of the 3' noncoding region. Capping of the RNA transcripts was essential for infectivity...
  4. ncbi Prevalence of antibodies to the hepatitis E virus in pigs from countries where hepatitis E is common or is rare in the human population
    X J Meng
    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland
    J Med Virol 59:297-302. 1999
    ..The results from this study suggest that hepatitis E is enzootic in pigs regardless of whether HEV is endemic in the respective human population. J. Med. Virol. 59:297-302, 1999. Published 1999 Wiley-Liss, Inc...
  5. ncbi Hepatitis E virus (HEV) capsid antigens derived from viruses of human and swine origin are equally efficient for detecting anti-HEV by enzyme immunoassay
    R E Engle
    Hepatitis Viruses and Molecular Hepatitis Sections, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
    J Clin Microbiol 40:4576-80. 2002
    ..938). Moreover, we found virtually no difference in the levels of prevalence of anti-HEV as measured by the two tests, again suggesting that the antigens derived from human and swine HEV contain the same immunodominant epitopes...
  6. ncbi Evidence that the genomic RNA of hepatitis E virus is capped
    Y Kabrane-Lazizi
    Hepatitis Viruses and Molecular Hepatitis Sections, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892
    J Virol 73:8848-50. 1999
    ..Antibody to m(7)G bound RNA extracted from virions of two different HEV genotypes. The cap analog competitively inhibited the binding of virion RNAs, demonstrating that HEV has a capped RNA genome...